Search clinical trials for: Pre-existing degeneration

Total 3938 results

Peking University Third Hospital

Recruiting

Paraspinal Muscle Degeneration, Bone Mass and Clinical Outcomes in Patients With Lumbar Degenerative Diseases

Degenerative Scoliosis | Degenerative Lumbar Spinal Stenosis

China
Peking University Third Hospital

Recruiting

Preventive Effect of Limited Decompression on Adjacent Segment Following Posterior Lumbar Interbody Fusion

Degenerative Disc Disease | Degenerative Lumbar Spinal Stenosis | Degeneration Spine

China
Peking University Third Hospital

Recruiting

Effect of Pre-existing Adjacent Segment Degeneration on Long-term Effectiveness After Lumbar Fusion Surgery

Degenerative Disc Disease | Degenerative Lumbar Spinal Stenosis | Degeneration Spine

China
Chengdu Origen Biotechnology Co., Ltd.

Not yet recruiting

Safety and Tolerability of KH658 Gene Therapy in Subjects With Neovascular Age-related Macular Degeneration (nAMD)

Age-related Macular Degeneration

China
PYC Therapeutics

Not yet recruiting

MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby)

Eye Diseases | Retinal Degeneration | Retinal Dystrophies | Retinal Disease | Retinitis Pigmentosa 11

United States
University of Maryland, Baltimore

Not yet recruiting

Effect of RECK in Posterior Spinal Fusion

Degenerative Disc Disease | Degenerative Spondylolisthesis | Degenerative Lumbar Spinal Stenosis | Degenerative Disease

United States
Ascidian Therapeutics, Inc

Recruiting

Prescreening Study to Identify Potential Participants for ACDN-01 Clinical Trials

Stargardt Disease | Stargardt Disease 1 | Juvenile Macular Degeneration | Cone Rod Dystrophy

United States
Hoffmann-La Roche
Shanghai Roche Pharmaceutical Co., Ltd

Recruiting

Real World Evidence in China: Faricimab Use in Diabetic Macular Edema, Retinal Vein Occlusion, and Neovascular Age-Related Macular Degeneration (The Farseeing Study)

Diabetic Macular Edema | Retinal Vein Occlusion | Neovascular Age-related Macular Degeneration

China
Splice Bio

Recruiting

An Observational Study in Subjects to Follow the Progression of Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic Autosomal Recessive Mutations in the ABCA4 Gene (POLARIS)

Stargardt Disease | Stargardt's Disease | STGD1 | Stargardt
Hospices Civils de Lyon

Not yet recruiting

Circadian Variation of Urinary Copper Excretion in Wilson Disease Patients (VARCUWIC)

Wilson Disease

France
Zhejiang University

Not yet recruiting

Comparing Artificial Intelligence for Assisted Diagnosis of Diabetic Retinopathy

Diabetic Retinopathy | Diabetic Macular Edema

China
Bayer
Regeneron Pharmaceuticals

Recruiting

A Study to Learn More About How Well 8 Milligram Aflibercept Works and How Safe it is in Chinese Participants With Diabetic Macular Edema (PHOTONiC)

Diabetic Macular Edema

China, Hong Kong
Synergy Spine Solutions
MCRA

Not yet recruiting

Post-Market Data Collection Protocol to Evaluate the Performance of the Synergy Disc®

Cervical Degenerative Disc Disease

United Kingdom
Samsung Medical Center

Recruiting

Maternal and Offspring Outcomes in Pregnant Women With Pre-existing ASCVD (CVD_OBS)

Cardiovascular Diseases | Atherosclerosis | Pregnancy Complications | Adverse Cardiac Event | Adverse Birth Outcomes

Korea, Republic of
Yale University

Not yet recruiting

Evaluating the Efficacy of a Mobile Application in Postoperative Rehabilitation

Knee Osteoarthritis | Hip Fractures | Spine Degeneration | Hip Arthritis
Regeneron Pharmaceuticals

Not yet recruiting

An Observational Study to Investigate the Use of Aflibercept 8 mg to Treat Adult Patients With Neovascular Age-Related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) in a Real-World Setting (SPECTRUM-US)

Visual Impairment | Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (nAMD) | Wet Age-related Macular Degeneration (AMD)
Steminent US, Inc.

