Search clinical trials for: Lamin Type A

Total 491545 results

Tongji Hospital
Wuhan University; Wuhan Central Hospital; Wuhan Fourth Hospital

Recruiting

The Effects of Sirolimus in Patients With Dilated Cardiomyopathy Infected With Kaposi Sarcoma-associated Virus (SDCMK)

Dilated Cardiomyopathy | Kaposi's Sarcoma-Associated Herpesvirus Infection

China
Pfizer

Recruiting

A Study About the Natural History in Adults With BAG3 Dilated Cardiomyopathy (a Type of Heart Disease) (BAG3 DCM)

Cardiomyopathy, Dilated | Bcl-2 Anathogene-3 (BAG3) Dilated Cardiomyopathy (DCM)

United States, Spain, Netherlands, Poland, United Kingdom
Institut National de la Santé Et de la Recherche...

Recruiting

Modifying Factors in Striated Muscle Laminopathies (LMNAModifier)

Laminopathies | Emery Dreifuss Muscular Dystrophy 2 | LMNA-Related Congenital Muscular Dystrophy | Dilated Cardiomyopathy-1A

France
Cristina Avendaño Solá

Recruiting

Early Treatment With Candesartan vs Placebo in Genetic Carriers of Dilated Cardiomyopathy (EARLY-GENE Trial) (EARLY-GENE)

Cardiomyopathy, Dilated

Spain
University Hospital, Lille

Recruiting

Study of Cortisol Metabolism in Familial Partial Lipodystrophy Type 2 (LIPOCORT)

Familial Partial Lipodystrophy Type 2

France
Laminar Pharmaceuticals
Dana-Farber Cancer Institute; Hackensack Meridian Health; Laminar Pharma Inc

Recruiting

Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors

High-grade Glioma | Solid Tumor, Unspecified, Child

United States
Laminar Pharmaceuticals
Laboratory Corporation of America; Northern Institute for Cancer Research,... and other collaborators

Recruiting

LAM561 With RT and TMZ for Adults With Glioblastoma (CLINGLIO)

Glioblastoma Multiforme | Primary Glioblastoma

Spain, Italy, United Kingdom, France, Israel
City of Hope Medical Center
University of California, Los Angeles

Recruiting

Improving Islet Transplantation Outcomes With Gastrin for Type I Diabetes

Diabetes Mellitus, Type 1

United States
Sanford Health
National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions

United States, Australia
Pfizer

Completed

A Study To Evaluate The Pharmacokinetics, Excretion, Mass Balance and Metabolism of PF-07265803

Healthy

United States
Pfizer

Terminated

A Study of ARRY-371797 (PF-07265803) in Patients With Symptomatic Dilated Cardiomyopathy Due to a Lamin A/C Gene Mutation (REALM-DCM)

Dilated Cardiomyopathy | Lamin A/C Gene Mutation

United States, Spain, Canada, Belgium, Italy, Argentina, Mexico, Netherlands, Norway, United Kingdom
University Hospital Bispebjerg and Frederiksberg
University Hospital Bispebjerg and Frederiksberg, Søren Overgaard, Professor... and other collaborators

Completed

Does the Type of Ventilation Affect the Risk for Infections After Hip Replacements?

Hip Prosthesis Infection
Boston Children's Hospital

Enrolling by invitation

Phase I/II Trial of Everolimus in Combination With Lonafarnib in Progeria

Progeria

United States
Laminar Pharmaceuticals
Royal Marsden NHS Foundation Trust; Vall d'Hebron Institute of Oncology; Specialized... and other collaborators

Completed

A Phase 1/2A Study of LAM561 in Adult Patients With Advanced Solid Tumours

Glioma | Other Solid Tumours

Spain, United Kingdom
Laminar Pharmaceuticals

Completed

A Study to Evaluate the Safety of LAM561 Added to Standard of Care in Newly-diagnosed Glioblastoma Patients

Glioblastoma (GBM)

Spain
Akcea Therapeutics
Ionis Pharmaceuticals, Inc.

