Search clinical trials for: Organic Acidemia

Total 386 results

ModernaTX, Inc.

Recruiting

A Long-Term Extension Study to Evaluate the Safety and Clinical Activity of mRNA-3927

Propionic Acidemia

United States, Canada, United Kingdom
Children's National Research Institute
National Center for Advancing Translational Sciences (NCATS)

Recruiting

Systemic Biomarkers of Brain Injury From Hyperammonemia

Hypoxic-Ischemic Encephalopathy | Urea Cycle Disorder | Organic Acidemia | Fatty Acid Oxidation Disorder | Maple Syrup Urine Disease | Glutaric Acidemia I

United States
Recordati Rare Diseases

Recruiting

Understanding the Long-Term Management of Organic Acidemia Patients With CARBAGLU®: A Mixed Methods Approach (PROTECT)

Propionic Acidemia | Methylmalonic Acidemia

France, Spain, Italy, United Kingdom, Norway, Germany, Sweden
ModernaTX, Inc.

Recruiting

Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia

Propionic Acidemia

United States, Canada, United Kingdom
National Human Genome Research Institute (NHGRI)

Recruiting

Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic Acidemia

Propionic Acidemia | Metabolic Disease | Organic Acidemia

United States
National Human Genome Research Institute (NHGRI)

Recruiting

Clinical and Laboratory Study of Methylmalonic Acidemia

Inborn Errors of Metabolism | Methylmalonic Acidemia | Organic Acidemia

United States
National Human Genome Research Institute (NHGRI)

Completed

Maternal Inborn Errors of Metabolism in Pregnancy: A Pregnancy Registry Protocol

Pregnancy | Inborn Errors of Metabolism | Acidemias

United States
LogicBio Therapeutics, Inc
Alexion Pharmaceuticals, Inc.

Terminated

Gene Therapy With hLB-001 in Pediatric Patients With Severe Methylmalonic Acidemia (SUNRISE)

Methylmalonic Acidemia

United States
HemoShear Therapeutics

Terminated

Study of HST5040 in Subjects With Propionic or Methylmalonic Acidemia (HERO)

Propionic Acidemia | Methylmalonic Acidemia

United States, Saudi Arabia, Australia
HemoShear Therapeutics
Prometrika, LLC; AllStripes Research Inc.; Genome Medical

Terminated

Natural History Study of Patients With Methylmalonic Acidemia and Propionic Acidemia (JUMP)

Propionic Acidemia | Methylmalonic Acidemia

United States, Canada, United Kingdom
CoA Therapeutics, Inc., a BridgeBio company

Terminated

A First in Human, Dose Escalation Study to Evaluate the Safety and Tolerability of BBP-671 in Healthy Volunteers and Patients With Propionic Acidemia or Methylmalonic Acidemia

Healthy Volunteers | Propionic Acidemia | Methylmalonic Acidemia | Organic Acidemia

United States
Selecta Biosciences, Inc.
National Human Genome Research Institute (NHGRI)

Suspended

A Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SEL-302 in Pediatric Subjects With MMA (reiMMAgine)

Methylmalonic Acidemia (MMA)

United States
Target PharmaSolutions, Inc.
Recordati Rare Diseases

Enrolling by invitation

A Non-Interventional Post-Authorization Study of Carbaglu for the Treatment of Hyperammonemia Due to MMA and PA

Propionic Acidemia | Methylmalonic Acidemia | Hyperammonemia

United States
Hacettepe University

Completed

The Effect of the Cognitive Orientation to Daily Occupational Performance Approach for Children With Organic Acidemia

Organic Acidemia | Cognitive Orientation

Turkey
ModernaTX, Inc.

Completed

"The MaP Study": Mapping the Patient Journey in MMA and PA

Propionic Acidemia | Methylmalonic Acidemia

United States, United Kingdom, Spain, France
National Taiwan University Hospital

Unknown

Long-term Efficacy of Carglumic Acid in Organic Acidemia.

