Search clinical trials for: MRD-

Total 245 results

Cancer Institute and Hospital, Chinese Academy...
Beijing Huanxing Cancer Hospital; Cancer Hospital, Chinese Academy of Medical...

Recruiting

Adopting the MRD Strategy to Optimize Post-operation Adjuvant Therapies for Early Stage Breast Cancer (AMENDER)

Early-stage Breast Cancer

China
AstraZeneca

Completed

Phase III Study to Determine the Efficacy of Durvalumab in Combination With Chemotherapy in Completely Resected Stage II-III Non-small Cell Lung Cancer (NSCLC) (MERMAID-1)

Carcinoma, Non-Small-Cell Lung

United States, Canada, Denmark, France, Netherlands, Belgium, Poland, Taiwan, Thailand, Vietnam, Italy, Korea, Republic of, Brazil, Czechia, Hungary, Japan, Russian Federation, Germany, Hong Kong, Spain, Greece, Switzerland, Australia, Isra... and more
The First Hospital of Jilin University
Geneplus-Beijing Co. Ltd.

Recruiting

Exploring the Potential of ctDNA-MRD for Recurrence Surveillance and Prognostic Evaluation in High-risk Endometrial Cancer

Endometrial Cancer

China
Xianmin Song, MD

Recruiting

Next Generation Sequencing（NGS）Monitors Minimal Residual Disease（MRD）in Allo-PBSCT Patients

NGS Monitor MRD

China
University of Michigan
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Development of a Multifunctional Rehabilitation Device for Persons With Parkinson's Disease

Parkinson Disease

United States
Exact Sciences Corporation
Labcorp Corporation of America Holdings, Inc

Recruiting

First CORRECT Study of Minimal Residual Disease (MRD) Detection in Colorectal Cancer (MRD)

Colorectal Cancer

United Kingdom, Spain, Italy, Israel
University of Texas Southwestern Medical Center

Not yet recruiting

Clinical Performance Evaluation of the C2i Test

Muscle Invasive Bladder Cancer
University of Zurich

Completed

Seated Evaluation of Anorectal funcTion by High Resolution Anorectal Manometry (SEAT)

Incontinence | Anismus

Switzerland
Exact Sciences Corporation
NSABP Foundation Inc

Recruiting

CORRECT Study of Minimal Residual Disease Detection in Colorectal Cancer (MRD)

Colorectal Cancer

United States
University of Kansas

Recruiting

HIFT for People With Mobility-Related Disabilities (Research GO)

Physical Disability | Mobility Limitation

United States
Northern Italy Leukemia Group
Associazione Italiana per la Ricerca sul Cancro

Completed

Treatment of Adult ALL With an MRD-directed Programme.

Acute Lymphoblastic Leukemia

Italy
Second Xiangya Hospital of Central South University
Geneplus-Beijing Co. Ltd.

Not yet recruiting

ctDNA-MRD in Stage IIIB-C NSCLC Patients Treated With Induction Chemoimmunotherapy

Non-small Cell Lung Cancer

China
Rajshekhar Chakraborty, MD
Hope Foundation

Recruiting

Non-invasive MRD Assessment in Multiple Myeloma (NIRVANA)

Myeloma

United States
WeiWei Xiao
Haplox Biotechnology Co., Ltd.

Recruiting

Predicting the Efficacy and Prognosis of Rectal Cancer Patients Based on ctDNA-MRD Technology

Minimal Residual Disease | Circulating Tumor DNA | Rectal Adenocarcinoma | Neoadjuvant Chemoradiotherapy

China
BAIYONG SHEN
GeneCast Biotechnology Co., Ltd.

Not yet recruiting

ctDNA-based Minimal Residual Disease Detection for Resected Pancreatic Adenocarcinoma

Pancreatic Cancer Resectable

China
ResMed

Completed

Narval CC Mandibular Repositioning Device in the Second-line Treatment of Severe Obstructive Sleep Apnea Hypopnea (OSAH) (ORCADES)

Obstructive Sleep Apnea Syndrome

France
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Clinical Value of Breast High-Resolution MR Ductography in Patients With Pathological Nipple Discharge

Breast Neoplasms | Nipple Discharge

China
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Guangzhou First People's Hospital; Sun Yat-Sen... and other collaborators

Completed

MRD-directed Therapy for Low-risk and Intermediate-risk AML.

