Search clinical trials for: Intra hepatic Cholangiocarcinoma

Total 34028 results

Hutchmed

Completed

HMPL-453 Food Effect and PPI Study in Healthy Volunteer Study

Intrahepatic Cholangiocarcinoma

China
University of Pennsylvania
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Active, not recruiting

Adrenergic System in Islet Transplantation

Hypoglycemia | Type1diabetes | Islet Cell Transplantation | Hypoglycemia Unawareness

United States
University of Florida

Completed

Liver Fibrosis in Alpha-1 Antitrypsin Deficiency (Liver AATD)

Alpha-1 Antitrypsin Deficiency | Liver Fibrosis | AATD | AAT Deficiency

United States
Mayo Clinic
National Comprehensive Cancer Network

Completed

Trifluridine/Tipiracil and Irinotecan for the Treatment of Advanced Refractory Biliary Tract Cancer

Stage III Gallbladder Cancer AJCC v8 | Stage IIIA Gallbladder Cancer AJCC v8 | Stage IIIB Gallbladder Cancer AJCC v8 | Refractory Gallbladder Carcinoma | Stage IV Gallbladder Cancer AJCC v8 | Stage IV Distal Bile Duct Cancer AJCC v8 | Stage IV Intrahepatic Bile Duct Cancer AJCC v8 | Stage IVB Gallbladder... and other conditions

United States
NCIC Clinical Trials Group

Terminated

Gemcitabine With/Out Capecitabine in Locally Advanced, Unresectable, or Metastatic Biliary Cancer

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

Canada
Centre hospitalier de l'Université de Montréal...
University of Alberta; McGill University Health Centre/Research Institute of... and other collaborators

Completed

Intraoperative Hemodynamic Management and Postoperative Outcomes in Liver Transplantation (ELIPTO-2)

Liver Diseases | Liver Failure | Surgery | Surgery--Complications | Transplant; Failure, Liver

Canada
University Health Network, Toronto

Enrolling by invitation

Liver Transplant for Stable, Advanced Intrahepatic Cholangiocarcinoma

Cholangiocarcinoma, Intrahepatic

Canada
Peking University

Completed

HAIC With Oxaliplatin, 5-FU and Bevacizumab Plus Intravenous Toripalimab for Advanced BTC

Advanced Biliary Tract Cancer

China
Celldex Therapeutics

Completed

A Study of the PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced Malignancies

Renal Cell Carcinoma | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Cholangiocarcinoma | Non-small Cell Lung Cancer | Primary Peritoneal Carcinoma | Hepatic Cancer | Bladder Urothelial Carcinoma | Other Solid Tumors | MSI-H Colorectal Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Ramucirumab in Treating Patients With Advanced or Metastatic, Previously Treated Biliary Cancers That Cannot Be Removed by Surgery

Cholangiocarcinoma | Liver and Intrahepatic Bile Duct Carcinoma | Unresectable Gallbladder Carcinoma | Stage III Gallbladder Cancer AJCC v7 | Stage IIIA Gallbladder Cancer AJCC v7 | Stage IIIB Gallbladder Cancer AJCC v7 | Stage IV Gallbladder Cancer AJCC v7 | Stage IVA Gallbladder Cancer AJCC v7 | Stage... and other conditions

United States
Basilea Pharmaceutica
ArQule, Inc. (a wholly owned subsidiary of Merck Sharp and Dohme, a subsidiary...

Completed

Phase 1/2 Study of Derazantinib (ARQ 087) in Adult Subjects With Advanced Solid Tumors With FGFR Genetic Alterations

Solid Tumor

United States, Italy
NuCana plc

Terminated

Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer

Biliary Tract Cancer

Canada, United States, Spain, Hungary, Korea, Republic of, United Kingdom, Czechia, Germany, Russian Federation, Australia, France, Taiwan, Ukraine, Italy, Turkey
Basilea Pharmaceutica

Available

Expanded Access Use of Derazantinib for Advanced Intrahepatic Cholangiocarcinoma (iCCA) With FGFR Genomic Alterations

Intrahepatic Cholangiocarcinoma
Emory University
National Cancer Institute (NCI); National Institutes of Health (NIH); Celgene

Active, not recruiting

Gemcitabine, Cisplatin, and Nab-Paclitaxel Before Surgery in Patients With High-Risk Liver Bile Duct Cancer

Resectable Cholangiocarcinoma | Stage IB Intrahepatic Cholangiocarcinoma AJCC v8 | Stage II Intrahepatic Cholangiocarcinoma AJCC v8 | Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8 | Stage IIIB Intrahepatic Cholangiocarcinoma AJCC v8

United States
Dartmouth-Hitchcock Medical Center
National Cancer Institute (NCI)

Completed

An Intraoperative Guidance Platform for Radio Frequency Ablation

Hepatocellular Carcinoma

United States
Sirtex Medical

Completed

SIRT Followed by CIS-GEM Chemotherapy Versus CIS-GEM Chemotherapy Alone as 1st Line Treatment of Patients With Unresectable Intrahepatic Cholangiocarcinoma (SIRCCA)