Propionic Acidemia (PA) , Methylmalonic Acidemia (MMA)

Taiwan
German Diabetes Center
University Children's Hospital, Düsseldorf

Completed

Energy Metabolism in Branched-chain Organic Acidemias

Metabolic Syndrome | Insulin Resistance | Energy Metabolism

Germany
Uta Lichter-Konecki
Medical College of Wisconsin; Children's National Research Institute

Completed

Pilot Study For Hypothermia Treatment In Hyperammonemic Encephalopathy In Neonates And Very Young Infants

Urea Cycle Disorders | Organic Acidemias

United States
Owlstone Ltd

Recruiting

Assessment of Volatile Organic Compounds (VOC) for the Diagnosis of Invasive Aspergillosis (IA) in Lung Transplant Recipients (UHN)

Invasive Aspergillosis

Canada
University Hospital, Antwerp

Not yet recruiting

The Role of VOCs, Airway Mucins and Airway Microbiome in Bronchopulmonary Dysplasia (INFANCY)

Bronchopulmonary Dysplasia
Michele Tinazzi, MD, PhD
Azienda Ospedaliera OO.RR. S. Giovanni di Dio e Ruggi D'Aragona; IRCCS Ospedale...

Recruiting

Study of Biomorkers and Rehabilitation Strategies in Functional Motor Disorders (FMD)

Functional Motor Disorders

Italy
Picomole Inc
Vitalite Health Network

Recruiting

Using Infrared Spectroscopy to Analyze Volatile Organic Compounds (VOCs) in the Breath of Patients With Lung Cancer

Lung Cancer | Non Small Cell Lung Cancer

Canada
Shanghai Vitalgen BioPharma Co., Ltd.

Recruiting

A Study to Evaluate the Tolerability, Safety and Efficacy of VGM-R02b

Glutaric Acidemia Type I | Glutaric Aciduria Type I

China
University of Rostock
Prof. Dr. Daniel A. Reuter, Head of Department, Department of Anesthesiology... and other collaborators

Recruiting

Prognostic Value of Exhaled Isoprene Levels for Morbidity and Functional Outcome in Cardiosurgical Patients (PREDICT)

Muscle Weakness | Frailty | Volatile Organic Compounds | Isoprene

Germany
Imperial College London
Imperial College Healthcare NHS Trust

Recruiting

Volatile Organic Compounds as Breath Biomarkers in Squamous Oesophageal Neoplasms (ViSON)

Oesophageal Squamous Cell Carcinoma | Oesophageal Cancer

United Kingdom
Bursa City Hospital

Not yet recruiting

Enteral Feeding of Premature Babies and Olive Oil Supplementation

Enteral Feeding | Premature | Olive Oil
Memorial Sloan Kettering Cancer Center
UNIVERSITY CAMPUS BIO-MEDICO, ITALY

Recruiting

Using E-Nose Technology to Measure Response to Treatment in People With Malignant Pleural Mesothelioma

Malignant Pleural Mesothelioma

United States
Alexandria University

Recruiting

Assessment of Nerve Damage Biomarkers in Acute and Chronic Organophosphate Toxicity

Nerve Degeneration | Neurotoxicity | Nerve Injury | Genotoxicity | Neuroinflammatory Response | Nerve Damage

Egypt
Hopital Foch

Recruiting

Analysis of Volatile Organic Compounds in Expired Air in Healthy Volunteers: Comparison of Three Mass Spectrometry Techniques for the Characterization of Volatolome in Clinical Studies (VOC-COMPARE)

Respiratory Disease

France
Virginia Polytechnic Institute and State University
Shady Grove Fertility Reproductive Science Center

Recruiting

The Effect of a Mindset Management Approach on Stress Levels in Women With Infertility

Stress | Infertility, Female

United States
Societa Italiana di Dermatologia Medica, Chirurgica...

Recruiting

Real-world Experience on the Use of Upadacitinib in the Treatment of Moderate-severe Adult Atopic Dermatitis (ERUDA) (ERUDA)

Atopic Dermatitis

Italy
University of Bern
DCB Research AG; Insel Gruppe AG, University Hospital Bern

Recruiting

The Daytime Circadian Rhythm in Exhaled Volatile Organic Compounds in People Living Without and Diabetes (VOCircle)

Diabetes Mellitus

Switzerland
Rambam Health Care Campus

Recruiting

VOC in Breath Samples for the Diagnosis of IPA

Invasive Pulmonary Aspergillosis | Volatile Organic Compounds | Breath Samples

Israel
Orygen
University of Melbourne; Youth Support and Advocacy Service

Recruiting

Guanfacine Extended-release for Adolescents With Cannabis Use (GRACE)

