Search clinical trials for: Oral Proteolytic and Hydrolytic Enzymes

Total 470894 results

St Stephens Aids Trust
Bristol-Myers Squibb

Terminated

Pharmacokinetic Effect of Evotaz/Microgynon Co-administration

HIV

United Kingdom
Postgraduate Institute of Medical Education and...
Cipla Ltd.

Completed

Voriconazole Versus Oral Steroids in Allergic Bronchopulmonary Aspergillosis

Allergic Bronchopulmonary Aspergillosis

India
Alcon Research

Terminated

Proof-of-Concept Study of a Single Application of an Investigational Otic Suspension in Treatment of Acute Otitis Media With Tympanostomy Tubes

Acute Otitis Media
Babylon University
Ministry of Health, Iraq

Completed

Effect of Oral Zinc Sulfate Supplementation on Enzymes of Urate Pathway

Infertility Unexplained

Iraq
Lisa Sanderson Cox, PhD
National Cancer Institute (NCI)

Completed

Health Education Counseling With or Without Bupropion in Helping African Americans Stop Smoking

Kidney Cancer | Cervical Cancer | Leukemia | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Tobacco Use Disorder | Lung Cancer | Bladder Cancer | Liver Cancer

United States
Merck Sharp & Dohme LLC

Completed

Pharmacokinetics, Safety, and Tolerability of Intravenous Posaconazole Solution Followed by Oral Posaconazole Suspension in Subjects at High Risk for Invasive Fungal Infections (P05520)

Fungal Infection
Millennium Pharmaceuticals, Inc.

Completed

Pharmacokinetics Study of Oral IXAZOMIB in Participants With Advanced Nonhematologic Malignancies or Lymphoma

Lymphoma | Nonhematologic Malignancies

United States
Seoul National University Hospital

Completed

Influence of SLCO2B1 Polymorphism on the PK of Voriconazole in CYP2C19 PM

Healthy Volunteers

Korea, Republic of
Assiut University

Unknown

Effect Of DAAs For Treatment Of HCV On Normal Kidney

Antiviral Drug Adverse Reaction
Par Pharmaceutical, Inc.
Novum Pharmaceutical Research Services

Terminated

Bioequivalence of Two Ciprofloxacin 0.3%/Dexamethasone 0.1% Sterile Otic Suspensions in Otitis Media in Children With Tympanostomy Tubes

Otitis Media in Patients With Tympanostomy Tubes

United States
Pfizer
Forest Laboratories

Completed

Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)

Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis

Croatia, Brazil, Bulgaria, Korea, Republic of, Russian Federation, Hungary, Poland, Romania, Ukraine, Argentina, Israel, Portugal, Greece, Taiwan, Japan, Slovakia, Serbia, United States, Mexico, Germany, Turkey, Czechia
Pfizer
Forest Laboratories

Completed

Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)

Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis

Croatia, Bulgaria, Korea, Republic of, Mexico, Peru, Poland, Russian Federation, Spain, Romania, Ukraine, United States, Argentina, Czechia, Israel, Taiwan, Germany, Italy
Laboratorios Silanes S.A. de C.V.
INTEC Instituto de Terapéutica Experimental y Clínica, Departamento de Fisiología... and other collaborators

Suspended

Fixed Dose Combination of Fluoxetin and Metformin in the Management of Overweight and Obesity (Metfluo)

Overweight and Obesity

Mexico
AdventHealth
Sagent Pharmaceuticals Inc.

Completed

Intra-Venous Acetaminophen and Muscle Relaxants After Total Knee (IVAM)

Unilateral Knee Arthroplasty

United States
GlaxoSmithKline

Completed

Effect of Omeprazole and Ritonavir on GSK2336805 Pharmacokinetics in Healthy Adults

Hepatitis C

United States
Fundación Cardioinfantil Instituto de Cardiología
Instituto de Corazón de Bucaramanga

Unknown

A Trial Testing Amiodarone in Chagas Cardiomiopathy (ATTACH)

