Search clinical trials for: Protein Binding

Total 23112 results

Ionis Pharmaceuticals, Inc.

Not yet recruiting

ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)

Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome
Sohag University

Recruiting

Assessment Of Serum And Tissue Levels Of Cold-Inducible RNA-Binding Protein In Patients With Lichen Planus

Assessment, Self

Egypt
University Hospital, Tours

Not yet recruiting

DIAGALS: Relation Between Tar DNA Binding Protein(TDP)-43 et Nrf-2 in ALS: a Track to Improve Diagnosis and Prognosis of the Disease (DIAGALS)

Amyotrophic Lateral Sclerosis
Cairo University

Recruiting

Testicular Proteins for Sperm Retrieval Prediction Protein1, Testis-Expressed Gene 101, and Lectin Galactoside-binding Protein in Predicting Surgical Sperm Retrieval in Men With Non-Obstructive Azoospermia (Genomics)

Non-obstructive Azoospermia

Egypt
University Hospital Padova

Recruiting

Water and Electrolytes Content in HYpertension (WHYSKI) in the SKIn (WHYSKI)

Hypertension | Essential Hypertension | Hyperaldosteronism | Aldosteronism | Conn Adenoma | Aldosterone Disorder | Aldosterone-producing Adenoma | Bilateral Adrenal Hyperplasia

Italy
Centre Hospitalier Universitaire, Amiens
Binding site

Recruiting

The Distribution of Immunoglobulin Isotype in Polyclonal Hypergammaglobulinemia in Systemic and Autoimmune Diseases (ISOHYPE)

Autoimmune Diseases | Polyclonal Hypergammaglobulinemia

France
Ionis Pharmaceuticals, Inc.

Recruiting

Observational Study to Characterize Biomarkers and Disease Progression in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome

Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome

United States
Isala

Recruiting

Telemonitoring Among Patients With Multiple Myeloma (ITUMM)

Multiple Myeloma

Netherlands
St George's, University of London
University College, London

Recruiting

Medical Device (MD) Derived Pharmacokinetic (PK) Parameters for Vancomycin (MD-PK) (MD-PK)

Sepsis | Critical Illness | Septic Shock | Bacteremia | Infection, Bacterial | Antibiotic Side Effect | Antibiotic Resistant Infection | Adult Children

United Kingdom
Children's Hospital of Philadelphia
Jazz Pharmaceuticals; Stand Up To Cancer

Recruiting

Lurbinectedin in FET-Fused Tumors (LiFFT)

Ewing Sarcoma | Pediatric Cancer | Desmoplastic Small Round Cell Tumor | Undifferentiated Sarcoma

United States
Assiut University

Not yet recruiting

Pumilio1 (PUM1) Expression, Sickle Cell Anemia, β-thalassemia Intermedia

Sickle Cell Disease, Beta Thalassemia Intermedia
Assiut University

Not yet recruiting

Assessment of the Diagnostic Role of Serum Insulin-like Growth Factor Binding Protein-3 as a Potential Biomarker for Colorectal Cancer (CRC) in Egypt

Colorectal Cancer
Tenaya Therapeutics

Recruiting

Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM (MyPEAK-1)

Hypertrophic Cardiomyopathy

United States
China Medical University Hospital

Recruiting

The Roles of Human Microbiome and Vitamin D in the Development of Childhood Allergic Diseases

Pediatric

Taiwan
China Medical University Hospital

Recruiting

Vitamin D Treatment Effect for Atopic Dermatitis in Children

Atopic Dermatitis

Taiwan
China Medical University Hospital

Recruiting

The Association Between Human Microbiome and Vitamin D in Chronic Urticaria

Urticaria

Taiwan
The First Affiliated Hospital of Yangtze University

Not yet recruiting

Role of Calcium Binding Protein S100A12 in Diagnosis and Prognosis of Kawasaki Disease

Diagnoses Disease
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Guangzhou First People's Hospital; Sun Yat-Sen... and other collaborators

Recruiting

Combination of Sorafenib With Standard Therapy in Newly Diagnosed Adult CBF AML

Core Binding Factor Acute Myeloid Leukemia

China
Advice Pharma Group srl

Recruiting

KidneYou - Innovative Digital Therapy

Diabetes | Chronic Kidney Diseases | Tuberous Sclerosis | Albuminuria | Treatment Adherence | Arterial Hypertension | Treatment Adherence and Compliance | Nephronophthisis | Polycystic Kidney | Chronic Glomerulonephritis | Cystic Kidney Diseases | Cortical Cystic Disease | Cystic Diseases

