Search clinical trials for: Monoclonal

Total 4006 results

Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Bone Marrow Transplantation in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Small Intestine Cancer | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous/Nonmalignant Condition

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Therapy, Cyclophosphamide, and Total-Body Irradiation Followed by Peripheral Stem Cell Transplantation in Treating Patients With Advanced Recurrent Acute Lymphocytic Leukemia

Leukemia

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation

Cancer

United States
Fred Hutchinson Cancer Center

Completed

Monoclonal Antibody Followed by Bone Marrow Transplantation in Treating Patients With Acute Myelogenous Leukemia in Remission or First Relapse

Leukemia
ImmunoGen, Inc.

Completed

Maytansinoid DM4-Conjugated Humanized Monoclonal Antibody huC242 in Treating Patients With Solid Tumors

Pancreatic Cancer | Non-colorectal Cancer

United States
University of Arizona
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Therapy in Treating Patients With Advanced Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous/Nonmalignant Condition

United States
Amgen

Completed

A Multiple Dose Study to Evaluate Subcutaneous AMG 108 in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis
Tracon Pharmaceuticals Inc.

Completed

Phase 1, Open-label, Dose Escalation Study of TRC093, in Patients With Locally Advanced or Metastatic Solid Tumors

Cancer | Neoplasm Metastasis

United States
University of Medicine and Dentistry of New Jersey
National Cancer Institute (NCI)

Terminated

12-O-Tetradecanoylphorbol-13-acetate in Treating Patients With Hematologic Cancer or Bone Marrow Disorder

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Precancerous/Nonmalignant Condition

United States
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study of Omeprazole Magnesium 20 mg DR Capsules Under Fasting Conditions

Healthy

India
Abbott

Completed

Human Anti-TNF Monoclonal Antibody Adalimumab in Canadian Subjects With Moderate to Severe Crohn's Disease (ACCESS) (ACCESS)

Crohn's Disease

United States
Pfizer

Completed

A Phase II Study Looking at Moderate to Severe Osteoarthritis Knee Pain

Osteoarthritis

United States
Weill Medical College of Cornell University

Completed

Monoclonal Antibody Therapy in Treating Patients With Prostate Cancer That Has Not Responded to Hormone Therapy

Prostate Cancer

United States
Amgen

Completed

Phase 2 Study of ABX-EGF (Panitumumab) in Japanese Subjects With M-colorectal Cancer

Metastatic Colorectal Cancer
Novartis

Terminated

Efficacy and Safety of Subcutaneous Versus Intravenous ACZ885 in Adult Patients With Established Rheumatoid Arthritis

Rheumatoid Arthritis

Germany, Belgium, Netherlands, Poland
Centre Hospitalier Universitaire Vaudois

Unknown

Combination Chemotherapy and Monoclonal Antibody Therapy in Treating Patients With Advanced Colorectal Cancer With Liver Metastases or Lung Metastases That Are Potentially Removable by Surgery

Colorectal Cancer | Metastatic Cancer

Switzerland
Livzon Pharmaceutical Group Inc.

Completed

Ilaprazole for the Treatment of Duodenal Ulcer in Chinese Patients (Phase 2)

Duodenal Ulcer

China
Kenta Biotech Ltd

Completed

Safety and Pharmacokinetics of KBPA-101 in Hospital Acquired Pneumonia Caused by O11 Pseudomonas Aeruginosa

Pneumonia | Ventilator Associated Pneumonia

Switzerland
Facet Biotech

Completed

Humanized Anti-IL-2 Receptor Monoclonal Antibody in Moderate-to-severe Ulcerative Colitis

Ulcerative Colitis | Inflammatory Bowel Disease | Gastrointestinal Disease

United States, Canada, Belgium
Amgen

Completed

Two Dose Schedules of Panitumumab in Subjects With Advanced Solid Tumors

Solid Tumors | Oncology | Tumors
Garden State Cancer Center at the Center for Molecular...

Unknown

Radiolabeled Monoclonal Antibody, Combination Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory B-Cell Cancer

Lymphoma | Leukemia

United States
Bradmer Pharmaceuticals Inc.

Unknown

Neuradiab® Combined With Bevacizumab (Avastin) Therapy in Patients With Recurrent Glioblastoma Multiforme

Brain Tumors

United States
Sheba Medical Center

Terminated

Treatment of Perianal Crohn's Disease, Combining Medical and Surgical Treatment.

