Search clinical trials for: PDGF alteration

Total 713 results

University of Michigan Rogel Cancer Center

Terminated

Study of Dasatinib in Combination With Everolimus for Children and Young Adults With Gliomas Harboring Platelet-Derived Growth Factor Receptor (PDGFR) Alterations

Glioma | High Grade Glioma | Pontine Tumors

United States
Clovis Oncology, Inc.

Terminated

A Study to Assess the Efficacy and Safety of the VEGFR-FGFR Inhibitor, Lucitanib, Given to Patients With Advanced/Metastatic Lung Cancer and FGF, VEGF, or PDGF Related Genetic Alterations

Small Cell Lung Cancer | Non-Small Cell Lung Cancer | NSCLC | Lung Cancer | Metastatic Lung Cancer | SCLC | Stage IV Lung Cancer | Advanced Lung Cancer | Squamous Non-Small Cell Lung Cancer

United States, Italy, Germany, France, Spain
Lawson Health Research Institute

Not yet recruiting

Cytokine Alterations and Chronic Post-Surgical Pain

Chronic Post Operative Pain
Schweinhardt Petra

Recruiting

State vs. Trait Alterations in Low Back Pain

Low Back Pain

Switzerland
Qian Qin
Janssen, LP; UT Southwestern Comprehensive Cancer Center

Not yet recruiting

Niraparib, Abiraterone Acetate and Prednisone for mHSPC With Deleterious Homologous Recombination Repair Alterations (HARMONY)

BRCA1 Gene Mutation | BRCA2 Gene Mutation | BRIP1 Gene Mutation | PALB2 Gene Mutation | CHEK2 Gene Mutation | FANCA Gene Mutation | RAD51B Gene Mutation | RAD54L Gene Mutation | Metastatic Hormone-sensitive Prostate Cancer (mHSPC) | Deleterious HRR Gene Mutation
3H (Suzhou) Pharmaceuticals Co., Ltd.

Not yet recruiting

A Study of 3HP-2827 in Treatment of Unresectable or Metastatic Solid Tumors With FGFR2 Alterations

Solid Tumors With FGFR2 Alterations, Adult

China
Ruijin Hospital

Not yet recruiting

CAR-T Following ASCT for Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (R/R B-NHL) With High-Risk Prognostic Factors

B-NHL, Extranodal, TP53 Alterations, Bulky Mass
AstraZeneca
Daiichi Sankyo

Recruiting

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations (TROPION-Lung10)

Non-Small Cell Lung Cancer

Spain, Italy, Japan, Brazil, Taiwan, Korea, Republic of, Australia, Austria, Canada, Poland, United States, Belgium, United Kingdom, Turkey, Hungary, Germany, India
Ohio State University

Not yet recruiting

DIAMOND-Lewy Guidelines for Antipsychotic Use in Older Patients

Movement Disorders | Aging | Behavior | Dementia With Lewy Bodies | Emergency Psychiatric | Cognition Disorder | Antipsychotics and Neuroleptics Toxicity | Alteration in Mental Status
Fondazione del Piemonte per l'Oncologia

Recruiting

INSIDE: Identification of Genomic Screening Pathways in Cancer Patients With DNA Repair Alterations (INSIDE)

Prostate Cancer

Italy
Nantes University Hospital

Not yet recruiting

Research Project on the Risk of Discomfort, Pain, Alteration of Skin Condition in Bedpan Use by Patients and Caregivers (RIDAECUBA)

Nurse-Patient Relations

France
Baylor College of Medicine
University of Washington; Fogarty International Center of the National Institute... and other collaborators

Not yet recruiting

Microbiome Alterations With Xylitol (MAX) in Pregnancy (MAX)

Dysbiosis | Inflammation Gum

Malawi
3H (Suzhou) Pharmaceuticals Co., Ltd.

Not yet recruiting

A First-in-human Study of 3HP-2827 in Patients With Unresectable or Metastatic Solid Tumors With FGFR2 Alterations

Solid Tumors With FGFR2 Alterations, Adult

United States
Yale University
University of Pennsylvania

Recruiting

Vitamin D in OUD: Exploration of Alterations on the Dopamine D2/D3 Receptor System

Opioid Use Disorder

United States
University Hospital, Essen

Not yet recruiting

Optimization of Radiation Protection Through Genomic Analyses (ORtogether)

Cancer | Radiation | DNA

Germany
AstraZeneca

Recruiting

Treatment and Biomarker Testing Patterns,Treatment Outcomes in a/m NSCLC With and Without Actionable Genomic Alterations

Non-small-cell Lung Cancer

Russian Federation
Mayo Clinic

Recruiting

Relationship Between Alterations in the GI Microbiome and GI Inflammation on Symptom Burden in Women With Breast Cancer Receiving Chemotherapy

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Longitudinal Assessment of Genomic Alterations and Clonal Evolution in ALK-positive NSCLC (Galileo Project) (GALILEO)

NSCLC Stage IV | ALK Gene Mutation | ALK Sensitizing Mutation

Italy
Tianjin Medical University Cancer Institute and...

