Somatic Disease Among Alcohol Abusers in an Out-day Patients' Clinic

Somatic Disease Among Alcohol Abusers in an Out-day Patients' Clinic. A Neglected Area

Alcohol abuse is associated with a variety of clinical diseases, but studies on prevalence of different somatic diseases among alcohol abusers are lacking. Studies on populations in an out-day patients' clinic are also lacking.

The investigators aim to study somatic health standard in an out-day patients' clinic population of alcohol abusers, with regard to prevalence of different kinds of somatic diseases, and how the interaction of somatic and psychiatric treatment can influence on patients quality of life. Clinical examination including blood samples and echocardiographic examinations in all participants, other additional examinations (as x-ray, CT or MRI if indicated by clinical findings).

Study Overview

• Status: Completed
• Conditions: Liver Failure; HEART DISEASE; DEPRESSIVE DISORDER; Alcoholic Neuropathy
• Intervention / Treatment: Other: Psychiatric and somatic examinations and ,if clinical indicated, treatment

Detailed Description

Retrospective methods will be used to study former somatic disease, cross-section design to study present somatic disease and prospective design to study quality of life, psychiatric and somatic health after combination of psychiatric and somatic examinations and treatment.

• Study Type: Observational
• Enrollment (Actual): 150

Contacts and Locations

Study Locations

• Norway
  • Levanger, Norway, N-7600
    • Levanger Hospital, Dep. of Psychiatry

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Alcohol abusers referred to the out-day patients' clinic at Dep. of Psychiatry, Levanger Hospital, Norway

Description

Inclusion Criteria:

• Alcohol abusers reffered to the out-day patients' clinic at Dep. of Psychiatry, Levanger Hospital, Norway

Exclusion Criteria:

• Not consenting to participate
• Not able to consent

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Other

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Out-day patients' clinic; Alcohol abusers referred to out-day patients' clinic which consent to participate in the study	Other: Psychiatric and somatic examinations and ,if clinical indicated, treatment; Patients referred to the clinic will be given optimal treatment for revealed psychiatric and/or somatic disease including conversational therapy, and if indicated therapeutic interventions with respect to any kind of disease.
Control; Control group for the cardiac arm of the study will be matched controls from the Nord-Trøndelag Health Study (HUNT)

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Prevalence of different kinds of somatic disease	Prevalence of somatic disease at study attendance of any kind, specified for heart disease, gall- and liver disease, neuropathic disease.	3 months after inclusion

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Prevalence of former somatic disease	Prevalence of former somatic disease investigated by anamnestic examination, search in patient journals and communication with the patients community health service.	3 months after inclusion
Outcome of psychiatric and somatic treatment of alcohol abusers	Quality of life and score of somatic and psychiatric health 1 year after inclusion	1 year after stopped inclusion

Collaborators and Investigators

• Sponsor: Helse Nord-Trøndelag HF
• Investigators: Principal Investigator: Erling Dalen, MD, Helse Nord-Trøndelag HF

Publications and helpful links

General Publications

• Moss M, Parsons PE, Steinberg KP, Hudson LD, Guidot DM, Burnham EL, Eaton S, Cotsonis GA. Chronic alcohol abuse is associated with an increased incidence of acute respiratory distress syndrome and severity of multiple organ dysfunction in patients with septic shock. Crit Care Med. 2003 Mar;31(3):869-77. doi: 10.1097/01.CCM.0000055389.64497.11.
• Moss M, Burnham EL. Alcohol abuse in the critically ill patient. Lancet. 2006 Dec 23;368(9554):2231-42. doi: 10.1016/S0140-6736(06)69490-7.
• Awtry EH, Philippides GJ. Alcoholic and cocaine-associated cardiomyopathies. Prog Cardiovasc Dis. 2010 Jan-Feb;52(4):289-99. doi: 10.1016/j.pcad.2009.11.004.
• Dalen E, Holmen J, Nordahl HM. Somatic health of patients at an outpatient clinic for substance abuse. Tidsskr Nor Laegeforen. 2015 Jan 27;135(2):127-31. doi: 10.4045/tidsskr.13.0801. eCollection 2015 Jan 27. English, Norwegian.

Study record dates

Study Major Dates

• Study Start: March 1, 2010
• Primary Completion (Actual): December 1, 2012
• Study Completion (Actual): May 1, 2013

Study Registration Dates

• First Submitted: March 4, 2010
• First Submitted That Met QC Criteria: March 4, 2010
• First Posted (Estimate): March 5, 2010

Study Record Updates

• Last Update Posted (Actual): November 9, 2021
• Last Update Submitted That Met QC Criteria: November 5, 2021
• Last Verified: November 1, 2021

More Information

Terms related to this study

• Keywords: depression; heart failure; liver; neuropathy
• Additional Relevant MeSH Terms: Mental Disorders; Chemically-Induced Disorders; Digestive System Diseases; Hepatic Insufficiency; Cardiovascular Diseases; Nervous System Diseases; Alcohol-Related Disorders; Substance-Related Disorders; Mood Disorders; Liver Diseases; Neuromuscular Diseases; Peripheral Nervous System Diseases; Poisoning; Alcohol-Induced Disorders; Polyneuropathies; Neurotoxicity Syndromes; Alcohol-Induced Disorders, Nervous System; Heart Diseases; Depressive Disorder; Liver Failure; Alcoholic Neuropathy
• Other Study ID Numbers: LE_ARP_Somatic_AlcoholAddicts