Search clinical trials for: Glycerol phenylbutyrate

Total 212 results

Technical University of Munich

Recruiting

PROFIL Study to Investigate the Effect of GPB on NfL Levels in Patients With Corticobasal Syndrome (CBS) (PROFIL)

Corticobasal Syndrome (CBS)

Germany
Kaplan Medical Center
Weizmann Institute of Science

Recruiting

Glycerol-Phenylbutyrate Treatment in Children With MCT Mutation (Allan-Herndon- Dudley Syndrome)

Monocarboxylate Transporter 8 Deficiency

Israel
Columbia University

Not yet recruiting

PBA Use for Treatment of ATF6-/- Patients

Achromatopsia | ACHROMATOPSIA 7

United States
Weill Medical College of Cornell University
Children's Hospital Colorado; SLC6A1 Connect; STXBP1 Foundation; Clara Inspired; University... and other collaborators

Enrolling by invitation

Phenylbutyrate for Monogenetic Developmental and Epileptic Encephalopathy

Developmental and Epileptic Encephalopathy | STXBP1 Encephalopathy With Epilepsy, SLC6A1 Neurodevelopmental Disorder

United States
Horizon Therapeutics, LLC

Completed

Study of Glycerol Phenylbutyrate & Sodium Phenylbutyrate in Phenylbutyrate Naïve Patients With Urea Cycle Disorders (UCDs)

Urea Cycle Disorder

United States, Spain, Italy, Switzerland
University of Colorado, Denver

Completed

Phenylbutyrate Response as a Biomarker for Alpha-synuclein Clearance From the Brain

Parkinson's Disease

United States
National Jewish Health
Johns Hopkins University; Children's Hospital of Philadelphia; University of... and other collaborators

Terminated

Glycerol Phenylbutyrate Corrector Therapy For CF (Cystic Fibrosis) (GPBA)

Cystic Fibrosis

United States
Horizon Therapeutics, LLC

Terminated

Observational Study That Will Collect Information on Patients With Urea Cycle Disorders (UCDs) (THRIVE)

Urea Cycle Disorder

United States
Horizon Therapeutics, LLC

Completed

A Study of the Safety, Efficacy and Pharmacokinetics of Glycerol Phenylbutyrate in Pediatric Subjects Under 2 Years of Age With Urea Cycle Disorders

Urea Cycle Disorder

United States, Canada
Robert Squires, Jr.

No longer available

Expanded Access Protocol for an Intermediate Size Population - RAVICTI for Byler Disease

Byler Disease
University of Pittsburgh
Horizon Pharma Ireland, Ltd., Dublin Ireland

Completed

Use of Ravicti™ in Patients With MCAD Deficiency With the 985A>G (K304E) Mutation

Medium-chain Acyl-CoA Dehydrogenase (MCAD) Deficiency

United States
Horizon Pharma Ireland, Ltd., Dublin Ireland

Completed

Study of the Safety, Pharmacokinetics and Efficacy of HPN-100, in Pediatric Subjects With Urea Cycle Disorders (UCDs)

Urea Cycle Disorders

United States
Horizon Pharma Ireland, Ltd., Dublin Ireland

Completed

Efficacy and Safety of HPN-100 for the Treatment of Adults With Urea Cycle Disorders

Urea Cycle Disorders

United States, Canada
Horizon Pharma Ireland, Ltd., Dublin Ireland

Completed

A Study of Safety and Efficacy of HPN-100 in Subjects With Cirrhosis and Episodic Hepatic Encephalopathy (HALT-HE)

Hepatic Encephalopathy | Cirrhosis

United States
University of Pittsburgh

No longer available

Transition From Buphenyl to RAVICTI for the Therapy of Byler Disease

Byler Disease
Emory University
Centers for Disease Control and Prevention

Not yet recruiting

Response to Emerging Antimicrobial Resistance With Containment Microbiota Therapy (REACT)

Multi-Drug Resistant Organism Colonization

United States
PepsiCo Global R&D

Recruiting

Effect of Glycerol-Electrolyte Beverages on Fluid Balance in Healthy Euhydrated Men and Women at Rest

Hydration

United States
Jerry Vockley, MD, PhD
Acer Therapeutics Inc.