Intrahepatic Cholangiocarcinoma

France, United Kingdom, Belgium, Australia, Spain, United States, Italy, Netherlands
RedHill Biopharma Limited

Completed

A Study of ABC294640 (Yeliva ®) Alone and in Combination With Hydroxychloroquine Sulfate in Treatment of Patients With Advanced Cholangiocarcinoma

Cholangiocarcinoma | Cholangiocarcinoma Non-resectable | Cholangiocarcinoma, Perihilar | Cholangiocarcinoma, Extrahepatic | Cholangiocarcinoma, Intrahepatic

United States
Xencor, Inc.
ICON Clinical Research

Completed

A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors (DUET-4)

Melanoma | Renal Cell Carcinoma | Nasopharyngeal Carcinoma | Small Cell Lung Carcinoma | Hepatocellular Carcinoma | Fallopian Tube Cancer | Non-small Cell Lung Carcinoma | Squamous Cell Carcinoma of the Head and Neck | Triple Negative Breast Cancer | Epithelial Ovarian Cancer | Intrahepatic Cholangiocarcinoma and other conditions

United States
Peking Union Medical College Hospital

Completed

Lenvatinib Combined Pembrolizumab in Advanced Hepatobiliary Tumors

Cholangiocarcinoma | Biomarker | Combinational Immunotherapy | Liver Neoplasm Malignant Primary

China
National Cancer Institute (NCI)

Completed

A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)

Hepatocellular Carcinoma | Cholangiocarcinoma | Bile Duct Cancer | Biliary Tract Neoplasms | Liver Cancer

United States
Ottawa Hospital Research Institute

Active, not recruiting

Hypovolemic Phlebotomy to Reduce Blood Transfusions in Major Hepatic Resections (PRICE2)

Liver Neoplasms | Hepatectomy | Blood Loss, Surgical | Blood Transfusion

Canada
Intensity Therapeutics, Inc.
Bristol-Myers Squibb; Merck Sharp & Dohme LLC

Completed

A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6 (IT-01)

Sarcoma | Lymphoma | Breast Cancer | Head and Neck Cancer | Pancreatic Cancer | Lung Cancer | Bile Duct Cancer | Colon Cancer | Liver Cancer | Squamous Cell Carcinoma | Chordoma of Sacrum

United States, Canada
First Affiliated Hospital of Zhejiang University
LanZhou University

Enrolling by invitation

The Precise Selection of Stent Diameter for Portal Hypertension Patients With TIPS

Portal Hypertension | Compensated Advanced Chronic Liver Disease

China
Children's Hospital of Fudan University

Withdrawn

BSEP Function Rescue During Childhood Inhereditary Cholestatic Diseases

Cholestasis, Intrahepatic | Hereditary Diseases
Bayer

Completed

Study on the Safety of BAY1817080, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug in Participants With Impaired Liver Function or Normal Liver Function

Overactive Bladder | Diabetic Neuropathic Pain | Endometriosis Related Pain | Refractory or Unexplained Chronic Cough

United States
Quadriga Biosciences, Inc.
Novotech (Australia) Pty Limited

Completed

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S

Melanoma | Sarcoma | Kidney Cancer | Cervical Cancer | Breast Cancer | Head and Neck Cancer | Astrocytoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Thymic Carcinoma | Lung Cancer | Prostate Cancer | Brain Cancer | Cholangiocarcinoma | Bladder Cancer | Liver Cancer | Brain Metastases | Tongue Cancer | Esophagus... and other conditions

Australia
Leiden University Medical Center
Mirada Medical

Completed

Intraprocedural Assessment of Ablation Margins Using Computed Tomography Co-registration in Primary Liver Tumor Treatment With Percutaneous Ablation (IAMCOMPLETE)

HCC

Netherlands
University Hospital, Montpellier

Withdrawn

The Impact on Hepatic Recurrence After Adjuvant Chemotherapy With Intraarterial Infusion of Idarubicin-Lipiodol (LIDA-ADJ)

Hepatocellular Carcinoma

France
Centre hospitalier de l'Université de Montréal...

Completed

Fibrinogen and Intraoperative Bleeding in Liver Transplant (FIB_TOF)

Liver Transplant; Complications | End Stage Liver DIsease

Canada
Centre hospitalier de l'Université de Montréal...
Sunnybrook Health Sciences Centre; University of Alberta; Unity Health Toronto; University of Kentucky and other collaborators

Completed

Ultrasound Markers of Organ Congestion in Severe Acute Kidney Injury (ECHO-AKI)

Acute Kidney Injury | Ultrasonography | Fluid Overload

Canada, United States
Marnix Lam

Completed

Intra-arterial Lutetium-177-dotatate for Treatment of Patients With Neuro-endocrine Tumor Liver Metastases (LUTIA)

Neuroendocrine Tumors | Liver Metastases

Netherlands
Brigham and Women's Hospital
Columbia University

Completed

Treatments Against RA and Effect on FDG-PET/CT (TARGET)