Not yet recruiting

Stemchymal® for Polyglutamine Spinocerebellar Ataxia

Spinocerebellar Ataxias
Eyestem Research Pvt. Ltd.

Recruiting

Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration.

Eye Diseases | Age-Related Macular Degeneration | Macular Degeneration | Geographic Atrophy | Retinal Disease

India
The Methodist Hospital Research Institute

Recruiting

IL-2 Plus Abatacept in FTD

Frontotemporal Degeneration

United States
Ocugen

Recruiting

A Phase 3 Study Of OCU400 Gene Therapy for the Treatment Of Retinitis Pigmentosa (liMeliGhT)

Retinitis Pigmentosa

United States
Belite Bio, Inc

Not yet recruiting

A Phase 2/3 Study to Evaluate the Efficacy and Safety of Tinlarebant in Subjects With Stargardt Disease (DRAGON II)

Stargardt Disease 1 | STGD1

United States
Synergy Spine Solutions
MCRA

Recruiting

Real World Data Collection on the Synergy Disc

Cervical Degenerative Disc Disease

Ireland
Synergy Spine Solutions
MCRA

Not yet recruiting

Post-Market Data Collection to Evaluate the Performance of the Synergy Disc®

Cervical Degenerative Disc Disease

United Kingdom
University of Wisconsin, Madison

Recruiting

Retinal Fundus Flavoprotein Fluorescence in Age Related Macular Degeneration (FPF in AMD)

Age-Related Macular Degeneration | Geographic Atrophy

United States
University of Pennsylvania

Not yet recruiting

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

Parkinson Disease | Alzheimer Disease | ALS | Polyneuropathies | Frontotemporal Dementia | Pheochromocytoma | Thoracic Aortic Aneurysm | Paraganglioma | Genetic Predisposition | Cardiomyopathy Non-ischemic
Ray Therapeutics, Inc.
The Vision Research and Assessment Institute (VRAI)

Recruiting

Observational Study to Assess Endpoint Operational Feasibility & Measurement Properties in Retinitis Pigmentosa Patients

Retinitis Pigmentosa

United States
Stealth BioTherapeutics Inc.

Recruiting

ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degeneration (Dry AMD) (ReNEW)

Age-Related Macular Degeneration

United States
Peking University Third Hospital

Recruiting

Effect of Early Gait Training on Knee Cartilage Degeneration After Anterior Cruciate Ligament Reconstruction

Anterior Cruciate Ligament Injuries | Cartilage Degeneration

China
Potsawat Surabotsopon

Not yet recruiting

Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF : Double Blinded, Randomized Control Trial (MIS-TLIF)

Surgery | Disc Degeneration | Spinal Stenosis Lumbar | Fusion of Spine | Disc Disease
Chang Gung University

Recruiting

Electrical Stimulation Cycling Training Effects on SCA

Spinocerebellar Ataxia (SCA)

Taiwan
Universidade Nova de Lisboa
iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM,... and other collaborators

Recruiting

Intermediate Age-related Macular Degeneration - Multimodal Analysis and Longitudinal Study (Imaging4iAMD)

Age-Related Macular Degeneration

Portugal
Medical University of Vienna
University of Zurich; Centre Hospitalier Universitaire Dijon; Fundacion Clinic... and other collaborators

Not yet recruiting

Personalized Monitoring of Non-foveal, Non-vision Compromising Atrophic Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression (APENNINES)

Age-Related Macular Degeneration | Geographic Atrophy
LumiThera, Inc.

