Search clinical trials for: Microglial cells Activation

Total 13047 results

Weibing Miao, PhD

Recruiting

Microglial Cells Activation Imaging Using PET-CT With 18F-DPA714

Microglial Cells Activation Imaging

China
Assistance Publique - Hôpitaux de Paris
Roche Pharma AG; Institut du Cerveau et de la Moelle épinière

Recruiting

Effect of Ocrelizumab on Brain Innate Immune Microglial Cells Activation in MS Using PET-MRI With 18F-DPA714 (INN-MS)

Multiple Sclerosis | Relapse | Primary Progressive Multiple Sclerosis

France
University Hospital, Toulouse

Not yet recruiting

Study of Cellular Heterogeneity in Patients With Mastocytosis (MastCellHet)

Mastocytosis

France
University Hospital, Antwerp
Universiteit Antwerpen; AZ Jan Palfijn Gent

Not yet recruiting

Diagnosing Drug Allergy: the T is the Key (TAT)

Amoxicillin Allergy
Senti Biosciences

Recruiting

SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults With CD33 and/or FLT3 Blood Cancers Including AML/MDS

AML/MDS | CD33 Expressing Hematological Malignancies | FLT3 Expressing Hematological Malignancies

United States, Australia
University of Wisconsin, Madison
National Institute on Aging (NIA)

Recruiting

Comparison of Microglial Activation in Severe Asthma and Healthy Controls (MAIA-SC)

Asthma

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

REGulatory T Cells in Autism Induced by Maternal Immune Activation (REGAIN)

Autism Spectrum Disorder

France
Hospices Civils de Lyon

Recruiting

Characterisation of TLR4+ Blood Cells in Patients With Solid Cancer (ODYSSEE)

All Types of Solid Cancer

France
National Cancer Institute (NCI)

Recruiting

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder for Bladder Cancer Treatment, MODERN Study

Stage III Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage IV Bladder Urothelial Carcinoma AJCC v7 | Stage II Bladder Urothelial Carcinoma AJCC v6 and v7 | Muscle Invasive Bladder Urothelial Carcinoma

United States
Centre Hospitalier St Anne
Roche Pharma AG

Recruiting

Impact of Microglial Activation on Synaptic Density in Alzheimer's Disease (GliSyn)

Alzheimer Disease

France
Centre Hospitalier Universitaire de Nice

Recruiting

Predictive Value of Th1, Th2 and Th17 Cytokines on the Success of Embryo Implantation (ImmuNoFertilité)

Assisted Reproduction

France
Fundació Institut Germans Trias i Pujol
Germans Trias i Pujol Hospital; University of Turin, Italy; Instituto de Salud... and other collaborators

Recruiting

Safety and Impact of Dasatinib on Viral Persistence and Inflammation in People With HIV Under Antiretroviral Treatment

HIV Infection Primary

Spain
Johns Hopkins University
United States Department of Defense

Not yet recruiting

Study of [11C]CPPC as a Clinical PET Radioligand Biomarker of Microglial Activation in ALS

ALS
Prof. Dr. Thomas Luft

Recruiting

The Endothelial Cell Dysfunction and Outcome Project for Hematological Neoplasms (EndoCDO-H)

Endothelial Dysfunction | Hematological Neoplasm

Germany
Ludwig-Maximilians - University of Munich

Recruiting

Clearance Mechanisms in Atypical Neurodegenerative Diseases (PeptiClear)

Neurodegenerative Diseases | Frontotemporal Degeneration

Germany
Assistance Publique - Hôpitaux de Paris
Institut Imagine

Not yet recruiting

Are Mast Cells Involved in Autoinflammatory Diseases (INFLAMAST)

Autoinflammatory Disease | FMF | TRAPS | MKD | Cryopyrin Associated Periodic Syndrome | Haploinsufficiency

France
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of Relatlimab Plus Nivolumab in Pediatric and Young Adults With Hodgkin and Non-Hodgkin Lymphoma (RELATIVITY-069)

Lymphoma, Non-Hodgkin | Hodgkin Disease

United States, France, Netherlands, Australia, United Kingdom, Italy, Spain, Germany
Zhongnan Hospital

Recruiting

Clinical Study of MAK Immune Cells in the Treatment of PHC

Primary Hepatocellular Carcinoma

China
Nurix Therapeutics, Inc.

