Search clinical trials for: NHS-IL12 M9241

Total 10282 results

National Cancer Institute (NCI)

Active, not recruiting

Phase II Trial of Combination Immunotherapy in Subjects With Advanced Small Bowel and Colorectal Cancers

Small Bowel Cancers | Colorectal Cancers

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Terminated

A Phase Ib Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of Avelumab in Combination With M9241(NHS-IL12) (JAVELIN IL-12) (COMBO)

Advanced Solid Tumors

Spain, United States, Netherlands, Hungary, Italy, France, Belgium
National Cancer Institute (NCI)

Terminated

Immune Checkpoint Inhibitor M7824 and the Immunocytokine M9241 in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Advanced Pancreas Cancer

Pancreatic Neoplasms | Pancreatic Cancer | Metastatic Pancreatic Cancer | Histologically or Cytologically Confirmed Pancreatic Cancer | Unresectable or Borderline Resectable Pancreatic Cancer

United States
National Cancer Institute (NCI)

Recruiting

A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers

Cervical Cancer | Vulvar Cancer | Colon Cancer | Anal Cancer | Vaginal Cancer | Oropharyngeal Cancer | Penile Cancer | HPV | Human Papillomavirus | Neck Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies

Cervical Cancer | Anal Cancer | Oropharyngeal Cancer | HPV Cancers | Vulvar, Vaginal, Penile, Rectal Cancer

United States
National Cancer Institute (NCI)

Recruiting

NHS-IL12 Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma

Kaposi Sarcoma

United States
M.D. Anderson Cancer Center

Withdrawn

Immunotherapy (NHS-IL12 & Bintrafusp Alfa) and Radiation Therapy for the Treatment of Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer, the REINA Trial

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Breast Carcinoma | Hormone Receptor Positive Breast Adenocarcinoma | Metastatic HER2 Negative Breast Adenocarcinoma

United States
National Cancer Institute (NCI)

Completed

NHS-IL12 for Solid Tumors

Epithelial Tumors, Malignant | Epithelial Neoplasms, Malignant | Malignant Mesenchymal Tumor

United States
National Cancer Institute (NCI)

Recruiting

Bintrafusp Alfa (M7824) and NHS-IL12 (M9241) Alone and in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Metastatic Non-Prostate Genitourinary Malignancies

Urogenital Neoplasms | Bladder Cancer | Urothelial Cancer | Genitourinary Cancer | Urogenital Cancer

United States
University of St Andrews
Swansea University; University of Surrey; Chief Scientist Office of the Scottish... and other collaborators

Unknown

Mini-AFTERc Intervention for Fear of Cancer Recurrence (Mini-AFTERc)

Breast Cancer | Fear of Cancer

United Kingdom
Queen Margaret University
NHS Lothian

Terminated

Health After Birth Intervention Trial (HABIT)

Obesity

United Kingdom
Akeso
Akeso Tiancheng, Inc

Completed

A Clinical Study of AK101 in Subjects With Moderate to Severe Plaque Psoriasis

Plaque Psoriasis

China
King's College London
BitJam

Recruiting

Online Peer Support in Long-term Conditions

Subthreshold Depression | Long-term Physical Health Conditions

United Kingdom
Centro de Diagnostico Auditivo de Cuiaba

Completed

Results of a Program of Newborn Hearing Screening (NHS) in Cuiaba-Brazil

Showing the Results of a Program of NHS in Cuiaba_ Brazil

Brazil
Akeso
Akeso Tiancheng, Inc

Completed

Clinical Study of AK101 in Subjects With Moderate to Severe Plaque Psoriasis

Plaque Psoriasis

China
Community Pharmacology Services Ltd
Keneric Healthcare

Not yet recruiting

Diabetic Foot Ulcer Research Study

Diabetic Foot Ulcer | Diabetic Foot Ulcer Neuropathic | Diabetic Foot Ulcer Ischemic
National Cancer Institute (NCI)

Recruiting

Enzalutamide and M9241 in PET Positive Recurrent Prostate Cancer (pprPC) Without Testosterone Lowering Therapy

Recurrent Prostate Cancer | Prostate Cancer | PET Positive

United States
London South Bank University
NHS Lambeth; NHS Southwark CCG; Allen Carr Easyway

Completed

Study Comparing Two Stop Smoking Intervention Efficacies

Smoking Cessation

United Kingdom
University of Manchester
University of Nottingham; Queen Mary University of London; Manchester University... and other collaborators

Completed

What Are the Benefits and Harms of Risk Stratified Screening in the NHS Breast Screening Programme: Study Protocol

Breast Cancer

United Kingdom
European School of Osteopathy
Sutherland Cranial College of Osteopathy; Sutherland Society

Unknown

Cranial Osteopathy in Infantile Colic

Infantile Colic

United Kingdom
Shenzhen Second People's Hospital
The Pregene (ShenZhen) Biotechnology Company, Ltd.

Unknown

EGFR-IL12-CART Cells for Patients With Metastatic Colorectal Cancer (EGFRCART)

Metastatic Colorectal Cancer

China
AirEmail Holdings Limited

Recruiting

NHS Staff Digital Wellbeing Via AirEmail (NHS DigiWell)

Burnout, Professional | Communication Research | Work Related Stress | Well-Being, Psychological | Technostress

United Kingdom
Manchester University NHS Foundation Trust
University of Manchester; National Institute for Health Research, United Kingdom

Active, not recruiting

Manchester Intermittent Diet in Gestational Diabetes Acceptability Study (MIDDAS-GDM)

Diabetes | Pregnancy Related | Gestational Diabetes | Gestational Diabetes Mellitus in Pregnancy | Intermittent Fasting | Diabetes in Pregnancy

United Kingdom
Washington University School of Medicine
Operation Food Search Inc.

Recruiting

Fresh RX: NHS 2020

Premature Birth | Birth Weight | Post Partum Depression | Fetal Complications | Health Care Utilization | Food Deprivation | Housing Problems | Nutrition Deficiency Due to Insufficient Food

United States
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Active, not recruiting

Burden for STaff Working in the NHS (COST-NHS)

COVID-19 | Mental Health Burden

United Kingdom
University of Plymouth
National Institute for Health Research, United Kingdom

Not yet recruiting

Investigating Remote Access, Group-based Functional Imagery Training in the Community

Quality of Life | Weight Loss | Health Economics
Imperial College London

Active, not recruiting

Investigating the Physiological Effects of Weight Loss on Male Fertility

Obesity | Weight Loss | Male Infertility

United Kingdom
National Cancer Institute (NCI)

Recruiting

T-Cell Clonality After Stereotactic Body Radiation Therapy Alone and in Combination With the Immunocytokine M9241 in Localized High- and Intermediate-Risk Prostate Cancer Treated With Androgen Deprivation Therapy

Cancer Of Prostate

United States
National Cancer Institute (NCI)

Recruiting

M9241 in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer or Intrahepatic Cholangiocarcinoma

Colorectal Neoplasms | Colorectal Cancer | Cholangiocarcinoma | Bile Duct Cancer | Bile Duct Neoplasms | Metastatic Colorectal Cancer (Mcrc) | Intrahepatic Cholangiocarcinoma (Icc) | Intrahepatic Bile Duct Cancer

United States
UMC Utrecht

Not yet recruiting

Multinational Glanzmann Study (Glanzmann-NHS)

Glanzmann Thrombasthenia
Assiut University

Unknown

Neonatal Hearing Screening in Assiut Hospital

Neonatal Hearing Impairment
Sonnet BioTherapeutics

Completed

Study of SON-1010 (IL12-FHAB) in Healthy Adults

Healthy Adult

Australia
King's College London
NHS Devon ICB

Completed

Midwifery Retention Project

Retention/Attrition of Midwives

United Kingdom
Sykehuset Innlandet HF
Helse Sor-Ost; Norwegian Department of Health and Social Affairs

Completed

Collaboration Between Department of Old Age Psychiatry and Nursing Homes (SAM-AKS)

Behavioral Symptoms | Dementia | Alzheimer's Disease | Agitation

Norway
Hull University Teaching Hospitals NHS Trust

Completed

Assessing Frailty in Elderly Patients Who Have Ischemic Heart Disease (FRAIL_HEART)

Frail Elderly

United Kingdom
Shanghai Virogin Biotech Co., Ltd.

Recruiting

A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Biologic Effect of VG2025 in Patients With Solid Tumors

Advanced Malignant Solid Tumor

China
University of Nottingham

Unknown

RCT of the Effectiveness of Big White Wall Compared to Other Online Support (REBOOT)

Depression | Anxiety

United Kingdom
University of Athens

Unknown

Evaluation of Nocturnal Hypertension and Correlation With Target-Organ Damage

Nocturnal Hypertension

Greece
OncoSec Medical Incorporated

Terminated

Phase II Intratumoral IL12 Plasmid Electroporation in Cutaneous Lymphoma (CTCL)

Mycosis Fungoides (MF) | Cutaneous T Cell Lymphomas (CTCL)

United States
Nottingham University Hospitals NHS Trust
University of Nottingham

Completed

Exploring Efficacy, Cost Effectiveness and Experiences Related to Adherence of Different Bisphosphonate Regimens for the Prevention of Osteoporotic Fragility Fractures. (BLASTOFF)

Osteoporosis

United Kingdom
Fundación Pública Andaluza para la gestión de la...

Unknown

Study for the Efficacy and Security Analysis in the Protection of Ileocolic Anastomosis Conducted in Laparoscopic Right Hemicolectomy Because of Colon Cancer, Using a NHS-PEG Coated Collagen Patch. (ANASTOPATCH)

Adenocarcinoma Colon

Spain
Imperial College Healthcare NHS Trust

Unknown

Non-invasive Continuous Cardiac Output Monitoring in Preterm Infants Study (NICCOM)

Blood Pressure | Cardiac Output, Low | Cardiac Output, High

United Kingdom
University of Birmingham
University of Oxford; University of Edinburgh; The Brain Tumour Charity; Genomics...

Recruiting

Tessa Jowell BRAIN MATRIX - Platform Study (BRAIN MATRIX)

Glioma

United Kingdom
Heart of England NHS Trust
University of Warwick; University of Birmingham

Completed

Acute Kidney Outreach to Reduce Deterioration and Death (AKORDD) (AKORDD)

Acute Kidney Injury

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

Femtosecond Laser Assisted Cataract Surgery in The NHS

Cataract | Surgery
Prof. Dr. Matthis Synofzik

Recruiting

RFC1 Natural History Study (RFC1-NHS)

Ataxia

Germany, Italy, Australia, Brazil, France, New Zealand, Turkey
Assiut University

Unknown

Neonatal Hearing Screening at Neonatal Intensive Care Unit

Hearing Loss

Egypt
The Leeds Teaching Hospitals NHS Trust

Unknown

MOTIVATE AF Motivational Support for Patients With Atrial Fibrillation to Promote Weight Loss (MOTIVATE AF)

Atrial Fibrillation
CNBG-Virogin Biotech (Shanghai) Ltd.

Recruiting

Clinical Study of VG161 in Subjects With Advanced Malignant Solid Tumors

Advanced Malignant Solid Tumor

China
Public Health England

Completed

Randomized Controlled Trial on Uptake of NHS Health Checks

Cardiovascular Diseases

United Kingdom

Search clinical trials for: NHS-IL12 M9241

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