Italy
Democritus University of Thrace

Recruiting

Combination of Inhaled DNase, Baricitinib and Tocilizumab in Severe COVID-19

COVID-19 Severe Respiratory Failure

Greece
Second Affiliated Hospital of Wenzhou Medical University

Not yet recruiting

Predictive Value of Maternal Serum Pentraxin 3 (PTX 3) and Heparin-binding Protein (HBP) for Chorioamnionitis in Preterm Premature Rupture of Membranes

Preterm Premature Rupture of Membrane
Region Skane
Lund University

Recruiting

Biomarkers for Ventilator-associated Pneumonia (VAPmarkers)

Pneumonia, Ventilator-Associated

Sweden
National Taiwan University Hospital

Recruiting

Latent TGF-β-binding Proteins Affect the Fibrotic Process in Renal Impairment and Cardiac Dysfunction

Acute Coronary Syndrome | Acute Coronary Syndrome With Renal Dysfunction

Taiwan
University of Tennessee
AstraZeneca; Vanderbilt University Medical Center

Recruiting

Oral Adherence in Hematological Oncology Agents and Impact on Comorbid Therapy Adherence

Multiple Myeloma | Chronic Lymphocytic Leukemia | Chronic Myeloid Leukemia | Multiple Chronic Conditions

United States
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Retinol-binding Protein 4 (RBP4) Metabolizm in Type 2 Diabetes Progression and Associated Cardiovascular Complications (RMTACC)

Diabetes Mellitus, Type 2

China
Azienda Sanitaria-Universitaria Integrata di Udine

Recruiting

Optimized Antibiotic Therapy in Patients With Subarachnoid Haemorrhage (ES) and Cerebral Haemorrhage (EC) (TANDEM)

Subarachnoid Hemorrhage | Therapeutic Drug Monitoring | Intracerebral Hemorrhage

Italy
Koç University
Vifor Pharma; Abdi Ibrahim Ilac San. ve Tic A.S.

Recruiting

Prevalence and Clinical Associates of Iron Deficiency in Patients With Atrial Fibrillation (AID-AF)

Iron-deficiency | Atrial Fibrillation

Turkey
Niguarda Hospital

Recruiting

Midostaurin Associated With Standard Chemotherapy in Patients With Core-binding Factor Leukemia (AML FLT3)

Core Binding Factor Acute Myeloid Leukemia (CBF-AML)

Italy
Paul M. Tulkens

Recruiting

Plasma Protein Binding and PK/PD of Total and Unbound Temocillin Non-ICU Patients (TEMODELTA)

Pharmacokinetics | Infection | Infections, Bacterial | Drug Monitoring | Antibacterial Agents | Temocillin

Belgium
Mayo Clinic

Recruiting

Assessment of Hyperphosphorylated Tau PET Binding in Primary Progressive Aphasia and Frontotemporal Dementia (SLD3)

Primary Progressive Aphasia | Behavioral Variant of Frontotemporal Dementia | Frontotemporal Dementia, Behavioral Variant

United States
University of Pisa

Recruiting

TyrosIne Kinase Inhibitors in Chronic Myeloid Leukemia: Efficacy and Tolerability. The TIKlet Study (TIKlet)

Chronic Myeloid Leukemia

Italy
McGill University Health Centre/Research Institute...

Recruiting

Longitudinal Natural History Study of Patients With Peroxisome Biogenesis Disorders (PBD)

Peroxisome Biogenesis Disorder | Zellweger Spectrum Disorder | RCDP - Rhizomelic Chondrodysplasia Punctata | D-Bifunctional Protein Deficiency | Alpha-Methylacyl-CoA Racemase Deficiency | Peroxisomal Acyl-CoA Oxidase Deficiency | Peroxisomal Acyl-CoA Oxidase 2 Deficiency | ATP Binding Cassette Subfamily... and other conditions

Canada
University of Giessen

Active, not recruiting

Perioperatively Assessed Biomarker I-FABP Level for Prediction of Acute Mesenteric Ischemia and Its Correlation With Acute Kidney Injury, Followed by Extracorporeal Circulation (aMIKI) (aMIKI)

