Search clinical trials for: Hemolytic

Total 1683 results

University of Alabama at Birmingham

Not yet recruiting

Early Life Exposures Among Children With Sickle Cell Disease

Sickle Cell Disease | Breastfeeding | Adverse Childhood Experiences

United States
BILLOIR

Recruiting

Study of Erythrocyte Parameters and Hypercoagulability in Sickle Cell Disease (SCD-TGA) (SCD-TGA)

Sickle Cell Disease | Vaso-occlusive Crisis

France
Assiut University

Not yet recruiting

The Prevelence of IVS 1-6 (T-C) [HBB:c.92 +6 T-C] Gene Mutation in Suspected Cases of β Thalassemia in Assiut University Hospitals

Beta-Thalassemia
University of California, Irvine
Ann & Robert H Lurie Children's Hospital of Chicago; Children's Hospital Los... and other collaborators

Recruiting

Exercise in Child Health (Project REACH)

Cystic Fibrosis | Sickle Cell Disease | SARS CoV 2 Infection

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia

Sickle Cell Anemia | Beta Thalassemia

United States
Hangzhou Zede Pharma-Tech Co., Ltd.

Recruiting

Long-term Clinical Study of CN128 in Thalassemia With Sever Liver Iron Overloaded Patients

Iron Overload | Thalassemia

China
Vertex Pharmaceuticals Incorporated
CRISPR Therapeutics

Recruiting

Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Transfusion-Dependent β-Thalassemia (TDT)

Hematologic Diseases | Genetic Diseases, Inborn | Hemoglobinopathies | Thalassemia | Beta-Thalassemia

United States, Germany, Italy, United Kingdom, Canada
David Williams
National Heart, Lung, and Blood Institute (NHLBI); bluebird bio; California Institute... and other collaborators

Recruiting

A Gene Transfer Study Inducing Fetal Hemoglobin in Sickle Cell Disease (GRASP, BMT CTN 2001) (GRASP)

Sickle Cell Disease

United States
Pfizer

Recruiting

A Study to Evaluate the Long-term Safety of Inclacumab Administered to Participants With Sickle Cell Disease

Sickle Cell Disease | Vaso-occlusive Pain Episode in Sickle Cell Disease | Vaso-occlusive Crisis

United States, Colombia, Brazil, Oman, Nigeria, Italy, Kenya, Lebanon, Turkey, Germany, Saudi Arabia, Tanzania
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

The Montreal Cognitive Assessment.Test in Adults With Sickle Cell Disease (EvaCAD)

Sickle Cell Anemia

France
University of Alabama at Birmingham

Recruiting

Cognitive Remediation Intervention to Prepare for Transition of Care

Cognitive Impairment | Sickle Cell Disease | Self Efficacy | Coping Skills | Health-Related Behavior | Adolescent Behavior

United States
Andria Ford
Novartis Pharmaceuticals

Recruiting

Study of Crizanlizumab for Prevention of Silent Cerebral Infarcts in SCA (CRIZ)

Sickle Cell Disease

United States
Vertex Pharmaceuticals Incorporated
CRISPR Therapeutics

Recruiting

Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Severe Sickle Cell Disease (SCD)

Sickle Cell Disease | Hemoglobinopathies | Hematological Diseases | Hydroxyurea Failure | Hydroxyurea Intolerance

United States, Italy, United Kingdom, Germany
Swiss Federal Institute of Technology
Mahidol University

Not yet recruiting

Inhibitory Effect of a Polyphenol Supplement on Dietary Iron Absorption in Adults With Thalassemia

Iron Overload | Thalassemia

Thailand
Gliknik Inc.

