Search clinical trials for: Optimal trough drug concentration

Total 261359 results

Boston Medical Center
American Society of Health-System Pharmacists

Recruiting

Proactive Therapeutic Drug Monitoring Based Adalimumab Therapy Optimization in Patients With Rheumatoid Arthritis (TDM-RA)

Rheumatoid Arthritis

United States
University Hospital, Basel, Switzerland

Completed

Probability of Optimal Target Attainment of Amikacin in Patients With Febrile Neutropenia During Treatment for a Hematological Disorder

Febrile Neutropenia (FN)

Switzerland
Kyungpook National University Chilgok Hospital

Recruiting

Optimal Concentration of Remifentanil for NIM Tube Intubation With Low-dose NMBA

Thyroidectomy

Korea, Republic of
Tri-Service General Hospital

Not yet recruiting

Optimal Dosage of Remifentanil for Vertebroplasty

Analgesia | Remifentanil
The First Affiliated Hospital of Soochow University
Shandong Provincial Hospital; Qingdao Municipal Hospital; Central South University and other collaborators

Not yet recruiting

Optimal Adalimumab Plasma Concentrations in Ankylosing Spondylitis Patients

Ankylosing Spondylitis

China
Oncotelic Inc.

Not yet recruiting

A Study to Evaluate the Safety and Efficacy of OT-101+Artemisinin in Hospitalized COVID-19 Subjects

COVID-19

Brazil
Reade Rheumatology Research Institute
ZonMw: The Netherlands Organisation for Health Research and Development; Sint...

Recruiting

Adalimumab Drug Optimisation in Rheumatoid Arthritis Using Therapeutic Drug Monitoring (ADDORA)

Rheumatoid Arthritis

Netherlands
University of Geneva, Switzerland
University Hospital, Geneva

Recruiting

The OPTIMAL TDM Study: Determining Optimal Beta-lactam Plasma Concentrations Through Therapeutic Drug Monitoring (OPTIMAL TDM)

Efficacy | Toxicity | Beta-lactam Antibiotics | Therapeutic Drug Monitoring | Ceftazidime | Amoxicillin | Meropenem | Imipenem | Piperacillin | Flucloxacillin | Cefepime

Switzerland
Rennes University Hospital

Recruiting

Observational Study Comparing the Efficacy of Ganciclovir as a Function of Blood Exposure to the Drug During a Curative or Preemptive Treatment (GANEX)

Solid Organ Transplantation

France
Dezhou Hospital Qilu Hospital of Shandong University

Completed

Effectiveness of Botulinum Toxin A in Preventing Scar Formation and Initial Exploration of "Optimal Concentration"

Scar

China
Alimentiv Inc.

Active, not recruiting

Pharmacokinetics of IFX and TNF Concentrations in Serum, Stool, and Colonic Mucosa in Acute Severe Ulcerative Colitis (PROTOS)

Ulcerative Colitis

United States, Canada
Qilu Hospital of Shandong University

Active, not recruiting

Effectiveness of Botulinum Toxin A in Preventing Scar Formation and Initial Exploration of "Optimal Concentration"

Scar

China
St. Boniface Hospital
Agriculture and Agri-Food Canada

Active, not recruiting

Flax Muffins and Cholesterol Lowering

Above Optimal Plasma LDL Concentrations

Canada
Reade Rheumatology Research Institute
ZonMw: The Netherlands Organisation for Health Research and Development; Sint...

Active, not recruiting

Using Adalimumab Serum Concentration to Choose a Subsequent Biological DMARD in Rheumatoid Arthritis Patients Failing Adalimumab Treatment (ADDORA-switch)

Rheumatoid Arthritis

Netherlands
University Hospital, Ghent
KU Leuven

Completed

A Non-inferiority Study on Dose Reduction of Adalimumab in Psoriasis Patients Who Are Overtreated

Psoriasis

Belgium
Peking University Third Hospital

Completed

Vancomycin Dosage Strategy Based on a Trough Concentration Model

Pneumonia, Staphylococcal

China
University Hospital, Basel, Switzerland

Completed

Characterization of Adalimumab Concentrations in Pediatric Patients With Inflammatory Rheumatic Disease With and Without Methotrexate (ADA in PiRD)

Rheumatic Diseases

Switzerland, Germany
Novartis Pharmaceuticals

Terminated

Study of Nilotinib in Ph+ CML-CP Patients With Low Imatinib Trough Plasma Concentrations (MACS1148)

CML | Philadelphia Chromosome Positive (Ph+) | Chronic Myelogenous Leukemia Chronic Phase(CML-CP) Patients With Low Imatinib Trough Levels

United States
Kyungpook National University Hospital

Completed

Anti CT-P13 Antibody in Moderate to Severe Inflammatory Bowel Disease (OACIS)

Crohn's Disease | Ulcerative Colitis | Inflammatory Bowel Disease

Korea, Republic of
David Drobne

Unknown

Comparison of Two Different Golimumab Dosing Regimens for Ulcerative Colitis

Ulcerative Colitis

Slovenia
Sheba Medical Center

Completed

Effect of Vitamin D on Everolimus Trough Concentrations Among Heart Transplanted Patients

Vitamin D Deficiency

Israel
Severance Hospital
Armed Forces Capital Hospital, Republic of Korea

Completed

Optimal Sevoflurane Concentration for Intubation in Combination of Clincal Remifentanil Doses

Postoperative Pain

Korea, Republic of
Pinyo Rattanaumpawan

Unknown

Vancomycin Dosage Adjustment for MRSA Infections

Methicillin-Resistant Staphylococcus Aureus

Thailand
People's Hospital of Zhengzhou University

Completed

Loading Regimen，Serum Trough Concentrations，Efficacy and Safety in Pneumonia Patients With Gram-positive Infections