Chagas Cardiomyopathy

Colombia
MerLion Pharmaceuticals GmbH

Completed

Finafloxacin for the Treatment of cUTI and/or Acute Pyelonephritis

Urinary Tract Infections | Acute Pyelonephritis

Germany
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Oral Doses of JNJ-54175446 on the Inhibition of Cytochrome P450 CYP3A4, CYP2C9, CYP1A2 and CYP2D6 Activity and the Induction of CYP2B6 and CYP2C19 Activity Using a Multiple Probe Substrate Cocktail in Healthy Subjects

Healthy

Belgium
Mansoura University

Unknown

Conventional Antibiotic Prophylaxis Versus Add-On 5 Days Levofloxacin Before Percutaneous Nephrolithotomy

Sepsis | Infection | Antibiotics | Percutaneous Nephrolithotomy

Egypt
Roswell Park Cancer Institute

Completed

Bupropion in Helping Adults Stop Smoking

Kidney Cancer | Cervical Cancer | Leukemia | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Tobacco Use Disorder | Lung Cancer | Bladder Cancer | Liver Cancer

United States
GlaxoSmithKline

Completed

Levofloxacin For The Management Of Patients With Abnormal Prostate Specific Antigen (PSA)

Prostatic Hyperplasia | Prostatitis

Italy
Bulent Ecevit University

Completed

The Effects of a Synbiotic Addition on Eradication Therapy of Helicobacter Pylori Infection in Children

Helicobacter Pylori Infection
F2G Biotech GmbH
SimbecRresearch Ltd.

Completed

Multiple Ascending Oral Dose Study of F901318 in Healthy Subjects (ORALMAD)

Invasive Aspergillosis

United Kingdom
Centre Hospitalier Universitaire, Amiens

Withdrawn

Evaluation of the Pharmacokinetic Profile, Pharmacodynamic Effects, Acceptability and Tolerability of an Oral Amiodarone Solution of 15 mg / mL in Children With Supra Ventricular Tachycardia (Enteramio)

Supraventricular Tachycardia

France
University of North Carolina, Chapel Hill
University of Colorado, Denver; Baylor College of Medicine; Washington University... and other collaborators

Terminated

Early Methicillin-resistant Staphylococcus Aureus (MRSA) Therapy in Cystic Fibrosis (CF) (STAR-Too)

Cystic Fibrosis | Methicillin-resistant Staphylococcus Aureus

United States
University of Aarhus
Aarhus University Hospital

Terminated

Concentrations of Voriconazole in Blood and BAL-fluid After Inhalation and Oral Administration

Invasive Aspergillosis

Denmark
Dr. R. Pfleger Chemische Fabrik GmbH

Completed

Pharmacokinetic Interaction Between Trospium With an Inhibitor of OCT1 and of P-gp in Subjects Genotyped for OCT1

Pharmacokinetics | Drug Interaction Potentiation | Inhibition Enzyme
Merck Sharp & Dohme LLC

Completed

Oral Posaconazole in High Risk Patients With Gastrointestinal Dysfunction (Study P05115)

Fungal Infection | Neutropenia | Acute Myelogenous Leukemia
University of Illinois College of Medicine at Peoria

Unknown

Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery

Pain, Postoperative | Constipation | Colon Cancer | Colonic Neoplasms | Ileus | Rectum Cancer | Constipation Drug Induced | Rectum Neoplasm | Colonic Diverticulitis | Ileus Paralytic | Colon Diverticulosis | Ileus; Mechanical

United States
Pfizer

Completed

Intravenous Azithromycin Plus Intravenous Ceftriaxone Followed by Oral Azithromycin With Intravenous Levofloxacin Followed by Oral Levofloxacin for the Treatment of Moderate to Severely Ill Hospitalized Patients With Community Acquired Pneumonia

Community-Acquired Pneumonia (CAP)

United States, Canada, Germany, Greece, Spain
Merck Sharp & Dohme LLC

Completed

Prophylaxis Trial in High Risk Allogenic Stem Cell Transplant Recipients With Graft vs. Host Disease

Mycoses
Merck Sharp & Dohme LLC

Completed

Prophylaxis Trial of Posaconazole Versus Standard Azole Therapy for Neutropenic Patients (Study P01899)

Myelodysplastic Syndromes | Neutropenia | Leukemia, Myelocytic, Acute
Merck Sharp & Dohme LLC

Completed

Study of Posaconazole in the Treatment of Invasive Fungal Infections (Study P02095)

Mycoses
Melinta Therapeutics, Inc.

