Search clinical trials for: Proof-of-concept study

Total 118793 results

Benha University

Recruiting

Articaine Plus Dexmedetomidine in Supraclavicular Block

Post Operative Pain, Acute

Egypt
Sanofi

Recruiting

Proof-of-concept Study Evaluating Subcutaneous Amlitelimab in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis

Chile, Canada, Spain, United States, Australia, Portugal, Hungary, Italy, Germany
University of Louisville

Recruiting

Can Rumination-Focused Cognitive Behavioral Therapy Reduce the Risk of Cardio-vascular Disease? (RFCBT-I)

Blood Pressure | Depressive Symptoms | Rumination

United States
Centre Hospitalier Universitaire de Nīmes

Recruiting

Proof-of-concept Study of Blood Markers of Tumor Dissemination in Patients With Versus Without Intestinal Polyps (EARDIS)

Neoplasm Metastasis | Colorectal Cancer | Disseminated Cancer

France
Alzeca Biosciences, Inc.
pharmtrace klinische Entwicklung GmbH

Recruiting

Proof-of-concept Study of New Imaging Diagnostic in Patients With Suspected Alzheimer's Disease

Alzheimer Disease

Germany
Clinical Academic Center (2CA-Braga)

Not yet recruiting

Proof-of-concept Study to Evaluate the Safety and Efficacy of Tryptophan in Patients With BPH. (TryptoBPH)

BPH
McMaster University
GlaxoSmithKline; University of Manchester

Recruiting

Mepolizumab for the Treatment of Chronic Cough With Eosinophilic Airways Diseases (MUCOSA)

Asthma | Eosinophilic Bronchitis | Chronic Cough

Canada
Imperial College London

Recruiting

Closed-loop Control of Penicillin Delivery (CLCPD)

Healthy Volunteers

United Kingdom
Johnson & Johnson Surgical Vision, Inc.

Active, not recruiting

Proof-of-concept Study for a New Intraocular Lens, MODEL C0001

Cataract

France
NewAmsterdam Pharma

Completed

Proof-of-concept, Open-label Study in Patients With Early Alzheimer's Disease

Early Alzheimer's Disease

Netherlands
Imperial College London

Completed

Minimally Invasive Sensing of Beta-lactam Antibiotics (MISBL)

Healthy Volunteers

United Kingdom
Bioverativ, a Sanofi company

Active, not recruiting

Proof-of-concept Study for SAR445088 in Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Canada, Spain, China, Italy, United States, France, Germany, Netherlands, Poland, Serbia
Sanofi

Active, not recruiting

Proof-of-concept Study for SAR441344 (Frexalimab) in Relapsing Multiple Sclerosis

Multiple Sclerosis

Bulgaria, Canada, Turkey, Spain, United States, Czechia, France, Germany, Russian Federation, Ukraine
Novadip Biosciences
PrimeVigilance; Data Investigation Company Europe (DICE)

Active, not recruiting

Proof-of-concept Study With NVDX3 for Treatment of Distal Radius Fractures.

Distal Radius Fractures

Luxembourg
Sheffield Children's NHS Foundation Trust

Completed

Proof-of-concept Study of 'JIA Toolbox' for Children and Young People (CYP) With Juvenile Idiopathic Arthritis (JIA) (JIA Toolbox)

Rheumatologic Disease

United Kingdom
City, University of London

Completed

Proof-of-concept Study of LUNA Intervention in Aphasia (LUNA)

Stroke | Aphasia

United Kingdom
Imperial College London

Completed

Measuring Hydrogen Peroxide in Exhaled Breath Condensate in HV

Proof Of Concept Study

United Kingdom
Oslo University Hospital
University Hospital, Akershus

Completed

Carbetocin Myocardium Trial 2014 Part 2 (CMT2014/2)

Pregnancy Complications

Norway
Genzyme, a Sanofi Company

Completed

Proof-of-concept Study to Assess the Efficacy, Tolerability and Safety of a Single Intraarticular Dose of GZ389988 Versus Placebo in Patients With Painful Osteoarthritis of the Knee

Osteoarthritis

Germany
Chiesi Farmaceutici S.p.A.

Completed

Functional Respiratory Imaging Study (DARWiIN)

Chronic Obstructive Pulmonary Disease

Belgium, Hungary
Azevan Pharmaceuticals
United States Department of Defense; Weill Medical College of Cornell University and other collaborators

Terminated

Proof-of-concept Study to Assess the Efficacy and Safety of SRX246 in Adults With PTSD

PTSD

United States
Teikoku Seiyaku Co., Ltd.

Terminated

Proof-of-concept Study of NSAID Hydrogel Patch in Treatment of Acute Pain

Ankle Sprain

United States
Nicole Lindenblatt
University Hospital, Zürich; Swiss Federal Institute of Technology; Zurich University... and other collaborators

Completed

Proof-of-concept Study of LymphMonitor 1.0 to Assess the Lymphatic Vessel Function

Lymphedema | Secondary Lymphedema

Switzerland
Cairo University

Unknown

Intravenous Tranexamic Acid Versus IV Carbetocin in Abdominal Myomectomy

Myomectomy
Royal Marsden NHS Foundation Trust
Janssen, LP

Unknown

Proof-of-concept Study of Ibrutinib in c-MYC and HER2 Amplified Oesophagogastric Carcinoma (iMYC)

Gastrooesophageal Cancer

United Kingdom
National University Hospital, Singapore
USHIO. INC

Completed

Proof-of-concept Study on Disinfection and Healing Acceleration Capabilities of 222nm Wave Length Narrow Band Ultraviolet Lighting Device

Ultraviolet Rays

Singapore
Universidad de Granada
University of Ulster

Completed

Prehabilitation for Being Active. A Feasibility Study in Fibromyalgia

Fibromyalgia

United Kingdom
Skane University Hospital

Withdrawn

Proof-of-concept Study of Forward Pharma (FP)187 in Patients With Mild/Moderate Psoriatic Arthritis

Psoriatic Arthritis

Sweden
Eiger BioPharmaceuticals

Terminated

Proof-of-concept Study Evaluating the Safety and Efficacy of EBP921 in Delta Hepatitis (HDV)

Hepatitis D

United States
Biogen
Elan Pharmaceuticals

Terminated

A Phase II, Multicenter, Open-Label, Long-Term Study of the Safety, Tolerability, and Efficacy of Intravenous Natalizumab in Subjects With Rheumatoid Arthritis Who Have Previously Participated in Study ELN100226-RA201

Rheumatoid Arthritis
Takeda

Completed

Intermittent Hormonal Therapy With Leuprorelin and Flutamide in the Treatment of Stage D2 or TxNxM1b,c

Prostatic Neoplasms
Tampere University Hospital
Tampere University; Aalto University; Åbo Akademi University

Completed

Proof-of-concept Study for Bioimpedance Based Monitoring of Venous Ulcers During Galvanic Stimulation

Patients With Lower Extremity Venous Ulcers | Patients With Localized Edema

Finland
Biogen
Elan Pharmaceuticals

Completed

Natalizumab High Titer Immunogenicity and Safety

Multiple Sclerosis

United States
Weill Medical College of Cornell University

Withdrawn

Oral Microdose Lupron Versus Luteal Estradiol Trial in Poor Responder In Vitro Fertilization (IVF) Patients (OMLET)

Infertility

United States
Heidelberg University

Completed

Infrahepatic Inferior Vena Cava Clamping During Hepatectomy (IVC CLAMP)

Hemorrhage

Germany
Acacia Pharma Ltd

Completed

Proof-of-concept (PoC) Study of APD515

Xerostomia in Advanced Cancer Patients

United Kingdom, Denmark
SciClone Pharmaceuticals

Completed

Proof-of-concept Study to Evaluate the Safety and Immunomodulatory Effects of SCV 07 as Monotherapy or in Combination With Ribavirin in Noncirrhotic Subjects With Chronic Hepatitis C Who Have Relapsed

Chronic Hepatitis C

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon

Lymphoma | Kidney Cancer | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Graft Versus Host Disease

United States
argenx

Not yet recruiting

A Safety and Efficacy Study of ARGX-119 in Adult Patients With Amyotrophic Lateral Sclerosis (ALS) (ReALiSe)

Amyotrophic Lateral Sclerosis
Guangdong Hengrui Pharmaceutical Co., Ltd

Not yet recruiting

A Study to Evaluate the Long-term Safety, Pharmacodynamics and Efficacy of SHR-1703 in Eosinophilic Asthma Patients

Eosinophilic Asthma Patients
NovoBliss Research Pvt Ltd
Winnox Cosmeceutics Sdn. Bhd

Not yet recruiting

A Clinical Study to Determine the Safety and Efficacy of Bio-Ray Knee Guard in Panelists With Varicose Vein and Knee Pain.

Varicose Veins With Self-declared Knee Pain
Merck Sharp & Dohme LLC

Not yet recruiting

A Study of Nemtabrutinib in Participants With Moderate Hepatic Impairment (MK-1026-015)

Hepatic Impairment (HI)
Tourcoing Hospital

Recruiting

Patient Satisfaction During Physiological Water or Land Birth: a Prospective Study in an French Tertiary Maternity Unit. (AQUAMODA)

Water Birth

France
CMC Ambroise Paré

Not yet recruiting

Connective Tissue of Pectoralis Major Muscle: Anatomical Study (USPEC)

Pectoralis Muscle

France
VA Office of Research and Development

Not yet recruiting

Pain and Smoking Study - Interactive Voice Response (PASS-IVR)

Smoking | Smoking Cessation | Pain

United States
Fujian Medical University Union Hospital

Recruiting

Multicenter Clinical Trial on the Effectiveness and Safety of Instillation of BCG and Alternative BCG Protocols for Intermediate and High-risk Non-muscle Invasive Bladder Cancer

Urinary Bladder Neoplasms | Treatment Outcome | Neoplasm Recurrence, Local | Multicenter Study | Immunotherapy, Active | BCG Vaccine

China
Fondazione Italiana Linfomi - ETS

Not yet recruiting

Retrospective-prospective Study to Evaluate Treatment Management and Outcomes of Patients With Waldenström's Macroglobulinemia (WM) Treated in Italy According to the Zanubrutinib (Brukinsa®) Compassionate Use Program (CUP) and in Common Practice Following Commercial Approval.

Waldenström's Macroglobulinemia (WM)

Italy
Incyte Corporation

Not yet recruiting

A Study to Evaluate the Effect of Povorcitinib on the QT/QTc Interval in Healthy Participants

Healthy Participants
Shandong University

Not yet recruiting

A Multicenter Randomized Controlled Study on the Treatment of Refractory CTIT With Romiplostim N01 Compared to Recombinant Human Thrombopoietin

CTIT-Chemotherapy Induced Thrombocytopenia
Addpharma Inc.

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Co-administration of AD-227A and AD-227B

Essential Hypertension

Search clinical trials for: Proof-of-concept study

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