Search clinical trials for: Immunomodulatory Drugs (IMiDs)

Total 256083 results

The First Affiliated Hospital of Soochow University

Recruiting

Study of T Cells Targeting CD19/BCMA (CART-19/BCMA) for High Risk Multiple Myeloma Followed With Auto-HSCT

Safety and Efficacy

China
University Hospital, Grenoble
Celgene Corporation

Unknown

Evaluation of the Use of Apixaban in Prevnetion of Thromboembolic Disease in Patients With Myeloma Trated With iMiDs (MYELAXAT)

Venous Thromboembolism | Myeloma

France
Fondazione EMN Italy Onlus

Completed

Revlimid And Prednisone Followed By Revlimid, Melphalan And Prednisone In Multiple Myeloma Patients (RP_MPR)

Multiple Myeloma
National Cancer Institute (NCI)

Active, not recruiting

Romidepsin, CC-486 (5-azacitidine), Dexamethasone, and Lenalidomide (RAdR) for Relapsed/Refractory T-cell Malignancies

Cutaneous T-Cell Lymphoma | Peripheral T-Cell Lymphoma | Mature T-cell Malignancies | Relapsed/ Refractory T-cell Malignancies

United States
Instituto de Investigación Marqués de Valdecilla
Puerta de Hierro University Hospital; Hospital Universitario La Fe

Unknown

Immunomediated Non-alcoholic SteaTohepatitis; Prevalence and Characterization. INSTInCT Study (INSTInCT)

Main Hypothesis is That in the NASH Associated to IMIDs, to Different Phenotypes co Exist

Spain
Instituto de Investigacion Sanitaria La Fe
Bristol-Myers Squibb

Terminated

Prophylaxis With Apixaban in Transplant Eligible Patients With Multiple Myeloma Receiving Induction Therapy With IMiDs

Venous Thromboembolism

Spain
Beijing Tongren Hospital

Unknown

Lenalidomide and Sintilimab for Relapsed/Refractory NK/T-cell Lymphoma

NK/T Cell Lymphoma Nos

China
University Hospital, Lille
FHU IMMINeNT; FHU PRECISE: Projet Fédératif Hospitalo-Universitaire PREcision... and other collaborators

Recruiting

Deployment o the Multidisciplinary Prospective Cohort Imminent (IMMINeNT)

Multiple Sclerosis | Systemic Sclerosis | Atopic Dermatitis | Psoriatic Arthritis | Angioedema | Severe Asthma | Behçet Disease | Lupus | Chronic Inflammatory Disease

France
Onward Therapeutics

Recruiting

First-in-human Study of OT-A201 in Patients With Selected Hematological Malignancies and Solid Tumors

Solid Tumor | Hematological Malignancy

France
Celgene

Completed

A Phase II Study of Pomalidomide in Myelofibrosis With Myeloid Metaplasia

Myelofibrosis | Myeloid Metaplasia | Myelofibrosis With Myeloid Metaplasia

United States, Italy, United Kingdom, Austria, Spain
Institute of Hematology & Blood Diseases Hospital

Unknown

a Clinical Trial of Efficacy and Safety of the Holistic Treatment of Young High-risk Multiple Myeloma Patients

Multiple Myeloma | Plasma Cell Leukemia | Extramedullary Plasmacytoma | Loss of Chromosome 17p | t(14;16) | t(4;14) | Complex Karyotype | T(14;20) | 1Q21 Amplification

China
Ain Shams University

Recruiting

Assessment Of Dose-Dependent Immunomodulatory Effect Of Alveofact With or Without Steroisd In Neonatal RDS

Inflammatory Response | Preterm Birth | Premature Lungs | Neonatal Respiratory Distress Syndrome | Neutrophil Extracellular Trap Formation

Egypt
University Hospital, Bordeaux

Not yet recruiting

Evaluation of the Efficacy of Immunomodulatory Therapy in Case of Psychiatric Disorders With Proven Dysimmunity. (TIM-DePisT)

Mental Disorder

France
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Interferon Alfa Therapy Based on Th17 Profile in Membranous Nephropathy (ALPHAGEM)

Membranous Nephropathy

France
Cheng LuFeng,Principal Investigator
First Affiliated Hospital of Xinjiang Medical University

Not yet recruiting

Clinical Study on the Immunomodulatory Effect of Eprolidone on Patients With Chronic Heart Failure

Chronic Heart Failure Patients
Fudan University

Recruiting

Famitinib in Combination With Camrelizumab and TPC in The First-line Treatment of Immunomodulatory Locally Advanced or Metastatic TNBC.

