Search clinical trials for: Kallikrein-related peptidase-4 (KLK4)

Total 13179 results

Amina Fouad Farag

Completed

Polymorphisms in ENAM, AMBN, and KLK4 Contribute to DCS.

Dental Caries Secondary to Polymorphisms | Polymorphisms in Enamel Encoding Genes

Egypt
Chinese PLA General Hospital

Completed

Plasma Dipeptidyl-peptidase-4 Activities With No-reflow and Bleeding

Bleeding | STEMI | PCI | Dipeptidyl-peptidase-4 | No-reflow
Guangwei Li

Completed

Contribution of Pancreatic αcells Function to Blood Glucose Regulation in Chinese Type 2 Diabetics- the Effect of Sitagliptin on Glucagon Secretion, Insulin Secretion and Insulin Resistance in Chinese Type 2 Diabetics

Insulin Resistance | Insulin Secretion

China
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

The Effect of Dipeptidyl Peptidase 4 Inhibition on Growth Hormone Secretion in Women With Polycystic Ovarian Syndrome

Polycystic Ovary Syndrome

United States
University Hospital, Gentofte, Copenhagen

Completed

Correlation Between Plasma- and Endothelial DPP-4 Activity

Type 2 Diabetes Mellitus

Denmark
Chinese PLA General Hospital

Completed

Prognostic Value of Plasma DPP4 Activity in ST-elevation Myocardial Infarction Patients

Coronary Angiography | Dipeptidyl Peptidase 4
Academisch Medisch Centrum - Universiteit van Amsterdam...
Merck Sharp & Dohme LLC

Completed

Dipeptidyl Peptidase-4 Inhibitors and Alpha-cell Recovery (DARE)

Hypoglycemia | Type 1 Diabetes

Netherlands
Long Min,MD

Unknown

Dipeptidyl Peptidase 4 Inhibition Facilitate Healing of Diabetic Ulcers (DPP4i)

Diabetic Foot Ulcer

China
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

A Study of DBPR108 and Metformin Hydrochloride Combination Therapy in Patients With T2DM

Type 2 Diabetes Mellitus

China
Washington University School of Medicine
The Campbell Foundation

Completed

Dipeptidyl Peptidase-4 Inhibition and Immune Function in HIV (DPPIVinHIV)

Diabetes | Insulin Resistance

United States
Fayoum University

Completed

Dipeptidyl Peptidase-4 Link With Oral Cancer and Premalignant Lesions

Oral Cancer | Oral Premalignant Lesions as Leukoplakia and Lichen Planus

Egypt
University of Athens

Unknown

The Association of Bullous Pemphigoid With Dipeptidyl-peptidase 4 Inhibitors

Bullous Pemphigoid

Greece
Lund University

Completed

Effects of Dipeptidyl Peptidase-4 (DPP-4) Inhibition on Hormonal Responses to Macronutrient Ingestion

Healthy | Type 2 Diabetes

Sweden
Changhua Christian Hospital

Completed

Comparing the Renal Effect of Dipeptidyl-peptidase 4 Inhibitors and Sulfonylureas

Type 2 Diabetes Mellitus | Proteinuria
Johns Hopkins University
Merck Sharp & Dohme LLC

Terminated

Dipeptidyl Peptidase-4 Inhibition on Glucagon-like Peptide-1 (GLP-1)

Glucose Homeostasis

United States
Astellas Pharma Inc

Completed

A Study to Assess the Safety and Efficacy of ASP1941 in Combination With Dipeptidyl Peptidase-4 (DPP-4) Inhibitor in Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

Japan
Institute for Clinical Effectiveness, Japan

Completed

Randomized Evaluation of Anagliptin Versus Sitagliptin On Low-density lipoproteiN Cholesterol in Diabetes Trial (REASON)

Coronary Disease | Diabetes Mellitus | Dipeptidyl-Peptidase 4 Inhibitors | LDL Cholesterol | Glycosylated Hemoglobin

Japan
Emory University
Merck Sharp & Dohme LLC

Completed

Dipeptidyl Peptidase-4 Inhibitor (Sitagliptin) Therapy in the Inpatients With Type 2 Diabetes

Hyperglycemia | Type 2 Diabetes Mellitus | Hospitalization

United States
The Catholic University of Korea
Merck Sharp & Dohme LLC

Completed

Pharmacokinetics Study of Dipeptidyl Peptidase 4 Inhibitor to Control Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Korea, Republic of
Kurume University

Unknown

Metabolic and Cardiovascular Effects of Dipeptidyl Peptidase-4 (DPP-4) or Sodium-glucose Co-transporter Type 2 (SGLT2) Inhibitors

Effects of the DPP-4 Inhibitors or SGLT2 Inhibitors on the Protective Actions for Diabetic Complications

Japan
Oregon Health and Science University

Suspended

Effects of DPP-4 Inhibition on Triglycerides

Type 2 Diabetes | Hypertriglyceridemia

United States
Ain Shams University

Completed

Effect of Dipeptidyl Peptidase- 4 Inhibitors on Non-Alcoholic Steatohepatitis and Type 1 Diabetes

Diabetes Mellitus, Type 1 | NASH

Egypt
University College Dublin

Completed

Dipeptidyl Peptidase-4 Inhibition and Narrow-band Ultraviolet-B Light in Psoriasis (DINUP) (DINUP)

Psoriasis

Ireland
Medical College of Wisconsin
Merck Sharp & Dohme LLC

Completed

Effects of Sitagliptin on Endothelial Function in Type 2 Diabetes on Background Metformin Therapy

Diabetes | Atherosclerosis

United States
Takeda

Completed

Treatment Preference for Weekly Dipeptidyl Peptidase-4 (DPP-4) Inhibitors Versus Daily DPP-4 Inhibitors in Participants With Type 2 Diabetes Mellitus (TRINITY)

Type 2 Diabetes Mellitus

Japan
Chinese PLA General Hospital

Unknown

Effects of a Dipeptidyl Peptidase-4 Inhibitor Sitagliptininsulin on the Progression of Coronary Atherosclerosis in Patients With Type 2 Diabetes

Atherosclerosis Type 2 Diabetes Mellitus Dipeptidyl Peptidase-4 Inhibitor GLP-1
Janssen Research & Development, LLC

Completed

Treatment Differences Between Canagliflozin and Placebo in Insulin Secretion in Subjects With Type 2 Diabetes Mellitus (T2DM)

Diabetes Mellitus, Type 2

United States
Rabin Medical Center

Terminated

Efficacy and Safety of Dipeptidyl Peptidase-4 Inhibitors in Diabetic Patients With Established COVID-19

Glucose Metabolism Disorders | Respiratory Tract Diseases | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Endocrine System Diseases | COVID 19 | Coronavirus | Metabolic Disease | Severe Acute Respiratory Syndrome Coronavirus 2 | Sars-CoV2 | Hormones | Hypoglycemic Agents | Incretins | Dipeptidyl-Peptidase IV Inhibitors and other conditions

Israel
Wuhan General Hospital of Guangzhou Military Command

Completed

Sitagliptin Reduces Left Ventricular Mass in Normotensive Type 2 Diabetic Patients With Coronary Artery Disease

Coronary Artery Disease | Newly Diagnosed Type 2 Diabetes

China
University College Dublin

Completed

Dipeptidyl Peptidase-4 Inhibition in Psoriasis Patients With Diabetes (DIP): A Randomized Clinical Trial. (DIP)

Type 2 Diabetes Mellitus | Psoriasis

Ireland
Hospital Regional de Alta Especialidad del Bajio

Completed

Dipeptidyl Peptidase-4 Inhibitor (DPP4i) for the Control of Hyperglycemia in Patients With COVID-19 (Covid19DPP4i)

Hyperglycemia | Covid19

Mexico
University Hospital, Gentofte, Copenhagen

Completed

Involvement of Dipeptidyl Peptidase-4 and Sodium-glucose Co-transporter-2 in Extrapancreatic Glucagon Secretion (Px-Meal)

Diabetes After Total Pancreatectomy

Denmark
AstraZeneca

Completed

Evaluate the Efficacy and Safety of Saxagliptin in Combination With Metformin IR Compared to Saxagliptin Monotherapy and to Metformin IR Monotherapy in Drug Naive Chinese Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control

Type 2 Diabetes Mellitus

China
Michael A. Nauck

Completed

Quantification of the Dipeptidyl Peptidase (DPP)-4 Inhibition-mediated Enhancement of the Activity of the Entero-insular Axis

Diabetes

Germany
University Medical Centre Ljubljana

Completed

Weight Maintenance With Dipeptidyl Peptidase 4 (DPP4) Inhibitor Sitagliptin in Combination With Metformin After Liragludite Induced Weight Loss

Polycystic Ovary Syndrome | Body Weight
University Hospital, Gentofte, Copenhagen
Eli Lilly and Company

Completed

The Role of Glucagon in the Effects of Dipeptidyl Peptidase-4 Inhibitors and Sodium-glucose Co-transporter-2 Inhibitors

Type 2 Diabetes

Denmark
Handok Inc.

