Search clinical trials for: Immune microenvironment

Total 57953 results

Presage Biosciences
AstraZeneca

Recruiting

PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, and Sabestomig in HNSCC

Head and Neck Squamous Cell Carcinoma

United States
Fujian Medical University Union Hospital

Recruiting

Single-cell Sequencing Analysis of Resectable/Borderline Resectable Pancreatic Cancer Patients

Pancreatic Neoplasms

China
Pure Biologics S.A.
Presage Biosciences

Recruiting

A Study of the Intratumoral Microdose Administration of PBA-0405 in Patients With Solid Tumors

Triple Negative Breast Cancer | Head and Neck Squamous Cell Carcinoma | Soft Tissue Sarcoma Adult

United States
Chinese PLA General Hospital

Recruiting

Tumor Microenvironment in Gastric Cancer Patients Treated With Combined Immunotherapy and Chemotherapy

Gastric Cancer | Chemotherapy | Immunotherapy | Tumor Microenvironment

China
Centro di Riferimento Oncologico - Aviano

Recruiting

Study for Validation of Target Therapy in Multiple Myeloma Cells From Patients With miRNAs Released From B Cells, and Study of the Bone Marrow Tumor Microenvironment (Microenvironment of MM)

Multiple Myeloma

Italy
Hospices Civils de Lyon

Recruiting

Characterization of the Intrahepatic Inflammatory Microenvironment in Patients With Non-alcoholic Steatohepatitis (Profil-NASH)

Liver Diseases

France
Institut du Cancer de Montpellier - Val d'Aurelle

Recruiting

Precision Imaging for Early Detection and Targeted Treatment Monitoring in Pancreatic Cancer (PANC-O-MICS)

Pancreas Cancer

France
Institut du Cancer de Montpellier - Val d'Aurelle

Recruiting

Unravelling Tumour Biology In Ovarian Cancer With Precision Imaging (MR-O-MICS)

High Grade Serous Ovarian Cancer

France
Ruijin Hospital

Not yet recruiting

Tumor Microenvironment Mechanism of LY007 for r/r B-NHL and the Exploration of Novel CAR-T Translational Research

Relapsed Non-Hodgkin Lymphoma
The Christie NHS Foundation Trust

Not yet recruiting

Assessing the Relationship Between Hypoxia and the Immune Environment in Myeloma Patients (CHIME) (CHIME)

Myeloma

United Kingdom
Ryan Stephenson

Recruiting

Naltrexone and Propranolol Combined With Immunotherapy

Advanced Melanoma

United States
Institut Paoli-Calmettes

Recruiting

Test of CD47-SIRPα Inhibitors on the Immune Microenvironment Colon Cancer (MACROSWITCH)

Cancer of the Colon

France
Lan Coffman
National Cancer Institute (NCI); MorphoSys AG

Recruiting

CPI-0209 Plus Carboplatin in Patients With Platinum Sensitive Recurrent Ovarian Cancer

Recurrent Ovarian Cancer

United States
China Medical University Hospital

Recruiting

The Role of Vitamin D in Corneal Epithelial Barrier Function, Ocular Microbiome, Ocular Inflammation, and Visual Acuity of Children With Allergic Conjunctivitis

Allergic Conjunctivitis

Taiwan
Assistance Publique - Hôpitaux de Paris
Gustave Roussy, Cancer Campus, Grand Paris; Paris Brain Institute

Not yet recruiting

Role of the Tumor Microenvironment in Aggressive Meningiomas (MEME)

Meningioma
University Hospital, Tours

Recruiting

Study of the Medullary Microenvironment in Acute Childhood Leukemia (MILA)

Acute Lymphoid Leukemia | Acute Myeloid Leukemia in Children

France
Peking University

Not yet recruiting

Development of Multi-specific Antibodies Based on Immune Microenvironment of Breast Cancer

Invasive Breast Cancer

China
Fubing Wang

Recruiting

Single-cell RNA Sequencing Resolves the Regulatory Role of HBV on the Hepatocellular Carcinoma Immune Microenvironment

