Search clinical trials for: MTHFR C677T Polymorphism

Total 1130 results

Ain Shams University

Completed

Prevalence of Thrombophilic Gene Polymorphism (MTHFR C677T) in COVID-19patients ((MTHFR)C677T)

COVID 19 Associated Coagulopathy

Egypt
Sun Yat-sen University

Completed

A Retrospective Cohort Study: Influence of MTHFR C677T and A1298C Polymorphisms on the Survival of Pediatric Patients With Non-Hodgkin's Lymphoma

Pediatric Non-Hodgkin Lymphoma

China
Universidad de Costa Rica
Universitat Autonoma de Barcelona

Unknown

C677T and A1298C MTHFR Polymorphisms and Fluoropyrimidine Effectiveness in Metastatic Colon Cancer

Colon Cancer | Chemotherapy Effect | Chemotherapeutic Toxicity | MTHFR Gene Mutation

Costa Rica
Federal University of Paraíba

Completed

Polymorphism C677T MTHFR and Folate Intake in Inflammatory Biomarkers

Overweight and Obesity
Federal University of Paraíba

Completed

Polymorphism C677T MTHFR and Effects of Folate Intake

Overweight and Obesity
Pamlab, Inc.
Massachusetts General Hospital

Completed

A Placebo-Controlled Study of Physiologic Effects of L-methylfolate in Schizophrenia Patients

Schizophrenia

United States
Shenzhen Ausa Pharmed Co.,Ltd
Peking University First Hospital; The First Affiliated Hospital of Shanxi Medical... and other collaborators

Not yet recruiting

China Stroke Primary Prevention Trial for Subjects With H-type Hypertension and MTHFR 677 CC/CT Genotype (CSPPT2-CC/CT)

Hypertension

China
Shenzhen Ausa Pharmed Co.,Ltd
Peking University First Hospital; The First Affiliated Hospital of Shanxi Medical... and other collaborators

Not yet recruiting

China Stroke Primary Prevention Trial for Subjects With Hypertension and MTHFR 677 TT Genotype (CSPPT2-TT) (CSPPT2-TT)

Hypertension

China
Assiut University

Not yet recruiting

The Role of Prothrombin Gene and Methylenetetrahydrofolate Reductase(MTHFR) Gene Polymorphisms as Risk Factors for Recurrent Miscarriage

Recurrent Miscarriage
S.LAB (SOLOWAYS)
Center of New Medical Technologies; Triangel Scientific

Completed

Evaluating the Impact of B Vitamin Supplementation (Soloways™) on Homocysteine and LDL-C Levels in Patients With MTHFR, MTR, and MTRR Polymorphisms. (VITAGEN-H)

Hyperlipoproteinemias | Hyperhomocysteinemia

Russian Federation
University of Ulster

Completed

Blood Pressure and Central Haemodynamics in Healthy Adults Stratified by MTHFR Genotype (RAFA Obs)

Blood Pressure

United Kingdom
University of Ulster

Completed

Blood Pressure Lowering Effect of B-vitamins in Adults With a Genetic Pre-disposition to Elevated Blood Pressure. (RAFA)

Blood Pressure

United Kingdom
Sun Yat-sen University

Completed

A Retrospective Cohort Study: The Influence of MTHFR C677T and A1298C on the High-dose Methotrexate-Related Toxicities in Pediatric Patients With Non-Hodgkin Lymphoma

Pediatric NHL

China
London School of Hygiene and Tropical Medicine
University of Ulster

Terminated

Pilot Evaluation of the Effect of Riboflavin Supplementation on Blood Pressure and Possible Effect Modification by the MTHFR C677T Genotype (RiboBP)

High Blood Pressure | MTHFR C677T Genotype

Gambia
Shenzhen Ausa Pharmed Co.,Ltd
Peking University First Hospital; Nanfang Hospital of Southern Medical University and other collaborators

Unknown

H-Type Hypertension Precision Medicine Trial

Hypertension

China
Universität des Saarlandes

Completed

Effect of Folic Acid on Primary Folate Forms in Relation to MTHFR

the Effect of MTHFR C677T on Folate Metabolism

Germany
Shenzhen Ausa Pharmed Co.,Ltd
Nanfang Hospital of Southern Medical University

Withdrawn

CSPPT- Chronic Kidney Diseases Study (CSPPT-CKD)

Hypertension | Hyperhomocysteinemia

China
Health Diagnostic Laboratory, Inc.

Completed

Prevalence of MTHFR Polymorphisms in Venous Disease (MTHFR)

Thrombosis | Varicose Veins | Venous Disease | MTHFR

United States
Moshe Flugelman

Terminated

Examining B12 Deficiency Associated With C677T Mutation on MTHFR Gene in Terms of Commonness and Endothelial Function

B12 Deficiency Combined With C677T Mutation on MTHFR Gene

Israel
Shenzhen Ausa Pharmed Co.,Ltd
Anhui Medical University

Completed

China Stroke Primary Prevention Trial (CSPPT)

Primary Hypertension

China
Pamlab, Inc.
InfoMedics, Inc.

Completed

Deplin® P.L.U.S. Program (Progress Through Learning Understanding & Support)

Major Depressive Disorder

United States
Shenzhen Ausa Pharmed Co.,Ltd
Peking University First Hospital; China Medical University, China; Fudan University and other collaborators

Unknown

Efficacy of Amlodipine-folic Acid Tablets on Reduction of Blood Pressure and Plasma Homocysteine

Essential Hypertension

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Predictive Determinants of Nephrotic Syndrome Remission in Patients With At-risk Polymorphism of APOL1 (NEPHROL1)

Focal Segmental Glomerulosclerosis | Nephrotic Syndrome | APOL1 Associated Kidney Disease

France
Yi Han
Qianfoshan Hospital

Recruiting

Prospective Observational Association Between SLCO1B1 Gene Polymorphism and the Anti-factor Xa Activity of Edoxaban in Patients With Moderate to Severe Renal Insufficiency

Renal Insufficiency | Gene Polymorphism | Edoxaban

China
Ospedale San Raffaele

Recruiting

Genetics in the Progression of Nephropathies

Hypertension | AKI | CKD | Hematologic Malignancy | Ckd-Mbd | ADPKD | Bone Marrow Transplant Complications | CKD (Chronic Kidney Disease) Stage 5D

Italy
The Affiliated Hospital Of Guizhou Medical University

Not yet recruiting

Population Pharmacokinetic Study of the Effect of Polymorphisms in the ABCB1 and CES1 Genes on the Pharmacokinetics of Dabigatran

Combined Analysis of Polymorphisms and Dabigatran Pharmacokinetic Parameters
Institute of Liver and Biliary Sciences, India

Recruiting

Prevalence of CYP3A5 Polymorphisms in the Donors and ABCB1 Polymorphisms in the Recipients Undergoing Pediatric Liver Transplant and Their Influence on Tacrolimus Levels and Graft Function.

Pediatric Liver Transplant

India
Helwan University

Not yet recruiting

Palbociclib in Metastatic Breast Cancer: Gene Polymorphism-based Study in Egyptian Patients. (Palbociclib)

Metastatic Breast Cancer | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Hormone-receptor-positive Breast Cancer
Mahidol University

Not yet recruiting

The Efficacy of Pedometer-motivated Physical Activity for the Management of Patients With MASLD.

BMI | Metabolic Syndrome | Insulin Resistance | NAFLD | Genetic Polymorphism | Cardiovascular Disease (CVD) | MASLD | Daily Step Count
Augusto Vaglio

Recruiting

GWAS and EWAS in Patients With Erdheim-Chester Disease

Erdheim-Chester Disease

France, Italy, Spain
Lebanese University
Haykel Hospital

Recruiting

Precision Therapy for Solid Tumors: Synergistic CDK4/6 Inhibition and Anti-VEGF Targeting LncRNA (PTST_PALBEVA)

Cancer | Breast Cancer | Colorectal Cancer | Ovarian Cancer | Lung Cancer | Chemotherapy | Solid Tumor | Immunotherapy | Targeted Therapy | Precision Therapy

Lebanon
University of Évora
Universidade Nova de Lisboa; Comprehensive Health Research Centre; Unidade Local... and other collaborators

Recruiting

Effects of Vitamin D on Health Promotion During Pregnancy and Its Impact on Prematurity-Related Outcome (VitDTracking)

Vitamin D Deficiency | Pregnancy

Portugal
University of Virginia
American Heart Association

Recruiting

Implementation of Onsite Rapid CYP2C19 Assay for Genotype Guided Dual Antiplatelet Therapy After Acute Ischemic Stroke (ORCA-AIS)

Ischemic Stroke | CYP2C19 Polymorphism

United States
Zunyi Medical College

Recruiting

CYP2C19 Genotype-Guided P2Y12 Receptor Inhibitor Selection After Complex Percutaneous Coronary Intervention

