Search clinical trials for: Nicotine pharmacokinetics

Total 12482 results

University Hospital Schleswig-Holstein

Recruiting

Evaluation of Safety and Pharmacokinetics of Oral Controlled-ileal-release Nicotinic Acid (CIR-NA) Compared to Immediate-release Nicotinic Acid and Placebo in Healthy Subjects and Subjects With Prediabetes

Safety Issues | Pharmacokinetic

Germany
Imperial Brands PLC

Recruiting

Nicotine Pharmacokinetic Study of Heated Tobacco and Heated Herbal Products

Healthy Volunteers

United Kingdom
University of California, San Francisco
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine

Nicotine Dependence | Nicotine Vaping

United States
Haukeland University Hospital

Recruiting

NAD-brain: a Pharmacokinetic Study of NAD Replenishment Therapy (NAD-brain)

Healthy

Norway
University of California, San Francisco
National Institute on Drug Abuse (NIDA)

Recruiting

Pharmacokinetics and Pharmacodynamics of Nicotine With Use of Standardized Research Electronic Cigarette (SREC) (SREC22)

Nicotine Dependence | Cardiovascular Risk Factors | Tobacco Toxicity

United States
H. Lee Moffitt Cancer Center and Research Institute
James and Esther King Biomedical Research Program

Recruiting

Enhancing Long-Term Smoking Abstinence Among Cervical Cancer Survivors (Project ACCESS)

Smoking Cessation | Cervical Cancer | High Grade Cervical Dysplasia

United States
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Recruiting

MRI and Biological Markers of Acute E-Cigarette Exposure in Smokers and Vapers (AeCE)

Serum Biomarkers | Vascular Reactivity

United States
Sir Mortimer B. Davis - Jewish General Hospital

Recruiting

Aggressive Smoking Cessation Trial (ASAP) (ASAP)

Acute Coronary Syndrome

Canada
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Recruiting

Pharmacokinetics, Subjective Effects, and Abuse Liability of Nicotine Salt-Based Vaping Products With Tobacco or Unflavored E-liquids, SALTVAPE Study

Nicotine Dependence

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Cancer Prevention Research Institute of Texas

Recruiting

Centralized Lung Cancer EARly Detection Among Smokers (CLEAR Study)

Smoking | Lung Cancer

United States
Milton S. Hershey Medical Center
National Institute on Drug Abuse (NIDA)

Recruiting

Low Nicotine Cigarettes Plus Electronic Cigarettes

Tobacco Dependence

United States
Philip Morris Products S.A.

Completed

Nicotine Pharmacokinetics Following Use of the P4M3 Gen 2.0 E-Cigarette Compared to Smoking Cigarettes

Nicotine | Nicotine Vaping | Vaping

United States
Centre Hospitalier Universitaire Dijon

Completed

Effectiveness of Transcranial Magnetic Stimulation (TMS) in Smoking Cessation, Combining Withdrawal Stimulation Followed by Maintenance Stimulation to Prevent Relapse. (TabacStim2)

Smoking Cessation

France
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Reduced Nicotine Cigarette Purchasing Decisions

Tobacco Use Disorder

United States
Roswell Park Cancer Institute

Terminated

Episodic Future Thinking and Future Thinking Priming for Smoking Cessation

Tobacco-Related Carcinoma

United States
Medical University of South Carolina

Completed

Tobacco Treatment in the Context of Lung Cancer Screening

Smoking Cessation

United States
Philip Morris Products S.A.

Active, not recruiting

Pharmacokinetics and Comparative Bioavailability of Nicotine From Two Variants of NP2, NP2-4mg and NP2-6mg, Compared to Nicotine Lozenge 4mg (Loz-4mg) and Nicotine Gum 4mg (Gum-4mg)

Tobacco Use

Canada
Washington State University
National Center for Complementary and Integrative Health (NCCIH); Office of...

Active, not recruiting

Evaluating the Pharmacokinetics and Drug Interaction Potential of the Botanical Dietary Supplement Cinnamon

Interaction Drug Food

United States
Mayo Clinic
Oregon Research Institute

Completed

A Pilot Study Evaluating Nicotine Lozenges and Self Help

Smokeless Tobacco Use

United States
Duke University
National Institutes of Health (NIH)

Completed

Learn to Quit-HIV Pilot Study

Smoking Cessation | HIV/AIDS | Tobacco Use Disorder

United States
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore
University of California, San Francisco
National Institute on Drug Abuse (NIDA)

Completed

Evaluating the Comparative Pharmacokinetics of Nicotine After Administration Via JUUL or Tobacco Cigarettes

Tobacco Smoking | Vaping | Nicotine Administration & Dosage | E-cigarettes | E-Liquid

United States
Philip Morris Products S.A.

Completed

Nicotine Pharmacokinetics of THS Single Use of a Regular or a Menthol Stick Compared to CIG

Smoking, Tobacco

United Kingdom
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
Oyster Point Pharma, Inc.

Completed

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of OC-01 in Adult Chinese With Dry Eye Disease

Dry Eye Disease

China
Seneque SA
Dicentra Inc.; LGD

Completed

Safety and Pharmacokinetics of Nicotinamide Mononucleotide (NMN) in Healthy Adults.

Healthy Volunteers

Canada
British American Tobacco (Investments) Limited
Philip Morris Products S.A.; Imperial Brands PLC; Japan Tobacco Inc.; Korea Ginseng...

