Search clinical trials for: Hematopoietic stem cells

Total 24312 results

Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Chemotherapy, Radiation Therapy, Rituximab, and Umbilical Cord Blood Transplant in Treating Patients With B-Cell Non-Hodgkin's Lymphoma

Lymphoma | Leukemia

United States
Polyphor Ltd.

Completed

Safety and Efficacy of POL6326 for Mobilization of Hematopoietic Stem Cells in Healthy Volunteers

Healthy

Germany
M.D. Anderson Cancer Center

Completed

Vorinostat With Gemcitabine, Busulfan, and Melphalan With Stem Cell Transplant (SCT) in Relapsed or Refractory Lymphoid Malignancies

Lymphoma

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Stem Cell Transplantation and T-Cell Add-Back to Treat Bone Marrow Malignancies

Hematologic Malignancies | Bone Marrow Transplant Rejection

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Dose Monitoring of Busulfan and Combination Chemotherapy in Hodgkin or Non-Hodgkin Lymphoma Undergoing Stem Cell Transplant

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Genzyme, a Sanofi Company

Completed

Plerixafor Plus Granulocyte Colony-stimulating Factor (G-CSF) For Mobilization And Collection Of Peripheral Hematopoietic Stem Cells In Japanese Participants With Multiple Myeloma

Multiple Myeloma

Japan
BioLineRx, Ltd.

Completed

A Phase I Study Evaluating Safety, Tolerability, PK and PD of BL-8040 for Stem Cell Mobilization in Healthy Volunteers

Mobilization of Hematopoietic Stem Cells (HSC) to Peripheral Blood (PB)

Israel
Burnasyan Federal Medical Biophysical Center

Unknown

Effectiveness and Safety of MMSCs for Enhancing Hematopoietic Recovery and Prophylaxis of Neutropenic Enterocolitis

Neutropenic Enterocolitis | Myeloablative Chemotherapy Induced Bone Marrow Aplasia

Russian Federation
City of Hope Medical Center
National Cancer Institute (NCI); National Institute of Allergy and Infectious...

Completed

Measuring Changes in Blood in Patients at High Risk of Cytomegalovirus Infection After Undergoing Donor Bone Marrow Transplant or Peripheral Blood Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Nonneoplastic Condition | Myelodysplastic/Myeloproliferative Neoplasms
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

A Standardized Nursing Intervention Protocol for HCT Patients

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Psychosocial Effects of Cancer and Its Treatment | Myelodysplastic/Myeloproliferative Neoplasms | Therapy-related Toxicity

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

Total Marrow and Total Lymph Node Irradiation, Fludarabine, and Melphalan Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Hematological Cancer That Has Not Responded to Treatment

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With HIV-Associated Non-Hodgkin or Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Nanfang Hospital of Southern Medical University

Unknown

Unrelated Umbilical Cord Blood Following HLA-haploidentical Hematopoietic Stem Cell Transplantation in Patients With β-thalassemia Major

Thalassemia Major

China
Navy General Hospital, Beijing
Peking Union Medical College Hospital; Cancer Institute and Hospital, Chinese... and other collaborators

Unknown

Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia

Severe Aplastic Anemia

China
Hospital Universitario Dr. Jose E. Gonzalez

Completed

Effect of Intrathecal Administration of Hematopoietic Stem Cells in Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Mexico
University of Arkansas

Terminated

Study of Hyperbaric Oxygen Therapy in Addition to Standard Growth Factor Support for Hematopoietic Progenitor/Stem Cell Mobilization

Multiple Myeloma

United States
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Sun Yat-sen University; Shanghai Zhongshan... and other collaborators

Unknown

MSC for Treatment of CMV Infection

Hematological Diseases | Stem Cell Transplantation, Hematopoietic | CMV Infection

China
Sanofi

Completed

Evaluation of Plerixafor Plus G-CSF to Mobilize and Collect 5×10^6CD34+ Cells/kg in Non-Hodgkin's Lymphoma (NHL) Patients for Autologous Transplantation

Non-Hodgkin's Lymphoma

China
Shanghai General Hospital, Shanghai Jiao Tong University...
The First Affiliated Hospital with Nanjing Medical University; The First Affiliated... and other collaborators

Unknown

ATG Could Improve the Outcome Of Hematopoietic Stem Cell Transplant in Patients With Highly Aggressive T Cell Tumors (HSCT)

Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma

China
Indiana University School of Medicine
National Institutes of Health (NIH)

Withdrawn

In-Vitro Studies in Depletion of Haplotype Mismatched Alloreactive T Cells

Hematopoietic Stem Cell Transplantation | Hematologic Malignancies
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Sun Yat-sen University; Guangzhou First... and other collaborators

Unknown

MSCs With or Without Peripheral Blood Stem Cell for Treatment of Poor Graft Function and Delayed Platelet Engraftment

Hematological Diseases | Stem Cell Transplantation, Hematopoietic | Delayed Platelet Engraftment | Poor Graft Function

China
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Sun Yat-sen University; Guangzhou First... and other collaborators

Unknown

MSCs Combined With CD25 Monoclonal Antibody and Calcineurin Inhibitors for Treatment of Steroid-resistant aGVHD

Acute Graft-versus-host Disease

China
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Small Intestine Cancer | Infection | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Graft Versus Host Disease | Myelodysplastic/Myeloproliferative Neoplasms | Secondary Myelofibrosis

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Administration of Rapidly Generated Multivirus-specific Cytotoxic T-Lymphocytes (VIRAGE)

Epstein-Barr Virus Infections | Stem Cell Transplant | Cytomegalovirus Infections | Adenovirus Infection

United States
Aldagen

Terminated

ALD-101 Adjuvant Therapy of Unrelated Umbilical Cord Blood Transfusion (UCBT) in Patients With Inherited Metabolic Diseases (UCBT-002)

Mucopolysaccharidosis | Inborn Errors of Metabolism | Lysosomal Storage Disorders | Inherited Metabolic Diseases | Peroxisomal Storage Diseases

United States
University Hospital, Clermont-Ferrand

Completed

Mobilization by Plerixafor of Haematopoietic Stem Cells in Children (MEP1)

Children Cancer, Solid Tumor

France
TME Pharma AG

Completed

NOX-A12 Multiple Ascending Dose Study in Healthy Volunteers (SNOXA12C101)

Hematopoietic Stem Cell Transplantation

Germany
Karolinska Institutet

Unknown

A Pilot Study Using Placenta Derived Decidual Stromal Cells for Toxicity and Inflammation With Special Focus to the Allogeneic Hematopoietic Cell Transplantation Setting

Inflammation | Stem Cell Transplantation | Acute Lung Injury | Decidual Stromal Cells

Sweden
Vedic Lifesciences Pvt. Ltd.
Stem Vida International

Completed

Study to Assess the Effect of StemAlive® Supplement on the Levels of Stem Cells in Human Volunteers (Hematoalive)

Healthy

India
Polyphor Ltd.

Completed

Exploratory Study on POL6326 in Stem Cell Mobilization

Multiple Myeloma

Germany
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Sun Yat-sen University; Shanghai Zhongshan... and other collaborators

Unknown

Peripheral Blood Stem Cell Combined With Mesenchymal Stem Cells for Treatment of Poor Graft Function

Hematological Diseases | Stem Cell Transplantation, Hematopoietic | Poor Graft Function

China
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Treated T Cells Followed by a Stem Cell Transplant in Treating Patients With Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

United States
Cancer Research UK

Unknown

High-Dose Chemotherapy Given Together With Peripheral Blood Stem Cell Transplant in Treating Patients With Intestinal T-Cell Lymphoma

Lymphoma | Small Intestine Cancer

United Kingdom
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm

United States
University of California, San Francisco

Terminated

Pilot Study of Umbilical Cord Blood Transplantation in Adult Patient With Advanced Hematopoietic Malignancies