Not yet recruiting

Toripalimab Therapy After Resection in High-risk Stage IA2-IB NSCLC With no Driver Alterations (EGFR or ALK)

NSCLC
Çanakkale Onsekiz Mart University

Not yet recruiting

Evaluation of the Effectiveness of Home-Use Desensitizing Agents on Dentin Hypersensitivity

Dentin Sensitivity
Mclean Hospital
Yale University; University of Lausanne

Not yet recruiting

MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction

Cognitive Impairment | Schizophrenia and Related Disorders | Mitochondrial Alteration

United States, Switzerland
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

RC48 Combined With EGFR or HER2 TKI for Locally Advanced or Metastatic NSCLC Patients With HER2 Alterations

Non Small Cell Lung Cancer | ERBB2 Mutation-Related Tumors | Disitamab Vedotin | ERBB2 Gene Duplication
Washington University School of Medicine

Not yet recruiting

Radiation Induced Alterations in Resting State Brain Networks in Pediatric Brain Tumor Patients

Brain Tumor, Primary

United States
Oscar Gerardo Arrieta Rodríguez

Recruiting

Pathogenic Variants in Genes Associated With Lung Adenocarcinoma

Lung Adenocarcinoma

Mexico
Semmelweis University

Recruiting

Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort (POMODORI)

Obesity | Polycystic Ovary Syndrome | Insulin Resistance | Primary Ovarian Insufficiency | Infertility, Female | Mitochondrial Alteration

Hungary
Universidad Autonoma de Nuevo Leon
LifeNet Health; Lynch Biologics LLC

Recruiting

Periodontal Regeneration With Recombinant Human Platelet Derived Growth Factor (rH-PDGF-BB) and Allograft

Periodontal Diseases

Mexico
Tyra Biosciences, Inc

Recruiting

Safety and Anti-Tumor Activity of TYRA-200 in Advanced Cholangiocarcinoma With Activating FGFR2 Gene Alterations (SURF201)

Solid Tumor | Intrahepatic Cholangiocarcinoma | Metastatic Cholangiocarcinoma | Locally Advanced Cholangiocarcinoma

United States
The First Affiliated Hospital of Soochow University

Recruiting

Alterations in Intestinal Microbiota, Metabolites, and Immune Cells in Allo-HSCT

Graft Vs Host Disease

China
Nanjing First Hospital, Nanjing Medical University

Recruiting

Different Positions on the Diffusion and Blockade Effect of Ultrasound-guided Erector Spinae Plane Block

Erector Spinea Plane Block

China
Ruijin Hospital

Recruiting

A Study of the Zanubrutinib Given in Combination With Bendamustine and Rituximab in (Elderly or TP53 Alterations or Chemotherapy Intolerance) Patients With Newly Diagnosed Mantle Cell Lymphoma

Lymphoma, Mantle-Cell

China
Assiut University

Not yet recruiting

Metabolic Alternation and Clinicohematological Characteristic in Chronic Phase CML in Patient Treated With TKI

CML, Chronic Phase
University Hospital, Ghent

Recruiting

HOBBIT 3: Mental Exercises and Temporal Alteration (HOBBIT-META)

Breast Neoplasm | Radiotherapy | Breath Holding | Mental Test

Belgium
Riyadh Elm University

Not yet recruiting

Taste Changes With Fixed Orthodontic Appliances

Taste Perception | Fixed Orthodontic Appliances
St. Joseph's Hospital and Medical Center, Phoenix
Barrow Neurological Institute; Ivy Brain Tumor Center

Recruiting

Study of BDTX-1535 in Recurrent High-Grade Glioma (HGG) Participants With EGFR Alterations or Fusions

High Grade Glioma

United States
Merck Sharp & Dohme LLC

Recruiting

Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004)

Non-small Cell Lung Cancer (NSCLC)

