Search clinical trials for: Pharmacokinetics and dynamics

Total 474499 results

4TEEN4 Pharmaceuticals GmbH

Recruiting

Phase 1 Study to Evaluate Safety, Tolerability and Pharmacokinetics/-Dynamics of AK1967 (Procizumab)

Safety and Tolerability

Netherlands
Erasmus Medical Center

Recruiting

Maternal and Fetal/Neonatal Pharmacokinetics and - Dynamics of Corticosteroids During Pregnancy (MaDyCo)

Preterm Birth

Netherlands
Amsterdam UMC, location VUmc

Not yet recruiting

Alternative Dosing Scheme of Pomalidomide 4 mg Every Other Day Versus Pomalidomide 2 mg and 4 mg Every Day; the POMAlternative Study (POMAlternative)

Multiple Myeloma | Multiple Myeloma in Relapse | Multiple Myeloma, Refractory
Children's Hospital Medical Center, Cincinnati

Recruiting

Therapeutic Response Evaluation and Adherence Trial (TREAT) (TREAT)

Anemia, Sickle Cell

United States
Baylor College of Medicine

Withdrawn

Peppermint Oil Pharmacokinetics/Dynamics

Abdominal Pain

United States
Amsterdam UMC, location VUmc
ADHDcentraal

Completed

The Day-time Response Variation of (Lis)Dexamphetamine (IDEAL)

Adhd

Netherlands
Daiichi Sankyo, Inc.

Completed

Study to Assess the Safety, Pharmacokinetics/Dynamics of DS-1040b in Subjects With Acute Submassive Pulmonary Embolism

Pulmonary Embolism | Thrombotic Disease

Netherlands, Spain, United States, France, Austria, Belgium, Germany, Italy
Robert Shulman, M.D.

Completed

Peppermint Oil Pharmacokinetics/Dynamics and Novel Biological Signatures in Children With Functional Abdominal Pain (PMO)

Abdominal Pain

United States
University of California, San Diego
University of California, Los Angeles; GlaxoSmithKline; University of Southern... and other collaborators

Completed

Viral Dynamics and Pharmacokinetics of Abacavir and Tenofovir

HIV Infections

United States
Assiut University

Completed

Pharmacokinetics and Dynamics of Dexmedetomidine as Adjuvant in TAP Block

Postoperative Pain

Egypt
University of California, San Francisco
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Open...

Completed

The Effects of BCRP Q141K on Allopurinol Pharmacokinetics and Dynamics

Hyperuricemia | Chronic Gout

United States
EVIVE Biotechnology
Sun Yat-sen University; Fudan University

Completed

A Pharmacokinetics/Dynamics Ib Study of F-627 in Women With Breast Cancer Receiving Myelotoxic Chemotherapy

Neutropenia

China
Assiut University

Unknown

Pharmacokinetics and Dynamics of Nebulized Dexmedetomidine

Abdominal Cancer

Egypt
GlaxoSmithKline

Completed

Effect of GSK1399686 in Patients With Mild to Moderately Active Ulcerative Colitis

Colitis, Ulcerative

Sweden, Germany, Belgium, Canada, Norway
University Hospital, Bonn

Completed

Temporal Dynamics and Pharmacokinetics of Intranasally Administered Oxytocin

Healthy

Germany
Clinica Universidad de Navarra, Universidad de...

Completed

Therapeutic Individualization for Patients With Locally Advanced Gastric and Gastroesophageal Cancer

Gastric Cancer | Surgery | Effects of Chemotherapy

Spain
Assistance Publique - Hôpitaux de Paris

Terminated

Calcineurin Activity in Renal Recipients

Renal Transplant Rejection

France
Boehringer Ingelheim

Completed

Tolerability and Pharmacokinetics/-Dynamics of Single Rising Doses BIBT 986 BS in Healthy Male Subjects

Healthy
Boehringer Ingelheim

Completed

Tolerability and Pharmacokinetics/-Dynamics of BIBT 986 BS in Healthy Male Subjects

Healthy
Boehringer Ingelheim

Terminated

Safety, Tolerability, Pharmacokinetics and -Dynamics of Multiple Rising Oral Doses of BI 113823 in Patients Patients With Osteoarthritis of the Knee

Osteoarthritis

Germany
Osaka University

Withdrawn

Randomized Trial for Pharmacogenomics-based Proton Pump Inhibitor Therapy in Children

Gastroesophageal Reflux

Japan
AOP Orphan Pharmaceuticals AG

Completed

A Short Term Pharmacokinetic, Pharmacodynamic and Tolerability Study to Compare AOP200704 vs. Esmolol

Healthy Volunteers | Pharmacokinetics/Dynamics Study

Czech Republic
AVEO Pharmaceuticals, Inc.

