Search clinical trials for: LAL Deficiency

Total 10653 results

Cairo University

Recruiting

Vascularized Inter-positional Periosteal Connective-tissue Flap Versus Collagen Membrane in Guided Bone Regeneration (VIP-CT)

Horizontal Ridge Deficiency

Egypt
Alexion

Recruiting

Lysosomal Acid Lipase (LAL) Deficiency Registry (ALX-LALD-501)

Wolman Disease | Cholesterol Ester Storage Disease | Lysosomal Acid Lipase Deficiency | Acid Cholesteryl Ester Hydrolase Deficiency, Type 2 | Acid Lipase Deficiency | LIPA Deficiency | LAL-Deficiency

France, Belgium, United States, Spain, Germany, Greece, Israel, Italy, Slovenia, United Kingdom, Brazil, Canada, Denmark, Australia, Croatia, Czechia, Ireland, Mexico, Netherlands, Poland, Portugal, Saudi Arabia
ViiV Healthcare
Pfizer

Completed

Prospective Observational Epidemiologic Study of Maraviroc's Safety (POEM)

Human Immunodeficiency Virus

United States, Canada, Spain, Belgium, France, United Kingdom, Italy, Brazil, Puerto Rico, Germany, Greece
Alexion Pharmaceuticals

Completed

Acid Lipase Replacement Investigating Safety and Efficacy (ARISE) in Participants With Lysosomal Acid Lipase Deficiency (ARISE)

Lysosomal Acid Lipase Deficiency

France, Poland, United Kingdom, Spain, Mexico, Turkey, Japan, Australia, Russian Federation, United States, Germany, Italy, Czechia, Argentina, Croatia
Alexion Pharmaceuticals

Completed

Safety and Efficacy Study of Sebelipase Alfa in Participants With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency

Spain, Germany, Italy, United States, Croatia, Canada, Russian Federation, Denmark, United Kingdom, Belgium, Mexico, Australia, Netherlands, Brazil, Turkey
Alexion Pharmaceuticals

Terminated

Clinical Study In Infants With Rapidly Progressive Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency

United Kingdom, Finland, United States, Italy
Alexion Pharmaceuticals

Completed

Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of Sebelipase Alfa in Children With Growth Failure Due to Lysosomal Acid Lipase Deficiency

Wolman Disease | Lysosomal Acid Lipase Deficiency

United Kingdom, France, United States, Egypt, Ireland
Alexion Pharmaceuticals

Completed

Safety, Tolerability and Pharmacokinetics of SBC-102 (Sebelipase Alfa) in Adult Participants With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency | Cholesterol Ester Storage Disease(CESD) | LAL-Deficiency

France, United States, United Kingdom, Czechia
Alexion Pharmaceuticals

Completed

Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of SBC-102 (Sebelipase Alfa) in Adult Subjects With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency | LAL-Deficiency | Cholesterol Ester Storage Disease (CESD)

France, United Kingdom, United States, Canada, Czechia
Wellcome Trust Liverpool Glasgow Centre for Global...
Professor David Lalloo; Professor Hamish Simpson; Professor William J Harrison; Professor Sithombo Maqungo

Unknown

HIV in Orthopaedic Skeletal Trauma Study (HOST)

Fracture Healing in HIV-positive Patients

South Africa
Ankara University
Alexion Pharmaceuticals

Completed

National Lysosomal Acid Lipase Deficiency Study (LAL-D)

Cholesteryl Ester Storage Disease

Turkey
Alexion Pharmaceuticals

Terminated

Screening for Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency

United States
Hospices Civils de Lyon

Unknown

Assessment of the Prevalence of Lysosomal Acid Lipase Deficiency in Patients Waiting for a Liver Transplant. (LALTH-1)

Patients Waiting for a Liver Transplant.

France
Hospices Civils de Lyon

Unknown

Assessement of the Prevalence of Lysosomal Acid Lipase Deficiency in Liver Post-transplant Patients (LALTH-2)

Liver Post-transplant Patients

France
Alexion Pharmaceuticals

Completed

An Observational Study of Patients With Lysosomal Acid Lipase Deficiency/Cholesteryl Ester Storage Disease Phenotype

Lysosomal Acid Lipase Deficiency | Cholesterol Ester Storage Disease(CESD)

United States, United Kingdom, France, Canada, Czech Republic, Italy, Poland, Switzerland
Alexion

Completed

A Retrospective Natural History Study of Patients With Lysosomal Acid Lipase Deficiency/Wolman Phenotype

Wolman Disease | Lysosomal Acid Lipase Deficiency

United States, Canada, United Kingdom, Italy, France
Alexion Pharmaceuticals

No longer available

An Expanded Access Protocol for Sebelipase Alfa for Patients With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency
Alexion Pharmaceuticals

Terminated

A Study to Identify and Characterize LAL-D Patients in High-risk Populations

Lysosomal Acid Lipase Deficiency

United States
Azidus Brasil

Unknown

Evaluation of Pharmacokinetic and Pharmacodynamic Parameters of Somatropin Produced by Laboratory Blausiegel Indústria e Comércio Ltda., Compared to Saizen® From Laboratory Merck Serono S.A.

Growth Retardation | GH Deficiency (GHD)

Brazil
Azidus Brasil

Unknown

PHARMACODYNAMICS ASSESSMENT PRODUCT HEPARIN SODIUM (INTRAVENOUSLY) OF THE SWINE 5.000UI/ML OF BLAU FARMACÊUTICA S/A IN HEALTHY SUBJECTS IN COMPARISON OF SODIUM HEPARIN APP PHARMACEUTICALS

Healthy

Brazil
China-Japan Friendship Hospital

Recruiting

The Effects of Low-Dose Versus High-Dose Intravenous IRON Therapy with Ferric Derisomaltose in Patients with Chronic Heart Failure and Iron Deficiency (IRONDOSE)

Heart Failure | Iron Deficiency
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Not yet recruiting

PeLear CCC: Proyecto Latino Contra Cancer Colorectal (PeLear CCC)

Colorectal Cancer | Rectal Cancer | Rectal Neoplasms | Colon Cancer | Colon Adenocarcinoma | Colon Rectal Cancer | Hereditary Nonpolyposis Colon Cancer

United States
Cairo University

Not yet recruiting

Efficacy and Safety of Lactoferrin in Heart Failure Patients

Heart Failure With Reduced Ejection Fraction
University of Ulster
Northern Health & Social Care Trust (NHSCT); Solvotrin Therapeutics - Active...

Not yet recruiting

Adiposity and Iron Requirements in Pregnancy (ADIPREG)

Iron Deficiency Anemia of Pregnancy

United Kingdom
Uppsala University
University of Turku; Bielefeld University; Vivo international e.V.; The Swedish... and other collaborators

Not yet recruiting

Transforming Health and Resilience In Vulnerable Environments: Mental Health, Psychosocial Support, and Climate-Smart Farming in Nakivale (THRIVE)

Malnutrition | Psychological Distress | Mental Health | Malnutrition, Child | Dietary Deficiency
Belgian Research on AIDS and HIV Consortium

Not yet recruiting

Use of Long-Acting Injectable Cabotegravir/Rilpivirine for the Treatment of HIV in Belgium

Human Immunodeficiency Virus
Neurona Therapeutics

Not yet recruiting

Effect of NRTX-1001, a Cellular Therapy Product, for the Treatment of Refractory Bilateral TLE

Epilepsy, Temporal Lobe
Hospital Universitario 12 de Octubre

Not yet recruiting

Registry of Patients in Shock Treated With Vasopressin

Shock | Vasopressor Adverse Reaction | Vasopressin Causing Adverse Effects in Therapeutic Use | Vasopressin Deficiency

Spain
Rocket Pharmaceuticals Inc.

Not yet recruiting

Clinical Trial to Evaluate the Efficacy of Gene Therapy for Pyruvate Kinase Deficiency

Pyruvate Kinase Deficiency

Spain, United States
King's College Hospital NHS Trust
Chiesi Limited

Not yet recruiting

Less Invasive Surfactant Administration in Late Preterm or Early Term Born Infants

Respiratory Distress Syndrome | Surfactant Deficiency Syndrome Neonatal | Preterm Pregnancy
Essen Biotech

Not yet recruiting

Sequential CAR-T Cells Therapy for CD5/CD7 Positive T-cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma Using CD5/CD7-Specific CAR-T Cells (BAH246)

T Cell Lymphoma | T Cell Prolymphocytic Leukemia | T-cell Acute Lymphoblastic Leukemia | T Cell Leukemia | T-Cell Lymphoma of CNS | T Cell Childhood ALL

China
ANRS, Emerging Infectious Diseases

Not yet recruiting

Assisted Notification of Partners of Men Having Sex With Men Discovering Their Seropositivity (NotiVIH)

HIV Infections
Fundacja Nutricia
Institute of Mother and Child, Warsaw, Poland

Not yet recruiting

Polish Infants and Toddler Nutritional Study (PITNUTS)

