Search clinical trials for: High-risk molecular features

Total 97620 results

M.D. Anderson Cancer Center
Bristol-Myers Squibb

Withdrawn

Urelumab (CD137 mAb) With Rituximab for Relapsed, Refractory or High-risk Untreated Chronic Lymphocytic Leukemia (CLL) Patients

Leukemia
Cancer Research Antwerp
Bayer; Veracyte, Inc.

Recruiting

Treatment of High-Risk Prostate Cancer Guided by Novel Diagnostic Radio- and Molecular Tracers (THUNDER)

Prostate Cancer

Belgium
Shandong Provincial Hospital

Recruiting

Clinicopathological Features and Molecular Typing of Invasive Fibroma of Abdominal Wall

Aggressive Fibromatosis of Abdominal Wall (Disorder)

China
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co....

Not yet recruiting

A Bridging Study of Liposomal Cytarabine-Daunorubicin in Treating Olderly Patients With Treatment-naive High-Risk (Secondary) Acute Myeloid Leukemia

High-risk (Secondary) Acute Myeloid Leukemia

China
University of California, San Francisco
Jazz Pharmaceuticals

Not yet recruiting

Defibrotide Prophylaxis of Transplant Associated-Thrombotic Microangiopathy for Neuroblastoma

Thrombotic Microangiopathies | Neuroblastoma | High-risk Neuroblastoma | Transplant-Associated Thrombotic Microangiopathy

United States
Jules Bordet Institute
KU Leuven; University of Milan

Not yet recruiting

Ketorolac and Pregabalin Effects on breaSt Cancer (KePreSt) (KePreSt)

Early-stage Breast Cancer | Estrogen-receptor-positive Breast Cancer

Belgium
Sun Yat-sen University

Recruiting

Predictive Value of Serum and Tissue Molecular Markers and Imaging Features in the Invasiveness and Prognosis of Pituitary Neuroendocrine Tumors

Pituitary Adenoma | Neuroendocrine Tumors

China
Institut d'Investigació Biomèdica de Bellvitge

Recruiting

Integrating Molecular, Genomic, Morphology and Environmental Features to Improve Precision Diagnosis and Treatment in Interstitial Lung Diseases (PRECISION-ILD) (PRECISION-ILD)

Interstitial Lung Disease | Interstitial Fibrosis

Spain
Central Hospital, Nancy, France

Recruiting

Clinical, Radiological, Histologic and Molecular Features of a Cohort of Melanocytic Tumors of the Central Nervous System (MelaMen)

Meningeal Melanocytoma | Meningeal Melanomatosis | Meningeal Melanocytosis | Meningeal Melanoma

France
Fudan University

Recruiting

Circulating Tumor DNA Methylation Guided Postoperative Adjuvant Chemotherapy for High-risk Stage II/III Colorectal Cancer

Stage III Colorectal Cancer | High-risk Stage II Colorectal Cancer | Circulating Tumor DNA Methylation

China
Lebanese University
Hospital Saydet Zgharta University Medical Center

Recruiting

LUSZ Treatment Efficacy in Hospitalized COVID-19 Patients (LUSZ_AVIST)

COVID-19 | Hospitalized COVID-19 Patients

Lebanon
Peking University People's Hospital

Not yet recruiting

Study and Transformation of Tumor Molecular Features Screening Model of Endometrial Carcinoma Surgical Approach

Endometrial Carcinoma | Tumor Molecular Features Screening Model
Sun Yat-sen University

Recruiting

HAIC Plus A+T for Patients With High-risk HCC: a Single-arm Phase 2 Trial

Hepatocellular Carcinoma

China
David Bond, MD

Recruiting

Tafasitamab and Lenalidomide Followed by Tafasitamab and ICE as Salvage Therapy for Transplant Eligible Patients With Relapsed/ Refractory Large B-Cell Lymphoma

Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Recurrent... and other conditions

United States
Jennifer Crombie, MD
Genentech, Inc.