Acute Myeloid Leukemia | Minimal Residual Disease

China
Fondazione Italiana Linfomi - ETS

Active, not recruiting

Non-invasive Diagnostics and Monitoring of MRD and Clonal Evolution in Waldenström's Macroglobulinemia and in IgM-MGUS (FIL_BIOWM)

Waldenstrom Macroglobulinemia

Italy
First Affiliated Hospital Xi'an Jiaotong University
Second Affiliated Hospital of Xi'an Jiaotong University

Not yet recruiting

MRD Test in Common Risk Stage II Colorectal Cancer (HuaMC-1)

Stage II Colorectal Cancer

China
Stichting European Myeloma Network
Janssen Pharmaceutica

Recruiting

Phase 2 Study Applying MRD Techniques for Participants With Previously Untreated Multiple Myeloma Treated With D-VRd Prior To and After High-dose Therapy Followed by ASCT - TAURUS (TAURUS)

Multiple Myeloma

Austria, Greece, Italy, Netherlands, Germany
Exact Sciences Corporation
NSABP Foundation Inc

Not yet recruiting

EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

Breast Cancer
The First Affiliated Hospital of Zhengzhou University
BeiGene

Recruiting

MRD-guided Adjuvant Tislelizumab and Chemotherapy in Resected Stage IIA-IIIB NSCLC (Seagull)

NSCLC

China
FengYan Jin

Not yet recruiting

A Perspective, Single Center Study of the MRD-tailored Therapy in Patients With Newly Diagnosed Multiple Myeloma With Persistent Minimal Residual Disease After Initial Treatment (MRD)

Multiple Myeloma | Minimal Residual Disease
Nordic MDS Group

Unknown

Individual Molecular MRD Monitoring for MDS Patients After Allo-SCT

MDS | SCT | MRD

Denmark, Norway, Sweden
The Children's Hospital of Zhejiang University...

Completed

MRD Detection by NGS in Pediatric B-ALL

Acute Lymphoblastic Leukemia, Pediatric

China
Prof. Christina Peters
Amgen

Terminated

ALL SCTped 2012 FORUM Add-on Study Blina Post HSCT

Minimal Residual Disease | ALL, Childhood

Norway, Spain, Denmark, Austria, Belgium, Czechia, France, Italy, Poland, Slovakia
Gruppo Italiano Malattie EMatologiche dell'Adulto

Not yet recruiting

Kinetics and Impact on Survival of MRD in AML Patients Receiving Azacitidine and Venetoclax

Minimal Residual Disease | AML, Adult
Gruppo Italiano Malattie EMatologiche dell'Adulto

Completed

Risk-adapted, MRD-directed Therapy for Young Adults With Newly Diagnosed Acute Myeloid Leukemia (AML1310)

Acute Myeloid Leukemia

Italy
Sun Yat-sen University

Recruiting

Monitoring Minimal Residual Disease（MRD）in Pediatric B-acute Lymphoblastic Leukemia

B Acute Lymphoblastic Leukemia

China
Center for International Blood and Marrow Transplant...
National Marrow Donor Program

Recruiting

Molecular Evaluation of AML Patients After Stem Cell Transplant to Understand Relapse Events (MEASURE)

Acute Myeloid Leukemia in Remission

United States
Guangdong Provincial People's Hospital

Recruiting

MRD Monitoring in Lung Cancer After Resection

Lung Cancer

China
Guangdong Association of Clinical Trials

Recruiting

Adjuvant Treatment Based on MRD for EGFR Mutant NSCLC

MRD

China
Qilu Hospital of Shandong University
The Affiliated Hospital of Qingdao University; Shandong Provincial Hospital; Jinan... and other collaborators

Recruiting

Minimal Residual Disease-guided Adjuvant Therapy for Gastric Cancer

Stage II-III Gastric Cancer

China
Fondazione EMN Italy Onlus

Completed

Monitoring of Deep of Response During Lenalidomide Maintenance in MM Patients Achieving at Least Very Good Partial Response (MRD) (MRD)

