Search clinical trials for: Pharmacokinetics of cyclosporine

Total 430032 results

AstraZeneca
Parexel

Completed

Study to Assess the Effect of Sodium Zirconium Cyclosilicate on the Pharmacokinetics of Tacrolimus and Cyclosporin in Healthy Subjects

Hyperkalaemia

Germany
Novartis Pharmaceuticals

Active, not recruiting

A Phase II Dose-escalation Study Characterizing the PK of Eltrombopag in Pediatric Patients With Previously Untreated or Relapsed Severe Aplastic Anemia or Recurrent Aplastic Anemia

Aplastic Anemia

Thailand, Russian Federation, Portugal, United Kingdom, Hong Kong, United States
Shanghai Vinnerna Biosciences Co., Ltd.

Active, not recruiting

Effect of Pharmacokinetics in Healthy Chinese Subjects

The Effects of Clarithromycin or Cyclosporine on Pharmacokinetics of Deuterium Hydrobromide Ramidvir Tablets in Healthy Chinese Subjects

China
Pfizer

Completed

A Drug-Drug Interaction Study to Examine the Impact of Itraconazole and Cyclosporine on PF-07081532 Pharmacokinetics in Overweight or Obese Adults

Healthy

United States
Alexion

Completed

Drug-Drug Interaction (DDI) Study of ALXN2050 in Healthy Adult Participants

Healthy

United States
AstraZeneca
Parexel

Completed

Pharmacokinetics of Verinurad and Allopurinol in Combination With Cyclosporine and Rifampicin in Healthy Volunteers

Chronic Kidney Disease

Germany
Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Effect of Cyclosporine on the Pharmacokinetics (PK) of AT-527 (R07496998)

Healthy Volunteer Study

Canada
University of Saskatchewan
Saskatchewan Health Research Foundation; Lung Association of Saskatchewan

Completed

Drug Interaction Study of Apixaban With Cyclosporine or Tacrolimus in Transplant Recipients (ACT-KLR)

Pharmacokinetics | Lung Transplant | Kidney Transplant

Canada
Janssen R&D Ireland

Completed

A Study of Pharmacokinetics, Efficacy, Safety, Tolerability, of the Combination of Simeprevir (TMC435), Daclatasvir (BMS-790052), and Ribavirin (RBV) in Patients With Recurrent Chronic Hepatitis C Genotype 1b Infection After Orthotopic Liver Transplantation

Hepatitis C, Chronic

Spain, Germany, Poland
GlaxoSmithKline

Completed

Drug-drug Interaction Study of Eltrombopag and Cyclosporine in Healthy Subjects

Purpura, Thrombocytopenic, Idiopathic

United States
Thomas Jefferson University
Bristol-Myers Squibb

Completed

Drug Interaction Study of Apixaban With Cyclosporine and Tacrolimus (ACT)

Healthy | Venous Thromboembolism | Pharmacokinetics

United States
Hoffmann-La Roche

Terminated

Safety, Tolerability and Pharmacokinetics of Oral CellCept (Mycophenolate Mofetil) in Pediatric Liver Transplant Recipients on Concomitant Treatment With Cyclosporine and Corticosteroids

Pediatric Liver Transplantation

United States
Sigmoid Pharma

Completed

PK, Safety & Tolerability of CyCol® Versus Sandimmune® in Healthy Subjects (CYC102)

Healthy
University of Oslo School of Pharmacy

Completed

Interaction Between Rimonabant and Cyclosporine and Tacrolimus (RIMONA-PILOT)

Renal Transplantation

Norway
NeuroVive Pharmaceutical AB

Completed

A Study to Compare the Bioavailability and Pharmacokinetics of Cyclosporine After Intravenous Administration of NEUROSTAT®, a CREMOPHOR® EL-free Lipid Emulsion, and SANDIMMUNE® Injection (a Suspension of Cyclosporine in CREMOPHOR® EL) in Healthy Volunteers

Healthy

South Africa
Astellas Pharma Inc
Astellas Pharma Canada, Inc.

Completed

Comparison of Extended Release Tacrolimus (Advagraf) and Cyclosporine A Microemulsion on Renal Function in Healthy Volunteers

Healthy

Canada
University Hospital, Limoges

Completed

Pharmacokinetics of Immunosuppressive Drugs in Heart Transplant Patients (PIGREC)

Heart Transplant

France
AstraZeneca

Completed

Study to Assess Effect of Cyclosporine on the Blood Levels of Ticagrelor

Healthy

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Assess the Effects of Cyclosporine on the Pharmacokinetics and Safety of Canagliflozin (JNJ-28431754) in Healthy Volunteers

Healthy

Belgium
University of Oslo School of Pharmacy

Completed

Effects of Cyclosporine A on Pancreatic Insulin Secretion

Chronic Renal Failure

Norway
Tibotec Pharmaceuticals, Ireland

Completed

A Study in Healthy Participants Investigating the Effect of TMC435 on the Pharmacokinetics of Immunosuppressants Cyclosporine and Tacrolimus

Hepatitis C Virus

Belgium
University of Sao Paulo

Completed

Pharmacokinetics of Cyclosporin in Nephrotic Syndrome

Nephrotic Syndrome

Brazil
Astellas Pharma Inc
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Isavuconazole and Cyclosporine

Healthy

United States
Pfizer

Completed

Single Dose Study Of The Effect Of Cyclosporine On The Pharmacokinetics Of PF-04991532 In Health Volunteers

Healthy | Drug Interaction

Belgium
Vertex Pharmaceuticals Incorporated
Tibotec Pharmaceutical Limited

Completed

A Study to Examine the Effects of Telaprevir on the Pharmacokinetics of Cyclosporine and Tacrolimus in Healthy Adults

Hepatitis C

United States
Mutual Pharmaceutical Company, Inc.

