Search clinical trials for: Immunomodulatory treatment

Total 63222 results

University Hospital, Bordeaux

Not yet recruiting

Evaluation of the Efficacy of Immunomodulatory Therapy in Case of Psychiatric Disorders With Proven Dysimmunity. (TIM-DePisT)

Mental Disorder

France
Fudan University

Recruiting

Famitinib in Combination With Camrelizumab and TPC in The First-line Treatment of Immunomodulatory Locally Advanced or Metastatic TNBC.

Triple-Negative Breast Cancer

China
Lucie Heinzerling

Recruiting

Treatment of Immune-related Adverse Events Refractory to Standard Therapy and Associated Changes in Immunophenotype (PRIA)

Immune-related Adverse Event

Germany
Region Örebro County

Recruiting

A Randomized Controlled Trial With Rituximab for Psychotic Disorder in Adults (RCT-RITS)

Schizophrenia Spectrum and Other Psychotic Disorders

Sweden
Alpha Tau Medical LTD.

Recruiting

A Safety and Efficacy Study for Combinational Treatment of DaRT and Check Point Inhibitor for Recurrent Unresectable or mHNSCC

Skin Cancer | Head and Neck Squamous Cell Carcinoma | Metastatic Head-and-neck Squamous-cell Carcinoma

Israel
Radboud University Medical Center
CATO-SMS

Recruiting

Dose Escalation Study of Immunomodulatory Nanoparticles (PRECIOUS-01)

Advanced Solid Tumor

Netherlands
Judit Pich

Recruiting

Dendritic Cells Therapy Combined With Immunomodulatory Treatment in Multiple Sclerosis (TolDecCOMBINEM)

Relapsing-Remitting Multiple Sclerosis

Spain
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Cryoablation for the Treatment of Metastatic Cancer

Metastatic Malignant Neoplasm

United States
Bristol-Myers Squibb

Active, not recruiting

Incidence of Hyperpigmentation in Black Patients With Multiple Myeloma Treated With Immunomodulatory Drugs

Multiple Myeloma

United States
Janssen Research & Development, LLC

Completed

A Study of JNJ-54767414 (HuMax CD38) (Anti-CD38 Monoclonal Antibody) in Combination With Backbone Treatments for the Treatment of Patients With Multiple Myeloma

Multiple Myeloma

United States, France, Spain
Amgen

Completed

Efficacy and Safety of AMG 570 in Subjects With Active Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus (SLE)

United States, Korea, Republic of, Australia, Spain, Hungary, Bulgaria, Italy, Mexico, Germany, Japan, France, Greece, Czechia, Argentina, Portugal, Poland, Russian Federation, Hong Kong, Canada
Mayo Clinic

Active, not recruiting

Immunomodulatory Drugs (Lenalidomide With or Without Pomalidomide) in Combination With a Corticosteroid Drug (Dexamethasone) for the Treatment of Multiple Myeloma

Plasma Cell Myeloma | Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma | Smoldering Plasma Cell Myeloma

United States
Calla IVF Center

Completed

Effect of Immunomodulatory Treatment on IVF (in Vitro Fertilization) Outcomes in Patients With KIR AA Genotype

Immunomodulatory Drugs | Killer-cell Immunoglobulin-like Receptors (KIRs) | KIR Alleles (KIR AA)

Romania
Janssen-Cilag Ltd.
Legend Biotech

Completed

A Study of Real-life Current Standards of Care in Patients With Relapsed and/or Refractory Multiple Myeloma Who Received at Least 3 Prior Lines of Therapy Including Proteasome Inhibitor (PI), Immunomodulatory Drug (IMID), and Cluster of Differentiation 38 (CD38) Monoclonal Antibody Treatment (LocoMMotion)

Multiple Myeloma

Belgium, United States, United Kingdom, Italy, Germany, Netherlands, Spain, France, Russian Federation, Poland
National Cancer Institute (NCI)

Active, not recruiting

Lenalidomide Combined With Modified DA-EPOCH and Rituximab (EPOCH-R2) in Primary Effusion Lymphoma or KSHV-associated Large Cell Lymphoma

Primary Effusion Lymphoma | B-Cell Neoplasm

United States
Sociedad Argentina de Reumatologia

Completed

Argentinian Registry of Patients With Rheumatic Diseases and COVID-19 Infection (SAR-COVID)

