Search clinical trials for: Oral parasitic drug

Total 263044 results

International Centre for Diarrhoeal Disease Research...

Recruiting

Repurposing Ivermectin for PKDL Treatment

Post-kala-azar Dermal Leishmaniasis

Bangladesh
60 Degrees Pharmaceuticals LLC

Not yet recruiting

Oral Tafenoquine Plus Standard of Care Versus Placebo Plus Standard of Care for Babesiosis

Babesiosis
Jennifer Keiser
Public Health Laboratory Ivo de Carneri

Not yet recruiting

Efficacy and Safety of MOX/ALB Co-administration in SAC (Moxiped)

Hookworm Infections | Ascariasis | Trichuriasis

Tanzania
Jennifer Keiser
Public Health Laboratory Ivo de Carneri

Not yet recruiting

Efficacy, Safety and Acceptability of Ivermectin ODT in PSAC (Iverped)

Hookworm Infections | Ascariasis | Trichuriasis

Tanzania
Ifakara Health Institute
University of Oxford

Not yet recruiting

In-vivo Transmission Model in Semi-immune Adults

Controlled Human Malaria Infection | Malaria Transmission | Induced Blood Stage Malaria Infection | Malaria Challenge

Tanzania
University of Brasilia

Recruiting

Pilot Study: Oral Treatment of American Tegumentary Leishmaniasis (Cutaneous and Mucosal Forms) in the Elderly

Leishmaniasis, Mucocutaneous | Leishmaniasis; Brazilian

Brazil
Hospital Universitário Professor Edgard Santos
Instituto Gonçalo Muniz FIOCRUZ BA

Not yet recruiting

Tofacitinib Associated With Meglumine Antimoniate in Cutaneous Leishmaniasis (CLTofa23)

Cutaneous Leishmaniasis, American

Brazil
Zydus Lifesciences Limited

Not yet recruiting

A Study to Determine Safety, Tolerability, and Pharmacokinetics of Different Orally Administered Regimens of the Combination ZY19489-Ferroquine in Adult Asymptomatic Plasmodium Falciparum Carriers

Asymptomatic Condition | Falciparum Malaria | Uncomplicated Malaria
Medicines Development for Global Health

Recruiting

Efficacy and Safety Study of Moxidectin in Adults With Scabies

Scabies

United States, Honduras
King Faisal Hospital Rwanda

Not yet recruiting

Addressing Asymptomatic Plasmodium Reservoirs to Accelerate Malaria Elimination and Eradication in Rwanda.

Malaria,Falciparum
Duke University
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics (INTREPiD)

Pregnancy | Preterm Birth | Gestational Age and Weight Conditions | Malaria in Pregnancy | Stillbirth | Low Birthweight | Malaria,Falciparum | Neonatal Health | Malaria in Childbirth

Congo, The Democratic Republic of the, Kenya
Zagazig University

Recruiting

Intralesional Voriconazole, or Intralesional Cryotherapy, or Oral Doxycycline in the Treatment of Cutaneous Leishmaniasis

Leishmaniasis, Cutaneous

Libyan Arab Jamahiriya
Centre Hospitalier de Cayenne

Not yet recruiting

Study of Cases of Cutaneous Leishmaniasis Treated With Miltefosine in French Guiana, Retrospective Study (MILT2022)

Treatment Adherence | Primary Health Care | Cutaneous Leishmaniases | Drug Evaluation
Shangrong Fan

Not yet recruiting

Safety and Efficacy of Two Oral Tinidazole Regimens for Refractory Trichomonas Vaginitis

Trichomonas Vaginitis

China
University of Oxford
Malaria Research and Training Center, Bamako, Mali

Recruiting

Assessment of Safety and Immunogenicity of a Single Vial Presentation of R21/Matrix-M and Co-Administration With EPI Vaccines

Malaria

Mali, United Kingdom
University of Sao Paulo General Hospital
InCor Heart Institute

Recruiting

Angiotensin Receptor-Neprilysin Inhibition in Chagas Cardiomyopathy With Reduced Ejection Fraction: ANSWER-HF. (ANSWER-HF)

Chagas Cardiomyopathy

Brazil
University of Oxford
Kenya Medical Research Institute; Fundação Alfredo da Matta (FUAM); Fundação... and other collaborators

Recruiting

Ivermectin Safety in Small Children (ISSC)

Scabies

Brazil, Gambia, Kenya
Tulane University School of Public Health and Tropical...
University of California, San Diego; Institute for Clinical Effectiveness and...

