Search clinical trials for: Primary Immunodeficiency Syndrome

Total 51582 results

Emory University

Completed

Bone Marrow Transplant With Abatacept for Non-Malignant Diseases

Sickle Cell Disease | Fanconi Anemia | Hurler Syndrome | Chronic Granulomatous Disease | Severe Congenital Neutropenia | Hemophagocytic Lymphohistiocytosis | Wiskott-Aldrich Syndrome | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Glanzmann Thrombasthenia | Shwachman-Diamond Syndrome | Thalassemia Major | Leukocyte... and other conditions

United States
National Human Genome Research Institute (NHGRI)

Withdrawn

Quality of Life and Neuropsychiatric Sequelae in Patients Treated With Gene Therapy for ADA-SCID and in Their Parents

ADA-SCID
National Human Genome Research Institute (NHGRI)

Completed

Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency

Severe Combined Immunodeficiency Syndrome

United States
National Institute of Allergy and Infectious Diseases...

Unknown

Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age With X-Linked Severe Combined Immunodeficiency (LVXSCID-OC)

X-Linked Combined Immunodeficiency Diseases

United States
Children's Hospital Medical Center, Cincinnati
Hoxworth Blood Center

Terminated

CD34+ Stem Cell Infusion to Augment Graft Function

Bone Marrow Failure | Waning Donor Chimerism | Waning Immune Function | Primary Immunodeficiency Disease(s)

United States
Institut de Médecine et d'Epidémiologie Appliquée...

Completed

Kinetics of HIV-RNA Decay in Seminal Plasma of Men Treated by Dolutegravir at the Time of Primary HIV Infection (DOLUPRIM)

HIV Infection Primary
University of California, San Diego
National Institutes of Health (NIH); Centers for Disease Control and Prevention

Completed

Implementation of Nucleic Acid Amplification Testing Screening to Identify Acute and Early HIV Infection

Acute HIV Infection

United States
Grifols Therapeutics LLC

Completed

Safety and Pharmacokinetics of IGSC 20% in Subjects With Primary Immunodeficiency

Primary Immunodeficiency

United States, Canada
Unity Health Toronto

Unknown

Using Electronic Medical Record Data to Improve HIV Primary Care

HIV/AIDS | Electronic Health Records | Quality of Health Care

Canada
Roswell Park Cancer Institute

Completed

Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Primary Myelofibrosis | Polycythemia Vera | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma and other conditions

United States
Shenzhen Geno-Immune Medical Institute

Unknown

Gene Transfer for ADA-SCID Using an Improved Lentiviral Vector (TYF-ADA)

Adenosine DeAminase Severe Combined ImmunoDeficiency (ADA-SCID)

China
Shenzhen Geno-Immune Medical Institute

Unknown

Gene Transfer for SCID-X1 Using a Self-inactivating Lentiviral Vector （TYF-IL-2Rg）

SCID, X Linked

China
Kuwait Society for Allergy and Clinical Immunology

Completed

Primary Immunodeficiency in Kuwait

Primary Immune Deficiency Disorder

Kuwait
MUC Research GmbH
Merck Sharp & Dohme LLC; Pfizer; AbbVie; German Center for Infection Research

Completed

New Era Study: Treatment With Multi Drug Class (MDC) HAART in HIV Infected Patients (NewEra)

HIV Infections

Germany
BriovaRx Infusion Services
Bio Products Laboratory (BPL)

Completed

Monitoring of 5% Treatment Naïve Intravenous Immunoglobulin (IVIg) Primary Immunodeficiency Disease (PIDD) Patients Using the CareExchange® System: A Pilot Study Using 5% Gammaplex® IVIg in the Home Setting

Primary Immunodeficiency Disease (PIDD)

United States
BriovaRx Infusion Services

Terminated

Gamma Globulin Observations and Outcomes Database for Patients With Primary Immunodeficiency Disease (GOOD-SHEPARD-PI)

Primary Immune Deficiency Disorder

United States
University of Arkansas

Withdrawn

Pancreatic Cancer Screening of High-Risk Individuals in Arkansas

Pancreatic Neoplasms | Colorectal Neoplasms, Hereditary Nonpolyposis | BRCA1 Gene Mutation | BRCA2 Gene Mutation | Hereditary Pancreatitis | Ataxia Telangiectasia | Peutz-Jegher's Syndrome | Familial Atypical Mole-Malignant Melanoma Syndrome

