Search clinical trials for: Inadequate glycaemic control

Total 45919 results

AstraZeneca

Completed

Efficacy and Safety of Dapagliflozin and Dapagliflozin Plus Saxagliptin in Combination With Metformin in Type 2 Diabetes Patients Compared With Sulphonylurea

Type 2 Diabetes Mellitus | Inadequate Glycaemic Control

Germany, Slovakia, Czechia, Hungary, Poland
AstraZeneca

Completed

A Multi-Center, Randomized, Double-Blind, Phase III Trial to Evaluate the Safety and Efficacy of Saxagliptin Co-administered With Dapagliflozin Compared to Saxagliptin or Dapagliflozin All Given as add-on Therapy to Metformin in Subject With Type 2 Diabetes

Type 2 Diabetes Mellitus | Inadequate Glycaemic Control

United States, Canada, Czechia, Germany, Russian Federation, Mexico
AstraZeneca

Completed

Evaluate the Efficacy and Safety of Saxagliptin in Combination With Metformin IR Compared to Saxagliptin Monotherapy and to Metformin IR Monotherapy in Drug Naive Chinese Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control

Type 2 Diabetes Mellitus

China
AstraZeneca

Completed

Evaluate the Efficacy and Safety of Saxagliptin Added to Insulin Monotherapy or to Insulin Combined With Metformin in Chinese Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control

Type 2 Diabetes Mellitus

China
Novo Nordisk A/S

Completed

A Trial Comparing the Glycaemic Control of Levemir® Administered Once Daily According to Two Insulin Detemir Titration Algorithms After 20 Weeks in Subjects With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin Treatment With or Without Other Anti-diabetic Drugs (OADs)

Diabetes Mellitus, Type 2 | Diabetes

Korea, Republic of
Novo Nordisk A/S

Completed

Effect of Different Insulin Administrations, All in Combination With Metformin, on Glycaemic Control in Subjects With Type 2 Diabetes Inadequately Controlled by Oral Anti-diabetic Drugs

Diabetes Mellitus, Type 2 | Diabetes

Morocco, Tunisia, Algeria, South Africa, Egypt
Vastra Gotaland Region
Novo Nordisk A/S

Completed

Addition of Liraglutide to Patients With Type 2 Diabetes Treated With Multiple Daily Insulin Injections

Type 2 Diabetes Mellitus

Sweden
Boehringer Ingelheim
Eli Lilly and Company

Completed

Linagliptin Versus Placebo in Type 2 Diabetic Patients With Inadequate Glycaemic Control on Metformin in Combination With Pioglitazone

Diabetes Mellitus, Type 2

United States, France, India, Philippines
AstraZeneca
Bristol-Myers Squibb

Completed

Evaluation of Safety and Efficacy of Dapagliflozin in Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control on Background Combination of Metformin and Sulfonylurea

Type 2 Diabetes Mellitus | Inadequate Glycaemic Control | High HbA1c Level

Czech Republic, Poland, Spain, Germany, Canada, Slovakia
AstraZeneca
Bristol-Myers Squibb

Completed

Efficacy and Safety in Patients With Type 2 Diabetes Mellitus and Cardiovascular Disease

Cardiovascular Disease | Type 2 Diabetes Mellitus | Inadequate Glycaemic Control

United States, Bulgaria, Poland, Hungary, Argentina, Australia, Austria, Canada, Germany, Chile
AstraZeneca
Bristol-Myers Squibb

Completed

Efficacy and Safety in Patients With Type 2 Diabetes Mellitus, Cardiovascular Disease and Hypertension

Hypertension | Cardiovascular Disease | Type 2 Diabetes Mellitus | Inadequate Glycaemic Control

United States, Vietnam, Germany, Romania, Canada, Argentina, Slovakia, Taiwan, Spain
AstraZeneca
Bristol-Myers Squibb

Completed

Saxagliptin Triple Oral Therapy

Type 2 Diabetes

Korea, Republic of, United Kingdom, Australia, Canada, Thailand, India
AstraZeneca
Bristol-Myers Squibb

Suspended

Evaluation of Efficacy and Safety of Dapagliflozin as Monotherapy in Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control With Diet and Exercise Alone

Type 2 Diabetes

India
Steno Diabetes Center Copenhagen

Completed

Effect of Metformin in Patients With Type-1 Diabetes With Inadequate Glycaemic Control by Insulin and Diet

Diabetes Mellitus, Type 1
HighTide Biopharma Pty Ltd
Shenzhen HighTide Biopharmaceutical Ltd.

