Search clinical trials for: Loss of Ataxia Telangiectasia Mutated (ATM) protein

Total 430123 results

University College Dublin
University of Padova; Institut National de Recherche pour l'Agriculture, l'Alimentation... and other collaborators

Completed

Determination of In-vivo Plasma AA Appearance From Plant Protein Fibre Products

Aging | Undernutrition | Appetite Loss | Age-Related Sarcopenia

Ireland, Italy
University Hospital, Akershus
Oslo University Hospital; University Hospital of North Norway; University of... and other collaborators

Active, not recruiting

NAD Supplementation to Prevent Progressive Neurological Disease in Ataxia Telangiectasia

Ataxia Telangiectasia

Norway
Intergroupe Francophone de Cancerologie Thoracique

Completed

Combination of Cetuximab With Afatinib for Patient With EGFR Mutated Lung Cancer (ACE-Lung)

Non Small Cell Lung Cancer

France
Federal Research Institute of Pediatric Hematology...

Completed

Videoocular Assessment of Eye Movement Activity in an Ataxia Telangiectasia

Ataxia Telangiectasia | Dysmetria

Russian Federation
Ariad Pharmaceuticals

Completed

A Study of Ponatinib in Japanese Participants With Chronic Myeloid Leukemia (CML) and Ph+ Acute Lymphoblastic Leukemia (ALL)

Chronic Myeloid Leukemia (CML) | Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL)

Japan
United States Army Research Institute of Environmental...
University of Arkansas; Norwegian Defense Research Establishment

Completed

Physiological Response to Protein and Energy-enhanced Food Products During Winter Military Training

Weight Loss | Military Operational Stress Reaction | Malnutrition (Calorie) | Muscle Wasting

Norway
Veena Ranganath, MD, MS

Completed

Ultrasound Assessment of Rheumatoid Arthritis Patients Who Changed Diet

Overweight | Rheumatoid Arthritis

United States
University of Alabama at Birmingham

Completed

Comparing High and Normal Protein Diets for the Dietary Remission of Type 2 Diabetes

Obesity | Diet Modification | Diabetes Type 2

United States
Sanofi

Completed

Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (FRC) Versus GLP-1 Receptor Agonist in Patients With Type 2 Diabetes, With a FRC Extension Period (LixiLan-G)

Type 2 Diabetes Mellitus

Estonia, Italy, Israel, United States, Canada, Germany, Romania, Slovakia, Spain
Rutgers University
National Institute on Aging (NIA)

Terminated

The Effect of Severe Weight Loss and Protein Intake on Bone

Weight Loss

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); GlaxoSmithKline; Merck Sharp & Dohme LLC; Nova...

Completed

BATTLE-2 Program: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small Cell Lung Cancer

Lung Cancer

United States
University of Bergen

Completed

A Study on the Effects on Glucose Regulation, Inflammation and Serum Lipids After Fish Protein Supplementation in Elderly (GRIPE) (GRIPE)

Inflammation | Muscle Weakness | Aging | Muscle Loss | Blood Sugar; High
University of Zurich

Completed

Lateral Ridge Augmentation Using Autogenous Bone Blocks or Xenogenic Bone Block Grafts Loaded With Recombinant Human Bone Morphogenic Protein 2

Missing Teeth

Switzerland, Austria
University College, London
NIHR UCLH BRC; The Bernice Bibby Research Trust

Completed

Audiovestibular Function in Infratentorial Superficial Siderosis (AViSS)

Rare Diseases | Siderosis | Presbycusis | Neurological Disorder | Age Related Hearing Loss

United Kingdom
University of Copenhagen
US National Cattlemen´s Association; Danish Agriculture and Food Counsel

Completed

The Effect of High vs. Moderate Protein Consumption on Human Health (BEEF)

Obesity | Weight Loss | Metabolism and Nutrition Disorder

Denmark
University of Nottingham
Nottingham University Hospitals NHS Trust; Royal Papworth Hospital

Active, not recruiting

A National Retrospective Population Based Cohort Study of the Natural History of Ataxia Telangiectasia (N-HAT)

Ataxia Telangiectasia

United Kingdom
Massachusetts Eye and Ear Infirmary
Ohio State University; University of Geneva, Switzerland

Completed

Vestibular Implants Tested in Human Subjects

Vestibular Disorder | Vestibular Ataxia | Vestibular Loss, Bilateral

United States, Switzerland
AstraZeneca

Completed

Efficacy and Safety of Osimertinib for HK Chinese With Metastatic T790M Mutated NSCLC-real World Setting.

