Search clinical trials for: Morphine Sulfate Controlled Release

Total 18050 results

University Health Network, Toronto
Canadian Society of Hospital Pharmacists

Withdrawn

Dosing Intervals of Opioid Medication for Chronic Pain

Chronic Pain

Canada
Grünenthal GmbH
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

A Study to Evaluate Tapentadol (CG5503) in the Treatment of Chronic Tumor-Related Pain Compared With Placebo and Morphine

Pain | Tumor

Austria, Bulgaria, Croatia, Czechia, France, Germany, Hungary, Italy, Moldova, Republic of, Poland, Romania, Russian Federation, Serbia, Slovakia, Spain, Sweden
Grünenthal GmbH
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Terminated

A Study to Evaluate the Effectiveness and Safety of CG5503 (Tapentadol) in the Treatment of Chronic Tumor Related Pain Compared With Placebo and Morphine

Pain | Cancer | Neoplasm

United States, Argentina, Chile, France, Latvia, Ukraine
Roxane Laboratories

Completed

Comparative Bioavailability Study of Morphine Sulfate Immediate Release and Controlled Release

Pain

United States
Egalet Ltd

Completed

A Efficacy and Safety Trial of Controlled Release (CR) Morphine in Cancer Patients

Pain | Cancer

Lithuania, Poland
Icahn School of Medicine at Mount Sinai
U.S. Department of Education

Completed

Effectiveness of Controlled-Release Morphine for Chronic Neuropathic Pain After Spinal Cord Injury

Neuropathic Pain | Spinal Cord Injury

United States
Pfizer

Completed

Abuse Potential Assessment of Intranasally Administered EMBEDA Compared To Morphine Sulfate Controlled Release And Placebo

Chronic Pain | Analgesia | Opioid-related Disorders | Narcotic Abuse
Pfizer

Completed

Abuse Potential of Orally Administered Crushed Embeda Compared to Crushed Controlled-Release Morphine and Placebo in Non-Dependent Recreational Opioid Users

Nondependent Opioid Abuse, Episodic

United States
Fujian Cancer Hospital

Not yet recruiting

IV PCA With or Without Continuous Dose vs Oral Opioid to Maintain Analgesia for Severe Cancer Pain After Successful Titration

Cancer Pain

China
Wayne State University

Recruiting

Cannabidiol, Morphine, Pain (CMP)

Chronic Pain | CBD

United States
Tetra Bio-Pharma
Cognitive Research Corporation

Recruiting

Inhaled Cannabinoids Versus Immediate-release Oral Opioids for the Management of Breakthrough Cancer Pain (REBORN)

Cancer | Breakthrough Cancer Pain

United States
Istanbul University

Completed

Comparison of Paravertebral Block and Subcostal Transversus Abdominis Plane Block in Laparoscopic Nephrectomy

Pain, Postoperative | Analgesia | Anesthesia

Turkey
Istanbul University

Completed

Comparison of Local Anesthetic Dose in Ipack Block Performed in Knee Arthroplasty Operations

Pain, Postoperative | Analgesia | Anesthesia

Turkey
Brigham and Women's Hospital
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Sensory Effects of Oral Opioid Treatment in Patients With Chronic Low Back Pain

Low Back Pain

United States
Lyndra Inc.
National Institute on Drug Abuse (NIDA)

Withdrawn

Study of LYN-014 in Individuals With Opioid Use Disorder Who Are Stable on Methadone Therapy

Opioid Use Disorder, Moderate
Massachusetts General Hospital

Completed

Effect of Combined Morphine and Duloxetine on Chronic Pain (Duloxetine)

Chronic Low Back Pain | Chronic Neck Pain

United States
Inonu University

Completed

Efficacy of Intravenous Paracetamol and Ibuprofen on Postoperative Pain and Morphine Consumption in Hysterectomy (ibupro-hyst)

Postoperative Pain Management

Turkey
Nova Scotia Health Authority
Canadian Institutes of Health Research (CIHR); Dalhousie University; Nova Scotia...

Terminated

Methadone in Neuropathic Pain

Chronic Neuropathic Pain

Canada
Norwegian University of Science and Technology
Maastricht University Medical Center; Fondazione IRCCS Istituto Nazionale dei... and other collaborators

Withdrawn

Nasal Fentanyl for Chronic Cancer Pain (NFCP-2)

Pain | Cancer
Actavis Inc.

Completed

Comparative Study to Evaluate KADIAN and Avinza in Healthy Adults

Healthy

United States
Pfizer

Terminated

Safety and Pharmacokinetic Study of EMBEDA in Children Ages 7-17 With Pain

Moderate-severe Pain

United States
Istanbul University

Completed

Integrated Pulmonary Index and Opioid Based Patient Controlled Analgesia

Brain Tumors

Turkey
Mundipharma (China) Pharmaceutical Co. Ltd

Unknown

A Study to Evaluate Buprenorphine Transdermal Patch in Chinese Subjects With Moderate to Severe Chronic Cancer Pain

Cancer Pain

China
Antonios Likourezos

Withdrawn

A Study Comparing Recurrent Use of MSIR, Percocet, and Vicodin at Discharge From the ED

Pain

United States
Eli Lilly and Company

Completed

A Study to Evaluate the Effect of Genotype on LY2216684

Depressive Disorder, Major

United States
Inonu University

Completed

Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Morphine Consumption in Lumbar Disc Surgery (ibuprofen)

Postoperative Pain Management

Turkey
Janssen Scientific Affairs, LLC

Withdrawn

An Open-label Evaluation of Tapentadol Extended Release (ER) in Participants With Moderate to Severe Chronic Pain After Conversion From Hydrocodone, Oxycodone Controlled Release (CR), and/or Morphine Sustained Release (SR)

Pain | Chronic Low Back Pain | Chronic Back Pain | Osteoarthritis Pain In The Hip or Knee

United States
University of Louisville
EKR Therapeutics, Inc

Terminated

Combination of Peripheral Nerve Block and DepoDur in Total Knee Joint Replacement

Arthroplasty, Replacement, Knee

United States
Brigham and Women's Hospital
National Institute on Drug Abuse (NIDA); Arthritis Foundation

Completed

Opioid Treatment for Chronic Low Back Pain and the Impact of Mood Symptoms

Depression | Anxiety | Degenerative Disc Disease | Chronic Low Back Pain

United States
Hopital Lariboisière

Unknown

Sustained-release Morphine Pharmacokinetics in Roux-en-Y Gastric Bypass Subjects (OBEMO2)

Bypass Complications

France
Mundipharma Research Limited

Completed

Study to Assess Pharmacokinetic (PK), Bioavailability & Food Effect of MR902 Compared With Immediate Release (IR) Morphine Sulphate Oral Solution

Opioid Substitution Treatment
Labtec GmbH

Withdrawn

A Safety and Efficacy Study of Sufentanil Transdermal System in Patients With Chronic Pain Due to Cancer

Chronic Pain
Pacira Pharmaceuticals, Inc
Registrat-Mapi

Terminated

A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301 (IMPROVE-Open)

Bowel Obstruction

United States
Pfizer

Completed

A Study of Embeda (Kadian NT, ALO-01) in Subjects With Pain Due to Osteoarthritis of the Hip or Knee

Osteoarthritis | Chronic Pain

United States
Pfizer

Completed

Study to Determine the Bioavailability, Pharmacodynamic Effects, and Safety of Whole and Crushed ALO-01 Compared to Morphine Sulfate Immediate Release (MSIR)

Healthy

Canada
Seyed Mehdi Pourafzali

Completed

Comparing the Analgesic Effect of Intravenous Acetaminophen and Morphine on Patients With Renal Colic Pain Reffering to the Emergency Department: A Randomized Controlled Trial

Renal Colic
Ranbaxy Inc.

Completed

Bioequivalence Study of Morphine Sulfate 60 mg Extended-Release Tablets Under Fasting Conditions

Healthy
Ranbaxy Inc.

Completed

Bioequivalence Study of Morphine Sulfate 60 mg Extended-Release Tablets Under Fed Conditions

Healthy
Pfizer

Completed

Evaluation of Risk Minimization, Assessment and Outcomes in Patients With Chronic Pain Taking Avinza (ACCESS 2008)

Pain

United States, Puerto Rico
University of Parma

Terminated

Controlled-Release Oxycodone For Postoperative Analgesia After Video-Assisted Thoracic Surgery

Pain, Postoperative | Anesthesia Recovery Period

Italy
Actavis Inc.

Completed

Comparison of One Morphine Sulfate Sustained-Release 200 mg Capsule With Two 100 mg KADIAN Capsules on Applesauce

Healthy

United States
Actavis Inc.

Completed

Comparison of One Morphine Sulfate Sustained-Release 200mg Capsule With Two 100 mg KADIAN Capsules Under Fed Conditions

Healthy

United States
Actavis Inc.

Completed

Comparison of Two KADIAN 10 mg Capsules to a KADIAN 20 mg Capsule Under Fed Conditions

Healthy

United States
Actavis Inc.

Completed

Comparison of One Morphine Sulfate Sustained-Release 200mg Capsule With Two 100 mg KADIAN Capsules Under Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

Comparison of Two KADIAN 10 mg Capsules to a KADIAN 20 mg Capsule Under Fasted Conditions

Healthy

United States
Archimedes Development Ltd

Completed

Efficacy and Safety Study of Nasalfent for Treatment of Breakthrough Cancer Pain in Patients Taking Regular Opioids

Cancers, Pain

United Kingdom
Institute of Child Health

Completed

Randomised Double Blind Placebo Controlled Cross Over Design of the Efficacy of Topical Morphine for Inflammatory Pain in Children With Epidermolysis Bullosa

Epidermylosis Bullosa

United Kingdom
CHU de Reims

Not yet recruiting

Evaluation of the Efficacy of the Addition of Magnesium Sulfate to Morphine on the Occurrence of Acute Urinary Retention Following Epidural Anesthesia for Cesarean Section. (EPIMAG)

Urinary Retention

France
National Cheng-Kung University Hospital

Not yet recruiting

Precise Endoscopic Application of Tranexamic Acid and Sucralfate in Gastrointestinal Bleeding: A Randomized Controlled Trial

Bleed Ulcer
University Hospital Schleswig-Holstein

Recruiting

Evaluation of Safety and Pharmacokinetics of Oral Controlled-ileal-release Nicotinic Acid (CIR-NA) Compared to Immediate-release Nicotinic Acid and Placebo in Healthy Subjects and Subjects With Prediabetes

Safety Issues | Pharmacokinetic

Germany

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