Search clinical trials for: Major bleeding

Total 6583 results

Population Health Research Institute

Not yet recruiting

Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial (BRACKETS)

Chronic Kidney Diseases | Bleeding | Surgery | Acute Kidney Injury
Institut universitaire de cardiologie et de pneumologie...

Not yet recruiting

Recurrent or Persistent Device Related Thrombus After Left Atrial Appendage Occlusion: The RE-DRT Study (RE-DRT)

Thromboembolic Event | Percutaneous Left Atrial Appendage Occlusion (LAAO) | Device-related Thrombus (DRT) | Major Cardioembolic Events | Major Bleeding - TIMI Classification
AstraZeneca
Parexel

Recruiting

A Study to Describe the Characteristics, Health Care Interventions and Outcomes of Patients With Major Bleedings in the Presence of Factor Xa Inhibitor Treatment (REVERXaL)

Major Bleeding

United States, Japan, Germany
Sohag University

Not yet recruiting

"ORBIT" Versus "HAS-BLED" Scores in Predicting Major Bleeding in Patients With Atrial Fibrillation Receiving Oral Anticoagulants.

Patients With Atrial Fibrillation Receiving Oral Anticoagulants
AstraZeneca
LOGEX Healthcare Analytics Amsterdam The Netherlands

Recruiting

Retrospective Study on Characteristics and Outcomes in Hospitalised Patients Treated With Ondexxya

Hemorrhage

Netherlands
Laboratoire français de Fractionnement et de Biotechnologies

Recruiting

A Phase 3 Study of the Safety and Efficacy of Coagulation Factor VIIa (Recombinant) for the Prevention of Excessive Bleeding in Patients With Congenital Hemophilia A or B With Inhibitors to Factor VIII or IX Undergoing Elective Major Surgical Procedures SCOPE HIM (SCOPE HIM)

Hemophilia

United States, Thailand, Malaysia, Mexico, South Africa, Turkey
CSL Behring

Recruiting

Evaluation of BE1116 in Patients With Traumatic Injury and Acute Major Bleeding to Improve Survival ( TAP Study )

Traumatic Injury

United States, United Kingdom, Australia
Qilu Hospital of Shandong University
Shandong Provincial Hospital; Taian City Central Hospital

Recruiting

Safety of Anticoagulant Therapy After Tissue Glue for Gastric Varices

Anticoagulants and Bleeding Disorders | Tissue Adhesion | Gastric Varices Bleeding

China
Seoul National University Hospital

Not yet recruiting

Effect of Low Tidal Ventilation on Intraoperative Bleeding in Laparoscopic Major Hepatectomy

Liver Cirrhosis | Hepatocellular Carcinoma | Blood Loss, Surgical | Ventilator Lung

Korea, Republic of
Anthos Therapeutics, Inc.
Itreas

Recruiting

A Study Comparing Abelacimab to Apixaban in the Treatment of Cancer-associated VTE (ASTER)

Venous Thromboembolism | Pulmonary Embolism | Deep Venous Thrombosis

Austria, United States, Taiwan, Australia, Spain, Japan, Canada, Ireland, Italy, Korea, Republic of, France, Switzerland, Hungary, Netherlands, Latvia, Germany, Norway, Sweden, Czechia, United Kingdom
Anthos Therapeutics, Inc.
Itreas

Recruiting

A Study Comparing Abelacimab to Dalteparin in the Treatment of Gastrointestinal/Genitourinary Cancer and Associated VTE (MAGNOLIA)

Venous Thromboembolism | Pulmonary Embolism | Deep Venous Thrombosis

Austria, United States, Taiwan, Australia, Spain, Korea, Republic of, Italy, Hungary, France, Netherlands, Canada, Latvia, Germany, United Kingdom, Norway, Sweden, Ireland, Czechia, Switzerland
Octapharma

Recruiting

Study of OCTAPLEX in Patients With Acute Major Bleeding on DOAC Therapy With Factor Xa Inhibitor

Acute Major Bleeding

United States, Bosnia and Herzegovina, Croatia, Spain, Georgia, Italy, Poland, Germany, Austria, Turkey, United Kingdom, Ukraine, France
University of Manitoba
Canadian Institutes of Health Research (CIHR); Health Sciences Centre Foundation... and other collaborators

Recruiting

A Trial of a Hospital Policy of Tranexamic Acid Use to Reduce Transfusion in Major Non-cardiac Surgery (TRACTION)

Major Non-cardiac Surgeries

Canada
Hospital de Clinicas de Porto Alegre
University of Sao Paulo; Santa Casa de Porto Alegre

Recruiting

The Effects of Tranexamic Acid or Placebo on Perioperative Bleeding in Adults Undergoing Liver Transplantation.

Hemorrhage

Brazil
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

Bleeding Frequency Under Anticoagulant Treatment in Pulmonary Hypertension (HEMA-HTP)

Pulmonary Arterial Hypertension

France
Novo Nordisk A/S

Completed

Safety and Efficacy of Activated Recombinant Human Factor VII in Haemophilia Patients With Inhibitors During and After Major Surgery

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

United States
Rennes University Hospital

Completed

Major Bleeding Risk Associated With Antithrombotics (SACHA)

Major Haemorrhage

France
Yonsei University

Active, not recruiting

A Randomized Comparison of CLOpidogrel Monotherapy Versus Extended Dual-antiplatelet Therapy Beyond 12 Months After Implantation of Drug-eluting StEnts in High-risk Lesions or Patients; A-CLOSE Trial

Coronary Artery Disease | DES

Korea, Republic of
Cipherome, Inc.
DHR Health Institute for Research and Development

Completed

Evaluating Pharmacogenomic Variants for Cardiology Therapeutics (CARES2)

Myocardial Infarction | Ischemic Stroke | Thrombosis | Bleeding | Stent Thrombosis

United States
Insel Gruppe AG, University Hospital Bern

Completed

Early Versus Late Initiation of Direct Oral Anticoagulants in Post-ischaemic Stroke Patients With Atrial fibrillatioN (ELAN): an International, Multicentre, Randomised-controlled, Two-arm, Assessor-blinded Trial (ELAN)

Ischaemic Stroke

Belgium, Ireland, Israel, Germany, India, United Kingdom, Austria, Switzerland, Finland, Norway, Italy, Portugal, Slovakia, Japan, Greece
Pfizer

Completed

Effectiveness And Safety Of Oral Anticoagulants Among Obese Patients With Non-Valvular A-Fib In VA Patients With Medicare

Obesity | Atrial Fibrillation | Anticoagulants

United States
Pfizer

Withdrawn

NOAC Portuguese Real World Study

Stroke | Systemic Embolism | Major Bleeding
Cardioangiologisches Centrum Bethanien

Completed

Effectivity and Safety of Different Anticoagulants in Patients With Thromboembolic Antiphospholipid Syndrome

Venous Thromboembolism | Antiphospholipid Syndrome | Major Bleed | Arterial Thromboembolism

Germany
Fujita Health University

Completed

Rivaroxaban Estimation With Warfarin in Atrial Fibrillation Patients With Coronary Stent Implantation Study (REWRAPS) (REWRAPS)

Coronary Artery Disease | Stroke | Atrial Fibrillation | All Cause Mortality | Fetal Blood Loss | Major Bleeding

Japan
Major Extremity Trauma Research Consortium

Enrolling by invitation

A Prospective Study of Early Mechanical Stabilization and Bleeding in Disruption of the Pelvic Ring (EMS-BIND)

Pelvic Fracture

United States
University of Padova

Completed

Edoxaban and Frailty in Senior Individuals (ESCAPE)

Atrial Fibrillation

Italy
Liverpool University Hospitals NHS Foundation Trust
Liverpool Heart and Chest Hospital NHS Foundation Trust; Countess of Chester... and other collaborators

Completed

The Risk of Major Bleeding With Novel Anti-platelets: A Comparison of Ticagrelor With Clopidogrel in a Real World Population of 5000 Patients Treated for Acute Coronary Syndrome (ROBOT-ACS)

Bleeding | Acute Coronary Syndrome | Ticagrelor | Clopidogrel | Novel Anti-platelets

United Kingdom
Bristol-Myers Squibb

Completed

A Study to Compare the Risk of a Major Bleeding in Participants Who Received Blood Thinning Medications Following a Blood Clot

Venous Thromboembolism (VTE)

United States
Alexion Pharmaceuticals
Population Health Research Institute; Portola Pharmaceuticals, LLC (a wholly...

Completed

A Study in Participants With Acute Major Bleeding to Evaluate the Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of Direct and Indirect Oral Anticoagulants (Extension Study)

Bleeding

United States, Belgium, Canada, France, Germany, Japan, Netherlands, Spain, United Kingdom
CSL Behring
Kaiser Permanente

Completed

An Observational Cohort Study to Investigate the Risk of Thromboembolic Events in Patients Receiving Kcentra® or Plasma to Reverse Vitamin K Antagonist (VKA) Therapy in the Setting of Acute Major Bleeding

Hemorrhage

United States
University Hospital, Strasbourg, France

Terminated

Tranexamic Acid Versus Placebo to Reduce Perioperative Bleeding After Major Hepatectomy

Blood Loss, Surgical

France
China Medical University Hospital
Ministry of Health and Welfare, Taiwan; An-Nan Hospital, China Medical University

Completed

The Major Bleeding Risk Following Hepatectomy

Surgery--Complications | Postoperative Hemorrhage | Gastrointestinal Hemorrhage

Taiwan
Bayer
Janssen Research & Development, LLC

Terminated

A Nationwide Observational Study Looking at Effectiveness and Bleeding Complications of NOACs vs. VKA in Non-valvular Atrial Fibrillation Patients. (PROTECT-AF)

