Search clinical trials for: Next-Generation Sequencing (NGS)

Total 1178 results

Yizhuo Zhang

Recruiting

Clinical Value of Next Generation Sequencing in Chinese Childhood Solid Tumors

Pediatric, Solid Tumors, NGS

China
Chang Gung Memorial Hospital

Recruiting

Investigation and Diagnosis of the Chromosome Variation in Donated/Abandoned Blastocyst

Recurrent Miscarriage | Chromosome Translocation | Genetic Disorders in Pregnancy

Taiwan
Rennes University Hospital

Completed

Retrospective Study Using Next Generation Sequencing (NGS) on Biological Samples to Improve Genetic Counseling for Patients With Previously Explored Craniofacial Midline Defects. (EXOMEDIANE)

Holoprosencephaly

France
The First Hospital of Jilin University

Not yet recruiting

Performance Study of Targeted Sequencing Technology for VAP

VAP - Ventilator Associated Pneumonia
University Hospital Tuebingen
Charite University, Berlin, Germany; RWTH Aachen University; Medical University...

Not yet recruiting

Initiative for Clinical Long-read Sequencing (IonGER)

Genetic Predisposition

Germany
Fujian Cancer Hospital

Unknown

Next-generation Sequencing of Small Cell Lung Cancer to Identify Susceptibility Gene and to Assess Treatment

SCLC
National Cancer Institute (NCI)

Recruiting

A Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymphoblastic Leu...

Acute Lymphoblastic Leukemia | B-All

United States
The Belgian Society of Medical Oncology
Roche Pharma AG; Foundation Medicine; Sciensano

Recruiting

A Study to Examine the Value of Broad Agnostic Next Generation Sequencing (NGS) Panel Testing Versus Reimbursed Organ-directed NGS: a Belgian Precision Study of the BSMO in Collaboration With the Cancer Center

Metastatic Cancer | Local Tumor Invasion

Belgium
Shanghai Children's Hospital
Children's Hospital of Chongqing Medical University; Northwest Women's and... and other collaborators

Not yet recruiting

Newborn Sequencing Screening in China

Newborns
National Cancer Institute, Naples

Recruiting

Molecular Data and Their Correlations With Clinical Outcomes in Gynecological Cancer Patients. (GYNGER)

Gynecologic Cancer

Italy
Children's Hospital of Chongqing Medical University
The First Hospital of Jilin University; Xuzhou Maternity and Child Health Care... and other collaborators

Completed

The Pilot Study of High-throughput Sequencing in Neonatal Birth Defects

Genetic Diseases | Birth Defect | Congenital Malformation | Multiple Malformation | Newborn; Fit

China
PETHEMA Foundation

Completed

Diagnostic Platform to Perform Centralized and Standardized Rapid Molecular Diagnosis by Next Generation Sequencing (NGS) in Patients Diagnosed With Acute Myeloid Leukemia.

Acute Myeloid Leukemia

Spain
Xianmin Song, MD

Recruiting

Next Generation Sequencing（NGS）Monitors Minimal Residual Disease（MRD）in Allo-PBSCT Patients

NGS Monitor MRD

China
Shanghai Chest Hospital
Geneplus-Beijing Co. Ltd.; Guangzhou Burning Rock Medical Examination Institute... and other collaborators

Unknown

A Prospective Study to Evaluate the Consistency of Next-Generation Sequencing(NGS)-Panels by Using Malignant Hydrothorax Form NSCLC

NSCLC | Malignant Hydrothorax

China
A2 Biotherapeutics Inc.
Tempus AI

Recruiting

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing (BASECAMP-1)

Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Neoplasms | Ovarian Cancer | NSCLC | Non Small Cell Lung Cancer | Mesothelioma | Mesothelioma, Malignant | Pancreas Cancer | Ovarian Carcinoma | Solid Tumor, Adult | CRC | Mesothelioma; Lung

United States
Shanghai Children's Hospital
Children's Hospital affiliated to Chongqing Medical University; Xuzhou maternal...