Recruiting

A Registry Study to Assess Photobiomodulation in Dry Age-Related Macular Degeneration (EUROLIGHT) (EUROLIGHT)

Dry Age-related Macular Degeneration

Norway
Medical University of Vienna
University of Zurich; Centre Hospitalier Universitaire Dijon; Fundacion Clinic... and other collaborators

Not yet recruiting

Personalised Monitoring of Early and Intermediate Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression (SUDETES)

Age-Related Macular Degeneration
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

Identification of Biomarkers and Molecular Targets Involved on Intervertebral Disc Degeneration and Discogenic Pain

Intervertebral Disc Degeneration | Discogenic Pain | Discogenic Disease

Italy
National University of Singapore
California Table Grape Commission

Not yet recruiting

Impact of Grape Powder Consumption on Eye Health and Glycemic Status in Singapore Older Adults

Aging | Macula; Degeneration | Advanced Glycation End Products
Universitaire Ziekenhuizen KU Leuven
DORC Dutch Ophthalmic Research Center International BV

Recruiting

Robotic Subretinal tPA Injection Study (RoTIS)

Age-Related Macular Degeneration | Subretinal Hemorrhage

Belgium
Skyline Therapeutics

Recruiting

A Long-term Follow-up Study to Evaluate SKG0106 in the Treatment of Patients With nAMD

Neovascular (Wet) Age-related Macular Degeneration

China, United States
West China Hospital

Recruiting

Safety and Efficacy of a Single Subretinal Injection of JWK002 Gene Therapy in Subjects With X-linked Retinoschisis(XLRS)

X Linked Retinoschisis

China
SpineVision
Slb Pharma

Recruiting

Safety and Performance of the SpineVision Posterior Fixation Systems in Thoracolumbar Spinal Treatment (FixedD3)

Intervertebral Disc Degeneration

France
University Hospital, Lille
France Alzheimer

Not yet recruiting

Social & Affective Cognition in Alzheimer's Disease & Associated Disorders (SOCIALIZE)

Alzheimer's Disease | Frontotemporal Degeneration (Semantic & Behavioral Variants)
Istituto Auxologico Italiano

Recruiting

Advances in Telephone-based Cognitive Screening Procedures (TBCS)

Cerebrovascular Disorders | Amyotrophic Lateral Sclerosis | Frontotemporal Degeneration | Alzheimer's Disease | Lewy Body Dementia

Italy
Centre Hospitalier National d'Ophtalmologie des...

Not yet recruiting

Impact of Age-related Macular Degeneration on Daily Living Activitie (AMDAY)

Age-Related Macular Degeneration
IRCCS Multimedica
AbbVie

Recruiting

OCT and OCT-Angiography Biomarkers of Treatment Response to Dexamethasone Implant in Macular Edema Due to Retinal Vascular Diseases - DME and RVO

Diabetic Macular Edema | Retinal Vein Occlusion | Macular Edema Due to Diabetes Mellitus

Italy
Mesoblast, Ltd.

Not yet recruiting

Efficacy and Safety of Rexlemestrocel-L Combined With HA* in Participants With Moderate to Severe Chronic Low Back Pain (HyaluronicAcid)

Degenerative Disc Disease
University Hospital Tuebingen

Recruiting

Natural History Study in Patients With PDE6A-, PDE6B- and RHO-linked Retinitis Pigmentosa

Retinitis Pigmentosa

Germany
University of Rochester

Not yet recruiting

The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration

Age-Related Macular Degeneration | Retinitis Pigmentosa | Retinal Dystrophies | Alcohol Use Disorder | Stargardt Disease

United States
Rehab Azzam

Not yet recruiting

Outcomes After Vitrectomy in Eyes With Tractional Diabetic Macular Edema

Diabetic Macular Edema
Everads Therapy

Recruiting

Everads Injector in Suprachoroidal Administration of TA Suspension, for Treatment of Patients With DME

Diabetic Macular Edema

Israel
Shanghai Eye Disease Prevention and Treatment Center
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Recruiting

Efficacy and Safety of Conbercept for Diabetic Macular Edema Combined With Severe Non-proliferative Diabetic Retinopathy

Diabetic Macular Edema

China

Search clinical trials for: Pre-existing degeneration

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