Arthritis, Rheumatoid

United States
Air Force Military Medical University, China

Completed

Embolization of Large Spontaneous Portosystemic Shunts for the Prevention of Post-TIPS Hepatic Encephalopathy

Liver Cirrhosis

China
Sulai Liu

Active, not recruiting

Research on Effectiveness and Safety of the Treatment, Hyperthermic Intraperitoneal Chemotherapy Combined With Tislelizumab and Targeted Therapy, That is Used for High-risk Hepatocellular Carcinoma After R0 Resection

Hepatocellular Carcinoma

China
Memorial Sloan Kettering Cancer Center

Completed

Trial of IRE in Cholangiocarcinoma

Cholangiocarcinoma

United States
Intercept Pharmaceuticals

Terminated

Study of Obeticholic Acid (OCA) Evaluating Pharmacokinetics and Safety in Participants With Primary Biliary Cholangitis (PBC) and Hepatic Impairment

Liver Cirrhosis, Biliary

United States, Argentina, Spain, Belgium, Germany, Canada, Australia, Estonia, Brazil, Hungary, Italy, Lithuania
University of Texas Southwestern Medical Center

Completed

A Pilot Study of "OncozeneTM" Microspheres for Intra-arterial Delivery of Doxorubicin

Hepatocellular Cancer

United States
Postgraduate Institute of Medical Education and...

Completed

Intravenous Branched Chain Amino Acids for Hepatic Encephalopathy in ACLF (BCAA-ACLF)

Acute-On-Chronic Liver Failure | Hepatic Encephalopathy

India
Washington University School of Medicine

Terminated

Hepatic Arterial Infusion in Treating Patients With Locally Advanced, Non-Metastatic Cholangiocarcinoma

Liver Neoplasms | Cholangiocarcinoma

United States
Humanitas Clinical and Research Center

Completed

Study on the Quality of Life (QoL) After Liver Surgery

Quality of Life | Cholangiocarcinoma | Hepatocarcinoma

Italy
Intercept Pharmaceuticals
Syneos Health; Global PBC Study Group; Target RWE; UK PBC Group

Completed

Real-World Data Study to Evaluate the Effectiveness of OCA on Hepatic Outcomes in PBC Patients (HEROES PBC)

Primary Biliary Cholangitis

United States
Gang Chen, MD

Enrolling by invitation

Observational Study on Patients With Hepatobiliary Tumors

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Cholangiocarcinoma | Biliary Tract Cancer | Gallbladder Cancer

China
Samsung Medical Center

Withdrawn

A Single-arm Study of Gemcitabine, Cisplatin, and Nab-Paclitaxel as Neoadjuvant Therapy for Resectable Oncologically High-Risk IHCC in Korea

Intrahepatic Cholangiocarcinoma
Mylan Specialty, LP

Terminated

Intravenous Milk Thistle (Silibinin-Legalon) for Hepatic Failure Induced by Amatoxin/Amanita Mushroom Poisoning

Liver Failure | Amatoxin Poisoning | Amanita Poisoning | Mushroom Poisoning

United States
Fudan University

Withdrawn

GP Chemotherapy in Combination With Tislelizumab and Ociperlimab as First-line Treatment in Advanced BTC

Intrahepatic Cholangiocarcinoma

China
Rajavithi Hospital

Completed

Efficacy of Intraductal Radiofrequency Ablation in Combination With Metallic Biliary Stenting in Advanced Hilar Cholangiocarcinoma

Hilar Cholangiocarcinoma | Biliary Obstruction

Thailand
Coordinación de Investigación en Salud, Mexico

Terminated

Effycacy of Rifaximin on Reverse Minimal Hepatic Encephalopathy and Elimation Small Intestinal Bacterial

Liver Cirrhosis | Small Intestinal Bacterial Overgrowth

Mexico
RedHill Biopharma Limited

Available

Expanded Access for the Treatment of Advanced Cholangiocarcinoma With ABC294640 (Yeliva ®)

Cholangiocarcinoma | Cholangiocarcinoma Non-resectable | Cholangiocarcinoma, Perihilar | Cholangiocarcinoma, Extrahepatic | Cholangiocarcinoma, Intrahepatic
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Gemcitabine Hydrochloride, Cisplatin, and Nab-Paclitaxel in Treating Patients With Advanced or Metastatic Biliary Cancers

Unresectable Extrahepatic Bile Duct Carcinoma | Unresectable Gallbladder Carcinoma | Stage IIIA Gallbladder Cancer AJCC v7 | Stage IIIB Gallbladder Cancer AJCC v7 | Stage IVA Gallbladder Cancer AJCC v7 | Stage IVB Gallbladder Cancer AJCC v7 | Stage III Intrahepatic Cholangiocarcinoma AJCC v7 | Stage... and other conditions

United States
Duke University

Terminated

BRIDGE Device for Post-operative Pain Control (BRIDGE)

Liver Diseases | Liver Failure | Pain, Postoperative | Liver Diseases, Alcoholic | Liver Cirrhosis, Biliary | Transplant; Failure, Liver

United States

Search clinical trials for: Intra hepatic Cholangiocarcinoma

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