Recruiting

Effects of Berberine Ursodeoxycholate (HTD1801) Versus Dapagliflozin in Patients With Type 2 Diabetes Inadequately Controlled With Metformin

T2DM (Type 2 Diabetes Mellitus)

China
Eli Lilly and Company

Not yet recruiting

Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (TRANSCEND-T2D-1)

Diabetes Type 2

United States, India, Mexico, Puerto Rico
HighTide Biopharma Pty Ltd

Recruiting

Efficacy and Safety of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes Inadequately Controlled With Metformin

Type 2 Diabetes Mellitus

China
Aalborg University Hospital

Recruiting

The Effect of Adherence to Oral Semaglutide on Glycaemic Control in People With Type 2 Diabetes Treated With Metformin (DIACRON)

Diabetes Mellitus, Type 2

Denmark
IRCCS Burlo Garofolo

Recruiting

Determinants of Glycaemic Control in Children With Type 1 Diabetes

Diabetes Mellitus, Type 1

Italy
Eli Lilly and Company

Recruiting

Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)

Type 2 Diabetes

United States, Argentina, United Kingdom, Puerto Rico
Dong-A ST Co., Ltd.

Not yet recruiting

Efficacy and Safety of DA5221-T When Added to Ongoing DA5221-B1 and DA5221-B2 Combination Therapy in Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control

Type 2 Diabetes

Korea, Republic of
Eli Lilly and Company

Recruiting

Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)

Diabetes Mellitus, Type 2

United States, Canada, Mexico, Argentina, Puerto Rico
Eli Lilly and Company

Recruiting

A Study of Orforglipron (LY3502970) Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin (ACHIEVE-2)

Type 2 Diabetes

United States, Taiwan, China, Mexico, Germany, Poland
Steno Diabetes Center Copenhagen

Recruiting

The ACCT2 Study Individuals With Type 2 Diabetes and Non-Western Backgrounds (ACCT2) (ACCT2)

Type 2 Diabetes

Denmark
Nora Hussein Kamal

Not yet recruiting

Evaluate the Role of Soleus Muscle Exercise in Glycaemic Control in Diabetic Kidney Disease Patients

Diabetic Kidney Disease
Eli Lilly and Company

Recruiting

A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes and Inadequate Glycemic Control With Insulin Glargine, With or Without Metformin and/or SGLT-2 Inhibitor (ACHIEVE-5)

Type 2 Diabetes

United States, Japan, China, Puerto Rico, Romania, Brazil
Eli Lilly and Company

Recruiting

A Study of Orforglipron (LY3502970) Compared With Semaglutide in Participants With Type 2 Diabetes Inadequately Controlled With Metformin (ACHIEVE-3)

Type 2 Diabetes

United States, China, Japan, Argentina, Puerto Rico, Mexico
Novartis Pharmaceuticals

Recruiting

A Study to Investigate Efficacy, Safety, and Tolerability of Remibrutinib Compared With Placebo in Adults With CINDU Inadequately Controlled by H1-antihistamines

Chronic Inducible Urticaria

China, United States, Australia, Korea, Republic of, Israel, Turkey, Hong Kong, Japan, Malaysia, Singapore, Argentina, Thailand, Canada
Eli Lilly and Company

Recruiting

A Study of Orforglipron (LY3502970) in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (ACHIEVE-1)

Type 2 Diabetes

United States, Mexico, Japan, India, Puerto Rico, China
Ningbo No. 1 Hospital

Recruiting

Effectiveness of Mannitol Versus Polyethylene Glycol Electrolyte Dispersion as a Salve for Patients With Inadequate Bowel Preparation: a Randomized Controlled Clinical Trial

Bowel Cleansing; Good Taste

China
University of Aberdeen

Recruiting

Scot Sweet Study (Interaction of a Non-nutritive Sweetener With a High-fibre Weight Loss Diet) (SSS)

Appetitive Behavior

United Kingdom
Incyte Corporation

Recruiting

A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Inadequately Controlled Moderate to Severe Asthma

Moderate to Severe Asthma

Korea, Republic of, United States, Spain, Poland, Japan, Canada, Germany, Belgium, Argentina
AstraZeneca

Recruiting

A 12-week Study to Assess the Efficacy and Safety of Budesonide and Formoterol Fumarate Metered Dose Inhaler Relative to Budesonide Metered Dose Inhaler in Participants With Inadequately Controlled Asthma (LITHOS) (LITHOS)

Asthma

United States, Canada, South Africa, Korea, Republic of, Philippines, Czechia, Malaysia, Germany
Dong-A ST Co., Ltd.