Acute Kidney Injury | Acute Mesenteric Ischemia | Cardiac Surgery With Cardiopulmonary Bypass | Non-Occlusive Mesenteric Ischaemia

Germany
University of Pennsylvania

Suspended

Mendelian Reverse Cholesterol Transport Study

Lipid Metabolism, Inborn Errors | Cholesterol, HDL | Tangier Disease | LCAT Deficiency | Cholesteryl Ester Transfer Protein (CETP) Deficiency

United States
Shandong University
Fudan University; Chinese Nutrition Society

Suspended

SREBF1 Polymorphism and Egg Yolk on Cardiovascular Disease Risk in Healthy Young Adults: a Randomised, Two-period, Single Blinded, Crossover Trial

Healthy | GEN1 Gene Mutation

China
Columbia University
Osteoporosis Center of Armenia

Active, not recruiting

Vitamin D in Armenia: Vitamin D Repletion Strategies With Dibase, and Vitamin D and Vitamin D Binding Protein and COVID

Vitamin D Deficiency

Armenia
Sumitomo Pharma America, Inc.

Active, not recruiting

Study of DSP-0390 in Patients With Recurrent High-Grade Glioma

Glioblastoma Multiforme | High Grade Glioma

United States, Japan
National Center for Global Health and Medicine,...

Active, not recruiting

Risk Stratification of COVID-19 Using Urine Biomarkers

Covid19 | Urine | Acute Respiratory Failure With Hypoxia | Biomarker

United States, Brazil, Denmark, Japan, Philippines
University of Ulm

Completed

Randomized Phase III Study of Intensive Chemotherapy With or Without Dasatinib (Sprycel™)

Acute Myeloid Leukemia (AML)

Germany, Austria
Centro de Investigación en Alimentación y Desarrollo...

Completed

Dietary Intervention to Reduce Metabolic Endotoxemia

Obesity | Endotoxemia | Dietary Habits | Clinical Trial | Intestinal Microbiota

Mexico
Al-Azhar University

Completed

Regulatory T Cell With Related Interleukins in Periodontal Disease Progression

Periodontitis | Gingivitis

Egypt
University of Pennsylvania

Enrolling by invitation

Voices Of Individuals: Challenges and Experiences Of bvFTD

Frontotemporal Degeneration | Frontotemporal Dementia | Frontotemporal Dementia, Behavioral Variant | FTD

United States
University of North Florida

Completed

Happy Gut Study - Fermented Vegetables and Cardiovascular Biomarkers

Cardiovascular Diseases

United States
Karaganda Medical University
Ministry of Education and Science, Republic of Kazakhstan

Active, not recruiting

Bacterial Translocation Markers as Predictors of Infectious and Inflammatory Complications in Acute Bowel Obstruction

Systemic Inflammatory Response Syndrome | Colorectal Cancer | Intestinal Obstruction | Post-Op Complication | Colon Tumor

Kazakhstan
Halla Halldorsdottir
Karolinska Institutet

Completed

Heparin-Binding Protein and Heparins (HepHep)

Cardiovascular Diseases | Vascular Disease, Peripheral | Thromboprophylaxis

Sweden
Tianjin Medical University Second Hospital
The Second Hospital of Hebei Medical University; Tianjin Medical University... and other collaborators

Completed

Tissue Predictors of Abiraterone Benefit

Metastatic Castration-resistant Prostate Cancer

China
University Hospital, Strasbourg, France

Completed

Phenotyping and Genotyping of Duffy Antigen (DARC)

Plasmodium Vivax

France
Okan University

Enrolling by invitation

Ramadan Fasting, Microbiota and FABP4

Intermittent Fasting

Turkey
Canadian Myeloma Research Group

Completed

A Study Of Daratumumab, Low-Dose Oral Dexamethasone and Cyclophosphamide With Or Without Pomalidomide (DCDP)

Multiple Myeloma

Canada
Exelixis

Terminated

Study of XL114 in Subjects With Non-Hodgkin's Lymphoma

Chronic Lymphocytic Leukemia (CLL) | Small Lymphocytic Lymphoma (SLL) | Non-Hodgkin's Lymphoma (NHL) | Mantle Cell Lymphoma (MCL) | Activated B-Cell Type Diffuse Large B-Cell Lymphoma (ABC-DLBCL)

United States

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