Rheumatic Diseases

Argentina
InDex Pharmaceuticals

Completed

The Efficacy and Safety of Cobitolimod (Kappaproct®) in Chronic Active Treatment Refractory Ulcerative Colitis Patients (COLLECT)

Colitis, Ulcerative

Czechia, France, Germany, Hungary, Italy, Poland, United Kingdom
University College, London
Cancer Research UK; Celgene

Active, not recruiting

Trial of Immunomodulatory Therapy in High Risk Solitary Bone Plasmacytoma (IDRIS)

Plasmacytoma

United Kingdom
Fudan University

Active, not recruiting

A Trial of Camrelizumab in Combination With Nab-paclitaxel and Famitinib as a First Line Treatment in Patients With Unresectable Locally Advanced or Metastatic Immunomodulatory Triple Negative Breast Cancer(FUTURE-C-PLUS)

Triple-Negative Breast Cancer

China
ImmunityBio, Inc.

Active, not recruiting

Study of the Safety of Therapeutic Treatment With an Immunomodulatory Agent (N-803) in Adults With COVID-19

COVID-19

United States
Haukeland University Hospital
Oslo University Hospital; The Kavli Foundation

Completed

Cyclophosphamide in Myalgic Encephalopathy/ Chronic Fatigue Syndrome (ME/CFS) (CycloME)

Chronic Fatigue Syndrome (CFS) | Myalgic Encephalomyelitis (ME)

Norway
Barretos Cancer Hospital
Farmoquimica S.A.

Completed

Randomized Clinical Trial Evaluating the Efficacy of Topical Imiquimod in High Grade Cervical Intraepithelial Lesions

Cervix Cancer | High Grade Intraepithelial Neoplasia

Brazil
Bosnalijek D.D

Completed

Clinical Trial to Evaluate the Efficacy and Safety of an Immunomodulatory Therapy for the Treatment of Patients With Moderate to Severe COVID-19 Infection

COVID-19 Infection

Bosnia and Herzegovina
Aljazeera Hospital

Completed

The Role of Immunomodulatory Treatment in Success of ICSI in Patients With Autoimmune Thyroiditis

Infertility | Autoimmune Thyroiditis

Egypt
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Ex-vivo Evaluation of the Reactivity of the Immune Infiltrate of Cancers to Treatments With Monoclonal Antibodies Targeting the Immunomodulatory Pathways (MAB IN SITRO)

Cancer

France
University Hospital, Bordeaux

Completed

Balance Benefit / Risk of Immunomodulatory Treatments at the Child and Adolescent for Autoimmune Cytopenia. (VIGICAIRE)

Immunotherapy | Immune Thrombocytopenic Purpura | Autoimmune Hemolytic Anemia | Evan Syndrome
Mehdi Yousefi

Completed

Immunomodulatory Effects of Rapamycin on Pregnancy Rate of Patient With Recurrent Implantation Failure

Recurrent Implantation Failure

Iran, Islamic Republic of
University of Chicago

Terminated

Statins for the Early Treatment of Sepsis (SETS)

Sepsis

United States
GlaxoSmithKline

Completed

Establishing Predictors of Enlarged Prostate Treatment Adherence: Linking Symptom Improvement to Adherence

Prostatic Hyperplasia
University Health Network, Toronto
Celgene Corporation

Completed

Open-Label Study of Lenalidomide in Combination With Oral Dexamethasone in the Treatment of Previously Untreated, Symptomatic Patients With Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

Canada
Emory University
Baxter Healthcare Corporation

Terminated

IVIG Treatment for Refractory Immune-Related Adult Epilepsy

Seizure Disorder | Epilepsy, Partial | Epilepsy, Cryptogenic | Autoimmune Diseases, Nervous System | Limbic Encephalitis

United States
Genzyme, a Sanofi Company

Completed

An Exploratory Study of the Safety and Efficacy of Prophylactic Immunomodulatory Treatment in Myozyme-naive Cross-Reacting Immunologic Material (CRIM[-]) Patients With Infantile-Onset Pompe Disease

Glycogen Storage Disease Type II | Pompe Disease

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Hoffmann-La Roche; Sanquin Research & Blood Bank Divisions