Recruiting

Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Male and Female Subjects and Safety, Tolerability, Pharmacokinetics, and Pilot Efficacy Biomarkers in Subjects With Cold Agglutinin Disease

First in Man Study to Evaluate Initial Safety

United Kingdom
Assiut University

Not yet recruiting

Study on the Effect of Different Risk Factors on the Growth Parameters of Thalassemic Patients in Assiut (AUCH)

Thalassemia Major
University of Florida
National Human Genome Research Institute (NHGRI)

Recruiting

CHOICES3: Sickle Cell Disease Parenting CHOICES (CHOICES3)

Sickle Cell Disease | Sickle Cell Trait

United States
University Hospital, Geneva
Hospices Civils de Lyon; University Hospital, Toulouse

Recruiting

Hyperbaric-oxygen Therapy (HBOT) Versus Placebo for Treating Vaso-Occlusive Crisis (VOC) in Sickle Cell Disease (SCD) (HBOT-SCD)

Sickle Cell Disease | Vaso-occlusive Crisis | Hyperbaric Oxygen Therapy

France, Switzerland
Brown University
National Heart, Lung, and Blood Institute (NHLBI); Novartis

Recruiting

Promoting Utilization and Safety of Hydroxyurea Using Precision in Africa (PUSHUP)

Sickle Cell Disease | Sickle Cell Anemia in Children

Angola
Alexion Pharmaceuticals, Inc.

Recruiting

Real Life Use of Ravulizumab in Italian Patients With Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria

Italy
Zhejiang University
Yake Biotechnology Ltd.

Recruiting

A Clinical Study of CD19/BCMA CAR-T Cells in the Treatment of Refractory POEMS Syndrome, Amyloidosis, Autoimmune Hemolytic Anemia, and Vasculitis

Vasculitis | Amyloidosis | Autoimmune Hemolytic Anemia | POEMS Syndrome

China
Nirmish Shah

Recruiting

AB1 in Adult Patients With Sickle Cell Disease (SCD) ((SCD))

Sickle Cell Disease

United States
Westat
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients (RBC-IMPACT)

Sickle Cell Disease | Thalassemia | Pediatric Cancer

United States, Brazil
University of Lagos, Nigeria

Recruiting

Low Dose Aspirin for Preventing Intrauterine Growth Restriction and Preeclampsia in Sickle Cell Pregnancy (PIPSICKLE) (PIPSICKLE)

Pregnancy Complications | Sickle Cell Disease | Preeclampsia | Intrauterine Growth Restriction

Nigeria
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Adding Azathioprine/Hydroxyurea Preconditioning to Alemtuzumab/TBI to Reduce Risk of Graft Failure in MSD HSCT in Adult SCD Patients

Sickle Cell Disease

Netherlands
Hero Scientific

Recruiting

Detection of Group A β-Hemolytic Streptococci in Oral Samples

Group A β-Hemolytic Streptococci

Israel
University of Calgary
Medical University of South Carolina; University of Colorado, Denver; The Hospital... and other collaborators

Recruiting

Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection (HIKO-STEC)

Hemolytic-Uremic Syndrome | Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection

United States, Canada
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies

Mortality in Sickle Cell | Sickle Cell Cardiopulmonary Complications | Sickle Cell Organ Damage | Sickle Cell Life Expectancy and Risk Factors for Early Death | Sickle Cell Lung Disease and Sudden Death

United States
University of Tennessee
National Heart, Lung, and Blood Institute (NHLBI); University of Illinois at... and other collaborators

Recruiting

The Predictive Capacity of Machine Learning Models for Progressive Kidney Disease in Individuals With Sickle Cell Anemia (PREMIER)

Sickle Cell Disease | Kidney Diseases, Chronic

United States
Centre Hospitalier Universitaire de Nice

Recruiting

Screening for Renal Complications in Children and Young Adults With Major Sickle Cell Disease (NEPHRO-DREPA)

Anemia | Sickle Cell Disease

France
Enrico M Novelli

Recruiting

Cutaneous Hydration Assessment in SCD

Sickle Cell Disease

United States
Assistance Publique - Hôpitaux de Paris
Pfizer

Recruiting

Hemolysis Related Complications in SCD. A Phase II Study With Voxelotor (HEMOPROVE)

Sickle Cell Disease

France
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Preservation and Transfer of HBV Immunity After Allogeneic HSCT for SCD (PROTECT)

Sickle Cell Disease

Netherlands
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Nasopharyngeal Bacterial Carriage and Antibiotic Resistance in Children With Sickle Cell Disease in Ile-De-France (DREPANO-BACT)

Sickle Cell Disease
Agios Pharmaceuticals, Inc.