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Total-Body Irradiation Followed By Cyclosporine and Mycophenolate Mofetil in Treating Patients With Severe Combined Immunodeficiency Undergoing Donor Bone Marrow Transplant

Severe Combined Immunodeficiency | Adenosine Deaminase Deficiency | Immune System Disorder | Autosomal Recessive Disorder | Purine-Nucleoside Phosphorylase Deficiency | Severe Combined Immunodeficiency With Absence of T and B Cells | X-Linked Severe Combined Immunodeficiency

United States
University Hospital, Lille
Shire

Completed

IgG Level in Primary Immunodeficiency Switching From Standard SCIG to Every Other Week HyQvia

Primary Immunodeficiency

France
Octapharma

Completed

Octagam 5% Versus Comparator Post Marketing Trial

Primary Immune Deficiency Disorder

United States
Rockefeller University

Terminated

Viral and Host Factors in the Transmission and Pathogenesis of HIV

HIV Infections

United States
Octapharma

Completed

A Study to Compare Quality of Life and Satisfaction in Primary Immunodeficient Patients Treated With Subcutaneous Injections of Gammanorm® 165 mg/mL Administered With Two Different Delivery Devices: Injections Using Pump or Rapid Push

Primary Immunodeficiency

United Kingdom, Australia, Germany, Italy
CHU de Reims

Unknown

Tolerance and Patients' Satisfaction With IGHy

Secondary or Primary Immunodeficiency

France
Johns Hopkins University

Terminated

Cell-Based Approaches For Modeling and Treating Ataxia-Telangiectasia

Ataxia-Telangiectasia (A-T)

United States
Weill Medical College of Cornell University
Novartis Pharmaceuticals

Terminated

Thrombocytopenia and Bleeding in Wiskott-Aldrich Syndrome (WAS) Patients (WAS)

Bleeding | Thrombocytopenia | Wiskott-Aldrich Syndrome

United States
GlaxoSmithKline

Completed

Targeted Literature Review and Subject Interviews in Wiskott-Aldrich Syndrome (WAS)

Wiskott-Aldrich Syndrome

United States
Orpha Labs

Completed

Study of ORL-1F (L-fucose) in Patients With Leukocyte Adhesion Deficiency Type II

Leukocyte Adhesion Deficiency, Type II
Boston University
National Institute of Allergy and Infectious Diseases (NIAID); University of...

Completed

Rapid Initiation of Antiretroviral Therapy to Promote Early HIV/AIDS Treatment in South Africa (RapIT Study) (RapIT)

HIV

South Africa
Federal Research Institute of Pediatric Hematology...

Unknown

A Trial of Plerixafor/G-CSF as Additional Agents for Conditioning Before TCR Alpha/Beta Depleted HSCT in WAS Patients

Hematopoietic Stem Cell Transplantation | Wiskott-Aldrich Syndrome | Graft Failure

Russian Federation
X4 Pharmaceuticals

Withdrawn

A Retrospective and Prospective Natural History Study of Patients With WHIM Syndrome

WHIM Syndrome
University Hospital, Caen

Unknown

ENCAPSID Study : ENCApsulated Bacterial Infection and Primary, Secondary ImmunoDeficiency (ENCAPSID)

Immune Deficiency

France
CSL Behring

Completed

A Study to Evaluate the Long-term Clinical Safety and Efficacy of Subcutaneously Administered C1-esterase Inhibitor in the Prevention of Hereditary Angioedema

Hereditary Angioedema Types I and II

United States, Spain, Germany, Australia, Canada, Czechia, Hungary, Israel, Italy, Romania, United Kingdom
Fondation Ophtalmologique Adolphe de Rothschild

Terminated

Genetic Factors of Idiopathic Polypoidal Vasculopathies in the ATM Gene (Ataxia Telangiectasia Mutated) (ATM)

Choroidal Neovascularization

France
University of California, San Francisco
Kaiser Foundation Research Institute