Completed

Drug-Drug Interaction Study Between Colchicine and Cyclosporine

Healthy | Pharmacokinetics

United States
Pfizer

Completed

A Phase I Open-Label Study of the Effects of Tacrolimus and Cyclosporine on CP-690,555 in Healthy Volunteers

Healthy Volunteers

Singapore
University Hospital, Antwerp
Novartis Pharmaceuticals; University of Liege; University Hospital, Ghent; Universitair... and other collaborators

Unknown

Calcineurin Inhibitor (CNI) Versus Steroid Cessation in Renal Transplantation (CISTCERT)

Renal Transplantation

Belgium
Norgine

Completed

Evaluation of the Pharmacokinetics of NRL972 Following Pre-Administration of Rifampicin and Cyclosporine

Pharmacokinetics

Bulgaria
National Cancer Institute (NCI)

Completed

A Phase I Study of Infusional Chemotherapy With the P-Glycoprotein Antagonist PSC 833

Lymphoma | Breast Cancer | Neoplasm Metastasis | Ovarian Cancer | Kidney Neoplasm

United States
Charite University, Berlin, Germany
Novartis

Completed

Pharmacokinetics of Everolimus and Enteric-Coated Mycophenolatesodium Before and After Withdrawal of Cyclosporine in Renal Transplant Patients

Renal Transplantation

Germany
National Taiwan University Hospital

Unknown

The Pharmacokinetics of Sirolimus When Combined With Cyclosporine or Tacrolimus in Renal Transplant Patients

Kidney Transplantation | Immunosuppression | Transplantation

Taiwan
National Taiwan University Hospital

Unknown

Sirolimus Blood Concentrations on Conversion From Oral Solution to Tablets

Kidney Transplantation | Immunosuppression | Transplantation

Taiwan
Eli Lilly and Company

Not yet recruiting

A Study to Compare Tablets and Capsules of Orforglipron (LY3502970) in Healthy Participants Who Are Obese or Overweight

Healthy | Obesity | Overweight | Obese

United States
Nanexa AB
Profil Institut für Stoffwechselforschung GmbH

Not yet recruiting

Phase 1 Study Assessing the Pharmacokinetics of NEX-22A in Subjects With T2D

Type 2 Diabetes
MediLink Therapeutics (Suzhou) Co., Ltd.

Not yet recruiting

A Phase 2 Study to Evaluate the Efficacy, Safety and Pharmacokinetics of YL202 in Patients With BC

Locally Advanced or Metastatic Breast Cancer

China
Daewoong Pharmaceutical Co. LTD.

Not yet recruiting

to Evaluate the Safety/Tolerability and Pharmacokinetics, and Pharmacodynamics of DWP14012 Injection

Erosive Gastroesophageal Reflux Disease
GlaxoSmithKline

Not yet recruiting

A Study to Compare the Pharmacokinetics (PK) of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152A (Test) or HFA-134A (Reference) in Healthy Participants Aged 18 to 55 Inclusive

Asthma | Healthy Participants

Netherlands
Rallybio IPA, LLC

Not yet recruiting

Phase 2 Study on the Pharmacokinetics and Safety of RLYB212 in Pregnant Women at Higher Risk for HPA-1a Alloimmunization

Fetal and Neonatal Alloimmune Thrombocytopenia
Innovative Molecules GmbH

Recruiting

Phase I Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single Doses of IM-250 in Healthy Volunteers

Herpes Simplex Virus

Germany
Atrogi AB

Recruiting

The Attractive 2 Trial - Pharmacokinetics of ATR-258 Oral Capsule vs. Oral Solution Formulations in Healthy Volunteers (Attractive 2)

Type2diabetes

Sweden
Ove Andersen
Mayo Clinic; University of Southern Denmark

Not yet recruiting

Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With Multimorbidity

Healthy | Multimorbidity
Celgene

Not yet recruiting

A Study to Evaluate the Drug Levels, Metabolism and Excretion, and Absolute Bioavailability of BMS-986365 in Healthy Male Participants

Healthy Volunteers

United States
Athira Pharma
Fortrea Holdings, Inc.

Recruiting

A SAD and MAD Study of the Safety, Tolerability, and Pharmacokinetics of ATH-1105

Healthy Volunteers

United States
Ionis Pharmaceuticals, Inc.

Not yet recruiting

ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)

Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome
GlaxoSmithKline

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 for Injection in Participants With Advanced Solid Tumors

Solid Tumors

United States, Canada, Australia
Pharmosa Biopharm Inc.
Novotech (New Zealand) Limited

Not yet recruiting

Safety, Tolerability and Pharmacokinetics Study of L608 in Healthy Adults

Pulmonary Arterial Hypertension

New Zealand
Gannex Pharma Co., Ltd.

Not yet recruiting

Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASC47 in Healthy Subjects

NASH
SpliSense Ltd.

Recruiting

Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients With Cystic Fibrosis

Cystic Fibrosis

United States
Imperial College London

Recruiting

Routinely Collected Clinical Data and Evaluation of Antimicrobial Target Attainment (DATATDM)

Pharmacokinetics | Drug-Related Side Effects and Adverse Reactions | Infections, Bacterial | Drug Monitoring

United Kingdom

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