Completed

Study of AKCEA-ANGPTL3-LRx (ISIS 703802) in Participants With Familial Partial Lipodystrophy (FPL)

Familial Partial Lipodystrophy

United States
Acrotech Biopharma Inc.

Withdrawn

Phase 1 Study of Fusilev to Prevent or Reduce Mucositis in Patients With Non-Hodgkin's Lymphoma Receiving Folotyn

Non Hodgkin's Lymphoma
Azienda Ospedaliero, Universitaria Pisana

Unknown

Myocardial Metabolism in Patients With Dilated Cardiomyopathy

Type 2 Diabetes | Dilated Cardiomyopathy

Italy
Xijing Hospital

Completed

Supramaximal Titrated Inhibition of RAAS in Dilated Cardiomyopathy

Dilated Cardiomyopathy

China
Maastricht University Medical Center
Center for Translational Molecular Medicine

Completed

Cross-over Study on Effect of Lipid Lowering by Acipimox on Cardiac and Skeletal Muscle Mitochondrial Function (ACP)

Diabetes Mellitus, Type 2 | Cardiomyopathy, Dilated

Netherlands
Samsung Medical Center

Unknown

Hemostatic Effect of Various Colloid Solutions

Laminectomy

Korea, Republic of
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

Efficacy and Safety of MTBF Conditioning Regimen for Salvageable Allo-HSCT in the Treatment of R/R AML

Refractory Acute Myeloid Leukemia | Conditioning | Hematopoietic Stem Cell Transplantation | Relapse Leukemia
Assembly Biosciences

Not yet recruiting

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital Herpes

Recurrent Genital Herpes Simplex Type 2

New Zealand
Central Hospital, Nancy, France

Not yet recruiting

Strategy to Adapt Botulinum Toxin Doses in Dystonia

Dystonia
Mayo Clinic

Not yet recruiting

Reduced Dose Radiotherapy for the Treatment of Indolent Non-Hodgkin Lymphoma

Indolent B-Cell Non-Hodgkin Lymphoma | Recurrent Indolent Non-Hodgkin Lymphoma | Refractory Indolent Non-Hodgkin Lymphoma | Recurrent Indolent B-Cell Non-Hodgkin Lymphoma | Refractory Indolent B-Cell Non-Hodgkin Lymphoma

United States
Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Chidamide, Venetoclax, and Azacitidine for Newly Diagnosed Acute Myeloid Leukemia

Acute Myeloid Leukemia | AML
Hutchmed

Not yet recruiting

A Study to Evaluate HMPL-306 in Patients With IDH1- and IDH2-mutated Acute Myeloid Leukemia

Acute Myeloid Leukemia
Diabetes Foundation, India
National Diabetes Obesity and Cholesterol Foundation

Recruiting

Comparison of Micro- and Macrovascular Disease(s) in People With T2D, Who Have Moderate to Severe Acanthosis Nigricans vs. Those Who do Not Have Acanthosis Nigricans

Type 2 Diabetes Mellitus With Complication

India
University of Reading

Recruiting

The Effects of Raspberry Leaf Tea on Blood Glucose Control (RLT)

Type II Diabetes

United Kingdom
McGill University Health Centre/Research Institute...

Not yet recruiting

Alleviating Carbohydrate Counting for Patients With Type-1 Diabetes Using a Closed Loop System With Weekly Subcutaneous Semaglutide (SEMA SMA)

Diabetes Mellitus | Type 1 Diabetes

Canada
Shanghai Chest Hospital

Not yet recruiting

Neoadjuvant PD-1 Blockade for Elderly Esophageal Squamous Cell Carcinoma (BLESS) (BLESS)

Esophageal Cancer

China
Peking University First Hospital

Recruiting

PET Imaging Study of 68Ga-NB381 in Multiple Myeloma

Multiple Myeloma

China
Case Comprehensive Cancer Center

Not yet recruiting

Fasting During Neoadjuvant Chemotherapy in Patient With Epithelial Ovarian Cancer

Epithelial Ovarian Cancer
Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Elderly/Unfit Ph- B-ALL

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Boston Immune Technologies and Therapeutics