Recruiting

A Study of NX-1607 in Adults With Advanced Malignancies

Cervical Cancer | Gastric Cancer | Head and Neck Squamous Cell Carcinoma | Non-small Cell Lung Cancer (NSCLC) | Metastatic Urothelial Carcinoma | Ovarian Cancer, Epithelial | Metastatic Castration-resistant Prostate Cancer (mCRPC) | Triple Negative Breast Cancer (TNBC) | Malignant Pleural Mesothelioma... and other conditions

United States, United Kingdom
Assistance Publique - Hôpitaux de Paris
National Research Agency, France

Recruiting

Characterization of the microVAScular Dysfunction in Covid-19 ARDS (VASCOV)

ARDS, Human | COVID-19 Acute Respiratory Distress Syndrome

France
ImmunoVaccine Technologies, Inc. (IMV Inc.)
Merck Sharp & Dohme LLC

Recruiting

DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (VITALIZE)

Relapsed Diffuse Large B-cell Lymphoma | Refractory Diffuse Large B-cell Lymphoma

Australia, Spain, United States, France, Hungary, New Zealand, Poland, Serbia, Canada, Romania
Columbia University
National Institute on Aging (NIA)

Recruiting

Discovery and Validation of Genetic Variants Affecting Microglial Activation in Alzheimer's Disease

Alzheimer Disease

United States
CellSight Technologies, Inc.
University of California, San Francisco

Recruiting

Imaging Immune Activation in COVID-19

Covid19 | SARS-CoV Infection

United States
CellSight Technologies, Inc.

Recruiting

Imaging of T-cell Activation With [18F]F-AraG in Advanced Non Small Cell Lung Cancer

Non Small Cell Lung Cancer

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Impact of a Monoamine Oxidase Inhibitor on the Phenotype of Blood Mononucleated Cells in Patients With COVID-19 (MAOi-COV19)

SARS-CoV2 Infection

France
James M Noble, MD, MS, CPH, FAAN
National Institute on Aging (NIA)

Recruiting

Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease (ADVISe)

Alzheimer Disease

United States
Brigham and Women's Hospital
U.S. Army Medical Research Acquisition Activity

Recruiting

Role of Microglial Activation and Norepinephrine Transporter Abnormalities in Pathogenesis of MS-related Fatigue

Multiple Sclerosis

United States
Brigham and Women's Hospital
Genzyme, a Sanofi Company

Not yet recruiting

Effect of Alemtuzumab on Microglial Activation Positron Emission Tomography (PET) in Multiple Sclerosis

Multiple Sclerosis

United States
Centre for Addiction and Mental Health
The Physicians' Services Incorporated Foundation

Recruiting

Minocycline as Adjunctive Treatment for Treatment Resistant Depression (MINDEP2)

Treatment Resistant Depression

Canada
The University of Texas Health Science Center,...

Recruiting

Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: A Dimensional Approach

Neuropsychiatric Syndromes

United States
CellSight Technologies, Inc.
National Institute of Allergy and Infectious Diseases (NIAID); University of...

Recruiting

Imaging Immune Activation in HIV by PET-MR

HIV Infections

United States
Erasmus Medical Center

Recruiting

Determination of Peripheral Immune Cell Activity During Treatment With Either Surgery or Radiotherapy in Patients With Early Stage NSCLC (HAMLET)

Non-small Cell Lung Cancer

Netherlands
Centre Leon Berard
National Cancer Institute, France

Recruiting

Adapting Treatment to the Tumor Molecular Alterations for Patients With Advanced Solid Tumors: MyOwnSpecificTreatment (MOST plus)

Malignant Solid Neoplasms

France
National Cancer Institute (NCI)

