Search clinical trials for: Neurotoxicity

Total 239 results

M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Haloperidol and Lorazepam for Delirium in Patients With Advanced Cancer

Advanced Cancers

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

Brain and Central Nervous System Tumors | Neurotoxicity

United States
Emergent BioSolutions

Enrolling by invitation

BT-011 Pharmacokinetics of Botulism Antitoxin Heptavalent in Pediatric Patients

Botulism
Vanderbilt University Medical Center

Completed

Effect of Antibiotic Choice On ReNal Outcomes (ACORN) (ACORN)

Sepsis | AKI | Neurotoxicity

United States
University of California, Davis
Veloxis Pharmaceuticals

Completed

A Pilot Study to Evaluate Impact on Neurological Side Effects (Cognition, Memory, and Tremor) in Elderly (Age>65) Patients

Toxicity | Neurotoxicity | Kidney Transplant; Complications | Drug Toxicity

United States
Henan Cancer Hospital

Completed

A Study of Monosialic Gangliosides to Prevent Albumin-bound Paclitaxel Neurotoxicity

Early Breast Cancer

China
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients With Previously Untreated Mantle Cell Lymphoma

Lymphoma | Neurotoxicity | Therapy-related Toxicity

United States, Canada
Unity Health Toronto

Terminated

Phenobarbital for Severe Acute Alcohol Withdrawal Syndrome (PHENOMANAL)

Alcohol Withdrawal | Alcohol Withdrawal Delirium | Alcohol Withdrawal Seizures

Canada
Murdoch Childrens Research Institute
Baylor College of Medicine; Children's Hospital of Philadelphia; Boston Children... and other collaborators

Active, not recruiting

A Study to Compare the Long-term Outcomes After Two Different Anaesthetics (TREX)

Child Development | Anesthesia | Neurotoxicity

United States, Australia, Italy, Spain
Washington University School of Medicine
McDonnell Center; Paula and Roger Riney Blood Cancer Research

Terminated

Serum Neurofilament Light (NfL) as a Marker for Brain Injury in Individuals Undergoing Chimeric Antigen Receptor-modified T Therapy

Neurotoxicity

United States
Cairo University
Misr International University

Completed

Comparison of Weekly Versus Every Three Weeks of Carboplatin Plus Paclitaxel in Patients With Advanced Epithelial Ovarian Cancer

Advanced Epithelial Ovarian Cancer

Egypt
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma

Lymphoma | Neurotoxicity | Radiation Toxicity | Cognitive/Functional Effects | Chemotherapeutic Agent Toxicity

United States, Israel
Hospices Civils de Lyon

Completed

CICLOPS Immune Checkpoint Inhibitors Neurotoxicity: Long-term Outcomes, Predictors, and Survival. (LOPF - NIRAES)

Paraneoplastic Syndromes

France
Comenius University

Enrolling by invitation

Influence of General Anesthesia on the Dynamic Changes in Brain Damage Markers During and After Craniosynostosis Operations in Infancy (TAnBrainDam)

Anesthesia | Craniosynostosis

Slovakia
Pedro Gamito
Universidade Lusófona de Humanidades e Tecnologias

Completed

Health Mobile Cognitive Stimulation in Alcohol Use Disorder

Alcohol Dependence | Alcohol-Induced Disorders, Nervous System

Portugal
Seoul National University Hospital

Active, not recruiting

Association Between Anesthetic Drugs for General Anesthesia and Postoperative Intelligence/Behavioral Assessment Results in Children

Anesthesia and Neurotoxicity

Korea, Republic of
Dartmouth-Hitchcock Medical Center
Disarm Therapeutics

Completed

Biomarkers in Chemotherapy-Induced Peripheral Neurotoxicity (CIPN)

CIPN - Chemotherapy-Induced Peripheral Neuropathy

United States
Groupe Hospitalier Pitie-Salpetriere

Completed

a Vigibase Pharmacovigilance Study of ENzalutamide Drug-induced neurotoxicitY (VENDY)