Triple-Negative Breast Cancer

China
Massachusetts General Hospital

Recruiting

Immunomodulatory Effects of PCSK9 Inhibition (INSPIRAR)

Heart Diseases | Cardiovascular Diseases | Vascular Diseases | Stroke | Atherosclerosis | Transient Ischemic Attack | Carotid Artery Diseases | Carotid Atherosclerosis | Cerebrovascular Accident | Atherosclerotic Cardiovascular Disease | Vascular Calcification | Heart Attack | Vascular Disease, Peripheral | Arterial... and other conditions

United States
Lucie Heinzerling

Recruiting

Treatment of Immune-related Adverse Events Refractory to Standard Therapy and Associated Changes in Immunophenotype (PRIA)

Immune-related Adverse Event

Germany
Region Örebro County

Recruiting

A Randomized Controlled Trial With Rituximab for Psychotic Disorder in Adults (RCT-RITS)

Schizophrenia Spectrum and Other Psychotic Disorders

Sweden
Angelica Lindén Hirschberg

Recruiting

Immunomodulatory Therapy in Women With Autoimmune Premature Ovarian Insufficiency

Autoimmune Diseases | Premature Ovarian Insufficiency

Sweden
Universidade Federal do Rio de Janeiro

Recruiting

Immunomodulatory Effect of Dexmedetomidine as an Adjuvant Drug in Laparoscopic Cholecystectomies

Physiological Effects of Drugs

Brazil
Centre Hospitalier St Anne
For Drug Consulting

Recruiting

Therapeutic Evaluation of Low-dose IL-2-based Immunomodulatory Approach in Patients With Early AD (IL-2-AD)

Alzheimer Disease

France
Biopharma Plasma LLC

Recruiting

Intravenous Immunoglobulin (IVIG, Bioven) Efficacy and Safety in Chronic Primary Immune Thrombocytopenia (ITP) in Adults

Primary Immune Thrombocytopenia

Ukraine
National Cancer Institute (NCI)

Recruiting

Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated Lymphomas

Burkitt Lymphoma | Plasmablastic Lymphoma | Non-Hodgkin Lymphoma | Diffuse Large Cell Lymphoma | B-Cell Neoplasm

United States
H. Lee Moffitt Cancer Center and Research Institute
Adaptive Biotechnologies

Recruiting

Multiple Myeloma Outcomes Based on Maintenance Therapy Post Autologous Stem Cell Transplant

Multiple Myeloma

United States
Sun Yat-sen University

Recruiting

Corticosteroid Combining Noncorticosteroid Systemic Immunomodulatory Therapy in VKH

Vogt Koyanagi Harada Disease (VKH)

China
Alpha Tau Medical LTD.

Recruiting

A Safety and Efficacy Study for Combinational Treatment of DaRT and Check Point Inhibitor for Recurrent Unresectable or mHNSCC

Skin Cancer | Head and Neck Squamous Cell Carcinoma | Metastatic Head-and-neck Squamous-cell Carcinoma

Israel
Phoenicis Therapeutics

Recruiting

Trial to Determine the Immunomodulatory Activity of PTM-001 in Patients With Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States
National Cancer Institute (NCI)
Janssen Scientific Affairs, LLC

Recruiting

Subcutaneous Daratumumab, Once Weekly Carfilzomib, and Dexamethasone (DKd) in Patients With High-Risk Smoldering Multiple Myeloma

Multiple Myeloma

United States
Alexandria University

Recruiting

Immunomodulatory Effects of Dexmedetomidine Infusion

Major Abdominal Surgery

Egypt
University of Crete
University Hospital of Crete

Recruiting

Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair

Postoperative Pain | Anesthesia | Opioid Use | Interleukin 6 | Elective Surgical Procedures | Abdominal Aortic Aneurysm Without Rupture | Vascular Surgical Procedure | Immunomodulators

Greece
Assistance Publique - Hôpitaux de Paris
URC-CIC Paris Descartes Necker Cochin; MICALIS Institute

Recruiting

Use of Crohn's Disease Exclusion Diet on Top of Standard Therapy Versus Standard Therapy Alone in Unstable Pediatric Crohn's Disease Patients. (ASCENSION)

Crohn's Disease

France
Assistance Publique - Hôpitaux de Paris

Recruiting

Immunomodulatory Profile of Dexmedetomidine Sedation in Patients Recovering After ARDS Covid-19 (DEXDO-COVID)

SARS-CoV 2

France
Janssen Biotech, Inc.

Active, not recruiting

A Multicenter, Prospective, Long-term, Observational Registry of Pediatric Patients With Inflammatory Bowel Disease (DEVELOP)

Inflammatory Bowel Diseases | Crohn's Disease | Ulcerative Colitis | Indeterminate Colitis

United States, Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Cryoablation for the Treatment of Metastatic Cancer

Metastatic Malignant Neoplasm

United States
Lin Chen

Completed

Esmolol in Sepsis Management:Evaluating Immunomodulatory Effects and Impact on Patient Outcomes

Sepsis | Cytokine Storm | Sympathetic Nervous System Diseases | Catecholamine; Overproduction | Immunologic Paralysis | Lymphocyte Disorder T | Beta-Blocker

China
National Cancer Institute (NCI)

Active, not recruiting

Carfilzomib, Lenalidomide, and Dexamethasone for Smoldering Multiple Myeloma

Multiple Myeloma

United States
Bristol-Myers Squibb

Active, not recruiting

Incidence of Hyperpigmentation in Black Patients With Multiple Myeloma Treated With Immunomodulatory Drugs

Multiple Myeloma

United States
Janssen Research & Development, LLC

Completed

A Study of JNJ-54767414 (HuMax CD38) (Anti-CD38 Monoclonal Antibody) in Combination With Backbone Treatments for the Treatment of Patients With Multiple Myeloma

Multiple Myeloma

United States, France, Spain
Amgen

Completed

Efficacy and Safety of AMG 570 in Subjects With Active Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus (SLE)

United States, Korea, Republic of, Australia, Spain, Hungary, Bulgaria, Italy, Mexico, Germany, Japan, France, Greece, Czechia, Argentina, Portugal, Poland, Russian Federation, Hong Kong, Canada
Pfizer

Completed

PF-06863135 As Single Agent And In Combination With Immunomodulatory Agents In Relapse/Refractory Multiple Myeloma

Multiple Myeloma

Canada, United States
Mayo Clinic

Active, not recruiting

Immunomodulatory Drugs (Lenalidomide With or Without Pomalidomide) in Combination With a Corticosteroid Drug (Dexamethasone) for the Treatment of Multiple Myeloma

Plasma Cell Myeloma | Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma | Smoldering Plasma Cell Myeloma

United States
Calla IVF Center

Completed

Effect of Immunomodulatory Treatment on IVF (in Vitro Fertilization) Outcomes in Patients With KIR AA Genotype

Immunomodulatory Drugs | Killer-cell Immunoglobulin-like Receptors (KIRs) | KIR Alleles (KIR AA)

Romania
Theodor Bilharz Research Institute

Completed

Synergistic Immunomodulatory Effect of Synbiotics Pre and Postoperative Resection of Pancreatic Ductal Adenocarcinoma (PDAC)

Pancreatic Ductal Adenocarcinoma

Egypt
Janssen-Cilag Ltd.
Legend Biotech

Completed

A Study of Real-life Current Standards of Care in Patients With Relapsed and/or Refractory Multiple Myeloma Who Received at Least 3 Prior Lines of Therapy Including Proteasome Inhibitor (PI), Immunomodulatory Drug (IMID), and Cluster of Differentiation 38 (CD38) Monoclonal Antibody Treatment (LocoMMotion)

Multiple Myeloma

Belgium, United States, United Kingdom, Italy, Germany, Netherlands, Spain, France, Russian Federation, Poland
Radboud University Medical Center

Completed

The Immunomodulatory Effect of Sugammadex After Total Hip Replacement Surgery Under Neuraxial Anaesthesia: a Pilot Study (MAGIC)

Osteoarthritis, Hip | Innate Inflammatory Response

Netherlands
National Cancer Institute (NCI)

Active, not recruiting

Lenalidomide Combined With Modified DA-EPOCH and Rituximab (EPOCH-R2) in Primary Effusion Lymphoma or KSHV-associated Large Cell Lymphoma

Primary Effusion Lymphoma | B-Cell Neoplasm

United States
University Hospital, Caen

Completed

Identification of Immunomodulators Associated With Atrial Fibrillation Reporting: Analysis of the WHO Pharmacovigilance Database

Atrial Fibrillation

France
Celgene

Active, not recruiting

Study of ACY-241 Alone and in Combination With Pomalidomide and Dexamethasone in Multiple Myeloma

Multiple Myeloma

United States, France, Spain, Germany, Greece
AVM Biotechnology Inc

Available

Expanded Access to Immunomodulatory AVM0703 for Solid Tumor and Blood Cancer Patients

Cancer | Breast Cancer | Glioblastoma | Gastric Cancer | Pancreatic Cancer | Hodgkin Lymphoma | Ovarian Cancer | Prostate Cancer | Acute Leukemia | Non-hodgkin Lymphoma | Squamous Cell Carcinoma | Tumor, Solid | Tumor, Brain | Spindle Cell Sarcoma

Search clinical trials for: Immunomodulatory Drugs (IMiDs)

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Uganda

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations