Search clinical trials for: LAL Deficiency

Total 10608 results

Cairo University

Recruiting

Vascularized Inter-positional Periosteal Connective-tissue Flap Versus Collagen Membrane in Guided Bone Regeneration (VIP-CT)

Horizontal Ridge Deficiency

Egypt
Alexion

Recruiting

Lysosomal Acid Lipase (LAL) Deficiency Registry (ALX-LALD-501)

Wolman Disease | Cholesterol Ester Storage Disease | Lysosomal Acid Lipase Deficiency | Acid Cholesteryl Ester Hydrolase Deficiency, Type 2 | Acid Lipase Deficiency | LIPA Deficiency | LAL-Deficiency

France, Belgium, United States, Spain, Germany, Greece, Israel, Italy, Slovenia, United Kingdom, Brazil, Canada, Denmark, Australia, Croatia, Czechia, Ireland, Mexico, Netherlands, Poland, Portugal, Saudi Arabia
ViiV Healthcare
Pfizer

Completed

Prospective Observational Epidemiologic Study of Maraviroc's Safety (POEM)

Human Immunodeficiency Virus

United States, Canada, Spain, Belgium, France, United Kingdom, Italy, Brazil, Puerto Rico, Germany, Greece
Alexion Pharmaceuticals

Completed

Acid Lipase Replacement Investigating Safety and Efficacy (ARISE) in Participants With Lysosomal Acid Lipase Deficiency (ARISE)

Lysosomal Acid Lipase Deficiency

France, Poland, United Kingdom, Spain, Mexico, Turkey, Japan, Australia, Russian Federation, United States, Germany, Italy, Czechia, Argentina, Croatia
Alexion Pharmaceuticals

Completed

Safety and Efficacy Study of Sebelipase Alfa in Participants With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency

Spain, Germany, Italy, United States, Croatia, Canada, Russian Federation, Denmark, United Kingdom, Belgium, Mexico, Australia, Netherlands, Brazil, Turkey
Alexion Pharmaceuticals

Terminated

Clinical Study In Infants With Rapidly Progressive Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency

United Kingdom, Finland, United States, Italy
Alexion Pharmaceuticals

Completed

Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of Sebelipase Alfa in Children With Growth Failure Due to Lysosomal Acid Lipase Deficiency

Wolman Disease | Lysosomal Acid Lipase Deficiency

United Kingdom, France, United States, Egypt, Ireland
Alexion Pharmaceuticals

Completed

Safety, Tolerability and Pharmacokinetics of SBC-102 (Sebelipase Alfa) in Adult Participants With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency | Cholesterol Ester Storage Disease(CESD) | LAL-Deficiency

France, United States, United Kingdom, Czechia
Alexion Pharmaceuticals

Completed

Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of SBC-102 (Sebelipase Alfa) in Adult Subjects With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency | LAL-Deficiency | Cholesterol Ester Storage Disease (CESD)

France, United Kingdom, United States, Canada, Czechia
Wellcome Trust Liverpool Glasgow Centre for Global...
Professor David Lalloo; Professor Hamish Simpson; Professor William J Harrison; Professor Sithombo Maqungo

Unknown

HIV in Orthopaedic Skeletal Trauma Study (HOST)

Fracture Healing in HIV-positive Patients

South Africa
Ankara University
Alexion Pharmaceuticals

Completed

National Lysosomal Acid Lipase Deficiency Study (LAL-D)

Cholesteryl Ester Storage Disease

Turkey
Alexion Pharmaceuticals

Terminated

Screening for Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency

United States
Hospices Civils de Lyon

Unknown

Assessment of the Prevalence of Lysosomal Acid Lipase Deficiency in Patients Waiting for a Liver Transplant. (LALTH-1)

Patients Waiting for a Liver Transplant.

France
Hospices Civils de Lyon

Unknown

Assessement of the Prevalence of Lysosomal Acid Lipase Deficiency in Liver Post-transplant Patients (LALTH-2)

Liver Post-transplant Patients

France
Alexion Pharmaceuticals

Completed

An Observational Study of Patients With Lysosomal Acid Lipase Deficiency/Cholesteryl Ester Storage Disease Phenotype

Lysosomal Acid Lipase Deficiency | Cholesterol Ester Storage Disease(CESD)

United States, United Kingdom, France, Canada, Czech Republic, Italy, Poland, Switzerland
Alexion

Completed

A Retrospective Natural History Study of Patients With Lysosomal Acid Lipase Deficiency/Wolman Phenotype

Wolman Disease | Lysosomal Acid Lipase Deficiency

United States, Canada, United Kingdom, Italy, France
Alexion Pharmaceuticals

No longer available

An Expanded Access Protocol for Sebelipase Alfa for Patients With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency
Alexion Pharmaceuticals

Terminated

A Study to Identify and Characterize LAL-D Patients in High-risk Populations

Lysosomal Acid Lipase Deficiency

United States
Azidus Brasil

Unknown

Evaluation of Pharmacokinetic and Pharmacodynamic Parameters of Somatropin Produced by Laboratory Blausiegel Indústria e Comércio Ltda., Compared to Saizen® From Laboratory Merck Serono S.A.

Growth Retardation | GH Deficiency (GHD)

Brazil
Azidus Brasil

Unknown

PHARMACODYNAMICS ASSESSMENT PRODUCT HEPARIN SODIUM (INTRAVENOUSLY) OF THE SWINE 5.000UI/ML OF BLAU FARMACÊUTICA S/A IN HEALTHY SUBJECTS IN COMPARISON OF SODIUM HEPARIN APP PHARMACEUTICALS

Healthy

Brazil
Beam Therapeutics Inc.

Not yet recruiting

A Study to Evaluate the Safety and Efficacy of BEAM-302 in Adult Patients With Alpha-1 Antitrypsin Deficiency (AATD)

Alpha 1-Antitrypsin Deficiency

United Kingdom
MetroHealth Medical Center
Kent State University

Not yet recruiting

Positive Peers Intervention Clinical Trial (PoPIT)

HIV Infections

United States
Mayo Clinic

Recruiting

Ultrasound Imaging and Quantitative Vibro-Acoustic Assessment of Rickets Under the Age of Ten

Rickets

United States
Changchun GeneScience Pharmaceutical Co., Ltd.

Not yet recruiting

A Bioavailability Study of Two Different PEG-rhGH Preparations.

Pediatric Growth Hormone Deficiency (PGHD)

China
Lallemand Health Solutions
BioFortis

Not yet recruiting

Effect of Probiotics on Infantile Colic Symptoms (EPIC)

Infantile Colic

France
Cordio Medical

Recruiting

AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM (DETECT-HF)

Heart Failure

United States, Israel
Shanghai Hutchison Pharmaceuticals Limited

Not yet recruiting

Efficacy and Safety of Shenqi Sherong Pill in Participants With Cervical Spondylotic Myelopathy

Cervical Spondylotic Myelopathy
Privatpraxis für Knie- und Schulterchirurgie

Recruiting

Sterile Allogeneic Spongioflex® Allograft as Partial Meniscal Replacement After Incomplete Meniscal Loss

Meniscus Lesion

Germany
L-Nutra Inc
University of Tennessee Medical Center

Recruiting

Fasting Mimicking Diet in Chemotherapy of Gynecologic Malignancies

Chemotherapy Effect | Fasting, Intermittent | Cancer, Ovarian | Calorie Deficiency

United States
Liaquat University of Medical & Health Sciences

Not yet recruiting

Assessing the Efficacy of Different Carrier Systems in Oral Vitamin B12 Supplementation in Healthy Adults With B12 Deficiency

Vitamin B 12 Deficiency

Pakistan
University of Missouri-Columbia
Gilead Sciences

Recruiting

Accelerated ART Initiation for PWHIV Who Are Out of Care (ACCELERATE)

HIV Infections | ART | Noncompliance, Patient

United States
McGill University Health Centre/Research Institute...

Not yet recruiting

The Antiretroviral Speed Access Program Switch (ASAP-Switch) Study

HIV Infections

Canada
Cairo University

Not yet recruiting

Relationship Between Vitamins Deficiency and Caries Experience Among a Group of Egyptian Children

Dental Caries | Vitamin Deficiency
Apollo Therapeutics Ltd

Not yet recruiting

A Study to Investigate APL-4098 Alone and/or in Combination With Azacitidine in R/R AML and High-Risk MDS

Myelodysplastic Syndrome With Excess Blasts | Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory | Myelodysplastic Syndrome Acute Myeloid Leukemia
Milton S. Hershey Medical Center

Not yet recruiting

Estrogen Deficiency on Cardiovascular Risk

Cardiovascular Diseases | Postmenopausal Symptoms
University of Stellenbosch
University College London Hospitals; University of Copenhagen; Imperial College... and other collaborators

Not yet recruiting

Harnessing Male Peer Networks to Enhance Engagement With HIV Prevention (IMPERATIVE)

HIV Infections
Linnaeus University
World Anti-Doping Agency; Swedish Research Council for Sport Science; Swedish...

