Search clinical trials for: PI-3 kinase inhibitor

Total 82991 results

Life Molecular Imaging Ltd

Recruiting

[18F]PI-2620 Phase 3 Histopathological Study

Alzheimer Disease

United States
Nantes University Hospital

Not yet recruiting

Premorbid Personality Profile of Patients With Cognitive and Behavioral Disorders

Bipolar Disorder | Behavioral Variant of Frontotemporal Disorder (bvFTD) | Phenocopy Frontotemporal Dementia (phFTD) | Frontal Variant of Alzheimer Disease
Ezra Cohen
SignalRX Pharmaceuticals, Inc.

Terminated

SF1126 in Recurrent or Progressive SCCHN and Mutations in PIK3CA Gene and/or PI-3 Kinase Pathway Genes

Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma

United States
Gilead Sciences

Active, not recruiting

Study To Evaluate Emtricitabine/Tenofovir Alafenamide (F/TAF) in Human Immunodeficiency Virus 1 (HIV-1) Infected Children and Adolescents Virologically Suppressed on a 2- Nucleoside/Nucleotide Reverse Transcriptase Inhibitor (2-NRTI)-Containing Regimen

HIV-1

United States, Panama, South Africa
University Tunis El Manar

Unknown

Uterine Artery Pulsatility Index and Materno Fetal Outcomes (UADLAB)

Labor Complication

Tunisia
Spero Therapeutics
Covance

Completed

Study of the Absorption, Metabolism, and Excretion of [14C]-Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) Following a Single Oral Dose in Healthy Male Subjects

Healthy Volunteers

United States
Spero Therapeutics

Completed

Bioequivalence Study Comparing Two Tablet Formulations of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Healthy Adult Subjects

Healthy Volunteers

United States
Peking University Third Hospital

Completed

Relationship Between Spinopelvic Parameters and Clinical Symptoms of Low-grade Lumbar Isthmic Spondylolisthesis

Isthmic Spondylolisthesis

China
Spero Therapeutics
Clinartis

Completed

Study to Assess the Intrapulmonary Pharmacokinetics of SPR859 by Comparing the Plasma, Epithelial Lining Fluid (ELF), and Alveolar Macrophages (AM) Concentrations Following the Oral Administration of Five Doses of SPR994 in Healthy, Nonsmoking Volunteers

Healthy Volunteers

United States
Spero Therapeutics

Completed

Phase 1 Study of PK and Safety of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Subjects With Various Degrees Of Renal Function

Renal Impairment

United States
Vedic Lifesciences Pvt. Ltd.

Completed

Pilot Study to Evaluate Efficacy of Botanical Extracts as Protein Amplifier for Skeletal Muscle Strength & Growth.

Muscle Strength

India
Cellxpert Biotechnology Corp.
Medigen Biotechnology Corporation

Completed

Study of PI-88 in Patients With Advanced Melanoma

Melanoma

United States
Cellxpert Biotechnology Corp.
Medigen Biotechnology Corporation

Completed

PI-88 in Hepatocellular Carcinoma After Hepatectomy

Carcinoma, Hepatocellular

Taiwan
Minia University

Recruiting

AS-OCT Evaluation of Iridocorneal Angle of Patients of Angle Closure Glaucoma After Phacoemulsification

Glaucoma, Angle-Closure

Egypt
University of Alabama at Birmingham
National Institutes of Health (NIH); Mereo BioPharma

Completed

Alvelestat (MPH966) for the Treatment of ALpha-1 ANTitrypsin Deficiency (ATALANTa)

Emphysema or COPD | Alpha-1 Antitrypsin Deficiency (AATD) | Pi*ZZ, Pi*SZ, Pi*Null, Another Rare Phenotype/Genotype Known to be Associated With Either Low or Functionally Impaired AAT Including F or I Mutations

United States
Jae Seung Kim

Completed

Longitudinal Changes of [18F]PI-2620 Positron Emission Tomography in Subjects With Cognitively Normal, Mild Cognitive Impairment and Alzheimer's Disease

Alzheimer Disease | Mild Cognitive Impairment | Cognitively Normal

Korea, Republic of
Peptimmune

Completed

Safety Study of PI-0824 to Treat Pemphigus Vulgaris

Pemphigus Vulgaris

United States
Spero Therapeutics

Completed

A Study to Compare Two Bioanalytical Assays for Tebipenem

Healthy Volunteers

United States
Bright Cell, Inc.