Acute Myeloid Leukemia | Multiple Myeloma | Hodgkin Disease | Lymphoma, Mantle-Cell | Acute Lymphoblastic Leukemia | Lymphoma, T-Cell, Peripheral | Chronic Myelogenous Leukemia | Myelodysplasia | Lymphoma, Large-Cell, Diffuse | T-NK Cell Lymphoma

United States
University Hospital, Clermont-Ferrand
Pierre Fabre Laboratories

Unknown

Eradication of Residual Disease by Preemptive Immunointervention After Allogeneic Hematopoietic Stem Cells Transplantation in Chronic Lymphocytic Leukemia (RICAC)

Chronic Lymphocytic Leukemia | Lymphocytic Lymphoma

France
M.D. Anderson Cancer Center

Completed

Purged Circulating Tumor Cells (CTCs) From Metastatic Breast Cancer

Breast Cancer | Invasive Breast Carcinoma | Metastatic Breast Carcinoma

United States
Asan Medical Center

Completed

Donor Stem Cell Transplant After Conditioning Therapy in Treating Patients With Hematologic Cancer, Recurrent or Metastatic Solid Tumor, or Other Disease

Lymphoma | Myelodysplastic Syndromes | Leukemia | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Nonmalignant Neoplasm

Korea, Republic of
Fondazione Italiana Linfomi ONLUS

Completed

Prognosis of Patients With Relapsed/Refractory Hodgkin Lymphoma Treated With IGEV Induction Therapy Before HDCT With AHSCT (IIL-ProHLRec)

Hodgkin's Lymphoma

Italy
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Sun Yat-sen University; Guangzhou First... and other collaborators

Unknown

Mesenchymal Stem Cells Combined With Cord Blood for Treatment of Graft Failure

Mesenchymal Stem Cells | Hematopoietic Stem Cell Transplantation | Hematological Diseases | Graft Failure | Umbilical Cord Blood

China
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Sun Yat-sen University; Guangzhou First... and other collaborators

Unknown

Mesenchymal Stem Cells for Treatment of Poor Graft Function After Allogeneic Hematopoietic Stem Cell Transplant

Mesenchymal Stem Cells | Hematological Diseases | Stem Cell Transplantation, Hematopoietic | Poor Graft Function

China
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Sun Yat-sen University; Guangzhou First... and other collaborators

Unknown

Mesenchymal Stem Cells for Treatment of Refractory Acute Graft-versus-host Disease

Acute Graft-versus-host Disease

China
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Sun Yat-sen University; Guangzhou First... and other collaborators

Unknown

Mesenchymal Stem Cells for Treatment of Refractory Chronic Graft-versus-host Disease

Chronic Graft-versus-host Disease

China
Asan Medical Center

Unknown

Haploidentical Stem Cell Transplantation for Children With Acquired Severe Aplastic Anemia

Acquired Aplastic Anemia

Korea, Republic of
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Donor Stem Cell Transplant in Treating Older or Frail Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm

United States
University of California, San Francisco
National Cancer Institute (NCI)

Withdrawn

Busulfan and Fludarabine Before Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Anemia | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases

United States
M.D. Anderson Cancer Center

Completed

Cellular Therapy With Cord Blood Cells

Lymphoma | Leukemia | Multiple Myeloma

United States
Stanford University
National Institutes of Health (NIH)

Completed

Enrichment & Purging of Stem Cells in Non-Hodgkin's Lymphoma

Lymphoma, Non-Hodgkin

United States
Medipost Co Ltd.

Completed

Safety and Efficacy Study of Umbilical Cord Blood-Drived Mesenchymal Stem Cells to Promote Engraftment of Unrelated Hematopoietic Stem Cell Transplantation

Acute Leukemia

Korea, Republic of
Samsung Medical Center
Medipost Co Ltd.

Unknown

Umbilical Cord Blood-derived Mesenchymal Stem Cells for the Treatment of Steroid-refractory Acute or Chronic Graft-versus-host-disease (GVHD-MSC)

Graft-Versus-Host Disease | GVHD | Disorder Related to Transplantation | Allogeneic Hematopoietic Transplant

Korea, Republic of

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