Search clinical trials for: PROPEL

Total 103 results

GlaxoSmithKline

Not yet recruiting

A Study to Compare the Relative Potency of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152a to HFA-134a in Mild Asthmatics Aged 18 to 65 Inclusive

Asthma | Mild Asthma
GlaxoSmithKline

Not yet recruiting

A Study to Compare the Pharmacokinetics (PK) of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152A (Test) or HFA-134A (Reference) in Healthy Participants Aged 18 to 55 Inclusive

Asthma | Healthy Participants

Netherlands
AstraZeneca
Parexel

Not yet recruiting

A Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C)

Healthy

Germany
Inozyme Pharma
GACI Global

Not yet recruiting

PROPEL - A Prospective Observational Patient Registry to Evaluate ENPP1 and ABCC6 Deficiency

ATP-Binding Cassette Subfamily C Member 6 Deficiency | Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 Deficiency
AstraZeneca

Recruiting

A Study to Assess the Pharmacokinetics and Safety of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C).

Chronic Obstructive Pulmonary Disease

Germany, United Kingdom
Chiesi Farmaceutici S.p.A.

Recruiting

Comparison Between CHF5993 pMDI 200/6/12,5mg HFA-152a VS CHF5993 pMDI 200/6/12,5mg HFA-134a in Subjects With Asthma (Trecos) (TRECOS)

Asthma

United Kingdom
GlaxoSmithKline

Not yet recruiting

A Study to Assess and Compare Safety and Tolerability of 3 Months Treatment With Salbutamol Administered Via MDI Containing Propellant HFA-152a or HFA-134a in Participants 12 Years of Age and Older With Asthma

Asthma

Argentina, United States, Canada, Panama, Greece, France, Poland, Italy, United Kingdom
University of Ottawa

Not yet recruiting

Education to Improve Pneumococcal Vaccine Uptake Among Older Adults (PROPEL)

Pneumococcal Vaccine Uptake | Vaccination Willingness | Pneumococcal Vaccine Knowledge | Pneumococcal Vaccine Attitude

Canada
Milap Sandhu
University of Florida; Baylor Scott and White Health

Recruiting

Promoting Recovery Outcomes Through Precise Early Locomotor Interventions in Persons With Spinal Cord Injury (PROPEL-SCI)

Spinal Cord Injuries

United States
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); Georgetown University

Recruiting

Personalized Oncology Promoting Equity for Black Lives (PROPEL)

Hereditary Cancer | Genetic Testing

United States
AstraZeneca

Recruiting

A Study to Investigate the Effect on Lung Function of an Approved COPD Treatment (BGF, With HFA Propellant) Compared to BGF Formulated With a New Propellant (HFO) in Participants 40 to 80 Years of Age With COPD

COPD (Chronic Obstructive Pulmonary Disease)

United States, Korea, Republic of, Argentina, Turkey, Vietnam, Malaysia, Philippines, Thailand, Hungary, Mexico, Canada, India, Bulgaria, Poland
University of Colorado, Denver
United States Department of Defense

Recruiting

Advair HFA in Healthy and HAPE Predisposed Subjects (SWIFTARC)

Altitude Edema

United States
Royal College of Surgeons, Ireland

Recruiting

PROPEL-2: Prophylactic Negative Pressure Wound Therapy in Laparotomy Wounds (PROPEL-2)

Wound Infection | Cosmesis | Wound Surgical

Ireland
Medtronic

Recruiting

Propel Drug-Eluting Sinus Stent Family

Chronic Rhinosinusitis (Diagnosis)

United Kingdom, Germany
my mhealth Ltd
University of Southampton; University Hospitals Bristol and Weston NHS Foundation... and other collaborators

Recruiting

A Pragmatic Real-world Multicentre Observational Research Study to Explore the Clinical and Health Economic Impact of myCOPD (PROPEL myCOPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
AstraZeneca

Recruiting

Study to Assess Effect of HFO MDI Propellant on Mucociliary Clearance Compared to HFA MDI Propellant in Healthy Participants

Mucociliary Clearance

United States
LMU Klinikum
Seventh Framework Programme; NBIA Alliance

Recruiting

TIRCON International NBIA Registry (TIRCON)

Neurodegeneration With Brain Iron Accumulation (NBIA) | Pantothenate Kinase-associated Neurodegeneration (PKAN) | Aceruloplasminemia | Beta-Propeller Protein-Associated Neurodegeneration (BPAN) | Mitochondrial Membrane Protein Associated Neurodegeneration (MPAN) | Fatty Acid Hydroxylase-associated... and other conditions

Canada, Czechia, Germany, Italy, Netherlands, Poland, Serbia, Spain
University Health Network, Toronto

Recruiting

PRehab tO PreparE Living Liver Donors for Enhanced Recovery (PROPELLER)

Living Donor Liver Transplantation

Canada
SwanBio Therapeutics, Inc.

