Search clinical trials for: Hedgehog inhibitor
Total 67811 results
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University Hospital, LilleSun Pharmaceutical Industries LimitedNot yet recruitingBasal Cell Carcinoma | Radiotherapy; Complications
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Ronald BuckanovichGenentech, Inc.RecruitingPARP Inhibitor | Platinum-Resistant Fallopian Tube Carcinoma | Platinum-Resistant Primary Peritoneal Carcinoma | Hedgehog InhibitorUnited States
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St. Jude Children's Research HospitalRecruitingMedulloblastomaUnited States
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Maastricht University Medical CenterSun Pharmaceutical Industries LimitedRecruitingCarcinoma | Carcinoma, Basal Cell | Skin Cancer | Basal Cell Nevus Syndrome | Neoplasms, Basal Cell | Basal Cell Carcinoma | Locally Advanced Basal Cell Carcinoma | Metastatic Basal Cell Carcinoma | Gorlin Syndrome | Basal Cell Tumor | Neoplasm of SkinNetherlands
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Hangzhou Cancer HospitalRecruitingEsophageal Diseases | Esophageal Squamous Cell Carcinoma | Esophageal NeoplasmChina
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National Cancer Institute (NCI)Active, not recruitingGlioma | Hematopoietic and Lymphoid Cell Neoplasm | Melanoma | Lymphoma | Multiple Myeloma | Recurrent Ovarian Carcinoma | Breast Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Lung Carcinoma | Recurrent Skin Carcinoma | Gastric Carcinoma | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory... and other conditionsUnited States, Puerto Rico, Guam
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Regeneron PharmaceuticalsSanofiCompletedCarcinoma, Basal CellUnited States, Canada, France, Italy, Spain, Germany, Belgium, Austria, Greece, Switzerland
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PfizerCompletedHematologic MalignanciesUnited States, Italy
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Ascend Biopharmaceuticals LtdCompletedBasal Cell Nevus Syndrome | Basal Cell CarcinomaAustralia
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St. Jude Children's Research HospitalEli Lilly and CompanyActive, not recruitingBrain Cancer | Brain Tumor | Medulloblastoma | Brain Tumor, Recurrent | CNS Tumor | Medulloblastoma Recurrent | CNS Cancer | Medulloblastoma, Non-WNT/Non-SHH | Brain Tumor, Pediatric | CNS Neoplasm | Brain Tumor, Refractory | Medulloblastoma, Non-WNT/Non-SHH, Group 3 | Medulloblastoma, Non-WNT/Non-SHH, Group 4United States
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St. Jude Children's Research HospitalNovartis PharmaceuticalsActive, not recruitingGlioma | Neoplasms | Glioblastoma | Neoplasms, Neuroepithelial | Central Nervous System Neoplasms | Brain Cancer | Brain Tumor | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Pineoblastoma | Recurrent Medulloblastoma | CNS Tumor | Pediatric... and other conditionsUnited States
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National Cancer Institute (NCI)Active, not recruitingPancreatic Ductal Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage IV Pancreatic Cancer AJCC v6 and v7 | Pancreatic Acinar Cell Carcinoma | Adult Solid NeoplasmUnited States
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PfizerCompleted
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OHSU Knight Cancer InstituteOregon Health and Science UniversityTerminatedPrimary Myelofibrosis | Anemia | Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Anatomic Stage IV Breast Cancer AJCC v8 | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Refractory Myelodysplastic... and other conditionsUnited States
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OHSU Knight Cancer InstituteGenentech, Inc.; Oregon Health and Science UniversityWithdrawnAnatomic Stage III Breast Cancer AJCC v8 | Recurrent Ovarian Carcinoma | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Advanced Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Recurrent... and other conditionsUnited States
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St. Jude Children's Research HospitalNational Cancer Institute (NCI); Genentech, Inc.Active, not recruitingMedulloblastomaUnited States, Canada, Australia, New Zealand
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Endeavor Biomedicines, Inc.Active, not recruitingSolid Tumors With PTCH1 Loss-of-function MutationsUnited States
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Endeavor Biomedicines, Inc.CompletedIdiopathic Pulmonary FibrosisAustralia
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Sarit AssoulineCompleted
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Sol-Gel Technologies, Ltd.TerminatedRecurrent Basal Cell CarcinomaUnited States
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PfizerCompletedLeukemia, Myeloid, AcuteUnited States, Spain, Canada, Israel, Korea, Republic of, Taiwan, France, Australia, Germany, Mexico, Japan, Sweden, China, Austria, Belgium, Czechia, Hungary, Italy, Poland, Romania, Russian Federation, United Kingdom