Not yet recruiting

Safety and Efficacy of YB-1113 in Treatment of POI

POI
Asociatia Oncohelp - Centrul de Oncologie Oncohelp
MDX Research

Recruiting

Study Of Real-World Evidence In Patients Treated With Palbociclib During a 2.5 Years Follow-Up Period (PALBO)

Metastatic Breast Cancer

Romania
Life Molecular Imaging SA
Walter Reed National Military Medical Center

Terminated

Imaging [18F]PI-2620 and [18F]Florbetaben in Military Service Members With Blast Related Mild Traumatic Brain Injury

Mild Traumatic Brain Injury

United States
Oslo University Hospital

Completed

A Multi-disciplinary Pain Intervention (MUD-PI) for Patients With Chronic Widespread Primary Pain (MUD-PI)

Chronic Pain, Widespread
Peter MacCallum Cancer Centre, Australia

Terminated

Phase 0 of 18F FPM Using PET/CT in Patients With a Variety of Malignancies

Squamous Cell Carcinoma

Australia
Amgen

Completed

FIRST - Study of Pegfilgrastim Administered in the First and Subsequent Cycles of Myelosuppressive Chemotherapy

Neutropenia
Assiut University

Recruiting

Perfusion Index in Assessment of Postoperative Pain in Children.

Postoperative Pain

Egypt
Asan Medical Center
Korea Health Industry Development Institute

Completed

Evaluation of [18F]PI-2620 as a Potential Positron Emission Computed Tomography Radioligand for Imaging Tau Protein in the Brain

Parkinson Disease | Alzheimer Disease | Healthy Volunteer | Frontotemporal Dementia

Korea, Republic of
Macquarie University, Australia
Life Molecular Imaging GmbH; Omniscient Neurotechnology

Active, not recruiting

Tau And Connectomics In TES Study (TACIT)

Neurodegenerative Diseases | Cognitive Impairment | Head Injury Trauma | Chronic Traumatic Encephalopathy | Traumatic Encephalopathy

Australia
Paracelsus Medical University

Completed

Improving Prostate Lesion Classification and Development of a PI-RADS 3 Classifier

Prostate Cancer

Germany
Federal University of Uberlandia
Adriano de Oliveira Andrade

Not yet recruiting

Heart Rate Variability of Premature Newborn (HRV)

Autonomic Nervous System Imbalance
Chonbuk National University Hospital

Completed

Efficacy and Safety of Nokyong Mixture Extract(CME-PI) on Promotion of Immunity

Immunity

Korea, Republic of
Techfields Inc

Terminated

Evaluate the Efficacy and Safety of TF0023 in Treatments for COVID-19 in Hospitalized Adults

COVID-19 Pneumonia

United States, South Africa
Johannes Gutenberg University Mainz

Completed

Perfusion Index (PI) and Pleth Variability Index (PVI) in Patients With Interscalene Blocks in Orthopedic Surgery (PI-PVI)

Orthopedic Surgery | Perfusion Index and Pleth Variability Index | Interscalene Blocks

Germany
Moscow Regional Research and Clinical Institute...

Terminated

Comparison of the Effects of TIVA vs VIMA on Content of GSK-3beta in Leucocytes in On-pump Patients

Glycogen Synthase Kinase 3

Russian Federation
University of Pennsylvania
Yale University

Recruiting

Tau PET Imaging in Opioid Use Disorder

Opioid-Related Disorders

United States
Genentech, Inc.