Not yet recruiting

NGS in the Diagnosis of Neonatal Diseases

Premature Infants | NICU Infants | Conventional NBS-positive Infants
AnchorDx Medical Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; The First Affiliated... and other collaborators

Active, not recruiting

Diagnostic and Monitoring Significance of ctDNA Methylation Analysis by NGS in Benign and Malignant Pulmonary Nodules

Pulmonary Nodules

China
Rady Pediatric Genomics & Systems Medicine Institute

Recruiting

An Adaptive Clinical Trial of BeginNGS Newborn Screening for Hundreds of Genetic Diseases by Genome Sequencing (BeginNGS)

Genetic Disease

United States
National Cancer Center, Japan

Recruiting

Asian Multicenter Prospective Study of ctDNA Sequencing (A-TRAIN)

Cervical Cancer | Nasopharyngeal Carcinoma | Ovarian Cancer | Triple Negative Breast Cancer | Endometrial Cancer | Ovarian Clear Cell Carcinoma

Japan, Korea, Republic of, Malaysia, Thailand, Philippines, Singapore, Taiwan, Vietnam
Jagiellonian University

Recruiting

Endometriosis and Peritoneal Dysbiosis

Endometriosis | Infertility Unexplained

Poland
University Hospital Tuebingen

Recruiting

Mitochondrial Diseases - Long-read Genome and Transcriptome Sequencing in Cases Unresolved After Short-read Genomics

Rare Diseases | Genetic Predisposition

Germany
Na Homolce Hospital
Czech Academy of Sciences

Completed

miRNA in Patients With Thoracic, Abdominal and Intracranial Aneurysms (miRNA)

Vascular Aneurysm

Czechia
Affiliated Hospital of Nantong University
Second Affiliated Hospital of Nantong University; Children's Hospital of Fudan... and other collaborators

Recruiting

Clinical Precise Diagnosis and Treatment in the Kawasaki Disease

Kawasaki Disease

China
Fudan University

Unknown

Use of Plasma ctDNA Methylation Haplotypes in Detecting Local Residual or Lymph Node Metastasis

Colorectal Cancer | Lymph Node Metastases

China
Fujian Cancer Hospital

Unknown

Next-generation Sequencing in Gastrointestinal Cancer

Gastrointestinal Cancer

China
China Medical University, China

Unknown

Sensitivity and Specificity of NGS in Detecting bMSI in Patients With Gastric, Duodenal and Small Intestinal Cancer

Gastrointestinal Cancer

China
Yunfeng Hou

Not yet recruiting

The Value of mNGS in Diagnosis of Pulmonary Infection

Pulmonary Infection
University Health Network, Toronto
Women's College Hospital; Jewish General Hospital; IWK Health Centre; British Columbia... and other collaborators

Recruiting

Cell-free DNA in Hereditary And High-Risk Malignancies (CHARM)

Hereditary Cancer Syndrome

Canada
Fudan University
Southern Medical University, China

Completed

The Implication of Plasma ctDNA Methylation Haplotypes in Detecting Colorectal Cancer and Adenomas

Colorectal Cancer | Adenoma

China
Imperial College London Diabetes Centre

Unknown

Genetic Causes of Hypercholesterolaemia in the Emirati Population

Familial Hypercholesterolemia

United Arab Emirates
MicroGenDX

Recruiting

Next Generation Sequencing Versus Traditional Cultures for Clinically Infected Penile Implants: Impact of Culture Identification on Outcomes

Infections | Penile Implantation

United States
Memorial Sloan Kettering Cancer Center
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab Following Surgery in Patients With Microsatellite Instability High (MSI-H) Solid Tumors

Solid Tumors | Identified by NGS, PCR or IHC

United States
University Hospital Tuebingen

Recruiting

Genetic Causes of Discrepant Clinic in Monogenic Twins (DISCO-TWIN)

Genetic Predisposition to Disease | Rare Diseases

Germany
University Hospital Tuebingen

Recruiting

Diagnostic Research in Patients With Rare Diseases - Solving the Unsolved Rare Diseases (DiRiP-RD)

Rare Diseases | Genetic Predisposition

Germany
Karl Landsteiner Institute for Lung Research and...