Recruiting

A Study to Evaluate Administration of SBT101 Gene Therapy in Adult Patients With Adrenomyeloneuropathy (AMN) (PROPEL)

AMN | AMN Gene Mutation | X-ALD

Netherlands, United States
OssDsign

Recruiting

OssDsign® Spine Registry Study ("Propel")

Degenerative Disc Disease | Spinal Stenosis

United States
STS Medical

Not yet recruiting

Efficacy of ArchSinus, NasoPore & Propel to Prevent Post-Surgical MT Lateralization and Improve Symptomatic Outcomes

Chronic Sinusitis
Propella Therapeutics

Recruiting

Open-label, Multicenter Study of Intramuscular PRL-02 Depot in Patients With Advanced Prostate Cancer

Prostate Cancer | mCRPC | mCSPC

United States
University of Bern
Kantonsspital Aarau; Kantonsspital Winterthur KSW; Kantonsspital Graubünden; Hospital... and other collaborators

Not yet recruiting

Stibium Metallicum Praeparatum 6x Versus Placebo in the Prevention of Paclitaxel-induced Peripheral Neurotoxicity (PROPEL NO TOX)

Chemotherapy Induced Peripheral Neuropathy (CIPN)
Prevail Therapeutics
Eli Lilly and Company

Recruiting

Phase 1/2a Clinical Trial of PR001 (LY3884961) in Patients With Parkinson's Disease With at Least One GBA1 Mutation (PROPEL)

Parkinson Disease

United States, Israel
Marina Boruk
State University of New York - Downstate Medical Center

Not yet recruiting

Adjunctive Treatment for Chronic Rhinosinusitis With Nasal Polyposis

Nasal Polyps | Chronic Rhinosinusitis

United States
Susan J. Hayflick
Oregon Health and Science University

Recruiting

NBIAready: Online Collection of Natural History Patient-reported Outcome Measures

Neurodegeneration With Brain Iron Accumulation (NBIA)

United States
AstraZeneca

Completed

Study to Assess the Pharmacokinetic Bioequivalence of Budesonide and Albuterol With an Alternate Propellant Compared to Current Propellant.

Heathy Participants

United States
QED Therapeutics, Inc.

Enrolling by invitation

A Study to Evaluate the Efficacy and Safety of Infigratinib in Children and Adolescents With Achondroplasia (PROPEL3)

Achondroplasia

Australia, United States, Argentina, Canada, France, Germany, Italy, Norway, Singapore, Spain, United Kingdom
AstraZeneca

Completed

A Study to Assess the Safety of Budesonide/Glycopyrronium/Formoterol Fumarate With the Hydrofluoroolefin Propellant in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease (COPD)

United States, Canada, Germany, Argentina, Bulgaria, Poland, Turkey, Mexico, United Kingdom
Novartis Pharmaceuticals

Completed

Digital Adherence Monitoring of Inhalative Therapy in Real- Life Conditions (ADITION)

Asthma

Germany
Propella Therapeutics

Completed

A Phase 2 Clinical Trial Examining the Effects on Osteoarthritic Knee Pain of CGS-200-1, CGS-200-5 and Vehicle Control

Pain | Osteoarthritis, Knee

United States
Propella Therapeutics
Palm Beach Research, Inc

Completed

Osteoarthritis Knee Pain Relief Study of 0.25% 920-CGS-200

Osteoarthritis, Knee

United States
Pennington Biomedical Research Center
University of Alabama at Birmingham; National Institute on Minority Health... and other collaborators

Active, not recruiting

Promoting Successful Weight Loss in Primary Care in Louisiana Using Information Technology (PROPEL-IT)

