Search clinical trials for: Immune checkpoint blockade resistant tumors
Total 77018 results
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Chuangzhen ChenRecruitingRadiotherapy | Immune Checkpoint Blockade | Metastatic Extracranial Malignant Solid Neoplasm | Resistance to ImmunotherapyChina
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Vall d'Hebron Institute of OncologyBanc de Sang i TeixitsRecruiting
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Novartis PharmaceuticalsCompletedSoft Tissue Sarcoma | Small Cell Lung Cancer | Gastric Adenocarcinoma | Diffuse Large B Cell Lymphoma | Esophageal Adenocarcinoma | Ovarian Adenocarcinoma | Castration Resistant Prostate Adenocarcinoma | Advanced Well-differentiated Neuroendocrine TumorsUnited States
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National Cancer Institute (NCI)Not yet recruiting
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M.D. Anderson Cancer CenterRecruiting
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Cancer Research UKHeptares Therapeutics LimitedRecruitingSarcoma | Neoplasms | Kidney Neoplasms | Uterine Cervical Neoplasms | Stomach Neoplasms | Head and Neck Neoplasms | Lung Neoplasms | Urinary Bladder Neoplasms | Colorectal Neoplasms | Pancreatic Neoplasms | Esophageal Neoplasms | Mesothelioma, Malignant | Prostatic Neoplasms, Castration-Resistant | PheochromocytomasUnited Kingdom
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Massachusetts General HospitalWilliam M. Wood FoundationRecruiting
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Washington University School of MedicineMelanoma Research Alliance; Rising Tide FoundationNot yet recruitingMetastatic Melanoma | Advanced MelanomaUnited States
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Xencor, Inc.RecruitingColorectal Cancer | Castration-resistant Prostate Cancer | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Ovarian Cancer, Epithelial | TNBC - Triple-Negative Breast Cancer | Renal Cell Carcinoma, Clear Cell | Melanoma Excluding Uveal Melanoma | Non-small Cell Lung Cancer, Squamous or...United States
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ModernaTX, Inc.RecruitingAdvanced Solid TumorsUnited States, United Kingdom, Australia, Spain
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Abramson Cancer Center at Penn MedicineMerck Sharp & Dohme LLCRecruitingMerkel Cell CarcinomaUnited States
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Jules Bordet InstituteRecruitingMelanoma | Renal Cell Carcinoma | Breast Cancer | Head and Neck Cancer | Small Cell Lung Cancer | Hepatocellular Carcinoma | Non Small Cell Lung Cancer | Mesothelioma, Malignant | Bladder Cancer | Gastrointestinal Cancer | Merkel Cell Carcinoma | Non-melanoma Skin Cancer | MSI-H Colorectal CancerBelgium
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Memorial Sloan Kettering Cancer CenterPfizerRecruiting
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H. Lee Moffitt Cancer Center and Research InstituteRecruitingMerkel Cell Carcinoma | Cutaneous Melanoma | Cutaneous Squamous Cell CarcinomaUnited States
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ExelixisRecruitingRenal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Metastatic Castration-resistant Prostate CancerUnited States, Poland, Spain, Switzerland, Austria, Australia, Belgium, Israel, Italy, New Zealand, France, Germany, United Kingdom
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Ascendis Pharma Oncology Division A/SRecruitingAdvanced Solid Tumor | Metastatic Solid Tumor | Platinum-resistant Ovarian Cancer | Locally Advanced Solid Tumor | Post Anti-PD-1 Melanoma | 2L+ Cervical Cancer | Neoadjuvant Melanoma | Neoadjuvant Non-Small Cell Lung Cancer | Post Anti-PD-(L)1 Non-Small Cell Lung Cancer | Post Anti-PD-(L)1 Small Cell...United States, Australia, Korea, Republic of
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ExelixisRecruitingCervical Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Endometrial Cancer | Epithelial Ovarian Cancer | Metastatic Castration-resistant Prostate Cancer | Hormone Receptor-positive Breast Cancer | SCCHN | Esophageal SCC | Tissue Factor-Expressing Solid TumorsUnited States, Spain, Australia, Belgium, France, Italy, Netherlands, United Kingdom, Korea, Republic of