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Grupo Espanol de trasplantes hematopoyeticos y...Active, not recruitingSclerodermoid Chronic Graft-Versus-Host Disease (Disorder)Spain
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University of Colorado, DenverThe Leukemia and Lymphoma SocietyCompletedRecurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia in RemissionUnited States
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Dallas VA Medical CenterActive, not recruitingEsophageal CancerUnited States
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H. Lee Moffitt Cancer Center and Research InstitutePfizerCompletedChronic Myelomonocytic Leukemia (CMML) | Myelodysplastic Syndrome (MDS)United States
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UCSF Benioff Children's Hospital OaklandGenentech, Inc.CompletedBasal Cell Nevus Syndrome | Gorlin SyndromeUnited States
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National Cancer Institute (NCI)CompletedExtensive Stage Small Cell Lung Carcinoma | Recurrent Small Cell Lung CarcinomaUnited States
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Novartis PharmaceuticalsCompletedAdvanced Solid TumorUnited States
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Novartis PharmaceuticalsCompletedMedulloblastoma | Basal Cell Carcinoma | Advanced Solid Tumor CancersSpain, Switzerland, United Kingdom, United States
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Novartis PharmaceuticalsCompletedMedulloblastoma | Basal Cell Carcinoma | Advanced Solid Tumor CancersTaiwan, Hong Kong, Japan
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Novartis PharmaceuticalsCompletedMetastatic Colorectal Cancer | Gastric Cancer | Advanced Solid Tumors | Metastatic Breast Cancer | Gastroesophageal Junction Cancer | Recurrent Glioblastoma Multiforme | Advanced Pancreatic Adenocarcinoma | Safety | Triple Negative Metastatic Breast Cancer | Dose Escalation | Preliminary Efficacy | Hormone Receptor...Canada, United Kingdom, Spain, Germany, Italy, Belgium, Australia, United States
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Novartis PharmaceuticalsCompletedAdvanced Solid Tumors | Recurrent or Refractory Medulloblastoma | Locally Advanced or Metastatic Basal Cell CarcinomaUnited States, United Kingdom, Switzerland, Netherlands
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Novartis PharmaceuticalsCompletedBone Marrow Diseases | Hematologic Diseases | Blood Coagulation Disorders | Hemorrhagic Disorders | Primary Myelofibrosis | Myeloproliferative Disorders | Polycythemia Vera | Thrombocytosis | Essential Thrombocythemia | Blood Platelet DisordersUnited Kingdom, Belgium, Canada, France, Australia, Netherlands, Spain, Denmark, Ireland, Italy, Germany
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PfizerCompletedAcute Myeloid LeukemiaUnited States, Spain, Germany, Italy, Poland, Canada
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Sidney Kimmel Comprehensive Cancer Center at Johns...Novartis Pharmaceuticals; The Skip Viragh FoundationTerminatedPancreatic Ductal AdenocarcinomaUnited States
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Swiss Group for Clinical Cancer ResearchCompleted
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Hospital de Clinicas de Porto AlegreUnknownBasal Cell Carcinoma | Hedgehog PathwayBrazil
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Sidney Kimmel Comprehensive Cancer Center at Johns...Genentech, Inc.; Celgene Corporation; Stand Up To CancerCompletedMetastatic Pancreatic CancerUnited States
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Jason K. Sicklick, M.D.Novartis PharmaceuticalsCompletedHepatocellular Carcinoma | CirrhosisUnited States
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PellePharm, Inc.Completed
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National Cancer Institute (NCI)CompletedRecurrent Uterine Corpus Sarcoma | Chondrosarcoma | Recurrent Osteosarcoma | Gastrointestinal Stromal Tumor | Clear Cell Sarcoma of the Kidney | Metastatic Osteosarcoma | Ovarian Sarcoma | Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage III Uterine Sarcoma | Stage IV Adult... and other conditionsUnited States
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Clinica Universidad de Navarra, Universidad de...Unknown
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Memorial Sloan Kettering Cancer CenterNovartis PharmaceuticalsCompleted
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National Cancer Institute (NCI)CompletedRecurrent Pancreatic Carcinoma | Stage IV Pancreatic CancerUnited States
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Genentech, Inc.Completed
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Genentech, Inc.Completed
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Genentech, Inc.Completed
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Novartis PharmaceuticalsWithdrawnBasal Cell CarcinomaGreece, Switzerland, Germany, United Kingdom, Belgium, Canada, Czechia, Finland, Italy, Spain
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Novartis PharmaceuticalsCompletedGlioma | Astrocytoma | Medulloblastoma | Neuroblastoma | Rhabdomyosarcoma | HepatoblastomaFrance, Canada, Italy, Australia, United Kingdom, United States