Primary Liver Cancer | HBV

China
Centre Leon Berard

Recruiting

GastrOesophageal Tumor, Immune Microenvionnment (GOTIM) (GOTIM)

GastroEsophageal Cancer

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Physiopathology of Prosthetic Joint Infections (PROTHEE-PILOTE)

Prosthetic-joint Infection

France
Henan Provincial People's Hospital

Not yet recruiting

Correlation Between Psychological Stress and Disease Progression in Newly Diagnosed Glioblastoma Patients

Glioblastoma

China
Peking Union Medical College Hospital

Not yet recruiting

TIME in Immunotherapy Combined With nCRT for Rectal Cancer (TIMENT-R)

Locally Advanced Rectal Cancer
D'Or Institute for Research and Education
HalioDx; Diagnosticos da America SA

Recruiting

Role of Immunoscore® in Stage II-III Colorectal Cancer

Colon Adenocarcinoma

Brazil
Abramson Cancer Center at Penn Medicine

Recruiting

Role of the Immune Environment in Response to Therapy in Breast Cancer

Breast Cancer | HER2-negative Breast Cancer | TNBC - Triple-Negative Breast Cancer | ER Positive Breast Cancer

United States
Peking University People's Hospital
Research Unit of Intelligence Diagnosis and treatment of early-stage non-small...

Not yet recruiting

Multiomics Tumor Evolution Model of NSCLC

Non-small Cell Lung Cancer

China
Sichuan Cancer Hospital and Research Institute

Recruiting

Exploration of Immunodynamic Monitoring in the Population Evaluation of Neoadjuvant Chemotherapy Immunotherapy in Patients With Solid Tumors of the Chest.

Non-small Cell Lung Cancer | Esophageal Squamous Cell Carcinoma

China
University Hospital, Grenoble

Recruiting

Tumor Immune Microenvironment Involvement in Colorectal Cancer Chemoresistance Mechanisms (CRC-ORGA2)

Primary Tumor | Colon Tumor

France
Case Comprehensive Cancer Center

Recruiting

Alteration of the Immune Microenvironment in Basal Cell Carcinoma Following Photodynamic Therapy

Basal Cell Carcinoma

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Assessing the Tolerance and Clinical Benefit of feCAl tranSplantation in patientS With melanOma (PICASSO)

Melanoma

France
Tae Won Kim

Recruiting

DYNAmic Immune Microenvironment of HCC Treated With atezolIzumab Plus bevaCizumab (DYNAMIC)

Hepatocellular Carcinoma

Korea, Republic of
University of Padova
Azienda Ospedaliera di Padova; Istituto Oncologico Veneto IRCCS; Azienda Ulss... and other collaborators

Recruiting

IMMUNOlogical Microenvironment in REctal Adenocarcinoma Treatment. (IMMUNOREACT2)

Rectal Cancer

Italy
Lund University Hospital

Recruiting

Predictive and Prognostic Biomarkers in Patients With Mycosis Fungoides and Sézary Syndrome. (BIO-MUSE)

Mycosis Fungoides | Sezary Syndrome

Sweden
Universidade Nova de Lisboa
Fundação para a Ciência e a Tecnologia; Hospital Cuf Descobertas

Recruiting

Immune- and Microenvironment- Proteogenomics Profiling for Classifying Lung Cancer Patients

Lung Cancer | Malignancy

Portugal
Paolo Ghia

Not yet recruiting

Lymph Node Microenvironment Modifications in Patients With CLL Treated With Venetoclax-based Regimens (LymBIO)

Chronic Lymphocytic Leukemia
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Microenvironment and Immunity of Digestive Cancers - East Paris Multicentric Cohort (MICADO)

Colorectal Cancer | Immune System and Related Disorders | Biliary Tract Tumor | Pancreas Tumor
Yana Najjar

