Search clinical trials for: Human Anti-IL-6 Monoclonal Antibody

Total 135423 results

Stanley Jordan, MD

Active, not recruiting

Clazakizumab in Highly-HLA Sensitized Patients Awaiting Renal Transplant

Kidney Failure, Chronic | End-Stage Renal Disease | Kidney Transplant; Complications | Antibody-mediated Rejection | Kidney Transplant Failure and Rejection | Transplant;Failure,Kidney | Transplant Glomerulopathy

United States
Istituto Ortopedico Galeazzi

Completed

Evaluation of IL-6 in Synovial Fluid in Obese and Normal Weight Patients Suffering From Gonarthrosis During PTA (IL6PG)

IL-6 Concentration in the Synovial Fluid of Obese Patients is 100% Higher Than the IL-6 Concentration of the Synovial Fluid in Normal Weight Patients

Italy
Biocad

Completed

Study of the Efficacy and Safety of BCD-089 in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis (SOLAR)

Rheumatoid Arthritis

Russian Federation
University Hospital, Brest

Completed

Lymphocyte and Cytokine Disturbances in Polymyalgia Rheumatica (TENOR-IMMUNO)

Polymyalgia Rheumatica

France
Janssen Research & Development, LLC

Completed

A Study to Compare CNTO 328 (Anti-IL-6 Monoclonal Antibody) and VELCADE-Melphalan-Prednisone (VMP) With VMP Alone in Previously Untreated Multiple Myeloma Patients

Multiple Myeloma

United States, Australia, France, Spain, Israel, India, Romania, Korea, Republic of, Singapore, Russian Federation, Poland
Centre Leon Berard

Completed

Prospective Study in Patients With Advanced or Metastatic Cancer and SARS-CoV-2 Infection (IMMUNONCOVID)

SARS-CoV-2 (COVID-19) Infection | Advanced or Metastatic Hematological or Solid Tumor

France
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0354, Anti-IL-6 Chimeric Monoclonal Antibody in Patients With Metastatic Prostate Cancer That Did Not Respond to Hormone Therapy

Prostate Cancer

United States
First Affiliated Hospital of Guangxi Medical University

Completed

Monitoring of Azathioprine Metabolite Concentrations and Cytokine Levels in Neuromyelitis Optica Spectrum Disorder

NMO Spectrum Disorder | Azathioprine Adverse Reaction

China
Tourmaline Bio, Inc.

Recruiting

A Study to Evaluate TOUR006 in Patients With Chronic Kidney Disease and Elevated Hs-CRP (TRANQUILITY)

Chronic Kidney Diseases | Chronic Renal Insufficiency | Chronic Kidney Insufficiency | C-Reactive Protein | Chronic Renal Diseases | Kidney Insufficiency, Chronic | hsCRP | High Sensitivity C-Reactive Protein | Hs-CRP

United States
Medical University of Vienna
Charite University, Berlin, Germany; University of Alberta; CSL Behring

Completed

A Pilot Trial of Clazakizumab in Late ABMR

Antibody-mediated Rejection

Austria, Germany
Atsushi Kawakami
Gilead Sciences

Recruiting

Efficacy and Safety of Selective JAK 1 Inhibitor Filgotinib in Active Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate (TRANSFORM)

Rheumatoid Arthritis | Biomarker | JAK Inhibitor | Musculoskeletal Ultrasound | IL-6 Inhibitor

Japan
Riphah International University
KRL Hospital, Islamabad

Recruiting

Diagnostic and Prognostic Blood Markers in Non Specific Low Back Pain

Low Back Pain

Pakistan
Milton S. Hershey Medical Center

Withdrawn

Fluoxetine to Reduce Hospitalization From COVID-19 Infection (FloR COVID-19)

Covid19

United States
National Institute of Allergy and Infectious Diseases...
PPD; Rho Federal Systems Division, Inc.; Immune Tolerance Network (ITN)

Completed

Tocilizumab (TCZ) in New-onset Type 1 Diabetes (EXTEND)

Type 1 Diabetes Mellitus | T1DM | T1D | New-onset Type 1 Diabetes Mellitus

United States, Australia
Biocad

Active, not recruiting

A Two-Stage Study of the Efficacy, Safety, Pharmacokinetics, Pharmacodynamics and Immunogenicity of Various Doses of Levilimab When Administered Intravenously and Subcutaneously to Healthy Subjects and Subjects With Active Rheumatoid Arthritis

Rheumatoid Arthritis

Russian Federation
Cedars-Sinai Medical Center

Completed

Clazakizumab (Anti-Interleukin 6 (IL-6) Monoclonal) Compared to Placebo for Coronavirus Disease 2019 (COVID-19)

COVID-19

United States
Sohag University

Recruiting

IL6&8 in Malnourished Children With Acute Diarrhea

Acute Gastroenteritis | Severe Acute Malnutrition | Acute Diarrhea

Egypt
Sohag University

Recruiting

Evaluation of Serum Interleukin 6 and 8 in Children With Acute Gastroenteritis

Acute Gastroenteritis | Acute Diarrhea

Egypt
Marc Y.Donath

Completed

Role of Interleukin-1 in the Regulation of Muscle Derived Interleukin-6 During Exercise (MUSIL)

Type 2 Diabetes

Switzerland
Universitas Airlangga
Danone Institute International

Completed

The Effect of Lactoferrin in High Calorie Formula on IL-6 and IL10 in Children With Failure to Thrive and Infection (Interleukin)

Infections | Failure to Thrive

Indonesia
University Hospital, Montpellier

Completed

IL-6 as a Biomarker for Personalized Treatment of PR (REMISIX)

Rheumatoid Arthritis

France
Centocor Research & Development, Inc.

Completed

A Study of the Safety and Pharmacokinetics of CNTO 136 in Patients With Cutaneous Lupus Erythematosus and Systemic Lupus Erythematosus

Lupus Erythematosus, Systemic | Lupus Erythematosus, Cutaneous
Vanderbilt University Medical Center
American Heart Association

Not yet recruiting

Long COVID Immune Profiling

Long COVID | Autonomic Dysfunction | POTS - Postural Orthostatic Tachycardia Syndrome
Janssen Research & Development, LLC
GlaxoSmithKline

Completed

A Study of CNTO 136 (Sirukumab), a Human Anti-IL-6 Monoclonal Antibody, Administered Subcutaneously, in Patients With Active Rheumatoid Arthritis Despite Anti-TNF-Alpha Therapy (SIRROUND-T)

Arthritis, Rheumatoid

United States, France, Poland, United Kingdom, Germany, Taiwan, Spain, Mexico, Portugal, Korea, Republic of, Japan, Canada, New Zealand, Russian Federation, Puerto Rico, Austria, Argentina, Lithuania, Belgium, Croatia, Australia, ...
Nantes University Hospital

Recruiting

Dose-escalation of Siltuximab in Combination With Idarubicin and Cytarabine Chemotherapy in Patients With Acute Myeloblastic Leukaemia (AML) With Poor Prognosis: SILTUXILAM (SILTUXILAM)

Acute Myeloid Leukemia (AML)

France
Avidia

Unknown

Phase 1 Study of Safety and Biological Effects of C326, an Inhibitor of IL-6, in Crohn's Disease

Crohn's Disease

Australia
Case Western Reserve University

Completed

AIDS 347: IL-6 Blockade in Treated HIV Infection (IL-6)

HIV Infections

United States
Novo Nordisk A/S

Terminated

First Human Dose Study of Anti-IL-20 in Psoriasis: A Study of Safety, Tolerability and Early Signals of Biologic and Clinical Effects

Inflammation | Psoriasis

United States
Toros University

Not yet recruiting

Metabolic Control Adolescents Type 1 Diabetes

13-18 Year | Diagnosed at Least 6 Months Ago | HbA1C> 7.5 | Being Able to Read and Write
Nantes University Hospital

Completed

Monocentric Phase 1 Study With Escalation of Doses of Tocilizumab in Combination With Chemotherapy (Idarubicin and Cytarabine) in Patients With Acute Myeloblastic Leukemia (AML) (Tocilam)

Acute Myeloid Leukemia (AML)

France
Merck KGaA, Darmstadt, Germany

Completed

Multiple Ascending Dose Trial of MSB0010841 (Anti-IL17A/F Nanobody) in Psoriasis Subjects

Psoriasis

Germany
Brigham and Women's Hospital
GlaxoSmithKline

Completed

Mepolizumab As a Steroid-sparing Treatment Option in the Churg Strauss Syndrome (MATOCSS)

Churg Strauss Syndrome

United States
NHS Greater Glasgow and Clyde
University of Glasgow; NHS Ayrshire and Arran; Golden Jubilee National Hospital

Not yet recruiting

CharacterisatiON of carDiac funCTion in Intensive Care Unit Survivors of Sepsis. (CONDUCT-ICU)

