Search clinical trials for: Intranasal challenge

Total 2283 results

Medical University of Vienna

Recruiting

Contribution of Nasal IgE Production to the Boost of Systemic Allergen-specific IgE Upon Nasal Allergen Contact

Allergy

Austria
Imperial College London
Royal College of Surgeons, Ireland; University of Manchester

Enrolling by invitation

Improved Diagnostics in Food Allergy Study (ID-in-FA)

Food Allergy

United Kingdom, Ireland
Imperial College London
National Institute for Health Research, United Kingdom

Completed

Intranasal Diagnostics in Food Allergy: a Feasibility Study (INDY)

Food Allergy

United Kingdom
Meissa Vaccines, Inc.
Hvivo

Completed

Human Challenge Study to Evaluate the Efficacy of MV-012-968 Vaccine

RSV Infection

United Kingdom
National Institute of Allergy and Infectious Diseases...

Completed

Mucosal and Systemic Immunity After Viral Challenge of Healthy Volunteers Vaccinated With Inactivated Influenza Vaccine Via the Intranasal Versus Intramuscular Route

Influenza

United States
GlaxoSmithKline

Completed

Effects Of Single Doses Of GW784568X On Allergic Rhinitis Symptoms In Male Subjects Whilst In An Environmental Chamber

Rhinitis, Allergic, Perennial

Germany
New York State Psychiatric Institute
Indivior Inc.

Completed

Reinforcing Effects of Intranasal (IN) Buprenorphine Versus Buprenorphine/Naloxone

Heroin Dependence

United States
MedImmune LLC

Terminated

Intranasal Challenge of Healthy Adults With Respiratory Syncytial Virus (RSV)

RSV Infection

United Kingdom
GlaxoSmithKline

Completed

A Study to Assess Intranasal Repeat Dose Effect of Levocabastine in the Subjects With Allergic Rhinitis

Rhinitis, Allergic, Perennial and Seasonal

Canada
GlaxoSmithKline

Completed

Intranasal SB-705498 in Non-allergic Rhinitis Patients

Rhinitis

Netherlands
GlaxoSmithKline

Completed

A Phase II Study Evaluating Intranasal GSK256066 and Fluticasone Propionate in Subjects With Seasonal Allergic Rhinitis (SAR)

Rhinitis, Allergic, Seasonal

Austria
GlaxoSmithKline

Completed

A Study To Investigate If MRI Scanning Is Effective At Seeing What Hayfever Drugs Do In Nasal Passage.

Sinusitis | Seasonal Allergic Rhinitis

United Kingdom
Creighton University
Roche Pharma AG

Completed

Effects of Intranasal Corticosteroid and Montelukast On Nasal Allergen Challenges* (Roche)

Allergy

United States
GlaxoSmithKline

Completed

A Phase II Study Evaluating Intranasal GSK256066 and Azelastine Hydrochloride in Subjects With Seasonal Allergic Rhinitis

Allergic Rhinitis | Rhinitis, Allergic, Seasonal

Austria
GlaxoSmithKline

Completed

Allergen Challenge Chamber Study With Single Dose Intranasal GSK1004723 Compared With Placebo

Allergic Rhinitis

Germany
Pfizer

Completed

Effect of a Nasal Bolus Allergen Challenge on Inflammatory Markers

Seasonal Allergic Rhinitis

United Kingdom
HealthPartners Institute
United States Department of Defense; Uniformed Services University of the Health...

Not yet recruiting

Measurement of Insulin Levels in the Cerebrospinal Fluid of Healthy Adults After a Single Intranasal Dose - Middle Age (INI-CSF-MA)

Healthy

United States
Weill Medical College of Cornell University

Not yet recruiting

Understanding the Efficacy of Dietary Supplement on Fungal Mycobiota in Healthy Volunteers: A Pilot Study

Gut Microbiome | Dietary Supplement | Gut Health | L-Phenylalanine | Phenylpropionic Acid

United States
Cairo University
National Heart Institute, Egypt

Not yet recruiting

Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume Overload

Edema | Acute Decompensated Heart Failure | Volume Overload

Egypt
Fujian Provincial Hospital
Fujian Maternity and Child Health Hospital; Fujian Children's Hospital

Not yet recruiting

Intranasal Dexmedetomidine Versus Oral Midazolam Premedication for Postoperative Negative Behavior Changes in Children

Behavior Problem
McMaster University

Not yet recruiting

Measurements of Inflammation Induced by Allergen Inhalation Challenge in Mild Allergic Asthma (MATT)

Mild Asthma

Canada
University of Texas, El Paso
National Institute on Minority Health and Health Disparities (NIMHD)

Recruiting

Evidence-based Intervention to Improve Walking Engagement in El Paso, Texas

Physical Activity | Activity Trackers

United States
Centre for Human Drug Research, Netherlands

Recruiting

Deep Phenotyping of Cutaneous Lupus Erythematosus

Cutaneous Lupus Erythematosus

Netherlands
University of Leicester
University Hospitals, Leicester

Not yet recruiting

Ischaemic Lesions in Acute Intracerebral Haemorrhage (CHALLENGE-ICH)

Intracerebral Haemorrhage
University of Cologne

Recruiting

Regulation of Extracellular Sodium in End Stage Renal Disease Upon Volume and Electrolyte Challenges (RESERVE)

Hyponatremia

Germany
Massachusetts General Hospital
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing (DACAT)

Drug Hypersensitivity | Drug-Induced Anaphylaxis | Antibiotic Allergy | Drug Allergy | Beta Lactam Adverse Reaction | Cephalosporin Allergy | Cephalosporin Reaction

United States
Lakehead University
Illinois Institute of Technology, Chicago, USA

Recruiting

Honest, Open, Proud - College for Post-Secondary Students With Mental Health Challenges

Mental Health Issue | Stigmatization | Disclosure

Canada
Chinese PLA General Hospital

Not yet recruiting

Chidamide+Decitabine Plus Anti-PD-1 Antibody in PD-1 Inhibitor Failed Patients With Classical Hodgkin Lymphoma.

