Search clinical trials for: Graft-versus-host betegség

Total 374941 results

Henry M. Jackson Foundation for the Advancement...
Uniformed Services University of the Health Sciences; Brooke Army Medical Center

Not yet recruiting

Ketamine for Sedation in Severe Traumatic Brain Injury (Ketamine)

Intracranial Hypertension | Severe Traumatic Brain Injury | Intracranial Hemorrhage, Hypertensive
Sijia Gu

Recruiting

Prospective Clinical Trial for Children With TCRαβ Depleted vs Traditional Haplo Identicle HSCT

Child, Only | Hematopoietic Stem Cell Transplantation | Graft-Versus-Host Disease | Haploidentical Hematopoietic Stem Cell Transplantation

China
IRCCS Ospedale San Raffaele

Not yet recruiting

Validation of Human Drugs Target of Repurposed Drugs and Novel Therapies

Rare Diseases | Corneal Neovascularization | Limbal Stem Cell Deficiency | Aniridia | Neurotrophic Keratopathy | Ocular Cicatricial Pemphigoid | Ocular Graft-versus-host Disease | EEC Syndrome
University of Wisconsin, Madison

Not yet recruiting

Dose-Escalation Trial of Mesenchymal Stromal Cells in Patients With Medical Xerostomia

Xerostomia | Graft-versus-host-disease | Sjogren's Disease

United States
Incyte Corporation

Not yet recruiting

A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease

Chronic Graft-versus-host-disease
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

Study on the Serum Metabolic Markers and Early Complications After Allo-HSCT： Cohort Study

Acute Graft Versus Host Disease | Acute Kidney Injury | Stem Cell Transplant Complications | Major Adverse Cardiac Events
Hospital Universitario Dr. Jose E. Gonzalez

Recruiting

Evaluation of Safety & Efficacy for the Prevention of Ocular GVHD With Ophthalmic Tacrolimus vs Cyclosporine in Allo-HSCT

Ocular Graft-versus-host Disease

Mexico
ReAlta Life Sciences, Inc.

Not yet recruiting

Safety, PK, PD, Dosing, and Efficacy of RLS-0071for the Treatment of Hospitalized Patients With Steroid-Refractory Acute Graft-versus-Host Disease (AURORA)

Steroid Refractory GVHD
University of Palermo

Recruiting

SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography (SYMILIS OCT)

Oral Disease | Oral Cancer | Actinic Keratoses | Oral Leukoplakia | Oral Squamous Cell Carcinoma | Oral Lichen Planus | Graft-versus-host-disease | Proliferative Verrucous Leukoplakia | Actinic Cheilitis | Oral Potentially Malignant Disorder | Oral Erythroplakia | Oral Lichenoid Lesion

Italy
Anhui Provincial Hospital

Recruiting

A Trial to Evaluate the Safety and Preliminary Efficacy of iMesenchymal Stromal Cells(iMSC) in Subjects With SR-aGVHD

Steroid-refractory Acute Graft-versus-host Disease(SR-aGVHD)

China
Fundación Oftalmológica de Santander Clínica Carlos...
Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud - IDCBIS

Not yet recruiting

Sequential Administration of WJ-MSCs for the Treatment of GvHD Refractory to Second Line Treatment (GvHD)

Graft Versus Host Disease
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

A Clinical Trial of TQ05105 Tablets in the Treatment of Chronic Graft-versus-host Disease

Chronic Graft Versus Host Disease

China
Anhui Provincial Hospital

Not yet recruiting

Effect of Stem Cell Infusion Time on aGVHD in Patients With Nonmalignant Hematologic Diseases

Acute Graft-versus-host Disease

China
Anhui Provincial Hospital

Not yet recruiting

Effect of Stem Cell Infusion Time on aGVHD in Patients With Hematological Malignancies

Acute Graft-versus-host Disease

China
University of Seville

Not yet recruiting

Physical Therapy in Patients Undergoing Allo-HSCT With cGVHD

Stem Cell Transplant Complications | Graft-versus-host-disease | Hematological Malignancy | Hematologic Cancer | Graft Versus Host Disease, Chronic