Completed

A Cardiac Safety Study of Tivozanib to Evaluate the Electrocardiogram and Pharmacokinetic-Electrocardiogram Dynamics in Subjects With Advanced Solid Tumors

Advanced Solid Tumors

United States
Universitaire Ziekenhuizen KU Leuven

Completed

Pharmacokinetics, -Dynamics and Safety of Intravenous Paracetamol in Neonates (PARANEO)

Pain | Fever

Belgium
Becton, Dickinson and Company

Completed

Pharmacokinetics/Dynamics of Basal (Continuous) Insulin Infusion Administered Either Intradermally or Subcutaneously

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1

Germany
National Institute of Mental Health (NIMH)

Completed

Dynamics of Leptin and Endocrine Function

Healthy | Involutional Depression

United States
Novartis

Completed

Effects of Water and Food Intake on the Pharmacokinetics and Pharmacodynamics of Oral Salmon Calcitonin in Healthy Postmenopausal Women

Postmenopausal Osteoporosis

Denmark
Novartis

Completed

Pharmacokinetics and Pharmacodynamics Study of Oral Salmon Calcitonin in Healthy Postmenopausal Women

Postmenopausal Osteoporosis

Denmark
AstraZeneca

Not yet recruiting

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AZD5148 in Healthy Adults

Healthy Participants

United States
Longevity Biotech Australia Pty Ltd (subsidiary)

Not yet recruiting

A Two-Part Single and Multiple Ascending Dose Trial of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LBT-3627 in Healthy Participants and in Participants With Parkinson's Disease.

Parkinson Disease

Australia
University Hospital, Strasbourg, France

Recruiting

Optimizing the Management of Sickle Cell Patients on Hydroxyurea: The Value of Therapeutic Pharmacological Monitoring (OPTIMDREP)

Sickle Cell Disease

France
MBX Biosciences

Recruiting

Safety, Pharmacokinetics and Efficacy of MBX 2109 in Patients With Hypoparathyroidism

Hypoparathyroidism

United States
Il-Yang Pharm. Co., Ltd.

Not yet recruiting

Clinical Trial to Investigate the Effects of Food on the Pharmacokinetics and Safety of Orally Administered Radotinib

Drug Kinetics

Korea, Republic of
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Analysis of the Influence of Gastric By-Pass on the Pharmacokinetics of Common Drugs (ABSORGYP)

Bypass Bariatric Surgery

France
Leslie E. Roos
Canadian Institutes of Health Research (CIHR); Children's Hospital Research... and other collaborators

Recruiting

Building Emotional Awareness and Mental Health (BEAM) 2024-2027 (BEAM)

Anger | Stress, Psychological | Parent-Child Relations | Parenting | Child Development | Depression, Anxiety

Canada
Zhejiang Sunshine Mandi Pharmaceutical Co.,Ltd.

Not yet recruiting

Pharmacokinetics, Safety and Tolerability of Clascoterone Cream 1% in Healthy Chinese Adult Subjects

Acne Vulgaris
Universität des Saarlandes

Recruiting

Pharmacokinetics of Bisoprolol and SGLT2i in Acutely Decompensated Heart Failure (BISO-ADHF)

Acute Decompensated Heart Failure

Germany
Tonghua Dongbao Pharmaceutical Co.,Ltd

Recruiting

A Trial to Investigate the Single Dose Pharmacokinetics of Insulin Degludec/Liraglutide in Healthy Chinese Subjects

Healthy

China
Shanghai Jiaolian Drug Research and Development...
Shanghai Pharmaceuticals Holding Co., Ltd

Not yet recruiting

A Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of SV001 in Chinese Healthy Adult Volunteers.

Generalized Myasthenia Gravis

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacokinetic of TQB3702 Tablets in Healthy Adult Subjects

Systemic Lupus Erythematosus

China
Institut du Cancer de Montpellier - Val d'Aurelle

Not yet recruiting

Dynamics of Motivational Factors for Physical Activity and Nutrition in Oncogeriatrics (MONAGE)

Cancer

France
LEO Pharma

Not yet recruiting

A Study to Evaluate Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of LEO 158968

Joint Pain | Gout Flares | Joint Inflammation
Eli Lilly and Company

Not yet recruiting

A Study to Compare Tablets and Capsules of Orforglipron (LY3502970) in Healthy Participants Who Are Obese or Overweight

Healthy | Obesity | Overweight | Obese

United States
Nanexa AB
Profil Institut für Stoffwechselforschung GmbH

Not yet recruiting

Phase 1 Study Assessing the Pharmacokinetics of NEX-22A in Subjects With T2D

Type 2 Diabetes
Daewoong Pharmaceutical Co. LTD.

Not yet recruiting

to Evaluate the Safety/Tolerability and Pharmacokinetics, and Pharmacodynamics of DWP14012 Injection

Erosive Gastroesophageal Reflux Disease
GlaxoSmithKline

Not yet recruiting

A Study to Compare the Pharmacokinetics (PK) of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152A (Test) or HFA-134A (Reference) in Healthy Participants Aged 18 to 55 Inclusive

Asthma | Healthy Participants

Netherlands
Rallybio IPA, LLC

Not yet recruiting

Phase 2 Study on the Pharmacokinetics and Safety of RLYB212 in Pregnant Women at Higher Risk for HPA-1a Alloimmunization

Fetal and Neonatal Alloimmune Thrombocytopenia
Innovative Molecules GmbH

Recruiting

Phase I Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single Doses of IM-250 in Healthy Volunteers

Herpes Simplex Virus

Germany
Atrogi AB

Recruiting

The Attractive 2 Trial - Pharmacokinetics of ATR-258 Oral Capsule vs. Oral Solution Formulations in Healthy Volunteers (Attractive 2)

Type2diabetes

Sweden
Ove Andersen
Mayo Clinic; University of Southern Denmark

Not yet recruiting

Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With Multimorbidity

Healthy | Multimorbidity

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