Recruiting

A Phase II Study of Glofitamab Plus Polatuzumab-R-CHP for Patients With High-risk Diffuse Large B-cell Lymphoma

Lymphoma | Lymphoma, Large B-Cell, Diffuse

United States
University of Chicago

Recruiting

Behavioral Treatment and Memantine in Body Focused Repetitive Behaviors

Trichotillomania (Hair-Pulling Disorder) | Skin-Picking

United States
Tanta University
Eman Ibrahim Elberri, Faculty of Pharmacy, Tanta University; Fedaa Abd El-monem... and other collaborators

Recruiting

Clinical Study to Evaluate the Possible Efficacy of Metformin in Patients With Parkinson's Disease

Parkinson Disease

Egypt
Qilu Hospital of Shandong University

Recruiting

The Clinical Features and Pregnancy Outcomes of RA Patients

Rheumatoid Arthritis | Pregnancy Related

China
Kite, A Gilead Company

Recruiting

Study to Compare Axicabtagene Ciloleucel With Standard of Care Therapy as First-line Treatment in Participants With High-risk Large B-cell Lymphoma (ZUMA-23)

High-risk Large B-cell Lymphoma (LBCL)

United States, Austria, Spain, Italy, Australia, Germany, Netherlands, Canada, Portugal, United Kingdom, France
Institut Curie

Recruiting

Characterisation of the Immune Infiltrate and Molecular Features of Thymic Epithelial Tumors Tumors (TETs) (IMMUNO-TET)

Cancer

France
Hospices Civils de Lyon

Recruiting

Predictive Clinical Features for Response to Adjuvant Immunotherapy in Stage II,III and IV Resected Melanoma (Mel-ImmAdj)

Melanoma

France
Giselle Sholler
Y-mAbs

Recruiting

Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma

High-risk Neuroblastoma

United States, Canada
National Cancer Institute (NCI)

Recruiting

Testing the Safety of the Anti-Cancer Drugs Durvalumab and Olaparib During Radiation Therapy for Locally Advanced Unresectable Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Unresectable Pancreatic Carcinoma | Locally Advanced Pancreatic Carcinoma

United States, Canada
Zhujiang Hospital

Recruiting

Single Arm Study of Post-transplant Azacitidine and Chidamide for Prevention of Acute Myelogenous Leukemia Relapse

Leukemia, Myeloid, Acute

China
Leiden University Medical Center
Canadian Institutes of Health Research (CIHR); AstraZeneca; National Cancer Institute... and other collaborators

Recruiting

Refining Adjuvant Treatment IN Endometrial Cancer Based On Molecular Features (RAINBO)

Endometrial Cancer

Netherlands, Canada, France, United Kingdom
General University Hospital, Prague

Not yet recruiting

Early Salvage Therapy for Patients With Advanced Features for Biochemical Relapse After Radical Prostatectomy for Localized Prostate Carcinoma In Correlation With Supposed Molecular-genetic Parameters of Higher Aggressiveness (ESTABLISH)

Prostate Cancer
University Hospital, Brest

Recruiting

AVAJAK: Apixaban/Rivaroxaban Versus Aspirin for Primary Prevention of Thrombo-embolic Complications in JAK2V617F-positive Myeloproliferative Neoplasms (AVAJAK)

Polycythemia Vera | Essential Thrombocythemia | High-risk Patients | Prefibrotic/Early Primary Myelofibrosis | JAK2 V617F

France
H. Lee Moffitt Cancer Center and Research Institute
United States Department of Defense; Sharp Clinical Services, Inc

Recruiting

Using Aspirin to Improve Immunological Features of Ovarian Tumors

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer

United States
West China Hospital

Recruiting

FOLFOXIRI for Neoadjuvant Treatment of High-risk Locally Advanced Colorectal Cancer

Neoadjuvant Chemotherapy | High-risk Locally Advanced Colorectal Cancer | FOLFOXIRI Regimen

China
Qilu Hospital of Shandong University

Recruiting

The Clinical Features and Pregnancy Outcomes of CTD Patients

Connective Tissue Diseases | Pregnancy Related

China
Korea University Guro Hospital

Recruiting

Comprehensive Assessment of Interconnection Between Brain Emotional Activity and Coronary Plaque Instability

Inflammation | Atherosclerosis | Acute Coronary Syndrome | Emotional Stress | Atherosclerosis, Coronary | Hematopoiesis | Atherosclerosis Coronary Artery With Angina Pectoris | Atheroma; Heart

Korea, Republic of
The First Affiliated Hospital of Soochow University

Recruiting

Individualized Induction Therapy for Non-elderly Acute Myeloid Leukemia Patients With Adverse Risk Features

Acute Myeloid Leukemia, Adult

China
Memorial Sloan Kettering Cancer Center

Recruiting

Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders

Hemoglobinopathies | AML | MDS | Bone Marrow Failure | ALL | Inherited Metabolic Disorders | HLH | MPD Withou Myelofibrosis | NHL or HL

United States
Harpoon Therapeutics

Recruiting

Study in Patients With Advanced Cancers Associated With Expression of DLL3

Neuroendocrine Carcinoma | Small-Cell Lung Cancer

United States
Ascentage Pharma Group Inc.