Completed

Efficacy and Safety Study of Oral CEM-101 Compared to Oral Levofloxacin in Treatment of Patients With Community-Acquired Bacterial Pneumonia

Community-Acquired Bacterial Pneumonia

United States, Canada
The Netherlands Cancer Institute

Unknown

Oral Docetaxel (ModraDoc/r) in Combination With Hormonal Treatment and Radiation Therapy in High-risk Prostate Cancer (DOP)

Prostatic Neoplasms

Netherlands
Janssen Research & Development, LLC

Completed

Pharmacokinetic Study of Intranasal Esketamine and Its Effects on the Pharmacokinetics of Orally-Administered Midazolam and Bupropion in Healthy Participants

Healthy

Belgium
Cairo University

Unknown

Combined Oral Contraceptives and Fluoxetine Versus Combined Oral Contraceptives in Severe Premenstrual Syndrome

Premenstrual Syndrome

Egypt
GlaxoSmithKline

Terminated

Evaluation of the Safety, Tolerability and Pharmacokinetics of Repeat Oral Doses of GSK580416

Infections, Bacterial | Bacterial Infection

Australia
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Evaluate the Effect of Food on Levofloxacin Pharmacokinetics From an Oral Solution Formulation

Healthy
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Evaluate the Bioequivalence of an Oral Suspension Formulation, an Oral Solution Formulation, and the Marketed Tablet Formulation of Levofloxacin in Healthy Subjects

Healthy
University of Miami

Completed

Fluconazole in Preventing Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer

Head and Neck Cancer | Infection | Oral Complications

United States
Hoffmann-La Roche

Completed

A Study to Evaluate The Effects of Two Different Meal Types, Omeprazole And Ranitidine On Danoprevir Pharmacokinetics When Coadministered With Ritonavir in Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study of Danoprevir in Combination With Low-Dose Ritonavir in Healthy Subjects

Healthy Volunteer

France
AstraZeneca

Completed

To Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of Olaparib, and the Effect of Olaparib on QT Interval Following Oral Dosing of a Tablet Formulation to Patients With Advanced Solid Tumours

Solid Tumours

Belgium, Denmark, United Kingdom, Netherlands
M.D. Anderson Cancer Center
Enzon Pharmaceuticals, Inc.

Completed

Oral Posaconazole Three Times Per Day vs Weekly High Dose Amphotericin B Lipid Complex (ABLC)

Invasive Fungal Infections | Hematologic Malignancies

United States
ANRS, Emerging Infectious Diseases
Institut Pasteur; Hôpital Necker-Enfants Malades; Hospital Avicenne; CHU Kamenge... and other collaborators

Unknown

Study Evaluating Efficiency and Tolerance of High-dose Fluconazole Associated With Flucytosine as Induction Therapy for Cryptococcal Meningitis Associated With HIV in Sub-saharan Africa (Flucocrypto)

HIV | Cryptococcal Meningitis

Burundi, Côte D'Ivoire
Cairo University

Unknown

Does Adding Oral Contraceptives to Fluoxetine Improve the Management of Premenstrual Syndrome?

Premenstrual Syndrome

Egypt
University of Sao Paulo
Financiadora de Estudos e Projetos

Completed

Efficacy of Standardized-propolis Extract (EPP-AF®) Gel Formulation as Buccal Antiseptic

Candidiasis, Oral | Stomatitis, Denture

Brazil
Astellas Pharma Global Development, Inc.
Yale University

Completed

A Positron Emission Tomography Occupancy Study Using Ligand [11C]AS2471907 and Following Oral Dosing of ASP3662

Healthy Volunteers | Pharmacokinetics of ASP3662 | Displacement of Radiotracer

United States
Hadassah Medical Organization

Completed

Bioequivalence Assessment of Oral Administration Vs. Oral Spray of a Cannabinoids (Tetrahydrocannabinol and Cannabidiol)

Pain

Israel

Search clinical trials for: Oral Proteolytic and Hydrolytic Enzymes

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