Completed

Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients

Substance-Related Disorders | Acquired Immunodeficiency Syndrome | Alcoholism | HIV | Alcoholic Intoxication

United States
Bio Products Laboratory

Completed

Pharmacokinetics (PK) and Safety of Subgam-VF in Primary Immunodeficiency Diseases (SCIG03)

Common Variable Immunodeficiency | Primary Immune Deficiency Disorders | X-linked Agammaglobulinaemia | Hyperimmunoglobulin M Syndrome

United States
Stockton University
Nova Southeastern University

Completed

The Impact of Exercise on Stress, Fatigue, and Quality of Life in Individuals With Primary Immunodeficiency Disease

Common Variable Immunodeficiency | Hypergammaglobulinemia | Primary Immune Deficiency Disorder | Specific Antibody Deficiency

United States
Octapharma

Completed

Gammanorm Quality of Life Study in Immunodeficient Patients Using Rapid Push or Pumps

Primary Immunodeficiency (PID)

France
University of California, San Francisco

Terminated

Hematopoietic Stem Cell Transplantation (HSCT) for Children With SCID Utilizing Alemtuzumab, Plerixafor & Filgrastim

Severe Combined Immunodeficiency

United States
Nantes University Hospital

Completed

Generalized Neonatal Screening of Severe Combined Immunodeficiencies (DEPISTREC)

Severe Combined Immunodeficiency, Atypical

France
Pharming Technologies B.V.

Completed

A Study of the Safety and Immunogenicity of Repeated rhC1INH Administration (OPERA)

Hereditary Angioedema | Genetic Disorders

Netherlands, Romania
Genethon
Hôpital Necker-Enfants Malades

Completed

Gene Therapy for WAS

Wiskott-Aldrich Syndrome

France
Imagine Institute
Assistance Publique - Hôpitaux de Paris

Completed

Evaluation of the Efficacy of the Sequencing Method by Gene-panel (Génétique-DIH)

Primary Immuno-Deficiencies

France
CSL Behring

Completed

Study of Immune Deficiency Patients Treated With Subcutaneous Immunoglobulin (IgPro20, Hizentra®) on Weekly and Biweekly Schedules

Primary Immune Deficiency | Secondary Immune Deficiency

Canada
Bio Products Laboratory

Completed

A Multi-centre Open Study to Assess the Safety and Efficacy of Subgam®

Primary Antibody Deficiency

United Kingdom
Masonic Cancer Center, University of Minnesota

Terminated

T-Cell Depletion and Stem Cell Transplant for Immune Deficiencies and Histiocytic Disorders

Hematologic Diseases | Hemophagocytic Lymphohistiocytosis | Immunologic Diseases | Chediak-Higashi Syndrome | X-Linked Lymphoproliferative Disorders | Griscelli Syndrome | Langerhans-Cell Histiocytosis

United States
Beijing Children's Hospital
Shenzhen Children's Hospital; Capital Institute of Pediatrics, China

Unknown

Pediatric Primary Immunodeficiency Disease (PID) in China

Primary Immunodeficiency Disease
Masonic Cancer Center, University of Minnesota

Completed

Stem Cell Transplant for Immunologic or Histiocytic Disorders

Immunologic Deficiency Syndromes | Hemophagocytic Lymphohistiocytosis | Chediak-Higashi Syndrome | X-Linked Lymphoproliferative Disorders | Griscelli Syndrome | Langerhans-Cell Histiocytosis

United States
Johns Hopkins University

Completed

Baclofen Treatment of Ataxia Telangiectasia

Ataxia Telangiectasia

United States
Pharming Technologies B.V.

Completed

A Phase 2 HAE Prophylaxis Study With Recombinant Human C1 Inhibitor

Hereditary Angioedema

United States, Canada, Czechia, Italy, Macedonia, The Former Yugoslav Republic of, Romania, Serbia
NHS Tayside
University of Dundee

Completed

Response of Individuals With Ataxia-Telangiectasia to Metformin and Pioglitazone (RAMP)

Ataxia-Telangiectasia

United Kingdom

Search clinical trials for: Primary Immunodeficiency Syndrome

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Argentina

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations