Search clinical trials for: Proof of Concept Study

Total 441377 results

Benha University

Recruiting

Articaine Plus Dexmedetomidine in Supraclavicular Block

Post Operative Pain, Acute

Egypt
Indivior Inc.

Not yet recruiting

Proof of Concept and Dose-ranging Study of INDV-2000 in Individuals With Moderate to Severe Opioid Use Disorder

Opioid Use Disorder
Qiong Fu

Not yet recruiting

A Prospective, Single Arm, Open Label, Proof of Concept Clinical Study of Sulfasalazine in the Treatment of Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Universiteit Antwerpen
McGill University; Aragon Institute of Health Sciences

Not yet recruiting

Comparative Study of the Mechanism of Action of Dry Needling and Botulinum Toxin Type A as a Treatment for Lower Limb Post-stroke Spasticity: a Proof of Concept Controlled Trial (STROKEPOC)

Stroke | Spasticity as Sequela of Stroke
Sanofi
Regeneron Pharmaceuticals

Recruiting

A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Non-cystic Fibrosis Bronchiectasis

Bronchiectasis

United Kingdom, Israel, Japan, United States, Canada, Chile
Dartmouth-Hitchcock Medical Center
National Cancer Institute (NCI)

Recruiting

A Randomized Two-Arm Proof of Concept Study Testing A Novel Approach to Exercise Promotion Based on Affect-regulation

Breast Cancer

United States
Fudan University
Shanghai Weihe Medical Laboratory Co., Ltd.

Recruiting

Liquid Biopsy-based Early Detection of Ovarian Cancer: a Proof-of-concept Study ( PROFOUND-OC )

Ovarian Cancer

China
McMaster University
Center for Medicinal Cannabis Research

Not yet recruiting

Psilocybin in the Treatment of Cannabis Use Disorder: A-Proof-of-Concept Study (PSI_CUD)

Cannabis Use Disorder, Moderate | Cannabis Use Disorder, Severe
National Taiwan University Hospital

Recruiting

A Proof-of-concept Study Evaluating the Microbiota-gut-brain Axis

Parkinson Disease

Taiwan
University of North Carolina, Chapel Hill
Eli Lilly and Company

Recruiting

Efficacy and Safety of Baricitinib in Oral Lichen Planus: a Proof-of-Concept Study

Lichen Planus, Oral | Oral Lichen Planus | Lichen Planus, Mucosal

United States
Emory University
National Center for Advancing Translational Sciences (NCATS)

Not yet recruiting

HIIT: A Proof-of-Concept Study

Obesity
Novartis Pharmaceuticals

Recruiting

A Proof of Concept and Dose-finding Study of XXB750 in Patients With Heart Failure

Heart Failure

Italy, Spain, United States, Japan, China, Germany, Taiwan, Bulgaria, Denmark, France, Portugal, Slovakia
Regeneron Pharmaceuticals

Not yet recruiting

A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma (LINKER-MGUS1)

Monoclonal Gammopathy of Undetermined Significance (MGUS) | Smoldering Multiple Myeloma (SMM)
Sanofi

Recruiting

Proof-of-concept Study Evaluating Subcutaneous Amlitelimab in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis

Chile, Canada, Spain, United States, Australia, Portugal, Hungary, Italy, Germany
Foundation for Innovative New Diagnostics, Switzerland
Kenya Medical Research Institute

Not yet recruiting

Leishmania Antigen Rapid Diagnostic Test Proof-of-Concept and Validation Study

Visceral Leishmaniasis
Fondazione Don Carlo Gnocchi Onlus
IRCCS Centro Neurolesi "Bonino-Pulejo"; University of Milano Bicocca; IRCCS Centro...

Not yet recruiting

The DANCEREX Proof-of-Concept Study for Chronic Neurological Disorders (DANCEREX-DTx)

Neurocognitive Dysfunction | Sclerosis, Multiple | Neurocognitive Impairment, Mild
Massachusetts Eye Research and Surgery Institution
Eli Lilly and Company

Recruiting

Ixekizumab for the Management of Refractory Non-Infectious Uveitis: A Proof-of-Concept Study

Uveitis, Anterior | Panuveitis | Uveitis, Posterior | Uveitis, Intermediate

United States
Vitti Labs, LLC

Recruiting

A Proof of Concept Study to Evaluate Exosomes From Human Mesenchymal Stem Cells in Women With Premature Ovarian Insufficiency (POI) (VL-POI-01)

Diminished Ovarian Reserve | Premature Ovarian Insufficiency

United States
ViiV Healthcare

Recruiting

Proof of Concept Treatment Study of Orally Administered VH4004280 or VH4011499 in HIV-1 Infected Adults (CINNAMON)

HIV Infections

United States, France, Italy, Spain, Germany, Canada, Mexico, Argentina, United Kingdom
Stanford University

Not yet recruiting

Vibrotactile Coordinated Reset in Parkinson's Disease - Proof of Concept Study

Parkinson Disease

United States
Tri.O Medical LTD

Recruiting

Proof of Concept Open Label, Clinical Trial to Evaluate the Safety and Efficacy of the "FITT" Device in Diabetic Foot Ulcers Patients (TriO FITT)

Diabetic Foot Ulcer

Israel
University of Louisville

Recruiting

Can Rumination-Focused Cognitive Behavioral Therapy Reduce the Risk of Cardio-vascular Disease? (RFCBT-I)

Blood Pressure | Depressive Symptoms | Rumination

United States
Drugs for Neglected Diseases
Novartis Pharmaceuticals

Recruiting

LXE408 for Treatment of Visceral Leishmaniasis in Ethiopia, a Proof of Concept Study

Primary Visceral Leishmaniasis

Ethiopia
Regeneron Pharmaceuticals

Recruiting

A Proof-of-Concept Trial to Study the Safety and Activity of Linvoseltamab in Participants With Smoldering Multiple Myeloma at High Risk of Developing Multiple Myeloma

Smoldering Multiple Myeloma (SMM)

Spain
Bioprojet

Not yet recruiting

Proof of Concept Study on Pitolisant Effect on Autism Spectrum Disorders in Children and Adolescents

Autism Spectrum Disorder
University of Calgary

Recruiting

CO2 Rebreathing in nOH: A Proof-of-Concept Pilot Study

Neurogenic Orthostatic Hypotension | Autonomic Failure

Canada
Immunovant Sciences GmbH

Recruiting

A Proof-of-Concept Study to Assess Batoclimab in Participants With Graves' Disease

Graves Disease

Germany
Universitätsklinikum Hamburg-Eppendorf
Lithuanian University of Health Sciences; Örebro University, Sweden; University... and other collaborators

Recruiting

Proof of Concept Human Study: Dietary Intervention to Modify Intestinal Inflammation in IBD

Reduction of Intestinal Inflammatory Activity

Germany
Aneira Pharma, Inc.

Recruiting

Proof of Concept Study of Latanoprost/Minoxidil (ANR-001.1) Topical Formulation

Hypotrichosis

United States
University of Michigan Rogel Cancer Center
Genentech, Inc.

Not yet recruiting

A Proof of Concept Pilot Study of the Addition of Venetoclax to Standard Remission Induction Chemotherapy Fludarabine or Cladrabine, Cytarabine, and Granulocyte Colony Stimulating Factor (G-CSF) (FLAG or CLAG) for Frontline Therapy of Secondary Acute Myeloid Leukemia

Secondary Acute Myeloid Leukemia

United States
Mira Zuidgeest
Sanofi; Innovative Medicines Initiative; IMI Trials@Home consortium

Recruiting

Remote And Decentralised Innovative Approaches to Clinical Trials (RADIAL) (RADIAL)

Diabetes Mellitus, Type 2

United Kingdom, Denmark, Germany
Leiden University Medical Center
University Medical Center Groningen; Erasmus Medical Center

Not yet recruiting

Neo-adjuvant Pembrolizumab in Vulvar Squamous Cell Carcinoma: a Clinical Proof-of-concept Study (Apollo)

Squamous Cell Cancer | Vulva Cancer | Vulva Neoplasm
Artax Biopharma Inc

Recruiting

Proof of Concept Study of AX-158 in Patients With Mild to Moderate Plaque Psoriasis

Psoriasis | Plaque Psoriasis

United Kingdom
Austin Institute for Clinical Research

Recruiting

Proof of Concept Study to Access Superficial Basal Cell Carcinoma in Adults

Superficial Basal Cell Carcinoma

United States
Hera Biotech, Inc.

Recruiting

Proof of Concept Study to Eval MetriDx Lab-developed Test to Identify Endometriosis-specific Bio Markers

Endometriosis | Diagnosis

United States
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

Phase IIa Proof of Concept Study of M5717-Pyronaridine in Adults and Adolescents With Acute Uncomplicated Plasmodium Falciparum Malaria (CAPTURE 1)

Acute Malaria

Burkina Faso, Gabon, Mozambique, Uganda
Amgen

Recruiting

A Phase 2 Proof of Concept Study to Evaluate the Efficacy and Safety of Daxdilimab in Participants With Dermatomyositis (DM) or Anti-synthetase Inflammatory Myositis (ASIM)

Idiopathic Inflammatory Myositis

Germany, Australia, Brazil, United States, Mexico, Italy
Centre Hospitalier Universitaire de Nīmes

Recruiting

Proof-of-concept Study of Blood Markers of Tumor Dissemination in Patients With Versus Without Intestinal Polyps (EARDIS)

Neoplasm Metastasis | Colorectal Cancer | Disseminated Cancer

France
Changi General Hospital
KK Women's and Children's Hospital (KKH)

Not yet recruiting

Developing a Virtual Reality (VR)-Based Prototype for Perioperative Care - a Proof of Concept Study

Postoperative Pain | Anxiety | Pain, Acute

Singapore
Johnson & Johnson Surgical Vision, Inc.

Recruiting

PROOF-OF-CONCEPT STUDY FOR NEW INTRAOCULAR LENS, MODEL C0002

Cataracts

France
University Hospital, Geneva

Not yet recruiting

Dynamic Response to Probiotics in Context of Alzheimer Disease: a Proof-of-concept Study (HISTEPPA)

Alzheimer Disease
Kira Pharmacenticals (US), LLC.

Not yet recruiting

Study to Evaluate Safety, Tolerability and Pharmacodynamics of KP104 in Participants With Thrombotic Microangiopathy Secondary to Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
COMPASS Pathways

Recruiting

Efficacy and Safety of COMP360 Psilocybin Therapy in Anorexia Nervosa: a Proof-of-concept Study

Anorexia Nervosa

Ireland, United States, United Kingdom
Novartis Pharmaceuticals

Recruiting

A Proof-of-concept Study to Examine QUC398 in Participants With Knee OA

Osteoarthritis, Knee

Spain, United States, Denmark, France, Australia, Norway
Alzeca Biosciences, Inc.
pharmtrace klinische Entwicklung GmbH

Recruiting

Proof-of-concept Study of New Imaging Diagnostic in Patients With Suspected Alzheimer's Disease

Alzheimer Disease

Germany
Natural Immune Systems Inc

Recruiting

Clinical Proof-of-concept Study on Immune Surveillance and Alertness

Immune Surveillance

United States
Clinical Academic Center (2CA-Braga)

Not yet recruiting

Proof-of-concept Study to Evaluate the Safety and Efficacy of Tryptophan in Patients With BPH. (TryptoBPH)

BPH
Natural Immune Systems Inc

Recruiting

Clinical Proof-of-concept Study on Rapid Immune Modulating Effects

Immune Surveillance

United States
Fundacin Biomedica Galicia Sur
Germans Trias i Pujol Hospital; Hospital del Mar; Hospital Universitario 12 de... and other collaborators

Recruiting

Precision Medicine in LN: A Multicenter Proof-of-concept Study for Histopathological Biomarkers Analysis in Renal Biopsy

Systemic Lupus Erythematosus | Lupus Nephritis

Spain
Medical University of Graz

Not yet recruiting

Impact of Hepatitis B Immunoglobulins in Patients With Chronic Hepatitis B on Hepatocellular Carcinoma - a Proof of Concept Study (HBIG)

Hepatocellular Carcinoma | HBV

Search clinical trials for: Proof of Concept Study

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Burundi

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations