Search clinical trials for: IONIS-SMN Rx

Total 507 results

Biogen

Completed

A Study for Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in Nusinersen (ISIS 396443) Investigational Studies (SHINE)

Spinal Muscular Atrophy

United States, Spain, Germany, United Kingdom, Australia, Japan, Canada, Belgium, France, Hong Kong, Italy, Korea, Republic of, Sweden, Turkey
Biogen

No longer available

Expanded Access Program (EAP) for Nusinersen in Participants With Infantile-onset (Consistent With Type 1) Spinal Muscular Atrophy (SMA)

Infantile-onset Spinal Muscular Atrophy

New Zealand, Colombia, Turkey
Biogen

Completed

An Open-label Safety, Tolerability, and Dose-range Finding Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA) (SMNRx)

Spinal Muscular Atrophy

United States
Biogen

Completed

A Study to Assess the Efficacy, Safety and Pharmacokinetics of Nusinersen (ISIS 396443) in Infants With Spinal Muscular Atrophy (SMA)

Spinal Muscular Atrophy

United States, Canada
Biogen

Terminated

A Study to Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Infants With Spinal Muscular Atrophy (ENDEAR)

Spinal Muscular Atrophy

Korea, Republic of, United States, Spain, Canada, Germany, Australia, Japan, Sweden, Belgium, France, Italy, Turkey, United Kingdom
Biogen

Completed

A Study to Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Participants With Later-onset Spinal Muscular Atrophy (SMA) (CHERISH)

Spinal Muscular Atrophy

United States, Germany, Spain, Canada, France, Hong Kong, Italy, Japan, Korea, Republic of, Sweden
Biogen

Completed

An Open-label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy Who Previously Participated in ISIS 396443-CS1 (NCT01494701)

Spinal Muscular Atrophy

United States
Biogen

Completed

An Open-label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in ISIS 396443-CS2 (NCT01703988) or ISIS 396443-CS10 (NCT01780246)

Spinal Muscular Atrophy

United States
University of Bari
Doctors with Africa - CUAMM

Not yet recruiting

Comparative Efficacy of CUS, CXR and CAD in TB Diagnosis in LMIC (CUSTB)

Tuberculosis, Pulmonary
The University of Texas Health Science Center,...
USDA The Gus Schumacher Nutrition Incentive Program (GusNIP)

Not yet recruiting

Brighter Bites/Legacy Produce Rx Program

Child Obesity

United States
The University of Texas Health Science Center,...
Brighter Bites and Humana Foundation

Not yet recruiting

Brighter Bites & University of Texas Physicians Produce Rx Extension: Evaluating the Effectiveness of a Prospective Clinical Nutrition Study With Produce Prescriptions

Obesity, Childhood

United States
Laval University

Recruiting

Unravelling the Impact of Diet on Cardiovascular Health in Treated Heterozygous Familial Hypercholesterolemia.

Familial Hypercholesterolemia | Cholesterol, Elevated | Nutrition, Healthy

Canada
Altria Client Services LLC
Celerion

Recruiting

Pharmacokinetic and Subjective Effects of Heated Tobacco Products

Tobacco Use

United States
Dosentrx Ltd.

Not yet recruiting

Open Label, Controlled, Post Marketing, Registry Study of Ribociclib (Ribo) Treatment Adherence and Patient Reported Outcomes in Participants Using ReX Technology Platform

Any Solid Oral Medication

United States
Mauro H. Schenone

Not yet recruiting

Fetal Aortic Valvuloplasty for Evolving Hypoplastic Left Heart Syndrome

Hypoplastic Left Heart Syndrome

United States
VA Office of Research and Development

Recruiting

Weight Loss and ExeRcise (EMPOWER)

Stroke

United States
AstraZeneca

Not yet recruiting

A Phase IIb Study of AZD5462 in Patients With Chronic Heart Failure (LUMINARA)

Chronic Heart Failure
The University of Texas Health Science Center,...

Not yet recruiting

Accelerating Healthcare Engagement in Healthy Food Interventions - Food Rx in High Risk Pregnant Mothers With About Fresh and Texas Children's Health Plan

Nutrition in High-Risk Pregnancy

United States
University of Washington

Recruiting

Increasing Physical Activity for Adults With Multiple Sclerosis (MS)

Fatigue | Multiple Sclerosis (MS) | Physical Inactivity

United States
Hoffmann-La Roche

Recruiting

A Study of Tiragolumab Plus Atezolizumab Compared With Placebo Plus Atezolizumab in Participants With Completely Resected Non-small Cell Lung Cancer Who Have Received Adjuvant Platinum-based Chemotherapy (SKYSCRAPER-15)

Non-small Cell Lung Cancer (NSCLC)

Korea, Republic of, United States, China, Japan, Australia, Taiwan, Brazil, Argentina, Hong Kong
VA Office of Research and Development

Recruiting

A Biomechanical Evaluation of the Ossur Power Knee in Persons With Transfemoral Amputation (OPKTFA)

Transfemoral Amputation | Limb Loss | Limb Absence

United States
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Recruiting

Post-Traumatic Knee Osteoarthritis Following Anterior Cruciate Ligament Reconstruction

Anterior Cruciate Ligament Injuries | Post-Traumatic Osteoarthritis of Knee

Belgium
University National Heart Hospital
Meril Life Sciences Pvt. Ltd.

Recruiting

Scoring-Balloon Angioplasty and Sirolimus-Eluting Balloon Angioplasty for the Treatment of Diffuse, Small Vessel Coronary Artery Disease (SCA-DEB Study) (SCA-DEB)

Coronary Artery Disease

Bulgaria
POLYSAN Scientific & Technological Pharmaceutical...