PD-1 Inhibitor Failed Patients With Classical Hodgkin Lymphoma
Humanitas Clinical and Research Center
European Society of Intensive Care Medicine

Not yet recruiting

Fluid Challenge in Intensive Care The FENICE II Study (FENICE II)

Critical Illness | Septic Shock

Italy
CentraCare

Recruiting

Passive Leg Raise and Mini-fluid Challenge Effect on Various Cardiac Output Surrogates for Fluid Responsiveness (PHOENIX)

Fluid Responsiveness

United States
Erasme University Hospital

Not yet recruiting

Investigating Brain Insulin Resistance In Alzheimer Disease With IntraNasal Insulin : A Multimodal Neuroimaging Study (Memori³)

Alzheimer Disease | Mild Cognitive Impairment
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Peripheral Tissue Perfusion in Intensive Care (INPPEREA)

Acute Circulatory Failure
University Hospital, Caen

Recruiting

Haemodynamic and Respiratory Effects of a Low Positive End Expiratory Pressure Associated With a Fluid Challenge in Knee-chest Position (OPTIPEP)

Surgery

France
State University of New York - Upstate Medical...

Not yet recruiting

Intranasal Dexmedetomidine vs. Standard of Care for Emergency Department (ED) Procedural Sedation in the Older Adult

Altered Mental Status
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

Pharmacology of Mupirocin in Nasal Application in Healthy Volunteers: Monocentric Study (MUPIPHARM)

Healthy | Staphylococcus Aureus Infection

France
Cessatech A/S

Recruiting

Safety, Tolerability, Analgesic Effect, and Feasibility of Intranasal CT001 in Pediatric Patients

Pain

Spain, United Kingdom
University of Nebraska

Not yet recruiting

Intranasal Oxytocin Intervention for Caregivers to Persons With Dementia

Stress

United States
VistaGen Therapeutics, Inc.

Recruiting

Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder (PALISADE-3) (PALISADE-3)

Social Anxiety Disorder

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Timecost of Intranasal Versus Intravenous Analgesia in Traumatic Pain

Analgesia | Acute Pain Due to Trauma

Netherlands
University of Parma
Foundation for Liver Research; Azienda Ospedaliero-Universitaria di Parma; National... and other collaborators

Recruiting

Precision Nutrition to Improve Cardiometabolic Health With Dietary (Poly)Phenols (PRE-CARE-DIET)

Obesity | Cardiometabolic Health | Individual Variability in (Poly)Phenol Metabolism | Personalized Dietary Intervention

Italy
Eli Lilly and Company

Recruiting

A Study of Lebrikizumab (LY3650150) in Adult Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)

Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

Belgium, Italy, United States, Bulgaria
Craig Erickson
Healx Limited

Recruiting

Placebo-Controlled, Single-Dose Challenge Study of Gaboxadol in Adult Males With Fragile X Syndrome (FXS)

Fragile X Syndrome

United States
Insel Gruppe AG, University Hospital Bern
University Hospital, Basel, Switzerland; University Hospital, Zürich; Stadtspital...

Not yet recruiting

Administration of Intranasal Midazolam for Anxiety in Palliative Care (AIM Care)

Anxiety | Acute Anxiety

Switzerland
Fraunhofer-Institute of Toxicology and Experimental...

Recruiting

Development of a Novel Non-invasive Inflammometry Following Allergen Challenge in Patients With Mild Allergic Asthma

Mild Allergic Asthma

Germany
James Tarbox, MD
Texas Tech University Health Sciences Center

Recruiting

Penicillin Allergy Delabeling After a One-Dose Versus Two-Dose Graded Direct Oral Challenge

Penicillin Allergy

United States
Parc de Salut Mar
Food and Drug Administration (FDA)

Recruiting

Pharmacokinetics of Intravenous and Intranasal Formulations of Naloxone in Healthy Volunteers.

Healthy

Spain
University of Michigan

Recruiting

Michigan Food and Atopic Dermatitis (M-FAD) Program - Molecular Analytics Project

Healthy | Atopic Dermatitis | Food Allergy

United States
University of Ulm

Recruiting

Relative Contribution of Brain Insulin Action for Postprandial Metabolism (BrainInsPPM)

Glucose Metabolism Disorders

Germany
Scandinavian Biopharma AB
Johns Hopkins Bloomberg School of Public Health

Recruiting

Pre-Study of Wild Type Enterotoxigenic E. Coli (ETEC) Strain for Verification of a Planned Challenge Dose

ETEC Diarrhea

United States
Kilis 7 Aralik University
Hasan Kalyoncu University

Not yet recruiting

Impact of Workload and Fatigue on Sleep in OR Nurses

Shift Work | Sleep Perception

Turkey

Search clinical trials for: Intranasal challenge

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