Pneumonia Gram-Positive Bacterial
University of Cagliari

Unknown

Optimal Remifentanil Concentration and Thyroidectomy (ORCO)

Anesthesia

Italy
Oslo University Hospital

Completed

Anti-TNF-alpha Trough Level Measurements in Inflammatory Bowel Disease

Crohn's Disease | Ulcerative Colitis | Inflammatory Bowel Disease

Norway
Universitaire Ziekenhuizen KU Leuven

Unknown

Adalimumab Trough Concentrations in Crohn's Disease: A Pilot Pharmacokinetic Study

Crohn's Disease

Belgium
University of Malaya
Malaysian Society of Anaesthesiologists

Completed

Optimal End-Tidal (ET) Sevoflurane and Desflurane Concentration for Extubation of Supreme Laryngeal Mask Airway (LMA) in Adults

Airway Complications

Malaysia
University of Zurich
Stanford University

Terminated

Study for Identifying Optimal Simvastatin Formulation for Uniform Time to Maximum Plasma Concentration

Celiac Disease

Switzerland
National Taiwan University Hospital

Completed

The Most Appropriate Parameter Correlates With Clinical Effectiveness of Vancomycin: Trough Drug Concentration or Area Under Curve (AUC)/Minimum Inhibitory Concentration (MIC)?

Methicillin-resistant Staphylococcus Aureus Septicemia

Taiwan
Sangjin Park

Completed

Optimal Effect-site Concentration of Remifentanil for Inhibiting Response to Laryngeal Mask Airway (LMA) Removal

Respiratory Complication
Bristol-Myers Squibb

Completed

Study to Assess Steady-State Trough Concentrations, Safety, and Immunogenicity of Abatacept After Subcutaneous (SC) Administration to Subjects With Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

United States
dingshifang
Shandong Provincial Hospital; Qianfoshan Hospital; Jinan Military General Hospital and other collaborators

Unknown

CYP 2C19 Polymorphism and Voriconazole Trough Concentration in Chinese Adult Patients

Invasive Pulmonary Aspergillosis

China
Hopital Lariboisière

Completed

Antiretroviral Therapy and Extreme Weight (EXTATIC)

HIV Infection

France
Chulalongkorn University

Completed

Concentration-controlled Therapy of Mycophenolate Mofetil (MMF) in Proliferative Lupus Nephritis

Lupus Nephritis

Thailand
Yonsei University

Completed

The Optimal Effect Site Concentration of Propofol for Conscious Sedation in Elderly Male Patients Undergoing Urologic Surgery Under Spinal Anesthesia With or Without Intrathecal Fentanyl

Conscious Sedation Under Spinal Anesthesia

Korea, Republic of
Sheppard Pratt Health System
Stanley Medical Research Institute

Completed

Artemisinin to Reduce The Symptoms of Schizophrenia

Schizophrenia | Schizoaffective Disorder

United States
The Canberra Hospital

Unknown

Dose Enhancement of Vancomycin IN Everyday Patients (DEVINE)

Vancomycin Therapy

Australia
Mayo Clinic
Medtronic

Completed

Optimal Heparin Dosing Regimens for Cardiopulmonary Bypass (Heparin Dosing)

Postoperative Hemorrhage

United States
Innovative Medical

Completed

Aqueous Concentrations and PGE2 Inhibition of Ketorolac 0.4% vs. Bromfenac 0.09% in Cataract Patients: Trough Drug Effects

Cataract

United States
Fresenius Medical Care Deutschland GmbH
Winicker Norimed GmbH

Not yet recruiting

Influence of Variable Inflow Volume, Dwell Duration and Glucose Concentration on Ultrafiltration Volume in APD Patients (pPD)

Chronic Kidney Diseases | Renal Failure
Novartis Pharmaceuticals

Not yet recruiting

Concentration of Ofatumumab in the Breast Milk of Lactating Women With Relapsing Forms of Multiple Sclerosis (KATHAROS)

Multiple Sclerosis
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Efficacy and Safety of Bezafibrate 400 mg and Bezafibrate 200 mg as Adjunctive Treatments in Patients With Primary Biliary Cholangitis and Non-optimal Biochemical Response to Ursodeoxycholic Acid Therapy (BEZURSO 2)

BPC | Non Optimal Response to UDCA

France
West China Hospital

Recruiting

Use of Bleomycin in the Sclerotherapy of Lymphatic Malformations for Pediatric Patients

Lymphatic Malformation

China
Postgraduate Institute of Dental Sciences Rohtak

Recruiting

Outcome Following Use of Different Concentrations of NaOCl as Wound Lavage and Hemostatic Agent in Partial Pulpotomy

Irreversible Pulpitis | Extremely Deep Caries | Partial Pulpotomy

India
First Affiliated Hospital, Sun Yat-Sen University

Not yet recruiting

The Correlation Between Ripretinib Exposure and the Efficacy and Safety in Patients With Advanced GISTs

Gastrointestinal Stromal Tumors
University of Sao Paulo

Not yet recruiting

Interventions to Control Hypersensitivity Pain in Teeth With Insisive Molar Hypomineralization (LBIARHMI)

Molar Incisor Hypomineralization
Bronx VA Medical Center

Not yet recruiting

Dose Optimization of MDMA-Assisted Therapy for PTSD (DosOp)

Posttraumatic Stress Disorder
Istanbul University - Cerrahpasa (IUC)

Not yet recruiting

Attentional Focus in Virtual Reality

Attentional Focus in Virtual Reality
Mayo Clinic
Universidade Federal de Goias; University of Wisconsin, Eau Claire

Recruiting

A Study of Melatonin Concentration During Lactation

Breastfeeding

United States

Search clinical trials for: Optimal trough drug concentration

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