Search clinical trials for: Phase I, Healthy Volunteers

Total 45700 results

Novartis Pharmaceuticals

Completed

A Phase 1 Study of Osilodrostat (LCI699) in Healthy Volunteers and Subjects With Impaired Hepatic Function

Hepatic Impairment

United States
Pfizer

Completed

A Study to Investigate the Effect of Administration of Ceftazidime-avibactam (CAZ-AVI) and Ceftaroline Fosamil -Avibactam (CXL) on the Intestinal Flora of Healthy Volunteers

Pharmacokinetics | Safety | Open Label | CAZ-AVI | CXL | Effect on Intestinal Flora

Sweden
AstraZeneca

Completed

Phase I Study to Assess the Effect on Healthy Male Volunteers of Ketoconazole on the Pharmacokinetics of a Single Dose of AZD5069 Administered Orally.

Asthma, | Pharmacokinetics, | Cmax, | Tmax, | λz, | AUC, | Ketoconazole, | Metabolite

United Kingdom
AstraZeneca

Completed

To Assess the Effect of Rifampicin on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers

Solid Tumours

United States
AstraZeneca

Terminated

Assess Safety, Tolerability and Pharmacokinetic (PK) of AZD1704 in Healthy Japanese Male and Non-Fertile Female Volunteers

Healthy Volunteers

United Kingdom
GE Healthcare
PPD; Fortrea

Not yet recruiting

A Phase 1, Dose-Escalation, Positron Emission Tomography Study to Assess the Safety, Pharmacokinetics, Dosimetry and Biodistribution of GEH200521 (18F) Injection Co-Administered With GEH200520 Injection in Healthy Volunteers

Healthy Volunteers

United States
Immunwork, Inc.

Not yet recruiting

A Phase 1 Study of TE-8214 Solution in Healthy Volunteers

Acromegaly

Australia
Pharmacobio

Recruiting

A Phase I Study of DDN-A-0101 in Healthy Volunteers and Elder People

Alzheimer Disease

Korea, Republic of
PMV Pharmaceuticals, Inc

Recruiting

A Study to Investigate the Effects of Itraconazole on the Pharmacokinetics of PC14586 in Healthy Participants

Healthy Volunteers

United States
Foresee Pharmaceuticals Co., Ltd.
InClin, Inc.

Not yet recruiting

Safety, Tolerability, and Pharmacokinetics, of Single and Multiple Ascending Doses of FP-020 in Healthy Adult Volunteers

Healthy

Australia
Bayer

Recruiting

A Study to Learn About How BAY2927088 Affects the Level of Dabigatran or Rosuvastatin in the Blood When These Drugs Are Taken Together in Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United Kingdom
Denali Therapeutics Inc.

Recruiting

A Phase 1, Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-DNL343 Following a Single Oral Dose in Healthy Male Participants

Healthy Volunteers

United States
S-Infinity Pharmaceuticals Co., Ltd

Not yet recruiting

A Phase I Study of XH-S003 in Healthy Volunteers

Healthy Adults

China
Neuracle Science Co., LTD.
Samsung Medical Center; Korea University Anam Hospital; Severance Hospital

Recruiting

A Phase 1b/2a, Study Evaluating the Safety, PK/PD and Efficacy of NS101 in Healthy Volunteers and SSNHL Patients

Sudden Sensorineural Hearing Loss | Seneorineural Deafness

Korea, Republic of
S-Infinity Pharmaceuticals Co., Ltd

Not yet recruiting

A Phase I Study of XH-S004 in Healthy Volunteers

Healthy Adults

China
Perha Pharmaceuticals
Fondation Jérôme Lejeune; European Innovation Council; France 2030 program

Recruiting

Leucettinib-21 First-in-Human Phase 1 in Healthy Volunteers and Subjects With Down Syndrome and Alzheimer's Disease (LEUCETTA)

Healthy Volunteers | Down Syndrome | Alzheimer's Disease

France
S-Infinity Pharmaceuticals Co., Ltd

Recruiting

A Phase I Study of XH-S002 in Healthy Volunteers

Healthy Adults

China
Almirall, S.A.

Recruiting

A Single and Multiple Ascending Dose Study of LAD603 in Healthy Subjects

Healthy Volunteers

United States
Diceros Therapeutics
Diceros Therapeutics Australia Pty Ltd

Not yet recruiting

Phase 1, SAD/MAD of Verasone™ Administered by Sinonasal Irrigation in Healthy Participants

Healthy Volunteers

Australia
National Institute of Allergy and Infectious Diseases...

Recruiting

Safety Study of SLV213 for the Treatment of COVID-19.

COVID-19

United States
ProMis Neurosciences, Inc

Recruiting

A Phase 1a Study of PMN310 In Healthy Volunteers

Healthy Participants

United States
Shanghai Leadingtac Pharmaceutical Co., Ltd.

Not yet recruiting

A Phase 1 Study of LT-002-158 Intended for the Treatment of Skind Disorder in Healthy Adult Volunteers

Atopic Dermatitis | Healthy Volunteer | Hidradenitis Suppurativa
Zhejiang Vimgreen Pharmaceuticals, Ltd.
Tigermed Consulting Co., Ltd

Recruiting

A Phase I Study of Single and Multiple Doses of VG290131 in Healthy Subjects

Healthy Volunteers

Australia
Vigonvita Life Sciences

Recruiting

Study of the Safety, Tolerability, and Pharmacokinetics of LV232 Capsules in Chinese Healthy Volunteers

Healthy Subjects

China
Nanjing RegeneCore Biotech Co., Ltd.