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National Cancer Institute (NCI)RecruitingRecurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Recurrent Platinum-Resistant Ovarian Carcinoma | Refractory Ovarian CarcinomaUnited States
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Karolinska University HospitalRecruitingMetastatic MelanomaSweden
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Italian Network for Tumor Biotherapy FoundationBristol-Myers Squibb; Astex Pharmaceuticals, Inc.Not yet recruitingMelanoma | Non Small Cell Lung CancerItaly
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Abramson Cancer Center at Penn MedicineRecruiting
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Sidney Kimmel Comprehensive Cancer Center at Johns...Bristol-Myers Squibb; National Cancer Institute (NCI)RecruitingRefractory MSI - H Solid Tumors Prior of PD-(L) 1 Therapy | MSI-H TumorsUnited States
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CellCentric Ltd.RecruitingAdvanced Solid Tumors | Metastatic Breast Cancer | Non-small Cell Lung Cancer | Metastatic Castration-Resistant Prostate CancerUnited Kingdom, United States, Netherlands, France, Spain, Sweden
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Institut Claudius RegaudRecruiting
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Taiga Biotechnologies, Inc.RecruitingStage IV Melanoma | Stage III MelanomaUnited States
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Oslo University HospitalBristol-Myers SquibbRecruitingHead and Neck Squamous Cell CarcinomaNorway
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Syntrix Biosystems, Inc.M.D. Anderson Cancer Center; National Cancer Institute (NCI); Massachusetts General... and other collaboratorsRecruitingMelanoma Stage IV | Melanoma Stage IIIUnited States
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Astellas Pharma Global Development, Inc.Merck Sharp & Dohme LLCTerminatedAdvanced Solid TumorsUnited States, Korea, Republic of, Canada, Taiwan
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National Cancer Institute (NCI)Active, not recruitingHIV Infection | Metastatic Renal Cell Carcinoma | Anatomic Stage III Breast Cancer AJCC v8 | Recurrent Ovarian Carcinoma | Metastatic Lung Non-Small Cell Carcinoma | Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic Melanoma | Recurrent Head and Neck Carcinoma | Recurrent Renal Cell Carcinoma | Advanced... and other conditionsUnited States
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National Cancer Institute (NCI)Active, not recruitingSarcoma | Metastatic Renal Cell Carcinoma | Metastatic Melanoma | Recurrent Renal Cell Carcinoma | Recurrent Melanoma | Stage IV Renal Cell Cancer AJCC v8 | Metastatic Malignant Solid Neoplasm | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Clinical Stage IV Cutaneous Melanoma... and other conditionsUnited States, Canada
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SOTIO Biotech AGMerck Sharp & Dohme LLCActive, not recruitingHepatocellular Carcinoma | Colorectal Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Castration-resistant Prostate Cancer | Cutaneous Squamous Cell CarcinomaItaly, Spain, France, Belgium, Czechia, United States, Poland, Georgia, Hungary
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI); Iovance Biotherapeutics, Inc.Active, not recruitingMalignant Solid Neoplasm | Soft Tissue Sarcoma | Recurrent Ovarian Carcinoma | Triple Negative Breast Cancer | Recurrent Osteosarcoma | Refractory Osteosarcoma | Bone Sarcoma | Giant Cell Tumor of Bone | Ovarian Carcinosarcoma | Platinum-Resistant Ovarian Carcinoma | Dedifferentiated Chondrosarcoma | Malignancy... and other conditionsUnited States
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Dana-Farber Cancer InstituteActive, not recruiting
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University of ChicagoActive, not recruitingSolid TumorUnited States
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Dana-Farber Cancer InstituteMerck Sharp & Dohme LLCActive, not recruitingGlioblastomaUnited States