ACS - Acute Coronary Syndrome | CYP2C19 Polymorphism

China
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Effect of Mutations in T2DM Susceptibility Genes on the Expression of Susceptibility Genes in Patients With T2DM and Controls

Type 2 Diabetes Mellitus | Genetic Mutations | Gene Polymorphisms | Susceptibility, Genetic

China
S.LAB (SOLOWAYS)
Center of New Medical Technologies

Not yet recruiting

Trial to Evaluate the Efficacy of a Zinc, Selenium, and L-Tyrosine Supplement in the Prevention of Thyrotoxicosis in Subjects With r25191G/A SEPP1 Polymorphism (ZEST-PREP)

Thyrotoxicosis

Russian Federation
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Association of Gene Polymorphism With Susceptibility to T2DM and the Therapeutic Responses to Exenatide in Chinese Patients With T2DM

Type 2 Diabetes Mellitus | Susceptibility, Genetic

China
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Hyperlactacidemia in Major Abdominal Surgery and Monocarboxylate Receptors (NETTUNO)

Postoperative Complications | Surgical Procedure, Unspecified | Hyperlactatemia | Abdomen Disease

Italy
Novosibirsk Scientific Research Institute for Circulatory...

Recruiting

The Effect of Polymorphism of the GUCY1A3 rs7692387 Gene on Cardiovascular Events After Coronary Artery Bypass Grafting.

to Evaluate the Association of GUCY1A3 rs7692387 Gene Polymorphism Carrier on the Development of Cardiovascular Events After Coronary Artery Bypass Grafting

Russian Federation
Lithuanian University of Health Sciences

Recruiting

The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder

Inflammation | Cognitive Dysfunction | Genetic Predisposition to Disease | Endotoxemia | Major Depressive Disorder | Blood Brain Barrier Defect

Lithuania
October 6 University
University of Florida; Beni-Suef University; National Heart Institute, Egypt

Recruiting

Effect of Genetic Polymorphisms on the Clinical Response to SGLT2 Inhibitors in Heart Failure Patients

Heart Failure | Genetic Polymorphisms

United States
Instituto Bernabeu

Not yet recruiting

TRAP Study: Testosterone for Androgen Receptor Polymorphism (TRAP)

Fertility Disorders

Spain
Marmara University

Not yet recruiting

Single Gene Polymorphisms Associated With Molar-Incisor Hypomineralization

Molar-Incisor Hypomineralization
Assiut University

Not yet recruiting

Association Between ABO Polymorphism and Gastric/Colorectal Cancers

Gastric Cancer | Colo-rectal Cancer
The Republican Research and Practical Center for...
Belarusian State Medical University

Recruiting

To Develop an Algorithm for Predicting the Unfavorable Course of Sepsis in Children Based on a Comprehensive Assessment of Immunological, Biochemical and Molecular Genetic Markers

Sepsis

Belarus
LI YAN

Not yet recruiting

Study on the Association of GSTP1 and Other Gene Polymorphisms With Platinum-induced Myelosuppression

Non-small Cell Lung Cancer
Janssen Research & Development, LLC

Recruiting

Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib (COCOON)

Carcinoma, Non-Small-Cell Lung

United States, Taiwan, Korea, Republic of, Malaysia, Turkey, France, Spain, China, Germany, Argentina
Affiliated Hospital of Nantong University

Not yet recruiting

CYP1A2, ABCB1, CYP2C9 and Plasma Concentration of Agomelatine in Adult Patients With Depression

Depression | Polymerase Chain Reaction | Polymorphism, Genetic | CYP1A2 Polymorphism | Plasma Concentration | CYP2C9 Polymorphism
Technical University of Madrid

Recruiting

Erythrocyte Transport of Lactate During Exercise (TELE Project) (TELE)

Energy Metabolism

Spain
Lebanese University
Haykel Hospital

Recruiting

Exploring Cancer-Associated Thromboembolism Prognosis Biomarkers and Polymorphisms (CAT_PB)

Cardiovascular Diseases | Immune System Diseases | Cancer | Breast Cancer | Hepatocellular Carcinoma | Lung Cancer | Chemotherapy | Solid Tumor | Prostate Cancer | Thromboembolism | Colon Cancer | Immunotherapy | Inflammatory Diseases

Lebanon

Search clinical trials for: MTHFR C677T Polymorphism

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