Recruiting

Relative Energy Deficiency in Sports (REDs) in Swedish Athletes (REDs-Sweden)

Eating Disorders | RED S

Sweden
University of California, Los Angeles
University of North Carolina, Chapel Hill; University of California, Irvine; Florida... and other collaborators

Recruiting

Exploring, Predicting, and Intervening on Long-term Viral Suppression Electronically (EPI-LoVE)

HIV Infections

United States
ViiV Healthcare

Not yet recruiting

A Study to Investigate the Effect of Food on the Bioavailability of a Capsid Inhibitor (CAI) in Male and Female Healthy Participants

HIV Infections
bioLytical Laboratories

Not yet recruiting

A Study to Evaluate the Performance, Usability, and Result Interpretation of INSTI® HIV Self-Test

Human Immunodeficiency Virus I Infection | Human Immunodeficiency Virus II Infection
The Cooper Health System
Won Sook Chung Foundation

Not yet recruiting

Emulated Study of Vitamin D Correction vs Non-Correction

Vitamin D Deficiency
Arrowhead Regional Medical Center

Recruiting

Intravenous Iron Versus Oral Iron for the Treatment of Iron Deficiency Anemia (IDA)

Iron Deficiency Anemia of Pregnancy

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Phase Ib/II Trail of Neoadjuvant of Tislelizumab Combined With Palbociclib in Patients With Platinum-refractory Bladder Urothelial Carcinoma

Bladder Cancer

China
Ibrahim Halil Sahin
GlaxoSmithKline

Not yet recruiting

Niraparib and Dostarlimab for Patients With MMR-D/MSI-H Colorectal Cancers

MMR-D/MSI-H Colorectal Cancers

United States
Przemyslaw Kunert
NaoX Technologies; Warsaw Medical University Clinical Center; Departments and...

Not yet recruiting

Assessment of Patients With Drug-resistant Temporal Lobe Epilepsy With EEG Extended With Intra-auricular Electrodes

Epilepsy | Drug Resistant Epilepsy | Focal Epilepsy

Poland
McGill University
Global Affairs Canada; World Vision Canada

Not yet recruiting

Evaluation of REACTS-IN, an Intervention to Improve Nutrition, Hygiene, and Sexual and Reproductive Health Services (REACTS-IN)

Stunting | Diet; Deficiency | Empowerment | Acceptability of Health Care | Gender Equality

Bangladesh, Kenya, Tanzania
Octapharma

Not yet recruiting

Phase 3 Study of IV Human Plasma-derived C1 Esterase Inhibitor Concentrate in Patients With Congenital C1-INH Deficiency for Treatment and Pre-procedure Preventing of Acute Hereditary Angioedema Attacks

Acute Hereditary Angio Edema
7 Hills Pharma, LLC

Not yet recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

Melanoma | Kidney Cancer | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | NSCLC | Non Small Cell Lung Cancer | Skin Cancer | Metastasis | Advanced Solid Tumor | Advanced Cancer | Renal Cell Cancer | Hepatocellular Cancer | Mismatch Repair Deficiency | Pleural Mesothelioma | MSI-High | Anaplastic Lymphoma... and other conditions

United States
Federation Francophone de Cancerologie Digestive

Recruiting

Prospective Cohort Study of Immunotherapy Resistance in Metastatic Colorectal Cancer Patients With MSI (CORESIM)

Colorectal Cancer Metastatic | Microsatellite Instability-High Colorectal Cancer

France
University of California, San Francisco
Gilead Sciences

Not yet recruiting

Community-based, Peer-delivered PrEP for Female Sex Workers in Rural Uganda: The Peers for PrEP (P4P) Study (P4P)

HIV/AIDS

Uganda

Search clinical trials for: LAL Deficiency

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