Recruiting

Study of Sodium Phenylbutyrate (ACER-001) for the Treatment of Patients With Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD)

Medium-chain Acyl-CoA Dehydrogenase Deficiency

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Treatment of Insomnia in Patients With Breast Cancer

Breast Cancer | Insomnia

Italy
KK Women's and Children's Hospital
Singapore General Hospital; Duke-NUS Graduate Medical School; Genome Institute... and other collaborators

Recruiting

Saline Enema Administration in Meconium Obstruction of Prematurity and Impact on the Resolution, Feeds, Microbiome, and Gut-brain Axis.

Meconium Obstruction of Prematurity

Singapore
Centre hospitalier de l'Université de Montréal...

Recruiting

Validation of a System Using Aerosol Glycerine to Detect and Localize Intraoperatively Pulmonary Air Leaks (CT0136)

Air Leak From Lung

Canada
Maastricht University

Not yet recruiting

Role of BCAA in Glucose Homeostasis (NaPB2)

Type 2 Diabetes
Indiana University

Recruiting

Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen

Constipation

United States
University Hospital, Basel, Switzerland

Recruiting

Effect of Glyceroltrinitrate on Human Energy Expenditure and Brown Adipose Tissue Thermogenesis (NEXT)

Brown Adipose Tissue

Switzerland
Wills Eye

Recruiting

A Multi-Center Study on the Use of Rho-Kinase Inhibitor to Reduce or Prevent PVR in RRD Eyes at High Risk for PVR

Rhegmatogenous Retinal Detachment | Proliferative Vitreoretinopathy

United States
Universitat Internacional de Catalunya
Klockner Implant System

Not yet recruiting

Citric Acid Passivation on Implant Abutments for the Prevention of Peri-implant Disease

Peri-Implantitis | Implant Infection | Microbial Disease
Nova Scotia Health Authority
Dalhousie University

Not yet recruiting

The Effects of Glycerol as an Optical Clearing Agent for Visualization of the Middle Ear

Healthy | Surgery | Tympanosclerosis | Thickened Ears
Peking Union Medical College Hospital

Recruiting

A Prospective Study of the Effect of Modified Colonoscopy Bowel Preparation Program on Intestinal Cleaning, Examination and Disease in Patients With Inflammatory Bowel Disease

Inflammatory Bowel Diseases

China
Medical College of Wisconsin

Recruiting

Loncastuximab Tesirine in Combination With DA-EPOCH-R in Patients With Previously Untreated Aggressive B-cell Lymphoid Malignancies (LONCA)

B-cell Lymphoma | Burkitt Lymphoma

United States
Zhujiang Hospital
Dongguan People's Hospital; Shantou Central Hospital; Shenzhen Hengsheng Hospital and other collaborators

Recruiting

Safety and Efficacy of Human Microbiota Transplantation for Overweight and Obese Type 2 Diabetes Mellitus (SETOM)

Type 2 Diabetes Mellitus | Overweight and Obesity

China
University of Nottingham

Recruiting

The Effects of Sodium Phenylbutyrate on Circulating Branched Chain Amino Acids

Obese Non Diabetic

United Kingdom
Peking University First Hospital

Recruiting

The Efficacy and Safety of 12-week SOF/VEL Regimen Combined With Prophylactic Use of TAF for Treatment-naïve Genotype 1-6 HCV/HBV Co-infection Adult Patients With or Without Compensated Cirrhosis in China (BDTAF)

Chronic Hepatitis B | Chronic Hepatitis C

China
424 General Military Hospital
Aristotle University Of Thessaloniki

Recruiting

Nitrate Use to Obtain Radial Spasm Embarrassment (NURSE - TTS Trial) (NURSE-TTS)

Radial Artery Spasm

Greece
Guang'anmen Hospital of China Academy of Chinese...
National Natural Science Foundation of China; Special Project of National Traditional...