Recruiting

A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Not Regularly Transfused, Followed by a 5-Year Extension Period (ACTIVATE-Kids)

Pediatric Pyruvate Kinase Deficiency | Pediatric Hemolytic Anemia

United States, Spain, Germany, Netherlands, Canada, France, Israel, Switzerland, Italy
National Institutes of Health Clinical Center (CC)
National Heart, Lung, and Blood Institute (NHLBI); National Human Genome Research...

Recruiting

Dietary Intake and Dietary Behaviors in Adults With Sickle Cell Disease

Sickle Cell Disease

United States
Fulcrum Therapeutics

Recruiting

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of FTX-6058

Sickle Cell Disease | Sickle Cell Anemia

United States
Vanderbilt University Medical Center
Johns Hopkins University; Emory University; Children's National Research Institute

Recruiting

Cooperative Assessment of Late Effects for SCD Curative Therapies (COALESCE)

Heart Disease | Sickle Cell Disease | Pulmonary Disease | Renal Disease

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Severe Acute Respiratory Syndrome CoV 2 COVID-19 Survey and Vaccination Coverage in the Sickle Cell Population in Ile-De-France (COVIDO-DREP)

Sickle Cell Disease
Vanderbilt University Medical Center

Recruiting

Sickle Cell Disease Obstetric Multi-Disciplinary Care Programme (SCOB-II)

Pregnancy Related | Sickle Cell Disease

Ghana
Assiut University

Recruiting

The Prevelence of HBB c.93-21 G-A in β Thalassemia Patients

Beta-Thalassemia

Egypt
Regeneron Pharmaceuticals

Recruiting

A C5 Inhibitor-controlled Study to Evaluate the Efficacy and Safety of Pozelimab and Cemdisiran Combination Therapy in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Are Complement Inhibitor Treatment-Naive or Have Not Recently Received Complement Inhibitor Therapy (ACCESS-1)

Paroxysmal Nocturnal Hemoglobinuria

Mexico, Korea, Republic of, Turkey, Italy, United Kingdom, Thailand, Poland, Singapore, Spain, Taiwan, Canada, Japan, United States, Malaysia, Greece, Romania, Hungary
Assiut University

Not yet recruiting

Assessment of Cognitive Functions, Psychological Symptoms, and Quality of Life Among B Thalassemia Patients and Their Clinical Correlates.

B Thalassemia
Children's National Research Institute

Recruiting

Feasibility and Efficacy of Attentional-Control Training in Sickle Cell Disease (ACT)

Sickle Cell Disease | Cognitive Deficit in Attention | Attention Deficit

United States
Centre Hospitalier Universitaire Dijon

Recruiting

Efficacy of Prolonged Anticoagulation for Primary Prevention of Venous Thromboembolic Disease in Autoimmune Hemolytic Anemia: a Prospective, Phase II, Randomized, Multicenter Study (API-AHAI)

Autoimmune Hemolytic Anemia | Venous Thromboembolic Disease | Prolonged Anticoagulation

France
Indiana University
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Telemedicine for Children With Sickle Cell Disease

Anemia, Sickle Cell

United States
Assistance Publique - Hôpitaux de Paris
INSERM U 1163 - Laboratory of molecular mechanisms of hematologic disorders...

Recruiting

Interest of Famotidine in Children With Sickle Cell Disease (FAMODREP)

Sickle Cell Disease

France
Hoffmann-La Roche

Recruiting

A Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab as Adjunct Treatment in Prevention of Vaso-Occlusive Episodes (VOE) in Sickle Cell Disease (SCD) (CROSSWALK-c)

Sickle Cell Disease

United States, Spain, Brazil, United Kingdom, Italy, Turkey, Kenya, Netherlands, France, South Africa, Lebanon
Assiut University

Recruiting

Second-line Treatment of Primary Autoimmune Hemolytic Anemia

Primary Autoimmune Hemolytic Anemia

Egypt
Centre Hospitalier Intercommunal Creteil
Etablissement Français du Sang; Centre National de la Recherche Scientifique...

Recruiting

Long-term Comparative Cerebrovascular Outcome After Transplantation vs Standard Care in Sickle Cell Anemia (DREPAGREFFE2)

Sickle Cell Disease | Stenosis | Cerebral Ischemia

France

Search clinical trials for: Hemolytic

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