Recruiting

Clinical Trial to Evaluate the Efficacy and Safety of DA-2811 When Added to Ongoing Metformin Monotherapy in Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control

Diabetes Mellitus

Korea, Republic of
University of Adelaide

Recruiting

Effects of Intragastric Quinine, Alone or Combined With L-leucine, on Postprandial Glycaemic Control

Healthy

Australia
NYU Langone Health
Arthritis Foundation

Recruiting

Effects of Administration of SCFA in Rheumatoid Arthritis Inadequate Responders (EASi-RAIR)

Rheumatoid Arthritis

United States
University of Adelaide

Recruiting

Effects of Intragastric Quinine, Alone or Combined With L-isoleucine, on Postprandial Glycaemic Control

Healthy

Australia
Novartis Pharmaceuticals

Recruiting

24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up

Chronic Spontaneous Urticaria

United States, Singapore, Spain, Germany, Turkey, Italy, Hong Kong, China, Argentina, Malaysia, Thailand, Poland, Japan, Netherlands, Chile, Canada
Hyundai Pharm

Recruiting

Efficacy and Safety of HD-6277 in Adult Patients With Inadequate Control of Type 2 Diabetes Mellitus by Diet and Exercise

Type 2 Diabetes Mellitus

Korea, Republic of
SynAct Pharma Aps
NBCD A/S

Recruiting

A Dose-range Study of the Safety and Efficacy of Treatment in Adult Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate (RESOLVE)

Rheumatoid Arthritis

Moldova, Republic of
Sarawak General Hospital
CRAUN Research Sdn. Bhd.

Recruiting

Effect of Sago-based Product on Glycaemic and Lipid Control in Diabetes (SAGODM)

Diabetes Mellitus, Type 2

Malaysia
Lancaster University
East Lancashire Hospitals NHS Trust

Recruiting

A Case-control Study Comparing Glycaemic Control in Pancreatic Cancer Patients vs Healthy Matched Individuals. (PanCanCGM)

Pancreatic Cancer

United Kingdom
Forschungsinstitut der Diabetes Akademie Mergentheim

Recruiting

Precision Mental Health in Diabetes - Subtypes of Mental Health, Trajectories, and Patterns With Glycaemic Control (PRO-MENTAL)

Depressive Disorder | Hyperglycemia | Diabetes Mellitus | Anxiety Disorders | Depressive Symptoms | Emotional Distress | Eating Disorders | Eating Behavior | Anxiety and Fear | Eating Disorder Symptom

Germany
Handok Inc.

Recruiting

Clinical Efficacy and Safety Evaluation of Teneligliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Empaglyflozin and Metformin (TERA 304)

Type 2 Diabetes

Korea, Republic of
Ahn-Gook Pharmaceuticals Co.,Ltd
Daehwa Pharmaceutical Co., Ltd.

Not yet recruiting

Phase III Study to Evaluate the Efficacy and Safety of AGSAVI in Patients With Essential Hypertension Inadequately Controlled With AGLS

Essential Hypertension
Handok Inc.

Recruiting

Clinical Efficacy and Safety Evaluation of Teneligliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Empaglyflozin 25 mg and Metformin (TERA 305)

Type 2 Diabetes

Korea, Republic of
University of Nottingham
Nottingham University Hospitals NHS Trust

Not yet recruiting

Effect of Consuming Products Containing Rare Sugars Alongside Sucrose on Glycaemic Response in Healthy Adults

Glycaemic Response in Healthy Participants

United Kingdom
Jeil Pharmaceutical Co., Ltd.

Recruiting

To Evaluate the Efficacy and Safety of JT-003 add-on in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin

Type 2 Diabetes Mellitus

Korea, Republic of
AstraZeneca

Recruiting

A 24-Week Efficacy and Safety Study to Assess Budesonide and Formoterol Fumarate Metered Dose Inhaler in Adult and Adolescent Participants With Inadequately Controlled Asthma (VATHOS) (VATHOS)

Asthma

United States, Canada, Italy, Japan, Vietnam, Spain, Germany, Malaysia
Karuna Therapeutics

Recruiting

A Study to Assess Efficacy and Safety of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia (ARISE)

Schizophrenia

United States, Bulgaria, Serbia

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