Not yet recruiting

Efficacy and Safety of Wen Xin Granules for the Treatment of Unstable Angina Pectoris

Coronary Heart Disease | Unstable Angina | Chinese Herbal Medicine
National Cancer Institute (NCI)

Recruiting

Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults

B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1

United States, Puerto Rico, Israel
Tanta University

Recruiting

Ethosuximide and Pentoxifylline in the Treatment of Abdominal Pain Related to Irritable Bowel Syndrome

IBS - Irritable Bowel Syndrome

Egypt
University of Aarhus

Recruiting

Comparison of Transanal Irrigation and Glycerol Suppositories in Treatment of Low Anterior Resection Syndrome

Low Anterior Resection Syndrome | Rectal Cancer

Denmark
Centre Hospitalier Universitaire, Amiens

Recruiting

Monitoring of the Bone Free Flaps With Microdialysis (MTM2018)

Flap Necrosis

France
National Cancer Institute (NCI)

Recruiting

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

Down Syndrome | B Acute Lymphoblastic Leukemia | B Lymphoblastic Lymphoma

United States, Canada, Puerto Rico, Australia, New Zealand
National Cancer Institute (NCI)

Recruiting

Inotuzumab Ozogamicin and Blinatumomab in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

Recurrent B Acute Lymphoblastic Leukemia | Refractory B Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

United States
Global United Pharmaceutical Corporation

Not yet recruiting

Assessing the Efficacy of CREWS01 to Decrease Usage of Rescue Inhalers in Moderate to Severe Asthmatic Adults (CREWS01)

Asthma

United States
National Cancer Institute (NCI)

Active, not recruiting

Lenalidomide and Blinatumomab for the Treatment of Relapsed Non-Hodgkin Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Recurrent Small Lymphocytic Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia | Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1

United States
Amylyx Pharmaceuticals Inc.
ALS Association; ALS Finding a Cure; Northeast ALS Consortium; Neurological Clinical... and other collaborators

Completed

AMX0035 in Patients With Amyotrophic Lateral Sclerosis (ALS) (CENTAUR)

Central Nervous System Diseases | Nervous System Diseases | Neuromuscular Diseases | Neurodegenerative Diseases | Motor Neuron Disease | Amyotrophic Lateral Sclerosis | Spinal Cord Diseases | TDP-43 Proteinopathies

United States
Amylyx Pharmaceuticals Inc.

Active, not recruiting

AMX0035 in Adult Patients With Wolfram Syndrome

Wolfram Syndrome

United States
University of Edinburgh
NHS Lothian; DexCom, Inc.; Tandem Diabetes Care, Inc.; The Leona M. and Harry B...

Active, not recruiting

Maximising Time With a Normal Blood Glucose to Restore the Glucagon Response in Type 1 Diabetes

Hypoglycemia | Type 1 Diabetes | Type 1 Diabetes Mellitus With Hypoglycemia | Hypoglycemia Unawareness | Glucagon Deficiency | Insulin Hypoglycemia

United Kingdom
Emory University
Centers for Disease Control and Prevention

Completed

Sentinel Cohort REACT

Multi-Drug Resistant Organism

United States
King Faisal Specialist Hospital & Research Center
Security Forces Hospital; Dr. Sulaiman Alhabib Medical City, Riyadh

Terminated

Efficacy of Prophylactic Glycerin Suppositories for Feeding Intolerance in Very Low Birth Weight Preterm Infants: a Randomized Trial

Infant, Very Low Birth Weight

Saudi Arabia
Emory University
United States Department of Defense

Completed

Treatment of Encopresis in Children With Autism Spectrum Disorders

Autism Spectrum Disorder | Encopresis

United States
Oregon Health and Science University

Completed

Fatty Acid Oxidation Defects and Insulin Sensitivity

Normal Volunteers | Trifunctional Protein Deficiency | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Long-chain 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Carnitine Palmitoyltransferase II Deficiency, Myopathic

United States

Search clinical trials for: Glycerol phenylbutyrate

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