Epilepsy | Prostate Cancer | Neuropathy | Encephalopathy

France
National Cancer Institute, Naples

Active, not recruiting

Study Comparing Weekly Versus Every 3 Week Chemotherapy in Patients With Ovarian Cancer (MITO-7)

Ovarian Cancer

Italy
Universitas Sumatera Utara

Completed

Neuroprotective Effects of ACTH4-10PRO8-GLY9-PRO10

Ketamine-Induced Neurotoxicity

Indonesia
Centre Hospitalier Universitaire, Amiens

Completed

Neurotoxicity Evaluation of Beta-lactams in Intensive Care Unit and Identification of the Risk Factors (NebuLar)

Sepsis | Acute Kidney Injury | Neurotoxicity | Critical Care | Therapeutic Drug Monitoring | Beta Lactams
Henan Cancer Hospital

Withdrawn

GM1 in the Treatment of Neurotoxicity Induced by Albumin-bound Paclitaxel

Early Breast Cancer

China
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy

Colorectal Cancer | Neurotoxicity | Neuropathy | Chemotherapeutic Agent Toxicity

United States, Puerto Rico
National Cheng-Kung University Hospital

Active, not recruiting

To Study the Individual Variants of Chemotherapy-Induced Neurotoxicity

Neurotoxicity Syndromes

Taiwan
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery

Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Neurotoxicity | Radiation Toxicity | Cognitive/Functional Effects

United States
Rijnstate Hospital

Terminated

N-AcetylCysteine vs. Placebo to Prevent Neurotoxicity Induced by Platinum Containing Chemotherapy (NAC-PNP)

Carcinoma, Non-Small-Cell Lung | Mesothelioma | Carcinoma, Small Cell Lung

Netherlands
Memorial Sloan Kettering Cancer Center
Rutgers University

Completed

Using a Novel Functional MRI Technique to Evaluate for Neurotoxicity

Central Nervous System Lymphoma

United States
BioNumerik Pharmaceuticals, Inc.
Lantern Pharma Inc. became Sponsor of Tavocept (BNP7787) IND 051014 as of...

Completed

Evaluation of BNP7787 for the Prevention of Neurotoxicity in Metastatic Breast Cancer Patients Receiving Weekly Paclitaxel

Breast Neoplasms | Breast Diseases | Metastases, Neoplasm
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Evaluate the Safety and Pharmacokinetics of NTM-1633 vs Placebo Administered Intravenously in Healthy Adults

Botulism

United States
Fundacion SEIMC-GESIDA
Janssen-Cilag, S.A.

Completed

A Clinical Trial to Evaluate the Reversibility of Abacavir/Lamivudine/Dolutegravir CNS-Related Neurotoxicity After Switching to Tenofovir/Alafenamide/Emtricitabine/Darunavir/Cobicistat (TAF/FTC/DRV/c) (DETOX)

HIV Infections

Spain
Ministry of Public Health, Democratic Republic...
National Institutes of Health (NIH); Oregon Health and Science University; National... and other collaborators

Completed

Cassava Intervention Project

Neurotoxicity Syndrome, Cassava | Neurotoxicity Syndrome, Cyanate | Neurotoxicity Syndrome, Cyanide | Neurotoxicity Syndrome, Thiocyanate

Congo, The Democratic Republic of the
University Hospital, Montpellier

Completed

EEG Encephalopathy Patterns in Immune Effectors Cells-associated Neurotoxicity Syndrome (ICANS)Lay Language

Neurotoxicity | Immune Effector Cell Encephalopathy

France
Mansoura University

Completed

ONSD and Neurotoxicity in Liver Transplant

Liver Transplant; Complications

Egypt
Tanta University

Active, not recruiting

Neurotoxicity of Anesthesia in Middle Aged Patients

Anesthesia; Adverse Effect

Egypt
University Hospital, Toulouse

Completed

Evaluation of the Improvement of Quality of Life of Patients Suffering From Hailey Hailey or Darier Disease After Injections of Botulism Toxin Into Large Folds. (ToxHD)