Active, not recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Glioma | Hematopoietic and Lymphoid Cell Neoplasm | Melanoma | Lymphoma | Multiple Myeloma | Recurrent Ovarian Carcinoma | Breast Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Lung Carcinoma | Recurrent Skin Carcinoma | Gastric Carcinoma | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory... and other conditions

United States, Puerto Rico, Guam
University Hospital, Montpellier
Centre Hospitalier Universitaire de Nīmes

Completed

Microglial Activation in Narcolepsy Type 1 and Kleine-Levin Syndrome: Positron Emission Tomography (PET) Study in [18F] DPA-714 (NARCOGLIE)

Kleine-Levin Syndrome | Narcolepsy 1

France
NantCell, Inc.
National Cancer Institute (NCI)

Completed

QUILT-3.011 Phase 2 Yeast-Brachyury Vaccine Chordoma

Chordoma

United States
Turku University Hospital

Enrolling by invitation

Does Microglial Activation Promote Lesion Growth and Progression Among Multiple Sclerosis Patients (FUP-MS)

Multiple Sclerosis

Finland
Turku University Hospital

Active, not recruiting

Effect of Teriflunomide Treatment on Microglial Activation in an MS Patient Cohort at Risk of Progression (TERIPET)

Multiple Sclerosis

Finland
Turku University Hospital

Active, not recruiting

Effect of Cladribine Treatment on Microglial Activation in the CNS (CLADPET)

Multiple Sclerosis

Finland
Centre for Addiction and Mental Health
McMaster University

Active, not recruiting

Microglial Activation in Inflammatory Bowel Disease

Inflammatory Bowel Diseases | Major Depressive Episode

Canada
Ludwig-Maximilians - University of Munich

Active, not recruiting

Activity of Cerebral Networks, Amyloid and Microglia in Aging and Alzheimer's Disease (ActiGliA)

Alzheimer Disease | Corticobasal Syndrome
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

Obesity | Psoriasis | Dyslipidemia | Atherosclerotic Cardiovascular Disease | Cardiometabolic Diseases

United States
BioXcel Therapeutics Inc
Cognitive Research Corporation

Completed

Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal (RELEASE)

Opioid Withdrawal

United States
University of Nebraska
Sanofi; National Institute of Neurological Disorders and Stroke (NINDS); Nebraska...

Completed

Leukine (Sargramostim) for Parkinson's Disease

Parkinson's Disease

United States
University Hospital, Toulouse
Institut National de la Santé Et de la Recherche Médicale, France

Completed

Neurotropism and Neuroinflammation in COVID-19 Patients With Delirium. (BRAINSTORM)

Delirium | Covid19 | Post-traumatic Stress Disorder

France
Bryan Cotton
Queen Mary University of London; NHS Blood and Transplant

Completed

Early Use of Cryoprecipitate With Major Hemorrhage Protocol (MHP) Activation

Trauma Injury

United Kingdom, United States
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

PET Imaging to Delineate Macrophage Activation in Diabetic Gastroparesis

Diabetes | Gastroparesis With Diabetes Mellitus

United States
Bristol-Myers Squibb

Completed

A Study to Evaluate the Safety, Tolerability, and Efficacy of Relatlimab in Relapsed or Refractory B-Cell Malignancies

Hematologic Neoplasms

United States, Canada
University of Erlangen-Nürnberg Medical School

Completed

Immunophenotyping From Blood of Patients With Malignant Gliomas

Glioblastoma Multiforme | Anaplastic Astrocytoma

Germany
Brigham and Women's Hospital
Biohaven Pharmaceuticals, Inc.

Completed

Effect of Verdiperstat on Microglial Activation in Well-characterized MSA Patients

Multiple System Atrophy | Multiple System Atrophy, Parkinson Variant (Disorder) | Multiple System Atrophy, Cerebellar Variant | Multiple System Atrophy (MSA) With Orthostatic Hypotension

United States

Search clinical trials for: Microglial cells Activation

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