Completed

A Nicotine Pharmacokinetics and Smoking Behaviour Study Examining Cigarette Ingredients

Smoking | Healthy Volunteers

United Kingdom
British American Tobacco (Investments) Limited

Completed

A Study to Characterize Nicotine Pharmacokinetics and Subjective Effects of Nicotine Pouches in Adult Cigarette Smokers

Tobacco Use | Tobacco Smoking

United States
University Hospital Schleswig-Holstein

Completed

Safety and Pharmacokinetics of Oral Controlled-ileocolonic-release Nicotinamide (CICR-NAM)

Safety Issues | Pharmacokinetic

Germany
University Hospital Inselspital, Berne
University of Bern

Completed

Pharmacokinetics and Pharmacodynamics of Different Nicotine Salt Concentration Vape System Pods and Free-base Nicotine

Nicotine Dependence

Switzerland
Philip Morris Products S.A.

Completed

Nicotine Pharmacokinetics and Subjective Effects of Nicotine Pouch 1.0 Compared to Velo® Ice Cool and Zyn® Cool Mint Mini Dry in Healthy Smokers

Smoking | Nicotine

United Kingdom
Cheerain HK Limited

Completed

Use Behavior, Nicotine Uptake, and Subjective Effects Comparison of Tobacco and Menthol e-Liquids by ENDS Consumers

Electronic Cigarette Use

United States
Juul Labs, Inc.

Completed

Comparing the Pharmacokinetics of Nicotine Salt Based ENDS in Healthy Smokers

Tobacco Use | Tobacco Smoking | Nicotine Dependence | Nicotine Dependence, Cigarettes

New Zealand
Juul Labs, Inc.

Completed

United States Pre-Market Tobacco Application Pharmacokinetics (US-PMTA-PK)

Tobacco Use | Tobacco Smoking | Nicotine Dependence | Nicotine Dependence, Cigarettes

United States
British American Tobacco (Investments) Limited

Completed

A Study to Assess the Pharmacokinetics of Oral Nicotine Pouches and Lozenges in Healthy Adults

Tobacco Use | Tobacco Smoking | Cigarette Smoking

United States
Cheerain HK Limited

Completed

Nicotine Uptake, Measures of Abuse Liability, and Puffing Topography With Use of RELX ENDS Products by Smokers

Electronic Cigarette Use

United States
Cheerain HK Limited

Completed

Nicotine Uptake, Measures of Abuse Liability, and Puffing Topography With Use of RELX ENDS Products by ENDS Consumers

Electronic Cigarette Use

United States
Philip Morris Products S.A.

Completed

Product Use and Adaptation, Safety and Tolerability of P3P in Adult Healthy Smokers Switching to it

Pharmacokinetics

Russian Federation
Columbia University
Merck Sharp & Dohme LLC

Completed

Phase I Vorinostat in Combination With Niacinamide and Etoposide for Lymphoid Malignancies (SAHA)

Non-Hodgkin's Lymphoma | Hodgkin's Disease

United States
CTC Bio, Inc.

Completed

A Clinical Trial to Compare Pharmacokinetics of the "CDFF0318" and "Champix Tab. 1mg"

Smoking Cessation | Pharmacokinetics

Korea, Republic of
Philip Morris Products S.A.

Completed

Nicotine Pharmacokinetics and Pharmacodynamics, Safety and Tolerability of P3P

Pharmacokinetics

Switzerland
Yuhan Corporation
Chonbuk National University Hospital

Completed

Clinical Trial to Evaluate the Safety and Pharmacokinetics of YHP1903 in Healthy Volunteers

Healthy Volunteer

Korea, Republic of
Philip Morris Products S.A.

Completed

Exploratory THS 2.1 Nicotine Pharmacokinetics and Safety Study

Smoking

United Kingdom
Korea University Anam Hospital

Completed

A Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of HIP1502

Healthy

Korea, Republic of
Milton S. Hershey Medical Center

Completed

Pharmacokinetics of Nicotine Film in Smokers

Smoking Cessation

United States
R.J. Reynolds Vapor Company
Celerion; RAI Services Company

Completed

Comparison of Nicotine Plasma Concentrations and Subjective Effects for Three Menthol Electronic Cigarettes vs Combustible Menthol Cigarettes and Nicotine Gum

Smoking

United States
R.J. Reynolds Vapor Company
Celerion; RAI Services Company

Completed

Comparison of Nicotine Plasma Concentrations and Subjective Effects for Three Electronic Cigarettes vs Combustible Cigarettes and Nicotine Gum

Smoking

United States
R.J. Reynolds Vapor Company
RAI Services Company; Davita Clinical Research

Completed

Assess Biomarkers of Tobacco Exposure and Nicotine Pharmacokinetics in Smokers After a 5-Day In-Clinic Confinement Switch to an Electronic Cigarette or Nicotine Gum

Smoking

United States
NJOY, Inc.
National Institute on Drug Abuse (NIDA); LA Clinical Trials

Completed

Nicotine Pharmacokinetics From Research Electronic Nicotine Delivery System S-TA-U001 in Smokers and E-Cigarette Users

Cigarette Smoking

United States
Janssen Pharmaceutical K.K.

Completed

A Study to Assess the Nicotine Pharmacokinetics, Tolerability and Safety With a New Oral Nicotine Replacement Product in Healthy Japanese Smokers

Healthy

Japan
Friends Research Institute, Inc.
Rose Research Center, LLC

Completed

Pharmacokinetics of Nicotine Sublingual Tablets Versus Nicorette Lozenge in Healthy Smokers

Tobacco Use Disorder | Cigarette Smoking

United States

Search clinical trials for: Nicotine pharmacokinetics

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