Israel, Taiwan, United States, Australia, Hong Kong, Chile, Korea, Republic of, Canada, Malaysia
Lithuanian University of Health Sciences

Recruiting

Respiratory and Cardiovascular Alterations in Patients With Chronic Obstructive Pulmonary Disease

Cardiovascular Diseases | Quality of Life | Chronic Obstructive Pulmonary Disease Moderate | Chronic Obstructive Pulmonary Disease Severe

Lithuania
Chang Gung Memorial Hospital

Recruiting

The Alterations of Metabolic Adipo-myokines and Body Composition in End Stage Lung Cancer

Lung Cancer Metastatic

Taiwan
Centre Antoine Lacassagne
University of Lyon; University of Firenze and Siena, Napoli, Italy

Recruiting

Individual Food Preferences for the Mediterranean Diet in Cancer Patients (MyPrefMed)

Neoplasms

France
RenJi Hospital

Not yet recruiting

The Influence of the Thickening of Bowman's Capsule on the Clinical Prognosis of Patients With Diabetic Kidney Disease

Diabetic Kidney Disease | Extracellular Matrix Alteration
Cairo University

Not yet recruiting

Effect of Tooth Angulation, Alveolar and Basal Bone Anatomical Characteristics on Soft and Hard Tissue Alterations Around Immediate Implants With Customized Healing Abutment

Immediate Implant | Esthetic Zone | Customized Healing Abutment | Tissue Collapse | Tissue Dimensional Changes
RenJi Hospital
Shanghai Zhongshan Hospital; Ruijin Hospital

Recruiting

A Study of Cadonilimab（AK104） Plus Lenvatinib in Previous Immunotherapy Treated Advanced/Metastatic Clear Cell Renal Cell Carcinoma

Clear Cell Renal Cell Carcinoma、Resistance to Immunotherapy

China
Kura Oncology, Inc.
Mirati Therapeutics Inc.

Recruiting

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors (FIT-001)

Non Small Cell Lung Cancer (NSCLC) | Pancreatic Ductal Adenocarcinoma (PDAC) | Colorectal Cancer (CRC) | Clear Cell Renal Cell Carcinoma (ccRCC) | Solid Tumors With HRAS Alterations

United States
Tianjin Medical University Second Hospital

Recruiting

Pemigatinib for FGF/FGFR Alterations Advanced Pan Solid Tumors

Solid Tumor | FGF Receptor Gene Mutation | FGF Amplification | FGF Receptor Gene Family Rearrangement | FGF Receptor Gene Translocation

China
Stanford University

Not yet recruiting

Alterations in Coagulation Factor Levels in Patients With End Stage Liver Disease

Liver Failure | Liver Cirrhosis | Hemophilia A | Hemophilia B | Hemophilia | Liver Transplant Disorder | Coagulation Factor Deficiency

United States
Chang Gung Memorial Hospital

Recruiting

The Influence of Oral Probiotic on the Vaginal Flora and Microenvironment Alteration in the Vaginosis Infection Women

Probiotic, Human Papillomavirus Infection, Pap Smear, Microbiome

Taiwan
Wake Forest University Health Sciences
Dermavant Sciences, Inc.

Not yet recruiting

Comparison of Post-Inflammatory Pigment Alteration After Psoriasis Treatment (PIPA - Dermavant)

ICD10 Code L40.9 for Psoriasis

United States
New York Medical College

Recruiting

Chemoreflex and Baroreflex Alterations Causing Postural Tachycardia Syndrome With Orthostatic Hyperpnea and Hypocapnia

Hyperventilation | Postural Orthostatic Tachycardia Syndrome | Hypocapnia

United States
Althaia Xarxa Assistencial Universitària de Manresa

Not yet recruiting

Evaluate Efficacy Levobupivacaine 0.125% Versuss Ropivacaine 0.2% in Hemodynamic Alterations in Labor and Fetal Repercussions

Pregnancy | Hemodynamic Instability | Epidural | Fetal Cardiac Disorder

Spain
Se Jun Park

Recruiting

Dabrafenib Plus Trametinib in Patients With Advanced Solid Tumor Having BRAF V600E Mutation or Clinically Actionable BRAF Gene Alterations

Cancer

Korea, Republic of
University Hospital, Clermont-Ferrand

Recruiting

High Intensity Interval Training and Muscle Adaptations During PR (MITOXITRAIN)

Pulmonary Disease, Chronic Obstructive | Oxygen Deficiency | Mitochondrial Alteration

France

Search clinical trials for: PDGF alteration

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