Spain
Peking University People's Hospital

Not yet recruiting

Sirolimus+Abatacept+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to Calcineurin Inhibitors

Myelodysplastic Syndromes | Acute Leukemia | Severe Aplastic Anemia
Mayo Clinic

Not yet recruiting

Ibrutinib for the Prevention of Chronic Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplant

Chronic Graft Versus Host Disease | Hematopoietic and Lymphatic System Neoplasm

United States
Incyte Biosciences Japan GK

Not yet recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Axatilimab Monotherapy in Japanese Participants With Recurrent or Refractory Active Chronic Graft-Versus-Host Disease

Chronic Graft-versus-host-disease
Nantes University Hospital

Not yet recruiting

Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft Transplantation (CY-MET-RIC)

Hematologic Malignancy | Graft Versus Host Disease
University Hospital, Bordeaux

Recruiting

Tissue Immune Landscape of Graft Versus Host Disease After Allogeneic Stem Cell Transplantation (TIL-GVHD) (TIL-GVHD)

Chronic Graft Versus Host Disease

France
Beijing 302 Hospital

Not yet recruiting

Combination of ATG-based Conditioning Regimen and PTCy for GVHD Prevention in Allo-HSCT After PD-1 Blockade

Hematological Malignancies | Graft-versus-host Disease
Stefanie Sarantopoulos, MD, PhD.
National Institutes of Health (NIH); Incyte Corporation; Rigel Pharmaceuticals

Not yet recruiting

Ruxolitinib Plus Fostamatinib for Steroid Refractory cGvHD

Chronic Graft Versus Host Disease

United States
Ugur Arzu Kulu

Recruiting

Correlation of Serum Gasdermin-D and NLRP-3 Inflammasome Levels With GVHD Biomarkers and Endothelial Damage Markers in Graft-Versus-Host Disease

Endothelial Dysfunction | Graft Versus Host Disease | Acute Myeloid Leukemia, Adult

Turkey
Abbisko Therapeutics Co, Ltd

Recruiting

A Phase II Study Evaluating the Efficacy and Safety of ABSK021 (Pimicotinib)) in the Treatment of cGvHD Chronic Graft Versus Host Disease (cGvHD)

cGvHD

China
Beijing Tide Pharmaceutical Co., Ltd

Not yet recruiting

TDI01 Suspension in the Treatment of Chronic Graft-versus-host Disease (cGVHD))

GVHD, Chronic
University of Miami

Recruiting

Horizons Chronic Graft-Versus-Host-Disease Study

Quality of Life | Coping Skills | Graft Vs Host Disease | Stem Cell Transplant Complications

United States
Southwest Hospital, China
Xinqiao Hospital of Chongqing

Recruiting

Treatment of Oral Chronic Graft-versus-host Disease With Human Umbilical Cord Mesenchymal Stem Cell Dressing

Mesenchymal Stem Cells

China
Sanofi

Recruiting

A Study to Test an Oral Medicine, Belumosudil, in Combination With Corticosteroids in Participants at Least 12 Years of Age With Newly Diagnosed Chronic Graft Versus Host Disease. (ROCKnrol-1)

Chronic Graft Versus Host Disease

Australia, Argentina, Belgium, Spain, Sweden, Czechia, United Kingdom, United States, Italy, Germany, Canada, Israel, Denmark, Brazil, Turkey
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States
medac GmbH

Recruiting

Trial of Efficacy and Safety of MC0518 Versus Best Available Therapy in Participants With Steroid-Refractory Acute Graft Versus Host Disease (BALDER)

Steroid-refractory Acute Graft-versus-host Disease

Germany, Spain, France, Poland
Northside Hospital, Inc.
Sanofi

Recruiting

Belumosudil and Rituximab for Primary Treatment of Chronic Graft-Versus-Host-Disease

Chronic Graft Versus Host Disease

United States
Fred Hutchinson Cancer Center

Recruiting

Fecal Microbiota Transplantation for the Prevention of Acute Graft Versus Host Disease in Adults Undergoing Allogeneic Hematopoietic Cell Transplantation