Recruiting

Short-course Benznidazole Treatment to Reduce Trypanosoma Cruzi Parasitic Load in Women of Reproductive Age (BETTY)

Chagas Disease

United States, Argentina
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Enhancing Preventive Therapy of Malaria In Children With Sickle Cell Anemia in East Africa (EPiTOMISE) (EPiTOMISE)

Malaria,Falciparum

Kenya
Phramongkutklao College of Medicine and Hospital

Active, not recruiting

Comparison Effectiveness of Oral Ivermectin , 1% Permethrin Shampoo and 4% Dimeticone Liquid Gel in the Treatment of Pediculosis Capitis Among School Children in Chachoengsao Province, Thailand

Ivermectin | School-age Children | Pediculus Capitis Infestation | Permethrin Adverse Reaction | Dimethicone Adverse Reaction | Permethrin Allergy | Dimethicone Allergy

Thailand
University Hospital Tuebingen

Terminated

Safety and Drug Absorption of Orally Administered Oleylphosphocholine (OlPC) in Healthy Adults

Leishmaniasis

Germany
Jennifer Keiser
Centre Suisse de Recherches Scientifiques en Cote d'Ivoire

Completed

Efficacy and Safety of MOX/ALB Co-administration

Hookworm Infections | Ascariasis | Trichuriasis

Côte D'Ivoire
Medicines for Malaria Venture

Completed

Piperaquine Granule Formulation Relative Bioavailability and Food Effect Study in Healthy Volunteers. (PedPQP(BA/FE))

Malaria

Tanzania
Brian Foy
National Institute of Allergy and Infectious Diseases (NIAID); Radboud University... and other collaborators

Active, not recruiting

Repeat Ivermectin Mass Drug Administrations for MALaria Control II (RIMDAMAL II)

Malaria

Burkina Faso
Research Institute of Epidemiology, Microbiology...

Active, not recruiting

Anti-protozoal Effect of Steroid Hormone 20-hydroxyecdysone

Giardia Lamblia Infection

Uzbekistan
Medicines Development for Global Health

Completed

Dose-finding Study of Moxidectin for Treatment of Scabies

Scabies

Australia, Austria, France
Assistance Publique - Hôpitaux de Paris

Completed

Efficacy Study Between Two Different Dosages of an Antiparasitic in Patients With Crusted Scabies (GALECRUSTED)

Ivermectin | Gale | Severe Forms of Scabies | Oral Parasitic Drug

France
AbbVie
Drugs for Neglected Diseases initiative

Terminated

Study to Assess Adverse Events, Change in Disease Activity and How Oral ABBV-4083 Capsules When Given Alone or In Combination With Albendazole Capsules Moves in The Body of Adult Participants With Onchocerca Volvulus Infection

Onchocerciasis

Congo, The Democratic Republic of the
Barcelona Institute for Global Health
Medical University of Vienna; Centro de Investigação em Saúde de Manhiça; Centre... and other collaborators

Completed

Improving Maternal heAlth by Reducing Malaria in African HIV Women (MAMAH)

HIV/AIDS | Pregnancy Related | Malaria

Gabon, Mozambique
Drugs for Neglected Diseases

Completed

DDI Study of Single Oral Dose of Acoziborole With Sequential Co-administration of Midazolam and Dextromethorphan (OXA-07)

Trypanosomiasis, African

Malaysia
Center for Research on Filariasis and Other Tropical...

Active, not recruiting

Clinical Trial Evaluating the Safety and Efficacy of Moxidectin 2 mg Ivermectin-controlled in Loa Loa Microfilaremic Patients (EOLoa)

Onchocerciasis, Ocular | Loiasis

Cameroon
Radboud University Medical Center
The PATH Malaria Vaccine Initiative (MVI)

Terminated

Safety and Efficacy of NF135 CPS Immunization (CPS135)

Malaria,Falciparum | Controlled Human Malaria Infection | Immunization; Infection

Netherlands
Research Institute of Epidemiology, Microbiology...

