Search clinical trials for: Immune reconstitution

Total 57834 results

Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Using the Composite Immune Risk Score to Assess and Modulate the Patient's Post-transplant Immune Reconstitution.

Transplant-Related Disorder

China
Sichuan University

Not yet recruiting

Immune Reconstitution After Allo-HSCT and Blinatumomab

Leukemia, Lymphoid
Yao Liu

Recruiting

Efficacy and Safety of PEG-rhG-CSF Injection for Neutrophil Reconstitution Following AHSCT in Lymphoma/Multiple Myeloma

Lymphoma | Multiple Myeloma

China
Shandong Qilu Cell Therapy Engineering Technology...
Shandong Public Health Clinical Center

Recruiting

Mesenchymal Stem Cells for Immune Non-responder Patients With HIV Infection

AIDS Virus | Disorder of Immune Reconstitution

China
University of Ulm

Recruiting

Immune Modulation by Exosomes in COVID-19 (IMECOV19)

COVID-19 | Critical Illness | Lung Fibrosis | Hypercytokinemia

Germany
Tehran University of Medical Sciences

Recruiting

Effectiveness of COVID-19 Vaccine in Hematopoietic Stem Cell Transplant Patients (ESCVHSCT)

COVID-19 Vaccines | Hematopoietic Stem Cell Transplantation (HSCT) | Immune System Tolerance

Iran, Islamic Republic of
Federal Research Institute of Pediatric Hematology...

Recruiting

Ex-vivo Primed Memory Donor Lymphocyte Infusion to Boost Anti-viral Immunity After T-cell Depleted HSCT

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia, in Relapse | Non-hodgkin Lymphoma | High Risk Acute Myeloid Leukemia | High Risk Acute Lymphoblastic Leukemia | Acute Biphenotypic Leukemia in Relapse

Russian Federation
National Institute of Neurological Disorders and...
NeoImmuneTech

Recruiting

NT-I7, a Long-Acting Recombinant IL-7 Molecule, as an Immune Reconstitution Strategy for Lymphopenia in Patients With Progressive Multifocal Leukoencephalopathy

Progressive Multifocal Leukoencephalopathy

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Study Evaluating the Safety and the Efficacy of Human T Lymphoid Progenitor (HTLP) Injection to Accelerate Immune Reconstitution After Umbilical Cord Blood (UCB) Transplantation in Adult Patients With Hematologic Malignancies (HTLP-ONCO) (HTLP-ONCO)

Hematologic Malignancy

France
Neuromed IRCCS

Recruiting

Role of ADA SNPs in Subjects With Relapsing Multiple Sclerosis (RMS)

Relapsing Multiple Sclerosis

Italy
National Institute of Allergy and Infectious Diseases...

Recruiting

Paradoxical Tuberculosis Reactions in Patients Without HIV Infection

Tuberculosis

United States
European Society for Blood and Marrow Transplantation

Recruiting

EBMT ADWP Prospective Non-interventional Study: Post-AHSCT Management in SSC Patients (NISSC-2) (NISSC-2)

Autoimmune Diseases

France
Guangzhou 8th People's Hospital
Sun Yat-sen University

Recruiting

The Effect of Chimeric Antigen Receptor (CAR)-T Cell Therapy on the Reconstitution of HIV-specific Immune Function

HIV/AIDS

China
National Institute of Allergy and Infectious Diseases...

Recruiting

PET Imaging and Lymph Node Assessment of IRIS in People With AIDS

Immune Reconstitution Inflammatory Syndrome

United States
University of Miami

Recruiting

Immune Reconstitution in Stem Cell Transplant Recipients

Cancer

United States
National Institute of Neurological Disorders and...