Non-small Cell Lung Cancer

China
Johann Wolfgang Goethe University Hospital

Completed

Oxidative Stress, Low Grade Inflammation, Tissue Breakdown and Biomarkers in Cerebrospinal Fluid of A-T

Ataxia Telangiectasia

Germany
University College, London

Completed

Randomised Trial in Waldenstrom's Macroglobulinaemia (R2W)

Waldenstrom's Macroglobulinaemia

United Kingdom
Siddhartha Ganguly

Completed

Exploratory Trial to Estimate Proportion of Patients With Tumor Cell Contaminated Leukapheresis Products With and Without Bortezomib With In-vivo Purging - Multiple Myeloma (MM)

Multiple Myeloma

United States
University Hospital, Geneva

Completed

Microbiota and Protein-energy Wasting (MIDIWA) (MIDIWA)

Undernutrition

Switzerland
Astellas Pharma Global Development, Inc.

Approved for marketing

Expanded Access Study of Gilteritinib (ASP2215) in Patients With FMS-like Tyrosine Kinase 3 (FLT3) Mutated Relapsed or Refractory Acute Myeloid Leukemia (AML) or FLT3-Mutated AML in Complete Remission (CR) With Minimal Residual Disease (MRD)

Acute Myeloid Leukemia (AML) | FMS-like Tyrosine Kinase-3 (FLT3) Mutations

United States, Canada, Japan
Novartis Pharmaceuticals

Completed

A Safety and Efficacy Study of INC280 and Gefitinib in Patients With EGFR Mutated, c-MET-amplified NSCLC Who Have Progressed After EGFRi Treatment

Non-small Cell Lung Cancer

China, Taiwan, Belgium, Netherlands, Spain, Germany, Singapore, Italy, Japan, Australia, Israel, Korea, Republic of, Thailand, France
Amsterdam UMC, location VUmc

Terminated

Iressa Re-challenge in Advanced NSCLC EGFR-mutated Patients (IRENE)

Lung Cancer

Netherlands
Novartis Pharmaceuticals

Completed

Standard of Care +/- Midostaurin to Prevent Relapse Post Stem Cell Transplant in Patients With FLT3-ITD Mutated AML (RADIUS)

Acute Myeloid Leukemia

United States, Canada
AbbVie

Completed

Observational Study Evaluating the Effectiveness of Drug Concentration to Predict the Recapture of Response in Crohn's Disease Patients With Loss of Response ( PRADA ) (PRADA)

Crohn's Disease

Canada
Bristol-Myers Squibb

Completed

Pilot Study to Evaluate the Safety and Efficacy of Abatacept in Adults and Children 6 Years and Older With Excessive Loss of Protein in the Urine Due to Either Focal Segmental Glomerulosclerosis (FSGS) or Minimal Change Disease (MCD)

Focal Segmental Glomerulosclerosis | Nephrotic Syndrome | Minimal Change Disease

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Alone or With Radiation Therapy in Treating Children With Kidney Cancer

Kidney Cancer

United States, Canada, Puerto Rico, Australia, Netherlands, New Zealand, Switzerland
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia

Fatigue | Anemia | Weight Loss | Thrombocytopenia | Fever | Refractory Plasma Cell Myeloma | Lymphadenopathy | Refractory Chronic Lymphocytic Leukemia | Recurrent Plasma Cell Myeloma | Splenomegaly | Recurrent Chronic Lymphocytic Leukemia | Lymphocytosis | Night Sweats

United States
Oxford University Hospitals NHS Trust
Amgen

Completed

The Development and Pilot Testing of a New MR Imaging Protocol to Quantify Myeloma Disease Burden and Bone Loss (LOOMIS)

Myeloma | Smouldering Myeloma | Monoclonal Gammopathy of Undetermined Significance (MGUS)

United Kingdom
KU Leuven

Completed

Effects of Ketones on Muscle Wasting During Caloric Restriction in Lean Females

Ketosis | Protein Intake | Muscle Wasting | Caloric Restriction

Belgium
Universitat Politècnica de Catalunya
University of Barcelona; Clinica Dorsia

Completed

Effectiveness of the Mediterranean Diet on Weight Loss After Endoscopic Bariatric Treatmen

Obesity | Obesity, Morbid
Sichuan Provincial People's Hospital

Terminated

Stereotactic Body Radiation Therapy (SBRT) in Newly Diagnosed Advanced Staged Lung Adenocarcinoma (Sindas) (Sindas)

Stage IV EGFR Mutated Non-Small Cell Lung Cancer

China
Ariad Pharmaceuticals

Completed

Ponatinib for Chronic Myeloid Leukemia (CML) Evaluation and Ph+ Acute Lymphoblastic Leukemia (ALL) (PACE)