Child | Nutritional Status | Children | Dietary Habits | Consumption | Diet, Healthy | Diet Habit | Nutritional Deficiency | Cross-sectional Study | Dietary Assessment | Macronutrients
IRCCS Ospedale San Raffaele

Not yet recruiting

Validation of Human Drugs Target of Repurposed Drugs and Novel Therapies

Rare Diseases | Corneal Neovascularization | Limbal Stem Cell Deficiency | Aniridia | Neurotrophic Keratopathy | Ocular Cicatricial Pemphigoid | Ocular Graft-versus-host Disease | EEC Syndrome
Raydiant Oximetry, Inc.
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Trans-Abdominal Fetal Pulse Oximetry - EFS-IDE

Oxygen Deficiency | Fetal Complications | Fetal Hypoxia | Fetal Conditions | Fetal Distress | Labor (Obstetrics)--Complications | Labor Fetal Anoxia

United States
Johns Hopkins University
National Institutes of Health (NIH); Desmond Tutu HIV Foundation

Not yet recruiting

Universal Test and Connect for HIV Service Delivery in South Africa (UTC-SA)

Human Immunodeficiency Virus | Emergency Department | Pre-Exposure Prophylaxis | South Africa
Assiut University

Not yet recruiting

Role of Perforator Flaps in Back Defects Reconstruction

Myelomeningocele
Wave Life Sciences Ltd.

Not yet recruiting

A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD (RestorAATion-2)

Alpha-1 Antitrypsin Deficiency
University of Zurich
Swiss HIV Cohort Study

Recruiting

Cabotegravir Plus Rilpivirine Long-acting Regimen in the Swiss HIV Cohort Study:Uptake, Outcome, and Risk Factors for Treatment Failures

HIV Infections

Switzerland
Dr. Lutfi Kirdar Kartal Training and Research Hospital

Recruiting

Comparison of Oxygen Reserve Index and Regional Cerebral Oxygen Saturation Indetermining Hypoxia in Obese Patients

Oxygen Deficiency

Turkey
Yonsei University

Recruiting

Effect of Non-anemic Iron Deficiency on Outcome Following Off-pump Coronary Revascularization

Coronary Artery Bypass, Off-Pump | Iron Deficiencies

Korea, Republic of
Maastricht University Medical Center

Not yet recruiting

Three Channel Food Concept: the Effect Meal Service on Food Intake During Hospitalization

Protein-Energy Malnutrition | Nutrition Poor

Netherlands
Sidney Kimmel Comprehensive Cancer Center at Johns...
Janssen Research & Development, LLC

Not yet recruiting

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Lymphoma | Multiple Myeloma | Hodgkin Lymphoma | Myelofibrosis | Non Hodgkin Lymphoma | Chronic Myeloid Leukemia | Hematologic Malignancy | Aplastic Anemia | Myelodysplastic Syndromes (MDS) | Acute Myeloid Leukemia (AML) | Bone Marrow Transplant Rejection | Acute Lymphoblastic Leukemia (ALL), Adult
Policlinico Hospital

Recruiting

Observational Study on the Variation of Ascorbic Acid in Patients Undergoing Solid Organ Transplantation (REDOX-TX)

Transplantation | Ascorbic Acid Deficiency

Italy
Vanderbilt University Medical Center
Aminu Kano Teaching Hospital

Not yet recruiting

Prevention of Malnutrition in Children With Sickle Cell Disease (PMC-SCD)

Malnutrition | Sickle Cell Disease
University Hospital, Clermont-Ferrand

Not yet recruiting

Interest of the Reborn® Doll as a TO in the Care of Residents With Alzheimer's Disease or a Related Disorder (PROTMA)

Dementia Alzheimers

France
United States Army Research Institute of Environmental...

Recruiting

Optimized Carbohydrate Fueling to Enhance Physical Performance During Energy Deficit

Energy Supply; Deficiency

United States
First People's Hospital of Hangzhou

Recruiting

Cangpo Liujun Prescription on Cancer-related Fatigue in Advanced Colorectal Cancer With Spleen Deficiency and Dampness Excess

Colorectal Cancer | Cancer-Related Fatigue

China
MetroHealth Medical Center
Kent State University

Not yet recruiting

Positive Peers Intervention Clinical Trial (PoPIT)

HIV Infections

United States
Beam Therapeutics Inc.

Not yet recruiting

A Study to Evaluate the Safety and Efficacy of BEAM-302 in Adult Patients With Alpha-1 Antitrypsin Deficiency (AATD)

Alpha 1-Antitrypsin Deficiency

United Kingdom

Search clinical trials for: LAL Deficiency

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