Acute Graft Versus Host Disease | Hematopoietic and Lymphatic System Neoplasm

United States
Washington University School of Medicine
Incyte Corporation

Recruiting

Ruxolitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

Graft Versus Host Disease | Graft Vs Host Disease | Graft-versus-host-disease

United States
Shanghai Jiao Tong University School of Medicine
Shanghai Clinical Research Center

Not yet recruiting

Comparison of Different Dose of Post-transplantation Cyclophosphamide as Graft Versus Host Disease Prophylaxis

GVHD

China
Fred Hutchinson Cancer Center
Sanofi

Recruiting

Belumosudil for the Pre-emptive Treatment of Patients With Chronic Graft Versus Host Disease

Chronic Graft Versus Host Disease

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation

Chronic Graft Versus Host Disease | Hematologic and Lymphocytic Disorder | Steroid Refractory Graft Versus Host Disease

United States
Rabin Medical Center

Not yet recruiting

Letermovir Prophylaxis for Cytomegalovirus (CMV) in Patients With Graft-versus-host Disease

CMV | Graft-versus-host-disease
Neena Kapoor, M.D.

Not yet recruiting

TCRαβ/CD19 Depletion of Stem Cell Grafts for Transplant

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Hematologic Malignancy | Graft Vs Host Disease | Graft-versus-host-disease | Non-hematologic Malignancy
University Hospital, Basel, Switzerland

Recruiting

Effect of Ketanserin, Olanzapine, and Lorazepam After LSD Administration on the Acute Response to LSD in Healthy Subjects (LBL)

Healthy

Switzerland
Hoffmann-La Roche

Recruiting

A Study to Evaluate the Safety and Effectiveness of Trastuzumab Emtansine (T-DM1) as Therapy in Chinese Participants With HER2 Positive Advanced Breast Cancer

Breast Cancer

China
Dana-Farber Cancer Institute
Sanofi; National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

BElumosudil for Bronchiolitis Obliterans Prevention/Therapy (BEBOP)

Chronic Graft Versus Host Disease | Lung Diseases | Bronchiolitis Obliterans | Bronchiolitis Obliterans Syndrome

United States
Peking University People's Hospital

Recruiting

Mini-dose MTX Plus Standard-dose Steroid for the Initial Treatment of Acute GVHD

Acute Graft Versus Host Disease

China
Incyte Corporation

Recruiting

Observational Study for Patients at Risk for Chronic Graft-Versus-Host Disease (THRIVE)

cGVHD

United States
University of Michigan Rogel Cancer Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Parametric Response Mapping (PRM) for the Detection of Chronic Lung Injury in Hematopoietic Cell Transplant Recipients

Chronic Lung Disease | Graft Versus Host Disease | Hematopoietic Cell Transplantation

United States
Biotech Pharmaceutical Co., Ltd.

Recruiting

Safety and Clinical Activity of Itolizumab in aGVHD

Acute Graft Versus Host Disease

China
Soonchunhyang University Hospital

Recruiting

Intestinal Microbiome-based Research for the Prevention of Acute GVHD

Graft Versus Host Disease | Postbiotics | Butyrate

Korea, Republic of
Hospices Civils de Lyon

Recruiting

Thymoglobulin® Pharmacokinetics in Patients Undergoing Hematopoietic Stem Cell Transplantation (PHASAL-GA)

Hematopoietic Stem Cell Transplantation-Associated Thrombotic Microangiopathy

France
Henry Ford Health System

Recruiting

CXCL9 and EASIX for Prediction of Acute Graft Versus Host Disease

GVHD,Acute

United States
University of British Columbia

Recruiting

Polyomic Biomarker Verification in Adult Chronic Graft-Versus-Host Disease (ABLE3.0/CTTC2201)

Leukemia | Allogeneic Hematopoietic Stem Cell Transplantation | Blood Cancer | Chronic Graft-versus-Host-Disease | Non-Malignant Hematologic and Lymphocytic Disorder

United States, Canada
Massachusetts General Hospital
The Leukemia and Lymphoma Society

Recruiting

Psychosocial Mobile App for Chronic Graft-Versus-Host Disease

Allogeneic Stem Cell Transplant | Chronic Graft-Versus-Host Disease

United States

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