Recruiting

Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)

Progressive Multifocal Leukoencephalopathy

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)

X-linked Severe Combined Immunodeficiency (XSCID)

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

TAC/MTX vs. TAC/MMF/PTCY for Prevention of Graft-versus-Host Disease and Microbiome and Immune Reconstitution Study (BMT CTN 1703/1801) (1703/1801)

Lymphoma | Acute Leukemia | Myelodysplasia | Chronic Myelogenous Leukemia (CML)

United States
University Hospital, Basel, Switzerland
London School of Hygiene and Tropical Medicine; Swiss National Science Foundation and other collaborators

Active, not recruiting

Same-day Versus Rapid ART Initiation in HIV-positive Individuals Presenting With Symptoms of Tuberculosis (SaDAPT)

Human Immunodeficiency Virus (HIV) Infection

Lesotho, Malawi
Peking University People's Hospital

Enrolling by invitation

Immune Reconstitution to CMV After HSCT: Impact of Clinical Factors and Therapy Strategies

Hematopoietic Stem Cell Transplantation | CMV Infection

China
Michael Pulsipher, MD

Active, not recruiting

Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation (ACES)

Cytomegalovirus Infections | EBV Infection | Adenovirus Infection

United States
Duke University

Suspended

Reconstitution of a Human Immune System in a Patient Derived Xenograft (PDX) Model of Genitourinary (GU) Cancers (Immune PDX)

Kidney Cancer | Prostate Cancer | Bladder Cancer | Genito Urinary Cancer

United States
Biogen

Completed

Real World Analysis on Lymphocyte Reconstitution After Lymphopenia in Participants Treated by Tecfidera (Lympho-TEC)

Multiple Sclerosis | Multiple Sclerosis, Relapsing-Remitting

France
Masonic Cancer Center, University of Minnesota

Terminated

Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies

Cytokine Release Syndrome | Immune and Microbial Reconstitution | Systemic Viral Infection | Acute-graft-versus-host Disease | Chronic Graft-versus-host-disease | Recurrent Malignancy | Allogenic Related Donors | Cell Therapy/Immunotherapy Patients

United States
Shanghai Public Health Clinical Center

Completed

Zadaxin and HIV-positive Patients With Immune Reconstitution Disorder

HIV-1-infection

China
Rush University Medical Center
Gilead Sciences; University of Chicago; University of Illinois at Chicago; Abbott; Ruth M. Rothstein CORE Center

Terminated

Immune Reconstitution of Lopinavir/Ritonavir-Based vs Efavirenz-based HAART in Advanced HIV Disease

Acquired Immune Deficiency Syndrome

United States
University of Cincinnati
Gilead Sciences; Abbott

Completed

Immune Reconstitution as a Determinant of Adverse Effects to New Antiretroviral Therapy in Persons With Advanced HIV Infection

HIV Infections

United States
Kiadis Pharma

Terminated

Safety and Efficacy of ATIR101 as Adjunctive Treatment to Blood Stem Cell Transplantation From a Haploidentical Family Donor Compared to Post-transplant Cyclophosphamide in Patients With Blood Cancer (HATCY)

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States, Canada, Netherlands, Israel, Germany, United Kingdom, Belgium, Italy, Sweden, Croatia, Spain, France, Portugal
National Institute of Cancerología
Instituto Nacional de Enfermedades Respiratorias

Completed

Impact of Valganciclovir on Severe IRIS-Kaposi Sarcoma Mortality: an Open-label, Parallel, Randomized Controlled-trial.

Kaposi Sarcoma | Human Immunodeficiency Virus | Immune Reconstitution Syndrome

Mexico
Friedemann Paul
Beuth Hochschule für Technik Berlin; NovaVision AG, Zentrum für Sehtherapie

Completed

Visual Reconstitution Therapy After Optic Neuritis (VISION)

Multiple Sclerosis | Optic Neuritis

Germany
Kiadis Pharma

Terminated

Efficacy and Safety of a Donor Lymphocyte Preparation Depleted of Functional Host Alloreactive T-cells (ATIR) in Patients Undergoing a Peripheral Blood Stem Cell Transplant From a Related, Haploidentical Donor

Lymphoma | Myeloid Leukemia | Myeloproliferative Disorders | Multiple Myeloma | Myelodysplastic Syndrome | Lymphoblastic Leukemia

Canada, Netherlands, Germany, Belgium, United States, Italy, United Kingdom
Kiadis Pharma

Completed

Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

Canada, Belgium, Germany, Croatia, United Kingdom, Portugal
Kiadis Pharma

Completed

Safety and Efficacy of Donor T-lymphocytes Depleted ex Vivo of Host Alloreactive T-cells (ATIR) in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

Canada, Germany, Belgium, United Kingdom
Indiana University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Bridging Pediatric and Adult Biomarkers in Graft-Versus-Host Disease

Graft-Versus-Host Disease

United States
University of Minnesota
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp...