Recruiting

A Study of APG-115 Alone or Combined With Azacitidine in Patients With AML, CMML, or MDS

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia | AML | MDS | CMML | High-risk Myelodysplastic Syndrome

United States
West China Hospital

Recruiting

Radiotherapy Versus Radiotherapy Combined With Temozolomide in High-risk Low-grade Gliomas After Surgery

Low-grade Glioma

China
Assiut University

Not yet recruiting

Effect of Rosuvastatin on the Clinical Features of Preeclampsia

Preeclampsia
Fudan University

Recruiting

Carboplatin Intensified Chemotherapy for TRIple NEgative Breast Cancer(CITRINE) (CITRINE)

Triple-negative Breast Cancer

China
Gruppo Italiano Malattie EMatologiche dell'Adulto

Recruiting

Feasibility of Allogeneic Stem Cell Transplantation in Higher-risk-MDS (ACROBAT) (ACROBAT)

High-risk MDS

Italy
University of Michigan
National Institute of Mental Health (NIMH)

Recruiting

Multi-modal Assessment of Gamma-aminobutyric Acid (GABA) Function in Psychosis (GABAmech)

Healthy | Schizophrenia | Bipolar Disorder | Psychosis | Schizo Affective Disorder | Major Depression With Psychotic Features | Schizophreniform Disorders

United States
Medical University of Silesia

Not yet recruiting

Clinical Characteristics of Interstitial Pneumonia With Autoimmune Features (IPAF) - a Multicenter Prospective Study

Autoimmune Diseases | Interstitial Lung Disease | Interstitial Pneumonia | Interstitial Fibrosis

Italy, Poland
Merck Sharp & Dohme LLC

Recruiting

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)

High-risk Non-muscle Invasive Bladder Cancer

Canada, Belgium, United States, Australia, Austria, France, Germany, Greece, Hungary, Italy, Japan, Korea, Republic of, Malaysia, Netherlands, Peru, Poland, Portugal, Spain, Switzerland, Turkey, United Kingdom, China, Brazil, Colombia, ... and more
Masonic Cancer Center, University of Minnesota

Recruiting

Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma

Neuroblastoma

United States
St. Jude Children's Research Hospital
Novartis Pharmaceuticals

Completed

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Glioma | Neoplasms | Glioblastoma | Neoplasms, Neuroepithelial | Central Nervous System Neoplasms | Brain Cancer | Brain Tumor | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Pineoblastoma | Recurrent Medulloblastoma | CNS Tumor | Pediatric... and other conditions

United States
Amgen

Completed

Phase 3 Trial of Blinatumomab vs Standard Chemotherapy in Pediatric Subjects With HIgh-Risk (HR) First Relapse B-precursor Acute Lymphoblastic Leukemia (ALL)

Leukemia, Acute Lymphoblastic

Italy, United Kingdom, Belgium, Mexico, Germany, Russian Federation, Turkey, Spain, Australia, Poland, Austria, Czechia, France, Portugal, Israel, Denmark, Brazil, Romania, Sweden, Switzerland, Norway, Netherlands, Argentina, Greece
Gustave Roussy, Cancer Campus, Grand Paris

Terminated

Study of Sequential High-dose Chemotherapy in Children With High Risk Medulloblastoma (HR MB-5)

High-risk Medulloblastoma

France
UNICANCER

Active, not recruiting

Feasibility and Tolerance of Nivolumab Neoadjuvant Immunotherapy in High Risk HPV Driven Oropharynx Cancer (IMMUNEBOOST)

Oropharynx Cancer

France
Biogen

Active, not recruiting

A Study to Assess the Potential for Gastric-pH Dependent Drug-Drug Interactions of BIIB122 With a Proton Pump Inhibitor in Healthy Participants

Healthy Volunteer

United States
University Health Network, Toronto
Princess Margaret Hospital, Canada

Active, not recruiting

Real-time Detection of ctDNA and/or HPV DNA in High-risk Locally-advanced Head and Neck Squamous Cell Carcinoma

Cancer | Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma

Canada
Geisinger Clinic
National Institute on Aging (NIA); Massachusetts Institute of Technology; National...

Completed

High-risk Influenza Vaccine Alert

Influenza

United States

Search clinical trials for: High-risk molecular features

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