Cannabis Use Disorder

Australia
West Kazakhstan Medical University

Recruiting

Selective Screening of Children for Hereditary Metabolic Diseases by Tandem Mass Spectrometry in Kazakhstan

Ornithine Transcarbamylase Deficiency | Biotinidase Deficiency | Citrullinemia | Glutaric Acidemia Type II | Argininosuccinic Aciduria | Maple Syrup Urine Disease | Primary Carnitine Deficiency | Homocystinuria | Carnitine Palmitoyltransferase II Deficiency | Arginase Deficiency | Very Long-chain Acyl-CoA... and other conditions

Kazakhstan
University of Virginia
National Institutes of Health (NIH); National Institute on Aging (NIA)

Recruiting

Organic Compounds and Postoperative Delirum

Identify Postoperative Delirium Using Exhaled Gas Patterns

United States
Fondation Ophtalmologique Adolphe de Rothschild

Not yet recruiting

Identification of Volatile Organic Compounds (VOCs) as Biopredictors of Epileptic Seizures (ICONE)

Epilepsy
Imperial College London
Royal Marsden NHS Foundation Trust; Chelsea and Westminster NHS Foundation... and other collaborators

Recruiting

COlorectal BReath Analysis (COBRA2)

Colorectal Cancer

United Kingdom
Charite University, Berlin, Germany

Recruiting

Enhancing Educational and Vocational Recovery in Adolescents and Young Adults With Early Psychosis Through Supported Employment and Education. (SEEearly)

Schizophrenia | Schizoaffective Disorder | Acute and Transient Psychotic Disorder, Unspecified | Persistent Delusional Disorder | Other Nonorganic Psychotic Disorders | Unspecified Nonorganic Psychosis

Germany
Purdue University
University of Illinois at Chicago; Indiana University School of Medicine; Mackey...

Recruiting

Addressing Tetrachloroethylene Exposure in an Impacted Community

Cancer | Volatile Organic Compounds | Vapors; Inhalation

United States
Shen Ning

Recruiting

A Pharmacokinetics Study of Meropenem and Piperacillin in Patients With Sepsis (APSOMAPIPWS)

Sepsis | Acute Kidney Injury

China
Cairo University

Not yet recruiting

Efficacy of Coconut Oil With Peppermint Essential for Oral Hygiene Routine

Fluoride Adverse Reaction
Bobbie Baby, Inc

Recruiting

Growth, Tolerance, and Safety Study of Healthy Term Infants Consuming a New Organic Cow's Milk-Based Infant Formula

Healthy Growth

United States
University of Saskatchewan

Recruiting

Beta-alanine Supplementation and CrossFit Performance

Exercise-Induced Lactic Acidemia

Canada
ModernaTX, Inc.

Recruiting

A Retrospective Study to Characterize Participants With Propionic Acidemia

Propionic Acidemia

United States, Spain, Netherlands, France, United Kingdom, Australia, Canada, Italy
Imperial College London
The Leeds Teaching Hospitals NHS Trust; Sheffield Teaching Hospitals NHS Foundation... and other collaborators

Recruiting

Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma (VAPOR)

Pancreatic Cancer | PDAC - Pancreatic Ductal Adenocarcinoma

United Kingdom
Assistance Publique - Hôpitaux de Paris

Recruiting

Volatilomic Approaches for the Study of CFTR Modulators (VOLATIL-CF) (VOLATIL-CF)

Cystic Fibrosis

France
Centre Hospitalier Universitaire de Liege
Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions

Belgium
Cairo University

Recruiting

Evaluation of Clinical Performance of Class IV Restoration Using Organically Modified Ceramic (OMNOCER) in Comparison to a Methacrylate Based Composite Resin

Shade Match

Egypt
Anuja Mitra
British Medical Research Council; The Royal College of Surgeons of England; British...

Not yet recruiting

Augmentation of Volatile Biomarkers of Oesophageal and Gastric Adenocarcinoma From the Tumour Lipidome (AVOCADO)

Gastric Cancer | Diagnoses Disease | Oesophageal Cancer | Breath Test | Augmentation

United Kingdom

Search clinical trials for: Organic Acidemia

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