Obesity | Diabetes Mellitus, Type 2 | PreDiabetes

United States
MacroGenics

Completed

A Study of MGD013 in Patients With Unresectable or Metastatic Neoplasms

Cervical Cancer | Hematologic Neoplasms | Ovarian Cancer | Non Small Cell Lung Cancer | Advanced Solid Tumors | Squamous Cell Carcinoma of Head and Neck | Cholangiocarcinoma | Small-cell Lung Cancer | TNBC - Triple-Negative Breast Cancer | HER2-positive Advanced Solid Tumors

Hong Kong, United States, Thailand, Australia, Spain, Bulgaria, Poland, Ukraine
University of Connecticut
National Institute of Nursing Research (NINR)

Completed

Physical Activity on Neurophysiologic Gene Expression Profiles of Chronic Low Back Pain (PROPEL)

Chronic Low Back Pain | Self-Management

United States
Toronto Rehabilitation Institute
McMaster University; Hamilton Health Sciences Corporation; West Park Healthcare... and other collaborators

Terminated

PROPEL Randomized Trial

Stroke

Canada
Effector Therapeutics
Medpace, Inc.

Completed

Intravenous Zotatifin in Adults With Mild or Moderate COVID-19 (PROPEL)

Corona Virus Infection

United States
AstraZeneca

Completed

Study to Assess Bronchospasm Potentially Induced by HFO vs HFA MDI in Participants With Well/Partially Controlled Asthma

Asthma

United States
Connecticut Children's Medical Center

Completed

Feasibility and Acceptability of the Propeller Monitoring System in Children With Persistent Asthma

Asthma

United States
Chiesi Farmaceutici S.p.A.

Completed

Study to Assess the Effect of the New HFA-152a Propellant on Mucociliary Clearance

Mucociliary Clearance

United Kingdom
Amicus Therapeutics

Completed

A Study Comparing ATB200/AT2221 With Alglucosidase Alfa/Placebo in Adult Subjects With Late-onset Pompe Disease (PROPEL)

Pompe Disease (Late-onset)

United States, Australia, Korea, Republic of, Japan, Taiwan, Belgium, Slovenia, New Zealand, United Kingdom, France, Argentina, Canada, Spain, Bosnia and Herzegovina, Germany, Sweden, Hungary, Austria, Bulgaria, Denmark, Greece, I... and more
Galvanize Therapeutics, Inc.

Terminated

Galvanize Prospective/Retrospective Pulsed Electric Field Device Registry (PROPEL)

Soft Tissue Lesion

United States
Lisa Levine

Terminated

Propranolol Rescue of Prolonged Labor (PROPEL)

Pregnancy, Prolonged

United States
Haukeland University Hospital

Active, not recruiting

Protocol for Patients Above 75 Years Undergoing Emergency Laparotomy ((ProPEL))

Frail Elderly Syndrome | Frailty | Surgery--Complications | Outcome, Fatal | Post-Op Complication | Gastro-Intestinal Disorder

Norway
Pennington Biomedical Research Center
Patient-Centered Outcomes Research Institute; Tulane University; Louisiana State... and other collaborators

Completed

Promoting Successful Weight Loss in Primary Care in Louisiana (PROPEL)

Obesity

United States
United Orthopedic Corporation

Active, not recruiting

Prospective Post Approval Clinical Follow-Up Study of the Commercially Available U2 Knee™ System - "U-Propel Study" (U-Propel)

Osteo Arthritis Knee

United States
AstraZeneca
Parexel

Completed

A Study to Assess the Total Systemic Exposure Bioequivalence of of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI HFO Compared With BGF MDI HFA

Chronic Obstructive Pulmonary Disease

United States
AstraZeneca
Parexel

Completed

Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI HFO Compared With BGF MDI HFA

Chronic Obstructive Pulmonary Disease

United States
Intersect ENT

Completed

A Clinical Evaluation of PROPEL® Contour Sinus Implant (EXPAND)

Chronic Rhinosinusitis (Diagnosis)

United States
Nektar Therapeutics

Terminated

Bempegaldesleukin and Pembrolizumab With or Without Chemotherapy in Locally Advanced or Metastatic Solid Tumors (PROPEL)

Non-Small Cell Lung Cancer

United States, Germany, Spain, Australia, France

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