Completed

Evaluation Comparing Tau PET Radiotracers, [18F]GTP1 and [18F]PI-2620 or [18F]MK-6240 in Subjects With Normal Cognition or Prodromal to Moderate Alzheimer's Disease

Alzheimer Disease (AD)

United States
Cubist Pharmaceuticals LLC

Completed

A Study of Alvimopan for the Management of Postoperative Ileus in Participants Undergoing Radical Cystectomy

Postoperative Ileus

United States
Yu Zhang

Not yet recruiting

Study on the Regulatory Effects of Personalized Innovative Youtiao Intervention on Nutritional Health

Metabolism and Nutrition Disorder
University of Southern California
National Institute on Aging (NIA); Northern California Institute of Research... and other collaborators

Recruiting

Alzheimer's Disease Neuroimaging Initiative 4 (ADNI4)

Dementia | Alzheimer Disease | Mild Cognitive Impairment

United States, Canada
University of North Texas Health Science Center

Enrolling by invitation

Health and Aging Brain Study: Health Disparities Tau Positron Emission Tomography (PET) Scan Study

Alzheimer Disease

United States
University of Oklahoma
GlaxoSmithKline

Terminated

PARP Inhibition for Gliomas (PI-4G or π4g) (OU-SCC-PI-4G)

Recurrent Glioblastoma | Recurrent Glioma | Recurrent Astrocytoma | Recurrent Oligodendroglioma

United States
Muğla Sıtkı Koçman University

Completed

SMAD2, SMAD3 AND TGF-β GENE EXPRESSION IN URGE URINARY INCONTINENCE

Pelvic Organ Prolapse | Urge Urinary Incontinence | SMAD2 | SMAD3 | TGF-β

Turkey
Case Western Reserve University
National Institute on Minority Health and Health Disparities (NIMHD)

Completed

University Student Intervention to Increase Organ Donation

Health Behavior | Organ Donation

United States
Pi-cardia

Active, not recruiting

The Leaflex™ Standalone Study Protocol

Aortic Valve Stenosis

Hungary
Assiut University

Not yet recruiting

Effect of Sodium and UF Profiling on Dialysis

Dialysis; Complications
Galenic Research Institute Ltd

Completed

Local mEHT + TCM Versus Intraperitoneal Chemoinfusion in Treatment of Malignant Ascites: Phase II RCT (OTMA-RII)

Peritoneal Neoplasms | Ascites | Yin Deficiency | Yang Deficiency

China
Debiopharm International SA

Terminated

Alisporivir With PEG and RBV in Protease Inhibitor (PI) Treatment Failure Patients With Chronic Hepatitis C

Hepatitis C

United States, Germany, France, Spain, Italy, United Kingdom, Puerto Rico, Canada
KU Leuven

Completed

Post-Infectious Irritable Bowel Syndrome (PI-IBS) (PI-IBS)

Irritable Bowel Syndrome With Diarrhea

Belgium
Cellxpert Biotechnology Corp.
Medigen Biotechnology Corporation

Completed

PI-88 in Treating Patients With an Advanced Malignancy (Cancer) or Stage IV Melanoma

Unspecified Adult Solid Tumor, Protocol Specific | Melanoma (Skin)

Australia, United States
IRCCS Fondazione Stella Maris

Completed

Testing Miglustat Administration in Subjects With Spastic Paraplegia 11 (TreatSPG11)

Hereditary Spastic Paraparesis

Italy
Gruppo Oncologico del Nord-Ovest

Unknown

Folfoxiri Plus Bev Followed by Reintroduction of Folfoxiri Plus Bev at Progression Versus Folfox Plus Bev Followed by Folfiri Plus Bev in mCRC (TRIBE2)

Metastatic Colorectal Cancer

Italy

Search clinical trials for: PI-3 kinase inhibitor

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