Recruiting

A Phase I Study of RC1416 Injection

Healthy Volunteers

China
Empros Pharma AB
CTC Clinical Trial Consultants AB

Recruiting

A Phase 1 Study to Evaluate EMP22 PD and EMP16 PK Versus Xenical® in Healthy Volunteers

Overweight or Obesity

Sweden
The Affiliated Hospital of Qingdao University

Recruiting

A Clinical Study of BG136 Injection in Healthy Chinese Volunteers

Healthy

China
MED-LIFE DISCOVERIES LP
BioPharma Services, Inc

Recruiting

A First-in-Human Phase 1 Study of Plasmalogen Precursor PPI-1011 in Healthy Adult Volunteers to Assess Safety, Tolerability, and Pharmacokinetics

Rhizomelic Chondrodysplasia Punctata

Canada
University of Tennessee Graduate School of Medicine
Attralus, Inc.

Recruiting

A Phase 1 Study of 99mTc-p5+14 in Healthy Volunteers and Patients With AL or ATTR Systemic Amyloidosis

Systemic Amyloidosis

United States
S-Infinity Pharmaceuticals Co., Ltd

Recruiting

A Phase 1 Study of XH-S003 in Healthy Volunteers

Healthy

Australia
Bill & Melinda Gates Medical Research Institute

Recruiting

Safety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults

Malaria

United States
Visirna Therapeutics HK Limited

Not yet recruiting

A VSA003 Phase 1 Study in Chinese Adult Healthy Volunteers

Dyslipidemias | Hypertriglyceridemia | Familial Hypercholesterolemia
Alnylam Pharmaceuticals

Recruiting

A Phase 1/2 Study to Evaluate ALN-KHK in Overweight to Obese Healthy Volunteers and Obese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)

Canada, United States
Brigham and Women's Hospital

Recruiting

First in Human Phase 1 Ascending Dose Study of PanChol in Healthy Volunteers

Cholera | Cholera Vaccine Toxicity

United States
Suzhou Ribo Life Science Co. Ltd.

Recruiting

A Single Ascending Doses Phase I Study to Evaluate the Safety and Pharmacokinetics of RBD4059 in Healthy Subjects

Healthy Volunteers

Australia
Nang Kuang Pharmaceutical Co., Ltd.

Recruiting

A Phase I Study to Evaluate the Safety and PK of ND-340 in Healthy Volunteers

Pain, Postoperative

Taiwan
Afasci Inc

Recruiting

Phase I Single Ascending Dose and Multiple Ascending Doses of Oral AFA-281 in Healthy Volunteers

Pain, Neuropathic | Pain, Inflammatory

United States
Godavari Biorefineries Limited

Not yet recruiting

Phase One Clinical Trial to Assess the Safety, Tolerability and Pharmacokinetics of MSP008-22 in Healthy Adult Volunteers

COVID-19

India
Pacira Pharmaceuticals, Inc

Recruiting

Phase 1, Dose Escalation Study to Evaluate of Safety, Pharmacokinetics and Pharmacodynamics of Liposomal Bupivacaine 13.3 Administered Via a Single Intrathecal Injection to Healthy Volunteers

Healthy

United States
University of Zurich

Recruiting

Safety and Tolerability of Chlorquine in Addition to Anti-tuberculosis Therapy

Tuberculosis Infection

Switzerland
Fujian Cosunter Pharmaceutical Co. Ltd

Recruiting

Phase I Study of GST-HG151 Tablets in Healthy Volunteers

Healthy Volunteers

China
Akeso

Not yet recruiting

A Phase I Clinical Trial of AK115 in Healthy Subjects

Healthy Volunteers
ProJenX
Worldwide Clinical Trials

Recruiting

A Study to Evaluate the Safety and Pharmacokinetics of Single and Multiple Doses of Prosetin in Healthy Volunteers (PRO-101)

Amyotrophic Lateral Sclerosis

United States
Viridian Therapeutics, Inc.

Recruiting

A Safety, Tolerability and Efficacy Study of VRDN 001 in Healthy Volunteers and Persons With Thyroid Eye Disease (TED)

Thyroid Eye Disease

Spain, United States, Netherlands, Germany, Canada, United Kingdom, Italy, Australia, France, Turkey
Prestige Biopharma Limited

Recruiting

To Compare the Pharmacokinetics and Safety of PBP1502 and Humira in Healthy Subjects

Healthy Volunteers

Spain
Moat Biotechnology Corporation
Moat Biotechnology Corporation

Recruiting

A Phase 1, First-In-Human Study of the Investigational COVID-19 Vaccine SC-Ad6-1 in Healthy Volunteers

Covid19

Australia
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co...

Recruiting

Phase 1 Study to Evaluate Safety and Pharmacokinetics of FZJ-003 in Healthy Volunteers

Healthy Volunteers

China
Aligos Therapeutics

Recruiting

A Study of ALG-000184 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single and Multiple Doses in Healthy Volunteers and CHB Subjects

Chronic Hepatitis B

Hong Kong, China, United Kingdom, Moldova, Republic of, New Zealand, Australia, Mauritius
Stephanie B. Seminara, MD

Recruiting

Evaluation of Kisspeptin Glucose-Stimulated Insulin Secretion With Physiologic Mixed Meal Tolerance

Pregnancy | Healthy Volunteers | Insulin | Glucose | Women

United States
Thomas Jefferson University
National Cancer Institute (NCI)

Recruiting

An Early Phase Study of Venetoclax, Lenalidomide, and Rituximab/Hyaluronidase in Slow-Growing Lymphomas That Have Come Back After Treatment or Have Not Responded to Treatment

Recurrent Marginal Zone Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Refractory Indolent Adult Non-Hodgkin Lymphoma | Recurrent Follicular Lymphoma | Refractory Follicular Lymphoma | Refractory Marginal Zone Lymphoma | Recurrent Indolent Adult Non-Hodgkin...

United States

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