Multiple Myeloma

Italy
Institut Paoli-Calmettes

Unknown

Tolerance and Efficacy of Subcutanous Low Doses Rituximab for CLL Consolidation Treatment (LLCRlowdoz)

Chronic Lymphocytic Leukemia

France
Stichting Hemato-Oncologie voor Volwassenen Nederland

Withdrawn

Study to Assess an Interphase Cycle With Flotetuzumab. (HOVON162AML)

AML

Netherlands
International Myeloma Foundation
Janssen Scientific Affairs, LLC; Celgene; Amgen; Trevie, Inc.

Active, not recruiting

Aggressive Smoldering Curative Approach Evaluating Novel Therapies and Transplant (ASCENT)

Smoldering Multiple Myeloma

United States
M.D. Anderson Cancer Center

Suspended

A PHASE IB STUDY OF IMMUNOTHERAPY WITH EX VIVO PRE-ACTIVATED AND EXPANDED CB-NK CELLS IN COMBINATION WITH CETUXIMAB, IN COLORECTAL CANCER PATIENTS WITH MINIMAL RESIDUAL DISEASE (MRD)

Colon Cancer | Resected Stage

United States
Guangdong Provincial People's Hospital
Haplox

Not yet recruiting

Efficacy Evaluation and Recurrence Monitoring of Therapy for Esophageal Squamous Cell Carcinoma Based on ctDNA-MRD.

Esophageal Squamous Cell Carcinoma | Minimal Residual Disease

China
Shanghai Tong Ren Hospital

Recruiting

Adaptive Treatment for Acute Myeloid Leukemia Based on D14 MRD Results (AVS)

AML | MRD

China
Sun Yat-sen University
Guangzhou Burning Rock Dx Co., Ltd.

Active, not recruiting

Predictive Value of Postoperative Circulating Tumor DNA Monitoring for Colorectal Cancer Recurrence

Colorectal Cancer

China
Yanhong Deng
GeneCast Biotechnology Co., Ltd.

Recruiting

Neoadjuvant Chemoradiotherapy Plus Sintilimab for Intermediate/High Immunoscore Locally Advanced Rectal Cancer (SILAR)

Rectal Cancer

China
University of Michigan Rogel Cancer Center
Janssen Scientific Affairs, LLC

Active, not recruiting

Phase 2 Study With Minimal Residual Disease (MRD) Driven Adaptive Strategy in Treatment for Newly Diagnosed Multiple Myeloma (MM) With Upfront Daratumumab-based Therapy

Multiple Myeloma

United States
The First Affiliated Hospital with Nanjing Medical...

Recruiting

ctDNA Detection of MRD in Predicting Postoperative Recurrence in Biliary Tract Cancers：A Multicenter Prospective Trial

Biliary Tract Cancer

China
National Research Center for Hematology, Russia
Federal Research Clinical Center of Federal Medical & Biological Agency,... and other collaborators

Recruiting

The Role of Allo-HSCT in MRD-negative Patients With AML Under the Age of 60 Years in the First Complete Remission

AML

Russian Federation
Therapeutic Advances in Childhood Leukemia Consortium
Genzyme, a Sanofi Company

Terminated

Clofarabine With Cytarabine for Patients With Minimal Residual Disease Positive Leukemia

Minimal Residual Disease | Leukemia, Lymphoblastic, Acute | Leukemia, Myelogenous, Acute

United States
Peking University People's Hospital

Recruiting

Assessment of Measurable Residual Disease in Allo-HSCT Using Digital Polymerase Chain Reaction

Acute Leukemia | MDS | CML | MDS/MPN

China
Sheng-Li Xue, MD
Northern Jiangsu Province People's Hospital; The Second People's Hospital of... and other collaborators

Recruiting

Inotuzumab Ozogamicin in the Treatment of MRD+ After HSCT of ALL

Hematopoietic Stem Cell Transplantation | ALL | MRD-positive

China
Memorial Sloan Kettering Cancer Center

Recruiting

Stopping Maintenance Therapy in People With Multiple Myeloma in MRD-Negative Remission

Plasma Cell Myeloma

United States

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