Crohn's Disease

Israel
AstraZeneca

Completed

Efficacy and Safety Study of Esomeprazole vs Omeprazole to Treat Acute Non-Variceal Upper Gastrointestinal Bleeding

Gastrointestinal Hemorrhage

China
Garden State Cancer Center at the Center for Molecular...
National Cancer Institute (NCI)

Unknown

Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Relapsed or Refractory Non-Small Cell Lung Cancer

Lung Cancer

United States
Garden State Cancer Center at the Center for Molecular...
National Cancer Institute (NCI)

Unknown

Monoclonal Antibody Therapy in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer

Lung Cancer

United States
Hospices Civils de Lyon

Terminated

Elaboration of a Model for Predicting Efficacy of Monoclonal Antibodies (Cetuximab and Bevacizumab) in Patients With Colorectal Cancer and Liver Metastases

Neoplasm Metastasis | Colorectal Cancer

France
Peregrine Pharmaceuticals

Completed

Radiolabeled Monoclonal Antibody in Treating Patients With Glioblastoma Multiforme or Anaplastic Astrocytoma

Brain and Central Nervous System Tumors

United States
Hadassah Medical Organization

Unknown

Oral OKT3 in Combination With Beta-D-Glucosylceramide

Healthy

Israel, United States
Harrison Clinical Research
Merck KGaA, Darmstadt, Germany; AstraZeneca

Completed

Pharmocokinetic/Pharmacodynamic (PK/PD) Study of the Combination Cetuximab/Gefitinib

Head and Neck Cancer | Colorectal Cancer | Non Small Cell Lung Cancer (NSCLC)

Spain, Belgium
YM BioSciences

Terminated

Study of Nimotuzumab and Irinotecan in Metastatic Colorectal Cancer

Colorectal Cancer

Canada
Bristol-Myers Squibb

Completed

Drug Interaction Study With a Potential Alzheimer's Disease Compound

Alzheimer Disease

United States
Biosynexus Incorporated

Completed

Safety and Pharmacokinetics Study in Adults for the Prevention of S. Epidermidis Infection in Low Birth Weight Infants

Staphylococcal Sepsis

United States
AZ-VUB
KU Leuven; Universiteit Antwerpen; Erasme University Hospital

Completed

Extension of Phase II Therapeutic Trial With a Humanized Non-Mitogenic CD3 (ChAgly CD3) Monoclonal Antibody in Recently Diagnosed Type 1 Diabetic Patients

Diabetes Mellitus, Type 1

Belgium, Germany
University Hospital Birmingham NHS Foundation Trust

Completed

Anti-Cytokine Therapy for Vasculitis (ACTIVE)

Wegener's Granulomatosis | Microscopic Polyangiitis | Renal Limited Vasculitis

United Kingdom
National Institute of Arthritis and Musculoskeletal...

Terminated

Infliximab to Treat Children With Juvenile Rheumatoid Arthritis

Juvenile Rheumatoid Arthritis

United States
Sanofi

Completed

Insulin Glargine Benefits in Japanese Pts Outside of Japan (US or Brazil)

Diabetes Mellitus

Brazil
PDL BioPharma, Inc.

Completed

Study of Subcutaneous Daclizumab in Patients With Active, Relapsing Forms of Multiple Sclerosis

Multiple Sclerosis

United States, Canada
Grupo Oncológico para el Tratamiento y el Estudio...

Unknown

Consolidation Treatment With Y90-Ibritumomab Tiuxetan After R-CHOP Induction in High Risk Patients According to Follicular Lymphoma International Prognostic Index (FLIPI) With Follicular Lymphoma (GOTEL-FL1LC)

Follicular Lymphoma

Spain
Universita di Verona

Unknown

Combining Acitretin and Efalizumab in the Therapy of Chronic Plaque Psoriasis (CobAcE)

Chronic Plaque Psoriasis

Italy
University of Mississippi Medical Center
Novartis

Completed

Safety and Efficacy Study of Omalizumab Given Prior to Immunotherapy

Asthma

United States
Biotectid GmbH
University of Leipzig; Technische Universität Dresden

Completed

The Use of Anti-CD4 Monoclonal Antibody (mAb)-Fragment for the Imaging of Chronic Inflammation in Patients With Active Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis | Autoimmune Disease | Polyarthritis | Rheumatism

Germany
Peregrine Pharmaceuticals

Completed

Study of Bavituximab in Patients With Chronic Hepatitis C Virus Infection

Hepatitis C

United States
Peregrine Pharmaceuticals

Completed

Repeat-Dose Study of Bavituximab in Patients With Chronic Hepatitis C

Hepatitis C

United States
Abbott

Approved for marketing

Early Access Program of the Safety of Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects With Active Rheumatoid Arthritis (ReAct)

Rheumatoid Arthritis
Abbott

Approved for marketing

Study of the Human Anti-TNF Monoclonal Antibody in Patients With Active Rheumatoid Arthritis (CanAct)

Rheumatoid Arthritis
Abbott

Approved for marketing

Open Label Study to Assess Efficacy and Safety of the Fully Human Anti-TNF-Alpha Monoclonal Antibody Adalimumab (PROWD)

Rheumatoid Arthritis
Abbott

Completed

Study of the Safety and Efficacy of the Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects With Moderately to Severely Active Psoriatic Arthritis

Arthritis | Psoriatic
Medical University of Graz

Completed

Effects of Infliximab on Insulin Sensitivity and Beta Cell Function in Insulin Resistant Human Obesity

Obesity | Metabolic Syndrome | Insulin Resistance

Austria
Biosynexus Incorporated
GlaxoSmithKline

Completed

Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity Study in VLBW Neonates of BSYX-A110 (N003)

Staphylococcal Sepsis

United States

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