Recruiting

Evolution of Metabolic and Immune Dysfunction in In-transit Melanoma

Melanoma

United States
IRCCS San Raffaele
Università Vita-Salute San Raffaele

Recruiting

Advanced Therapies for Liver Metastases (LiMeT)

Liver Metastasis | Pancreatic Ductal Adenocarcinoma (PDAC) | Colorectal Cancer (CRC)

Italy
Mural Oncology, Inc

Recruiting

Less Frequent IV Dosing & Tumor Microenvironment (TME) Study of Nemvaleukin Alfa (ALKS 4230) Monotherapy and in Combination With Pembrolizumab (ARTISTRY-3) (ARTISTRY-3)

Advanced Solid Tumor

United States, Spain
Presage Biosciences
Merck Sharp & Dohme LLC

Recruiting

Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies

Solid Tumor

United States
Shenzhen Geno-Immune Medical Institute
The Seventh Affiliated Hospital of Sun Yat-sen University; Shenzhen Children... and other collaborators

Recruiting

PSMA-specific CAR-T Cell Therapy

PSMA Positive Tumors or Tumor Tissues

China
University of Erlangen-Nürnberg Medical School
Wuerzburg University Hospital; University Hospital Regensburg

Recruiting

Preconditioning of Tumor, Tumor Microenvironment and the Immune System to Immunotherapy (PROMIT)

Immunotherapy

Germany
Centre Leon Berard

Recruiting

COLON-IM : Microbiota and Immune Infiltrate in Normal, Dysplastic and Neoplastic Colorectal Tissue

Colorectal Cancer

France
Sidney Kimmel Comprehensive Cancer Center at Johns...
Merck Sharp & Dohme LLC; Verastem, Inc.

Recruiting

Study of Pembrolizumab With or Without Defactinib Following Chemotherapy as a Neoadjuvant and Adjuvant Treatment for Resectable Pancreatic Ductal Adenocarcinoma

Pancreatic Ductal Adenocarcinoma | Resectable Pancreatic Ductal Adenocarcinoma (PDAC)

United States
Institut Curie

Recruiting

Prospective Biobanking Study in Ovarian, Breast, Head and Neck and Cervical Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself, Its Microenvironment and Immune Response (SCANDARE) (SCANDARE)

Cervical Cancer | Head and Neck Cancer | Ovarian Cancer | Triple-Negative Breast Cancer

France
Eileen Connolly
Merck Sharp & Dohme LLC

Recruiting

Effects of MK-3475 (Pembrolizumab) on the Breast Tumor Microenvironment in Triple Negative Breast Cancer (Pembro/IORT)

Triple Negative Breast Cancer

United States
Presage Biosciences
Merck Sharp & Dohme LLC

Completed

PBI-MST-01 (NCT04541108) Substudy MSD-03: Intratumoral Microdosing of Pembrolizumab Alone and With MK-0482 or MK-4830 in HNSCC or STS

Soft Tissue Sarcoma | Head and Neck Squamous Cell Carcinoma

United States
Hetian District People's Hospital

Withdrawn

Effect of Low-dose Radiotherapy on Tumor Immune Microenvironment in Oligometastases of NSCLC After Immunotherapy

Non-Small Cell Lung Cancer | Low-dose Radiotherapy | Tumor Microenvironment

China
Abramson Cancer Center at Penn Medicine

Terminated

A Pilot Study of Perioperative Nivolumab and Paricalcitol to Target the Microenvironment in Resectable Pancreatic Cancer

Pancreatic Cancer

United States
Dan Zandberg
Bristol-Myers Squibb

Active, not recruiting

Personalized Immunotherapy in Patients With Recurrent /Metastatic SCCHN That Have Progressed on Prior Immunotherapy

Squamous Cell Carcinoma of the Head and Neck

United States
Institut Bergonié

Active, not recruiting

Integrative Analysis of Tumor Microenvironment and Optimization of Immunotherapy Duration in NSCL Cancer Patients (OPTIMUNELUNG)

Non Small Cell Lung Cancer

France

Search clinical trials for: Immune microenvironment

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