Darier Disease | Hailey-Hailey Disease
Jazz Pharmaceuticals

Terminated

A Safety and Efficacy Study of Defibrotide in the Prevention of Chimeric Antigen Receptor-T-cell-associated Neurotoxicity

Neurotoxicity Syndromes | DLBCL

United States
Mayo Clinic
National Heart, Lung, and Blood Institute (NHLBI); National Institute on Aging...

Completed

Neurotoxicity and Cardiotoxicity in Total Joint Arthroplasty

Pain | Total Hip Replacement | Metallosis | Total Knee Replacement

United States
Gerald Higa, PharmD.

Terminated

Study to Assess Prevention of Oxaliplatin-induced Neurotoxicity Through Vitamin D Pathway

Neurotoxicity

United States
Helse Nord-Trøndelag HF

Completed

Somatic Disease Among Alcohol Abusers in an Out-day Patients' Clinic

Liver Failure | HEART DISEASE | DEPRESSIVE DISORDER | Alcoholic Neuropathy

Norway
Sun Yat-sen University

Completed

Effect of GM1 in Prevention of Taxanes Induced Neurotoxicity in Operable Breast Cancer

Breast Cancer

China
California Department of Public Health

Completed

Tolerability and Immunogenicity of rBV A/B for the Production of BabyBIG®

Botulism

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Bortezomib, Thalidomide, and Dexamethasone After Melphalan and Stem Cell Transplant in Treating Patients With Stage I-III Multiple Myeloma

Neurotoxicity | Multiple Myeloma and Plasma Cell Neoplasm

United States
University of South Florida
National Cancer Institute (NCI)

Completed

Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor

Fatigue | Brain and Central Nervous System Tumors | Neurotoxicity | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment

United States
University of South Florida
National Cancer Institute (NCI); Children's Oncology Group

Completed

Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer

Sarcoma | Lymphoma | Kidney Cancer | Leukemia | Neurotoxicity | Peripheral Neuropathy

United States
Universitaire Ziekenhuizen KU Leuven

Active, not recruiting

Association of Cefepime Trough Levels With Clinical Efficacy and Neurotoxicity in Patients With Febrile Neutropenia

Pharmacokinetics | Pharmacodynamics | Cefepime

Belgium
Oncologia Medica dell'Ospedale Fatebenefratelli
Mario Negri Institute for Pharmacological Research

Completed

PAINTER: Polymorphism And INcidence of Toxicity in ERibulin Treatment

Metastatic Breast Cancer | Toxicity | Neurotoxicity | Adverse Drug Event | Drug Toxicity

Italy
Oulu University Hospital

Unknown

Assessment of Chemotherapy-induced Peripheral Neurotoxicity Using a Point-of-care Nerve Conduction Study Device (APPS)

Cancer

Finland
Novartis Pharmaceuticals

Completed

Open Label, Safety, Tolerability and Efficacy of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias

Parkinson Disease | Dyskinesia, Drug-Induced | Levodopa

Italy, United States, Australia, France, Germany, Canada
Wake Forest University Health Sciences

Withdrawn

Telemedicine for Early Detection of Cytokine Release Syndrome and Neurotoxicity

Follicular Lymphoma | Diffuse Large B Cell Lymphoma | High-grade B-cell Lymphoma | Primary Mediastinal Large B Cell Lymphoma | Large B-cell Lymphoma
The Hospital for Sick Children
Canadian Institutes of Health Research (CIHR); Canadian Cancer Society (CCS); C17 Council and other collaborators

Completed

N-PhenoGENICS: Neurocognitive-Phenome, Genome, Epigenome and Nutriome In Childhood Leukemia Survivors (NPG)

Childhood Leukemia Survivors

Canada

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