Active, not recruiting

Role of Intestinal Protozoa and Helminths in the Course of Ulcerative Colitis

Protozoan Infections | Ulcerative Colitis | Ulcerative Colitis Exacerbation | Helminth Infection
First Affiliated Hospital of Zhejiang University

Completed

Synbiotics Interventions for Managing Cirrhosis and Its Complications

Cirrhosis, Liver | Metagonimiasis

China
Drugs for Neglected Diseases
Wellcome Trust grant 212346/Z/18/Z - 21st Century Treatments for Sustainable...

Completed

Single Oral Dose Escalation Study of DNDI-0690 in Healthy Subjects

Visceral Leishmaniasis | Cutaneous Leishmaniases

United Kingdom
Medicines Development for Global Health
World Health Organization

Completed

Study Evaluating Orally Administered Moxidectin In Subjects With Onchocerca Volvulus Infection

Onchocerciasis

Ghana
Combined Military Hospital Abbottabad

Completed

Comparison of Oral Ivermectin and Permethrin 5% Lotion in Treatment of Pediculosis Capitis

Pediculosis

Pakistan
Combined Military Hospital Abbottabad

Completed

Comparative Study Between Topical Permethrin 5% and Oral Ivermectin for the Treatment of Scabies

Scabies

Pakistan
Bandim Health Project

Completed

Effectiveness and Safety of Artemether + Lumefantrine and Dihydroartemisinin + Piperaquine for Treating Malaria

Malaria | Effectiveness

Guinea-Bissau
Jennifer Keiser
Public Health Laboratory Ivo de Carneri

Completed

Efficacy and Safety of MOX/ALB vs. IVM/ALB Co-administration

Hookworm Infections | Helminthes; Infestation, Intestinal | Ascariasis | Trichuriasis

Tanzania
B.P. Koirala Institute of Health Sciences

Completed

Better Disease Control by Multidrug Regimen in Scabies

Scabies
Medicines for Malaria Venture
Sanaria Inc.; Institute of Tropical Medicine, Belgium; Iqvia Pty Ltd; SGS Life... and other collaborators

Completed

Study in Blood Stage Malaria Infection After DVI of Cryopreserved P. Falciparum (NF54 Strain) Sporozoites

Protozoan Infections | Parasitemia | Malaria,Falciparum | Parasitic Disease

Belgium
Dr. Reddy's Laboratories Limited

Completed

Study to Evaluate the Effect of Ha44 Gel on the Electrocardiogram in Healthy Volunteers

Pediculosis

United States
Medicines for Malaria Venture
Washington University School of Medicine; Sanaria Inc.; Institute of Tropical... and other collaborators

Completed

Safety, Tolerability and Chemoprotective Activity of P218 in PfSPZ Challenge Model

Malaria

Belgium
Jennifer Keiser
National Centre for Parasitology, Entomology and Malaria Control, Cambodia; National Institute of Public Health, Vientiane, Laos

Enrolling by invitation

Efficacy, Safety, and PK of Ascending Dosages of Moxidectin Versus Ivermectin Against Strongyloides Stercoralis (StrongMoxi)

Strongyloides Stercoralis Infection

Cambodia, Lao People's Democratic Republic
Cairo University

Unknown

Parasitic Infection in Anemic Pregnant Women

Anemia of Pregnancy

Egypt
Fundacion Nacional de Dermatologia
Hospital Dermatologico de Jorochito; Ministerio de Salud de Bolivia, Programa... and other collaborators

Completed

Oral Miltefosine Plus Topical Paromomycin In American Cutaneous Leishmaniasis

Cutaneous Leishmaniasis, American

Bolivia
Drugs for Neglected Diseases

Completed

Oral Fexinidazole Dosing Regimens for the Treatment of Adults With Chronic Indeterminate Chagas Disease (FEXI12)

Chagas' Disease (Chronic) Nos

Spain
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; QIMR Berghofer...

Completed

Safety, Tolerability and Pharmacokinetic Profile of Ascending Oral Doses of MMV390048, Part A

Malaria

Australia
University of Minnesota
National Institute of Allergy and Infectious Diseases (NIAID); Mbarara University... and other collaborators

Terminated

Cryptococcal Antigen Screening Plus Sertraline (C-ASSERT)

Cryptococcosis | AIDS-Related Opportunistic Infections | Cryptococcal Infections

Uganda

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