Unknown

Mycophenolate Mofetil in Antiretroviral Naïve Patients 2 (MAN2 Study)

HIV Infection

Netherlands
Cytos Biotechnology AG

Completed

Study to Investigate an Immunomodulatory Therapy in Adult Patients With Perennial Allergic Rhinoconjunctivitis

Perennial Allergy to House Dust Mite and/or Cat

Estonia, Latvia, Lithuania
Belgian Inflammatory Bowel Disease Research and...
Schering-Plough; Centocor BV

Completed

Top Down Versus Step Up Strategies in Crohn's Disease

Crohn's Disease

Belgium
Universitätsklinikum Hamburg-Eppendorf

Recruiting

Hyaluronic Acid Delivery: CO2 Laser Versus Thulium Laser Treatment

Aging Skin

Germany
JIANG LONGWEI
Nanjing University

Recruiting

A Study of Tumor Neoantigen-specific T Cells in the Treatment of Advanced Solid Tumors (Neoantigen-T)

Tumor, Solid

China
Chia Tai Tianqing Pharmaceutical Group Nanjing...

Not yet recruiting

A Study of TQB2102 for Injection in the Treatment of HER2-positive Biliary Tract Cancer

Biliary Tract Cancer

China
Universitätsklinikum Hamburg-Eppendorf

Recruiting

Tattoo Particles: Picosecond Laser Versus Nanosecond Laser

Tattoo; Pigmentation

Germany
The Royal's Institute of Mental Health Research

Recruiting

Behavioural Activation Therapy and Esketamine for Resistant Depression

Bipolar Disorder | Depressive Disorder, Major | Depressive Disorder, Treatment-Resistant

Canada
Fundación GECP

Not yet recruiting

Study of Treatment With Sacituzumab and Zimberelimab for Patients With Lung Cancer Confined to the Chest and Previously Operated on Who Were Not Disease-free. (ARIAN)

Lung Diseases | Carcinoma, Non-Small-Cell Lung | Resectable Lung Non-Small Cell Carcinoma

Spain
Nanjing First Hospital, Nanjing Medical University

Recruiting

Effect of Strontium-90 Brachytherapy Combined With Hyperthermia in the Treatment of Keloid

Keloid

China
China National Center for Cardiovascular Diseases

Recruiting

Potts-shunt for the Treatment of Pediatric Patients With Severe Pulmonary Hypertension

Pulmonary Artery Hypertension

China
Ba Yi
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Clinical Study of Irinotecan Hydrochloride Liposome Combined With Capecitabine for Second-line Treatment in Patients With Advanced or Metastatic Biliary Tract Carcinoma

Biliary Tract Carcinoma

China
Medical University of Vienna
Lund University; Ziekenhuis Netwerk Antwerpen (ZNA); St. Antonius Hospital; Azienda... and other collaborators

Not yet recruiting

Outcomes of Local Treatment for Oligometastatic Prostate Cancer Diagnosed Using PSMA PET Imaging: OLIGOMET Study (OLIGOMET)

Prostate Cancer | Prostate Cancer Metastatic | Oligometastasis | Prostate Neoplasm | Oligometastatic Disease | Prostate Cancer Metastatic to Bone
Cellerys AG
Novartis; Tetec AG; Scope International AG; Jung Diagnostics GmbH

Not yet recruiting

Peptide-coupled Red Blood Cells for the Treatment of Multiple Sclerosis (RED4MS)

Relapsing-remitting Multiple Sclerosis (RRMS)
Beijing Tiantan Hospital

Not yet recruiting

Comparative Effectiveness of Intervention in Multi-level Hospitals for Acute Traumatic Brain Injury(Metric-TBI)

Traumatic Brain Injury

China
Zhangyu Bu

Not yet recruiting

Peginterferon α-2b Combined CO2 Laser in Condylomata Acuminata

Condylomata Acuminata

China
Nanfang Hospital, Southern Medical University

Not yet recruiting

PD-L1 Inhibitor Combined With Apatinib as First-line Maintenance Treatment for Extensive-stage Small Cell Lung Cancer

Small Cell Lung Cancer Extensive Stage
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Neoadjuvant Comprehensive Treatment for Unresectable Esophageal Cancer (NEXUS-2)

Esophagus Cancer

China

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