Recruiting

Comparative Study of REMAXA®, Enteric-coated Tablets and REMAXOL®, Solution for Infusions, in Intrahepatic Cholestasis

Cholestasis, Intrahepatic

Russian Federation
CinPhloro Pharma, LLC

Recruiting

Study of the Research Medicine CIN-103 in Adults With Irritable Bowel Syndrome With Predominant Diarrhea (IBS-D).

Irritable Bowel Syndrome With Diarrhea

United States
The Foundation for Orthopaedics and Regenerative...

Recruiting

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for PCOS

Polycystic Ovary Syndrome | PCOS | Polycystic Ovary Syndrome (PCOS)

Antigua and Barbuda, Greece
Shanghai Yizhong Pharmaceutical Co., Ltd.

Recruiting

Paclitaxel Polymeric Micelles for Injection Versus TPC on the Treatment of HER2-negative Metastatic Breast Cancer (MBC).

Metastatic Breast Cancer (MBC)

China
Milton S. Hershey Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

A Fruit and Vegetable Prescription Program

Diabetes Mellitus | Diabetes Complications

United States
VA Office of Research and Development

Not yet recruiting

Home-based Exercise for SMI

Serious Mental Illness

United States
Bridgewater College

Not yet recruiting

Alleviating Burden of Chronic Musculoskeletal Pain in the Emergency Department

Chronic Pain
VA Office of Research and Development
VA Connecticut Healthcare System; North Texas Veterans Healthcare System

Not yet recruiting

Assessing the Efficacy of an Acceptance-Based Digital Intervention for Veterans With Chronic Pain (VACT-CP)

Chronic Pain

United States
Augusta University

Not yet recruiting

Effects of Home Base Whole-body Vibration in Osteoarthritis. (VIBE-Rx2)

Osteo Arthritis Knee | Whole Body Vibration

United States
University of California, San Francisco
UCSF CAPS-HIV Innovative Grant; UCSF CFAR-ARI HIV Boost Award; ACC/ABC Merck...

Recruiting

Heart Failure Polypill at a Safety Net Hospital

HIV Infections | Heart Failure With Reduced Ejection Fraction

United States
Yih-Ing Hser
National Institute on Drug Abuse (NIDA); University of California, Los Angeles and other collaborators

Not yet recruiting

Extended-release Buprenorphine Compared to Sublingual Buprenorphine in Rural Settings (RXR) (RXR)

Substance-Related Disorders | Opioid-Related Disorders | Narcotic-Related Disorders

United States
Resvent Holding USA LTD
Avania; Resvent Medical Technology Co., Ltd.

Not yet recruiting

Study of the Resvent RXiBreeze™ PAP System to Treat Obstructive Sleep Apnea

Obstructive Sleep Apnea

United States
University of Alberta

Recruiting

The Effect of Pharmacist-Initiated Home Blood Pressure Monitoring on Blood Pressure Control in Women

Hypertension

Canada
University of California, San Francisco

Not yet recruiting

CirrhosisRx CDS System

Cirrhosis | Decision Support Systems, Clinical

United States
VA Office of Research and Development
Syracuse University

Not yet recruiting

Leg Stretching Using an Exoskeleton on Demand for People With Spasticity

Movement Disorders | Spinal Cord Injury | Spasticity

United States
Nagasaki University
London School of Hygiene and Tropical Medicine; Siddhi Memorial Foundation

Not yet recruiting

Effectiveness of Point-of-care Lung Ultrasound for the Management of Childhood Lower Respiratory Infections (ELUS)

Pneumonia | Bronchiolitis | LRTI | Lower Respiratory Infection

Nepal
Fox Chase Cancer Center

Recruiting

Buprenorphine for Cancer Pain

Cancer-Related Pain

United States
VA Office of Research and Development

Recruiting

Improving Prosthetic Provision in Rural Communities: Limb Scanning With Caregiver Assistance

Lower Extremity Amputation

United States
Baylor College of Medicine
University of Houston; Prairie View A&M University

Recruiting

Integrating Food Rx With Best Feeding Practices With EFNEP

Childhood Obesity | Dietary Habits | Feeding Behavior | Food Selection

United States
Implantica CE Reflux Ltd.

Recruiting

Post-Market Registry for the Evaluation of RefluxStop in GERD Treatment

Gastroesophageal Reflux Disease (GERD)

Switzerland, Germany
Shanghai Zhongshan Hospital

Not yet recruiting

Clinical Outcomes of CT-FFR Versus QFR-guided Strategy for Decision-Making in Patients With Stable Chest Pain (CONFIDENT)

Coronary Artery Disease | Angina, Stable

China
Vielight Inc.

Not yet recruiting

A Pilot Study Evaluating the Efficacy of the Vielight Neuro RX Gamma in the Treatment of Post COVID-19 Cognitive Impairment

Post COVID-19 Cognitive Impairment

United States
VA Office of Research and Development

Recruiting

Problem-Solving Training for Concussion (PST-Concussion)

Brain Concussion

United States
CinDome Pharma, Inc.

Recruiting

A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adults With Diabetic Gastroparesis

Diabetic Gastroparesis

United States
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; University of Cambridge; University of Newcastle Upon-Tyne and other collaborators

Recruiting

Pulmonary Hypertension: Intensification and Personalisation of Combination Rx (PHoenix)

Pulmonary Arterial Hypertension

United Kingdom
The Miriam Hospital
National Institute on Minority Health and Health Disparities (NIMHD)

Not yet recruiting

Optimizing an Online Behavioral Weight Loss Intervention and Novel Culturally Tailored Components for Sexual Minority Women

Obesity
VA Office of Research and Development

Not yet recruiting

Multi-speed Ergonomic Wheelchair

Spinal Cord Diseases | Spinal Cord Injuries

United States

Search clinical trials for: IONIS-SMN Rx

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