Recruiting

LALUCA Research Platform A Prospective Analysis of Lung Cancer Diagnosis and Management in Clinical Practice (LALUCA)

Lung Cancer

Austria
Hellenic Cooperative Oncology Group

Completed

Pathogenic Variants in Homologous Recombination Repair Genes in Patients With Epithelial Ovarian Cancer (PaVaClO)

Epithelial Ovarian Cancer
Reproductive & Genetic Hospital of CITIC-Xiangya

Terminated

A Study of Preimplantation Genetic Screening With Next Generation Sequencing Technology on Advanced Age Women

Infertility

China
Imperial College London Diabetes Centre

Unknown

Application of UCPCR as a Testing Tool for Identification of MODY Patients in the UAE

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Maturity-onset Diabetes of the Young

United Arab Emirates
Karolinska University Hospital

Completed

NGS and TME for Evidence-based Treatment of Pancreatic Cancer (PePaCaKa-01)

Pancreatic Ductal Adenocarcinoma
Chinese Anti-Cancer Association

Unknown

The Registration Program of BRCA1/2 Gene (RCA)

Breast Cancer

China
Addario Lung Cancer Medical Institute
Dana-Farber Cancer Institute

Active, not recruiting

Study of Plasma NGS for Assessment, Characterization, Evaluation of Patients With ALK Resistance (SPACEWALK)

Non-Small Cell Lung Cancer

United States
Karius, Inc.
Tribhuvan University, Nepal

Completed

Detection of Dengue Virus in Plasma of Patients in Nepal

Dengue Fever

Nepal
Rothman Institute Orthopaedics

Unknown

NGS for Non-unions

Nonunion of Fracture

United States
Munich Leukemia Laboratory
Illumina, Inc.

Recruiting

Solving Riddles Through Sequencing (SIRIUS)

Leukemia | Rare Diseases | Refractory Lymphoma | Hematologic Malignancy | Refractory Leukemia | Unknown Primary Tumors

Germany
Imperial College London Diabetes Centre

Unknown

Delineation of Novel Monogenic Disorders in the United Arab Emirates Population

Mendelian Disorders | Genetic Disorder | Novel Mutation | Hereditary Disorder | De Novo Mutation | Inherited Disease | Single-Gene Defects

United Arab Emirates
Institut National de la Santé Et de la Recherche...
Institut Bergonié; Plateforme labellisée Inca - Institut Bergonié, Bordeaux; Plateforme... and other collaborators

Completed

Molecular Profiling to Improve Outcome of Patients in Cancer. A Pilot Study (MULTIPLI-0)

Soft Tissue Sarcoma | Colorectal Carcinoma

France
Regina Elena Cancer Institute
University of Rome Tor Vergata; Campus Bio-Medico University; Sant'Eugenio Hospital...

Recruiting

Transcriptomics and Epigenetics Analysis in Drug-Resistance of Multiple Myeloma (TEDROMM)

Multiple Myeloma

Italy
University Hospital, Essen

Completed

EGFRdelEx19 and KRAS Exon 2 Mutation Detection in EBUS-TBNA (EGFRdelEx19)

Lung Adenocarcinoma Metastatic
Groupe Français de Pneumo-Cancérologie
Takeda

Recruiting

Analysis of Biological Characteristics of Advanced ALK-rearranged NSCLC (BIOEXALK)

Non-small Cell Lung Cancer | ALK Gene Rearrangement Positive

France
Second Xiangya Hospital of Central South University
Geneplus-Beijing Co. Ltd.

Not yet recruiting

ctDNA-MRD in Stage IIIB-C NSCLC Patients Treated With Induction Chemoimmunotherapy

Non-small Cell Lung Cancer

China

Search clinical trials for: Next-Generation Sequencing (NGS)

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