Not yet recruiting

A Clinical Trial in Adults With Non-Hodgkin Lymphoma (NHL), With a Particular Emphasis on Cutaneous T Cell Lymphoma (CTCL), Testing the Safety and Activity of a Novel Drug to Inhibit a Protein Called Tumor Necrosis Factor Receptor 2 That Drives Both Lymphoma Growth and Escape of the Immune System

Peripheral T-cell Lymphoma | NHL | Cutaneous T Cell Lymphoma
Henan University of Traditional Chinese Medicine

Recruiting

Lifei Xiaoji Wan Treatment's of Early-stage NSCLC and Its Impact on the Tumor Microenvironment

Early Stage Lung Adenocarcinoma

China
Chong Kun Dang Pharmaceutical

Not yet recruiting

A Clinical Trial to Evaluate the Food Effect of CKD-378

Type II Diabetes Mellitus
Wang Siqi
China-Japan Friendship Hospital

Not yet recruiting

Research on Changes in Intestinal Barrier Function and Gut Microbiome in Patients With Type 2 Diabetes After Duodenal Mucosal Resurfacing (DMR) (DMR-IBF-GM)

Diabetes Mellitus, Type 2
University Hospital Tuebingen

Recruiting

Blood and Tissue Extraction for Immunological Examinations During Neoadjuvant Therapy of Soft Tissue Sarcomas

Soft Tissue Sarcoma Adult

Germany
Diabetes Foundation, India
National Diabetes Obesity and Cholesterol Foundation

Recruiting

To Compare People With T2DM Who Have Double Hump Versus Who do Not Have Double Hump

Type 2 Diabetes Mellitus With Complication

India
Wuhan Union Hospital, China

Recruiting

Study on the Clinical Application Value of PET Imaging Targeting GPC3 in Hepatocellular Carcinoma

Malignant Neoplasm of Liver

China
Global Aesthetics LLC

Not yet recruiting

Assessing the Impact of Botulinum Toxin Type A on Facial Wrinkles: A Comprehensive Clinical Investigation

Wrinkle

United States
Oregon State University
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Shift Worker Intervention for Sleep Health (SWISH)

Insomnia, Psychophysiological | Shift Work Type Circadian Rhythm Sleep Disorder

United States
OncoVerity, Inc.

Not yet recruiting

A Study Comparing Venetoclax and Azacitidine Plus Cusatuzumab to Venetoclax and Azacitidine in Newly Diagnosed AML Ineligible for Intensive Therapy

Leukemia, Myeloid, Acute
Renee Cattell

Not yet recruiting

Raman Spectroscopy and Skin Cancer

Skin Cancer | Basal Cell Carcinoma | Squamous Cell Carcinoma

United States
The First Affiliated Hospital of Guangzhou Medical...

Recruiting

Osimertinib as Neoadjuvant Therapy in Patients With Resectable Stage II-IIIB EGFR-mutated Lung Squamous Cell Carcinoma (GALAXY-02)

Carcinoma, Squamous Cell | Lung Cancer

China
Regeneron Pharmaceuticals

Not yet recruiting

Study of Cemiplimab Alone or in Combination With Fianlimab and/or Other Experimental Agents in Adult Participants With Peri-operative Stage III/IV Cutaneous Squamous Cell Carcinoma (CSCC)

Cutaneous Squamous Cell Carcinoma
Janssen Research & Development, LLC

Recruiting

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Recurrent/Metastatic Head and Neck Cancer (OrigAMI-4)

Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

United States
IRCCS Policlinico S. Matteo

Recruiting

Promoting Diagnosis and Management of AL in Italy (ProDigALIty) (ProDigALIty)

AL Amyloidosis | Monoclonal Gammopathy of Undetermined Significance | Smoldering Multiple Myeloma

Italy
The University of Texas Health Science Center at...

Not yet recruiting

Lifestyle MIND- Feasibility for Randomized Wait-list Control Trial (MIND)

Schizophrenia | Type 2 Diabetes Mellitus | Bipolar Disorder | Major Depression | Serious Mental Illness

United States

Search clinical trials for: Lamin Type A

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