Non-valvular Atrial Fibrillation

Norway
Samsung Medical Center

Completed

Safety and Efficacy of Edoxaban in Thoracoscopic Ablation

Atrial Fibrillation | Anticoagulants and Bleeding Disorders

Korea, Republic of
Haukeland University Hospital
University College of Southeast Norway

Completed

Mild Hypothermia Influence on Patient Outcome in Major Abdominal Surgery

Bleeding | Surgical Site Infection

Norway
Scientific Institute San Raffaele

Unknown

Triple or Dual Antithrombotic Therapy After PCI (TRIDUAL-PCI) Coronary Intervention in Patients With Non-valvular Atrial Fibrillation. Real-world Italian Multicenter Registry (TRIDUAL-PCI) (TRIDUAL-PCI)

Myocardial Infarction | Coronary Disease | Atrial Fibrillation | Anticoagulant-induced Bleeding

Italy
Acibadem University
Pamukkale University; Cukurova University; Gazi University; Baskent University; Ege... and other collaborators

Completed

Major Pelvic Hemorrhage in Complex Surgery

Pelvic Bleeding

Turkey
Denver Health and Hospital Authority
University of Colorado, Denver; U.S. Army Medical Research and Development...

Terminated

Control of Major Bleeding After Trauma Study (COMBAT)

Trauma | Hemorrhagic Shock

United States
Xiaofan Wu

Unknown

Efficacy and Safety of Low Dose Ticagrelor in Patients With Unstable Angina Pectoris After Coronary Stent Implantation

Unstable Angina Pectoris | Coronary Stent Implantation

China
Bayer
Janssen Research & Development, LLC

Completed

Characterizing Recurrent Thromboembolism, Major Bleeding and All-Cause Death in Patients With Cancer-Associated Thromboembolism Treated With Rivaroxaban

Venous Thromboembolism

United States
Centre de Recherche de l'Institut Universitaire...

Completed

Aspirin Versus Aspirin+Clopidogrel as Antithrombotic Treatment Following TAVI (ARTE)

Myocardial Infarction | Stroke | Bleeding | Aortic Valve Disease

Canada, Chile, Spain
CUF Santarém Hospital

Unknown

Tranexamic Acid in Major Orthopedic Surgery: Comparison of 3 Dosage Regimen

Knee Osteoarthritis | Bleeding | Ankle Osteoarthritis | Tranexamic Acid
University of Alberta
Vancouver Coastal Health Research Institute

Completed

The Effect of Medication Timing on Anticoagulation Stability in Users of Warfarin: The "INRange" RCT

Atrial Fibrillation | Thromboembolism | Deep Venous Thrombosis | DVT | Thrombus Due to Heart Valve Prosthesis

Canada
Icahn School of Medicine at Mount Sinai

Completed

Aspirin Resistance and Percutaneous Coronary Intervention (PCI) (RESIST)

Stable Angina

United States
Biotronik, Inc.

Terminated

Combined Use of BIOTRONIK Home Monitoring and Predefined Anticoagulation to Reduce Stroke Risk (IMPACT)

Stroke | Atrial Fibrillation | Atrial Flutter | Major Bleeding | Embolism, Systemic Arterial

United States, Canada, United Kingdom, Denmark, Germany, Australia
Fondazione Policlinico Universitario Agostino Gemelli...
San Camillo Hospital, Rome

Completed

Trauma Associated Bleeding: Effectiveness of an Early Coagulation Support Protocol

Major Trauma
Seoul National University Hospital

Completed

The Impact of Early Surgery and Maintenance of Antiplatelet Therapy on Intraoperative Bleeding and Major Adverse Cardiovascular Event After Percutaneous Coronary Intervention

Acute Coronary Syndrome | Aspirin | Drug-eluting Stent

Korea, Republic of
Baim Institute for Clinical Research
Bristol-Myers Squibb; Eli Lilly and Company; Daiichi Sankyo, Inc.; Boston Scientific... and other collaborators

Completed

The Dual Antiplatelet Therapy Study (DAPT Study)

Coronary Artery Disease

United States, Australia, Czechia, New Zealand, United Kingdom, Germany, Hungary, Poland, France, Romania
Centre de Recherche de l'Institut Universitaire...
Edwards Lifesciences

Completed

Aspirin Versus Aspirin + ClopidogRel Following Transcatheter Aortic Valve Implantation: the ARTE Trial (ARTE)

Myocardial Infarction | Stroke | Aortic Valve Disease

Canada
University Hospital, Brest

Completed

Extended Duration of Oral Anticoagulant Therapy After a First Episode of Idiopathic Pulmonary Embolism: a Randomized Controlled Trial. "PADIS-PE" Study. (PADIS EP)

Pulmonary Embolism

France

Search clinical trials for: Major bleeding

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