Search clinical trials for: Microdose study

Total 118391 results

Pure Biologics S.A.
Presage Biosciences

Not yet recruiting

A Study of the Intratumoral Microdose Administration of PBA-0405 in Patients With Solid Tumors

Triple Negative Breast Cancer | Head and Neck Squamous Cell Carcinoma | Soft Tissue Sarcoma Adult
Shanglei Liu

Recruiting

Microdosing ICG for Serial Colonic Perfusion Study During Surgery

Perfusion; Complications

United States
TransCode Therapeutics

Recruiting

A Microdose Study of TTX-MC138-NODAGA-Cu64 in Subjects With Advanced Solid Tumors

Advanced Solid Tumor

United States
Peking University Third Hospital

Recruiting

A Clinical Study to Evaluate the Pharmacokinetics of Microdose Midazolam, Dabigatran, Pitavastatin, Atorvastatin and Rosuvastatin in Healthy Volunteers and Renal Impairment Patients

Chronic Kidney Disease

China
NWTraumatherapies
World Health Organization

Not yet recruiting

Northwest Therapies Trauma Psilocybin Study Compassionate Use Study (NWTTPS)

Trauma, Nervous System

United States
Xuanwu Hospital, Beijing

Completed

Safety and Efficacy of Low-dose hEparinization in Cerebral Angiography sTudy (SELECT)

Cerebral Angiography | Heparinization

China
Biogen

Completed

A Study to Evaluate Safety, Tolerability, and Distribution of a Microdose of Radiolabeled BIIB067 (99mTc-MAG3-BIIB067) Co-administered With BIIB067 (Tofersen) to Healthy Adults

Healthy Volunteers

United States
Dartmouth-Hitchcock Medical Center
Dartmouth College

Completed

A Microdose Evaluation Study of ABY-029 in Head and Neck Oncology Surgery

Head and Neck Cancer

United States
University of California, Davis

Active, not recruiting

A Study of Positive Emotions With Long COVID-19

Post-Acute COVID-19 Syndrome

United States
AlzeCure Pharma

Completed

Study Evaluating the Pharmacokinetics of a Single Microdose of ACD856

Alzheimer Disease | Cognition Disorder

Sweden
Noorik Biopharmaceuticals AG

Terminated

A Study of Micro Dose Ambrisentan in Hospitalized Patients With Respiratory Insufficiency Due to COVID-19

Covid19 | Hypoxemia

Spain, Croatia
Kadmon Corporation, LLC
Quotient Sciences

Completed

Human Absorption, Distribution and Metabolism Study (hAME) [14C]-KD025 (KD025-108)

Fibrosis | Autoimmune Diseases

United Kingdom
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Enpatoran Human Mass Balance and Absolute Bioavailability Study

Healthy

Netherlands
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Human Mass Balance Study of Pyronaridine

Malaria

Switzerland
National Council of Scientific and Technical Research...

Completed

Naturalistic Study of Microdosing With Psilocybin (NATMICRO)

Sleep | Cognitive Change | Mood Change | Creativity

Argentina
Praxis Bioresearch, LLC

Completed

Microdose Pharmacokinetic Study of PRX-P4-003 In Healthy Volunteers

Healthy Volunteers

United States
Dartmouth-Hitchcock Medical Center
Dartmouth College

Completed

A Microdose Evaluation Study of ABY-029 in Primary Sarcoma

Primary Soft-tissue Sarcoma

United States
Dartmouth-Hitchcock Medical Center
Dartmouth College

Completed

A Microdose Evaluation Study of ABY-029 in Recurrent Glioma (ABY-029)

Glioma

United States
University of Edinburgh
Medical Research Council

Completed

Exploratory Clinical Study of Neutrophil Activation Probe (NAP) for Optical Molecular Imaging in Human Lungs (NAP)

Acute Lung Injury

United Kingdom
Agios Pharmaceuticals, Inc.

Completed

A Safety and Pharmacokinetic Study of AG-881 in Healthy Male Participants Following Administration of a Single Oral Dose of [14C] AG-881 and Concomitant Intravenous Microdose of [13C315N3] AG-881

Healthy Male Participants

United States
Seoul National University Hospital

Completed

A Study Using Whole-body PET After Oral Microdose of 18F-labeled Liporaxel in Patients With Solid Tumor

Solid Tumor

Korea, Republic of
Pfizer

Completed

Single Dose Study With Unlabeled Dose and 14C-labeled Microdose of PF-06700841 in Healthy Male Subjects

Healthy Male Subjects

Netherlands
Agios Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Absorption, Distribution, Metabolism, Excretion and Absolute Bioavailability of AG-348 in Healthy Male Participants Following Administration of a Single Oral Dose of [14C]AG-348 and Concomitant Single Intravenous Microdose of [13C6]AG-348

Healthy Volunteers

United States
GlaxoSmithKline
Hammersmith Medicines Research

Completed

A Microdose Study in Healthy Subjects to Describe Intravenous Pharmacokinetics of GSK3191607

Malaria, Falciparum

United Kingdom
Cellphire Therapeutics, Inc.
Department of Health and Human Services

Completed

Evaluation of the Safety and Immunogenicity of Autologous Thrombosomes® in Healthy Human Subjects; A Microdose Escalation Study (Cohorts 1 - 4) and Repeat Microdose Immunogenicity Study (Cohort 5)