Heart Failure | Sepsis | Septic Shock | Myocarditis

United Kingdom
University of Messina

Completed

Evaluation of Saliva IL-6 Levels and Periodontitis

Periodontal Diseases

Italy
Goethe University

Completed

Cytokines in Papillon-Lefèvre Syndrome

Papillon-Lefevre Disease

Germany
Janssen Pharmaceutical K.K.
GlaxoSmithKline

Completed

A Study of CNTO 136 (Sirukumab) Administered Subcutaneously in Japanese Patients With Active Rheumatoid Arthritis Unresponsive to Methotrexate or Sulfasalazine

Arthritis, Rheumatoid

Japan
Janssen Research & Development, LLC

Completed

A Study of Siltuximab (Anti- IL 6 Monoclonal Antibody) in Patients With High-risk Smoldering Multiple Myeloma

High-risk Smoldering Multiple Myeloma

United States, United Kingdom, Belgium, Germany, France, Spain, Korea, Republic of, Australia, Israel, Greece, Sweden
Dr. Soetomo General Hospital

Completed

Neuromuscular Electrical Stimulation in Chronic Heart Failure Patient

Chronic Heart Failure

Indonesia
Centre Hospitalier Universitaire de Nice

Completed

Diagnostic of Spontaneous Bacterial Peritonitis

Spontaneous Bacterial Peritonitis

France
Charite University, Berlin, Germany
German Research Foundation; adexter GmbH

Completed

Immunoadsorption of LPS, C5a and IL-6 in Severe Sepsis and Septic Shock (ISASS-1)

Septicemia

Germany
Istituto Ortopedico Galeazzi

Recruiting

Correlation Between Altered Glycometabolic Status and Joint Inflammation in Diabetic Patients With Osteoarthritis Undergoing Knee Arthroplasty (GLICO PG)

To Evaluate a Linear Positive Correlation Between Plasma HbA1c and Synovial IL-6 in Diabetic Patients

Italy
Fundació Institut de Recerca de l'Hospital de la...

Recruiting

Pharmacogenetic Studies on Anti-IL-6 Receptor Monoclonal Antibodies on the Treatment of Rheumatic Diseases

Rheumatoid Arthritis | Giant Cell Arteritis | Idiopathic Juvenile Arthritis | Still Disease

Spain
Janssen Research & Development, LLC
GlaxoSmithKline

Completed

A Study of CNTO 136 (Sirukumab), Administered Subcutaneously, in Patients With Active Rheumatoid Arthritis Despite Disease-Modifying Antirheumatic Drug (DMARD) Therapy (SIRROUND-D)

Arthritis, Rheumatoid

United States, Poland, Ukraine, Taiwan, Mexico, Bulgaria, Malaysia, Romania, Serbia, South Africa, Korea, Republic of, Japan, Canada, Russian Federation, Chile, Lithuania, Colombia, Croatia
Ferring Pharmaceuticals

Completed

A Study to Investigate Interleukin-6 (IL-6) and IL-6/Soluble IL-6 Receptor (sIL-6R) Complex Levels in Subjects With Active Inflammatory Bowel Disease

Inflammatory Bowel Disease

Denmark, Sweden
Cambridge University Hospitals NHS Foundation Trust

Unknown

Anti IL-18 (GSK1070806) in Behcet's Disease

Behcet's Disease

United Kingdom
Belfast Health and Social Care Trust
Queen's University, Belfast

Completed

Inhibition of Bradykinin in COVID-19 Infection With Icatibant (ICASARS)

SARS CoV 2 Infection

United Kingdom
First Affiliated Hospital, Sun Yat-Sen University
Wuhan University; Guangzhou First People's Hospital; Beijing Chao Yang Hospital; Zhujiang Hospital and other collaborators

Unknown

Efficacy and Safety Study of CA330 Hemoadsorption Device on IL-6 Removal in Septic Patients

Sepsis

China
China Medical University Hospital

Completed

Functional Plasticity of Human IL-17-producing CD8+ T Cells

IL-17+ CD8 T Cells in Cancer Patients

Taiwan
Hadassah Medical Organization
Sheba Medical Center; Wolfson Medical Center

Unknown

The Use of Tocilizumab in the Management of Patients Who Have Severe COVID-19 With Suspected Pulmonary Hyperinflammation

Covid19 Pneumonia

Israel
University Hospital Ostrava

Completed

Acute Kidney Injury in Severe Trauma

Acute Kidney Injury

Czechia

Search clinical trials for: Human Anti-IL-6 Monoclonal Antibody

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