Completed

Reversing Tissue Fibrosis to Improve Immune Reconstitution in HIV

HIV Infections | HIV Infection

United States
Tarix Pharmaceuticals
Constant Therapeutics LLC

Terminated

TXA127 in Enhancement of Engraftment in Adult Double Cord Blood Transplantation (USBTXA127CBT)

Myelofibrosis | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Chronic Myelocytic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Hodgkins Lymphoma | Non Hodgkins Lymphoma | Double Cord Blood Transplant

United States
Revimmune
Washington University School of Medicine; Vanderbilt University School of Medicine

Completed

A Study of IL-7 to Restore Absolute Lymphocyte Counts in Sepsis Patients (IRIS-7-B)

Severe Sepsis With Septic Shock

United States
University of California, Davis

Completed

Mechanisms of Immune Reconstitution & Reduced Immune Activation Following Darunavir-based ART

Human Immunodeficiency Virus Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

Immune Reconstitution Syndrome in HIV-Infected Patients Taking Antiretroviral Therapy

Immune Reconstitution Inflammatory Syndrome

United States, Thailand
Beijing 302 Hospital

Unknown

Safety and Efficacy of Allogenic Adoptive Immune Therapy for Immune Reconstitution in Chronic HIV-1 Infected Patients

Human Immunodeficiency Virus | Disorder of Immune Reconstitution

China
Guangzhou 8th People's Hospital
Sun Yat-sen University

Completed

Reconstitution of HIV-specific Immunity Against HIV

HIV

China
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Do CCR5 Antagonists Improve the Overall Survival of Patients With AIDS-related Progressive Multifocal Leucoencephalopathy?

AIDS | Progressive Multifocal Leucoencephalopathy (PML)
Cambridge University Hospitals NHS Foundation Trust

Terminated

Keratinocyte Growth Factor to Prevent Autoimmunity After Alemtuzumab Treatment of Multiple Sclerosis (CAM-THY)

Multiple Sclerosis

United Kingdom
Central Hospital, Nancy, France

Unknown

Dysbiosis and Immune Reconstitution After Allo-HSCT (PARI-DYS)

Hematopoietic Stem Cell Transplantation

France
Gilead Sciences

Terminated

Efficacy and Tolerability of Entospletinib in Combination With Systemic Corticosteroids as First-Line Therapy in Adults With Chronic Graft Versus Host Disease (cGVHD)

Chronic Graft Versus Host Disease

Spain, Korea, Republic of, United States, Germany, Canada, France, United Kingdom
University Hospital of Ferrara

Completed

Reconstitution of CD4+CD25highCD127low/-Tcell

Rheumatoid Arthritis
National Institute of Allergy and Infectious Diseases...

Terminated

Gene Therapy for Chronic Granulomatous Disease

Chronic Granulomatous Disease

United States
Emory University

Completed

Bone Loss and Immune Reconstitution in HIV/AIDS (BLIR-HIV) (BLIR-HIV)

HIV Infection | Osteoporosis | Bone Loss | Osteopenia

United States
University of Washington
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pediatric Urgent Start of Highly Active Antiretroviral Treatment (HAART) (PUSH)

Human Immunodeficiency Virus | Immune Reconstitution Inflammatory Syndrome

Kenya
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France; Institut... and other collaborators

Completed

Hepatosplenic CANdidiasis : PETscan and Immune Response Analysis (CANHPARI)

Neutropenia | Hematopoietic Stem Cell Transplantation | Hematological Malignancies | Invasive Fungal Disease | Chronic Disseminated Candidiasis

France

Search clinical trials for: Immune reconstitution

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