Chronic Myeloid Leukemia | Ph+ Acute Lymphoblastic Leukemia

France, Belgium, Australia, Singapore, Germany, Spain, United Kingdom, Netherlands, Italy, Korea, Republic of, Sweden
Bispebjerg Hospital
University of Copenhagen; University of Aarhus; The Danish Dairy Research Foundation... and other collaborators

Completed

Cut Down on Carbohydrate Usage in the Diet of Type 2 Diabetes. The Hypo-energetic Study (CutDM-Hypo)

Diabetes Mellitus, Type 2 | Overweight and Obesity

Denmark
VA Office of Research and Development

Completed

Exercise to Prevent Muscle Mass and Functional Loss in Elderly Dialysis Patients (PERFECT)

Chronic Kidney Disease

United States
Jens Rikardt Andersen
Department of Oncology, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen

Unknown

EPA Supplementation in Cancer Patients Receiving Abdominal Radiotherapy -

Weight Loss | Abdominal Cancer | Radiotherapy; Complications | Protein Deficiency | Energy Supply

Denmark
Novartis Pharmaceuticals

Completed

PI3K Inhibitor BYL719 in Combination With the HSP90 Inhibitor AUY922 in Patients With Advanced or Metastatic Gastric Cancer

Stomach Neoplasms Esophageal Neoplasms Metastatic Gastric Cancer Mutated PI3KCA Protein Overexpressed HER2 Protein

Taiwan, Switzerland, Korea, Republic of, Germany, United States, Japan
Johann Wolfgang Goethe University Hospital

Unknown

Neurofilament Light- Chain in Ataxia Telangiectasia

Ataxia Telangiectasia

Germany
AVEO Pharmaceuticals, Inc.
Biodesix, Inc.

Terminated

A Phase 2, Study of Ficlatuzumab Plus Erlotinib vs. Placebo Plus Erlotinib in Subjects With Previously Untreated Metastatic, EGFR-mutated NSCLC and BDX004 Positive Label (FOCAL)

Non-small Cell Lung Cancer

Korea, Republic of, United States, Australia, Taiwan, Singapore, Hong Kong, Italy
Seoul National University Hospital
Seoul National University Bundang Hospital

Unknown

Efficacy of Protein Supplemented Very Low Calorie Meals on Weight Loss

Obesity | Sarcopenic Obesity

Korea, Republic of
West Cancer Center
Amgen; University of Tennessee Health Science Center

Unknown

Combining Talimogene Laherparepvec With BRAF and MEK Inhibitors in BRAF Mutated Advanced Melanoma

Melanoma | BRAF Gene Mutation

United States
Tulane University
Ideal Protein

Completed

A Trial of the Ideal Protein System Versus Low Fat Diet for Weight Loss (RENEWAL)

Weight Loss

United States
Technische Universität Dresden
Novartis Pharmaceuticals

Completed

Trial to Assess the Efficacy of Midostaurin (PKC412) in Patients With c-KIT or FLT3-ITD Mutated t(8;21) AML (MIDOKIT)

Acute Myeloid Leukemia

Germany
Hospital de Clinicas de Porto Alegre
Conselho Nacional de Desenvolvimento Científico e Tecnológico; Brazilian National...

Completed

Effects of High Protein Diet on Muscle Mass, Strength, and Physical Performance in Postmenopausal Women

Physical Disability | Muscle Loss
Kanuni Sultan Suleyman Training and Research Hospital

Completed

Evaluation of Endoplasmic Reticulum Stress in Patients With Recurrent Pregnancy Loss

Recurrent Pregnancy Loss | Endoplasmic Reticulum Stress

Turkey
Novartis Pharmaceuticals

No longer available

Midostaurin Access Program for Newly Diagnosed FLT3 (ITD or TKD) Mutated AML Adult Patients Eligible for Standard Induction and Consolidation Chemotherapy (AMLFLT3)

Acute Myeloid Leukemia (AML) With | FLT3 Mutation, Internal Tandem Duplication (ITD) or Tyrosine Kinase Domain (TKD)

United States
University of Aarhus
Aarhus University Hospital; Arla Foods Ingredients

Completed

Anabolic Potential of 3-hydroxybutyrate (3-OHB) and Whey Protein in a Human Catabolic Inflammatory Disease Model

Endotoxemia | Muscle Loss | Nutrition Therapy | Protein; Disease | Catabolic State

Denmark
University of Birmingham
University of Nottingham; Biotechnology and Biological Sciences Research Council

Completed

Preventing Bed-rest Induced Muscle Loss in the Elderly

Sarcopenia | Muscle Loss | Prehabilitation | Disuse Atrophy | Protein Metabolism

United Kingdom

Search clinical trials for: Loss of Ataxia Telangiectasia Mutated (ATM) protein

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