Healthy

United States
GlaxoSmithKline

Completed

Intravenous Microdose Pharmacokinetic (PK) Study With [14C]-GSK2239633

Asthma

Netherlands
GlaxoSmithKline

Completed

Phase 0 Microdose Study

Autoimmune Diseases

United States
Sirtris, a GSK Company
GlaxoSmithKline

Completed

A Clinical Study to Evaluate the Pharmacokinetics and the Absolute Bioavailability of SRT2104 Given as a 250mg Oral Suspension and Intravenous Microdose of 100 µg Carbon-14 Radio-labeled SRT2104 in Healthy Male Subjects

Diabetes Mellitus, Type 2

United Kingdom
Henrik Gregersen

Unknown

Microdose Study of Melphalan, Bortezomib and Dexamethasone (Phase-0-MM)

Multiple Myeloma

Denmark
Kasr El Aini Hospital

Completed

Comparative Study Between Minidose Long Protocol and Microdose Flare Protocol in Controlled Ovarian Hyperstimulation

Infertility
Seoul National University Hospital

Completed

Absolute Bioavailability of YH4808 With Accelerator Mass Spectrometry(AMS)-Based Microdose Study

Gastroesophageal Reflux Disease

Korea, Republic of
Janssen R&D Ireland

Completed

A Study to Assess the Absolute Bioavailability and Pharmacokinetics of Simeprevir (TMC435) Administered as Single Oral Doses of TMC435 and an Intravenous Microdose of [3H]-TMC435 in Healthy Male Patients

Healthy Male Participants

Belgium
TNO
Alloksys Life Sciences B.V.

Completed

Microdose and First-In-Human (FIH) Study of Recombinant Human Placental Alkaline Phosphatase (hRESCAP)

Healthy

Netherlands
Clavis Pharma

Completed

Elacytarabine Mass Balance Study in Healthy Volunteers

Not Applicable as This is a Mass Balance/Pharmacokinetic Study Performed in Healthy Subjects

United Kingdom
Weill Medical College of Cornell University

Withdrawn

Oral Microdose Lupron Versus Luteal Estradiol Trial in Poor Responder In Vitro Fertilization (IVF) Patients (OMLET)

Infertility

United States
Protalix

Completed

An Exploratory Phase 1 Microdose Study of PRX-105

Organophosphate Exposure

Israel
MicroDose Defense Products L.L.C.
University of Pittsburgh; U.S. Army Space and Missile Defense Command

Completed

A Study of Inhaled Atropine Sulfate in Healthy Adults

Organophosphorus Poisoning

United States
University of Edinburgh

Not yet recruiting

HPV Equity Study: Exploring Cervical Cancer Control in Scotland for Women With Experience of Priority Risks (HPV Equity)

Human Papilloma Virus
Icahn School of Medicine at Mount Sinai
Pfizer

Recruiting

Assessment of Supportive Care and Educational Needs to Guide Quality Care Improvements for Patients With Locally Advanced and Metastatic Bladder Cancer (ACCESS)

Focus Group | Screening Tool

United States
Bayer

Not yet recruiting

A Study to Learn About How Much Emodepside Gets Absorbed in the Blood and How Food Affects Its Absorption When Given as a New Type of Tablet to Healthy Participants

Soil-transmitted Helminth Infection | Onchocerciasis (River Blindness)
University of Liverpool
University of Bristol; Liverpool John Moores University; Economic and Social...

Not yet recruiting

Out-of-home Consumer Food Purchase Behaviour in the Presence and Absence of Value Pricing and Price Promotions

Food Selection | Eating Behavior | Healthy Eating

United Kingdom
University of Florence
Azienda Ospedaliera Città della Salute e della Scienza di Torino; University... and other collaborators

Recruiting

Italian Real-life obServational Study on the effecTiveness, sAfety and Tolerability of Atogepant in Migraine Patients (STAR)

Migraine | Chronic Migraine | Migraine Without Aura | Migraine With Aura

Italy
Jonathan Bath
University of Missouri-Columbia

Not yet recruiting

Laser In Situ Fenestration Study (LIFE)

Aortic Aneurysm | Endovascular Aneurysm Repair
Spinogenix
Avance Clinical Pty Ltd.

Not yet recruiting

Phase 2a Study of SPG601 in Adult Men With Fragile X Syndrome

Fragile X Syndrome

United States
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co...

Not yet recruiting

A Study of FDA022-BB05 in Advanced/Metastatic Solid Tumors

Advanced Solid Tumor

China
Unilever R&D
Atlantia Food Clinical Trials

Not yet recruiting

A Randomised, Double-blind, Placebo-controlled, Crossover Study to Evaluate the Effects of a Food Ingredient on Self-reported Stress in Healthy Adults

Stress

Ireland
Tan Tock Seng Hospital

Not yet recruiting

An Exploratory Study of a Wearable Robotic Hand Orthosis

Stroke

Singapore
Pfizer

Not yet recruiting

A STUDY TO LEARN HOW THE STUDY MEDICINE CALLED PF-07293893 AFFECTS MUSCLE BIOMARKERS OF HEALTHY ADULTS

Healthy Participants
University of Oxford

Not yet recruiting

7T Amygdala and Citalopram Study (7TAC)

Depressive Disorder | Depression | Mood Disorders | Cognition | Emotional Processing
Toronto Metropolitan University
McMaster University; University of Guelph; University of Waterloo; Health Canada; Public Health Agency of Canada (PHAC) and other collaborators

Recruiting

Canadian Beach Cohort Study

Gastrointestinal Diseases | Water-Related Diseases

Canada

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