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Sumitomo Pharma America, Inc.TerminatedFallopian Tube Cancer | Primary Peritoneal Cancer | Urothelial Carcinoma | Renal Cell Carcinoma (RCC) | Platinum-resistant Ovarian Cancer (PROC) | Serous Epithelial Ovarian CancerUnited States, Canada
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Istari Oncology, Inc.Active, not recruiting
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedStage IV Cutaneous Melanoma AJCC v6 and v7 | Ocular Melanoma | Stage IIIC Cutaneous Melanoma AJCC v7 | Cutaneous Melanoma | Mucosal Melanoma | Stage IIIB Cutaneous Melanoma AJCC v7 | Stage IV Uveal Melanoma AJCC v7 | Stage IIIB Uveal Melanoma AJCC v7 | Stage IIIC Uveal Melanoma AJCC v7 | Stage III Acral... and other conditionsUnited States
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Actuate Therapeutics Inc.Active, not recruitingSarcoma | Cancer | Breast Neoplasms | Neoplasm Metastasis | Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Bone Cancer | Malignant Glioma | Bone Metastases | Pancreas Cancer | Renal Cancer | Refractory Non-Hodgkin Lymphoma | Bone Neoplasm | Neoplasm, Breast | Refractory Cancer | Refractory Neoplasm | Resistant... and other conditionsUnited States, Belgium, Canada, Spain, France, Netherlands, Portugal
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The Netherlands Cancer InstituteBristol-Myers SquibbActive, not recruitingMalignant Melanoma Stage IIIUnited States, Netherlands, Australia
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TriSalus Life Sciences, Inc.Active, not recruitingMetastatic Uveal Melanoma in the LiverUnited States
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Novartis PharmaceuticalsTerminatedMelanoma | Head and Neck Cancer | Pancreatic Cancer | Urothelial Cancer | NSCLC, Non Small Cell Lung Cancer | RCC, Renal Cell Cancer | DLBCL, Diffused Large B Cell Lymphoma | MSS, Microsatellite Stable Colon Cancer | TNBC, Triple Negative Breast Cancer | mCRPC, Metastatic Castration Resistant Prostate...Belgium, Italy, Taiwan, Germany, Spain, United States, Argentina, Australia, Austria, Czechia, France, Japan, Netherlands, Switzerland, Singapore
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ExelixisActive, not recruitingA Study of XL092 as Single-Agent and Combination Therapy in Subjects With Solid Tumors (STELLAR-001)Renal Cell Carcinoma | Colorectal Cancer | Metastatic Castration-resistant Prostate Cancer | Hormone Receptor Positive Breast Carcinoma | Neoplasm MalignantUnited States, Australia, Belgium, Czechia, France, Germany, Italy, Netherlands, Spain, United Kingdom
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Atreca, Inc.TerminatedMelanoma | Breast Cancer | Hepatocellular Carcinoma | Colorectal Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Triple Negative Breast Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Urothelial Carcinoma | Acral Lentiginous Melanoma | Platinum-Resistant Fallopian... and other conditionsUnited States
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TriSalus Life Sciences, Inc.Active, not recruitingHepatocellular Carcinoma | Intrahepatic CholangiocarcinomaUnited States
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Merck Sharp & Dohme LLCActive, not recruitingProstatic NeoplasmsUnited States, Argentina, Australia, Austria, Brazil, Canada, Chile, Colombia, France, Germany, Ireland, Israel, Italy, Japan, Korea, Republic of, Netherlands, Russian Federation, Spain, Taiwan, United Kingdom, Bulgaria, Czechia, Hu... and more
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National Institute of Neurological Disorders and...Completed
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John KirkwoodBristol-Myers SquibbActive, not recruiting
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ExelixisActive, not recruitingRenal Cell Carcinoma | Head and Neck Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Triple Negative Breast Cancer | Endometrial Cancer | Castration-resistant Prostate Cancer | Urothelial Carcinoma | Differentiated Thyroid Cancer | Gastroesophageal... and other conditionsUnited States, Australia, Belgium, France, Germany, Italy, Netherlands, Spain, United Kingdom
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Targovax OyAgenus Inc.Withdrawn