Completed

Teneligliptin(MP-513) Versus Placebo in Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Korea, Republic of
Massachusetts General Hospital
GlaxoSmithKline

Terminated

Significance of Antibodies to Heparin/Platelet Factor 4 Complex in Vein Graft Patency and Potential Role of Argatroban for Prevention of Vein Graft Occlusion

Coronary Artery Bypass Graft Surgery | Presence of Heparin/Platelet Factor 4 Antibody

United States
AstraZeneca

Completed

Evaluate the Efficacy and Safety of Saxagliptin Added to Insulin Monotherapy or to Insulin Combined With Metformin in Chinese Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control

Type 2 Diabetes Mellitus

China
AstraZeneca
Eli Lilly and Company

Completed

Safety and Efficacy of Exenatide Once Weekly Injection Versus Metformin, Dipeptidyl Peptidase-4 Inhibitor, or Thiazolidinedione as Monotherapy in Drug-Naive Patients With Type 2 Diabetes (DURATION-4)

Type 2 Diabetes Mellitus

United States, Brazil, Italy, Korea, Republic of, Mexico, Poland, Russian Federation, Spain, Turkey, United Kingdom, South Africa, Argentina, Canada, Germany, Hungary, Israel, Romania, Slovakia, India, Belgium, France, Puerto Rico
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of Sitagliptin Compared With Glimepiride in Elderly Participants With Type 2 Diabetes Mellitus (MK-0431-251)

Type 2 Diabetes Mellitus
Maastricht Radiation Oncology
Maastricht University Medical Center

Withdrawn

Non-invasive Imaging With [18F]VM4-037 ([18F]VM4-037)

Stage 4 Cancer
Ajou University School of Medicine
Dong-A ST Co., Ltd.

Not yet recruiting

Effect of Dipeptidyl-4 Inhibitors in Reducing Stroke Severity, From HIRA Database

Cerebral Infarction | Dipeptidyl-Peptidase IV Inhibitors | Infarction, Brain
University Hospital, Basel, Switzerland

Completed

Effects of Exercise and Inhibition of Dipeptidyl Peptidase-4 on Insulin Secretion in Subjects With Type 1 Diabetes (EXTYPE-1)

Diabetes Mellitus Type 1

Switzerland
AstraZeneca
Parexel

Completed

Phase 1 Bioequivalence Study of Dapagliflozin/Sitagliptin FDC vs Loose Combination of Single Components

Healthy Volunteers (Intended Indication: Type 2 Diabetes Mellitus)

Germany
dr. DJ Mulder
Boehringer Ingelheim

Completed

Off taRget Effects of Linagliptin monothErapy on Arterial Stiffness in Early Diabetes (RELEASE)

Type 2 Diabetes Mellitus

Netherlands
California Institute of Renal Research

Recruiting

A Single Arm sTudy to Evaluate the Effectiveness of EndoAVF in a Pre-dialysis Population (STEP Study)

CKD Stage 4 | CKD Stage 5 | CKD Stage 3

United States
University Hospital, Gentofte, Copenhagen
University of Copenhagen

Unknown

Intact Vagal Innervation for and Glucagon-like Peptide-1 (GLP-1) Effects

Vagotomy, Truncal

Denmark
McGill University Health Centre/Research Institute...

Recruiting

Safety and Efficacy of Canagliflozin in Advanced CKD (SIP-AKiD)

ESRD | CKD Stage 4 | CKD Stage 5

Canada
Adienne SA
ADIENNE S.r.l. S.U.

Terminated

Study of BEGEDINA® vs "Conventional Treatment" for Treating Steroid-Resistant Acute GvHD

Graft vs Host Disease

United States, Spain, Italy, Germany, France, United Kingdom, Switzerland

Search clinical trials for: Kallikrein-related peptidase-4 (KLK4)

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