Search clinical trials for: Proton pump inhibitors

Total 65706 results

Radboud University Medical Center

Completed

Phenotyping of High Dose Rifampicin (PHENORIF)

Tuberculosis

South Africa
Universidade de Passo Fundo

Completed

Spirulina Platensis for PPI Withdrawal (SpAReDPPI)

Dyspepsia | Gastro Esophageal Reflux Disease | Rebound Acid Hypersecretion
Addpharma Inc.

Completed

A Study to Compare PK, PD and Safety of the AD-214-02 and Rabeprazole

Gastroesophageal Reflux Disease

Korea, Republic of
Agios Pharmaceuticals, Inc.

Completed

A Study to Compare the Relative Bioavailability of Two AG-881 Formulations and Evaluate the Effect of Food and Omeprazole on the Pharmacokinetics of AG-881

Healthy Volunteers

United States
Addpharma Inc.

Completed

A Study to Compare PK, PD and Safety of the AD-214 10/600mg and Rabeprazole

Gastroesophageal Reflux Disease

Korea, Republic of
Gachon University Gil Oriental Medical Hospital
Catholic Kwandong University

Completed

Efficacy and Safety of Chuna Manual Treatment as an Adjunctive Therapy After Total Knee Arthroplasty: A Study Protocol for a Single-Center, Randomized, Assessor Blind, Parallel-Group Clinical Trial

Total Knee Replacement | Manipulation

Korea, Republic of
AHS Cancer Control Alberta
Cross Cancer Institute

Withdrawn

Effects of LBM and PPIs on Pharmacokinetics and Safety of Regorafenib (BAY 73-4506) in Cancer Patients

Metastatic Solid Malignancies | Locally Advanced Solid Malignancies

Canada
Takeda

Completed

Comparison of TAK-438 (Vonoprazan) to Lansoprazole in the Treatment of Gastric Ulcer Participants With or Without Helicobacter Pylori Infection

Gastric Ulcer

Taiwan, China, Korea, Republic of, Philippines
Hutchison Medipharma Limited

Completed

Surufatinib DDI With a PPI and a CYP3A Inducer

Healthy

United States
Hutchison Medipharma Limited

Completed

Fruquintinib Food Effect and Proton Pump Inhibitor Study

Food-drug Interaction | Drug Interaction

United States
Millennium Pharmaceuticals, Inc.

Completed

A Trial to Evaluate the Effect of the Proton Pump Inhibitor Esomeprazole on the Single-dose Pharmacokinetics (PK) of Oral TAK-906 in Healthy Adult Participants

Healthy Volunteers

United States
Shire

Completed

Study to Evaluate the Effect of Omeprazole on the Pharmacokinetics of SPD422 (Anagrelide Hydrochloride) in Healthy Adult Participants

Healthy Volunteers

United States
Shire

Completed

SSP-002358 Drug Interaction Study With Omeprazole

Healthy

Netherlands
Shire

Terminated

An Explorative Trial to Evaluate the Pharmacodynamic Effect of SPD557 on Reflux Parameters in Refractory GERD Patients

Gastroesophageal Reflux Disease

United Kingdom, Switzerland, Netherlands, Belgium, France, Germany
Yanjing Gao

Completed

PPIs and Gastroesophageal Varices in Liver Cirrhosis (PPIs: Proton Pump Inhibitors) (PPIs)

Liver Cirrhosis | Hypertension, Portal

China
Torax Medical Incorporated

Completed

Observational Study of Anti-Reflux Surgery

Gastroesophageal Reflux | Gastro Esophageal Reflux | GERD

Italy, Austria, Germany, United Kingdom
Acerta Pharma BV

Completed

A Study to Evaluate the One-way Interaction of Calcium Carbonate, Omeprazole, or Rifampin on ACP-196

Healthy Participants

United States
GlaxoSmithKline

Completed

GSK1325756 Relative Bioavailability Study in Healthy Elderly Subjects

Pulmonary Disease, Chronic Obstructive

United States
Yooyoung Pharmaceutical Co., Ltd.

Completed

Clinical Trial to Assess the Efficacy and Safety of YYD601 in the Treatment of Esophageal Reflux Disease (ERD)

Erosive Esophagitis

Korea, Republic of
Yooyoung Pharmaceutical Co., Ltd.

Completed

Clinical Trial to Assess the PK/PD of YYD601 20mg After Oral Administration if Healthy Adult Subjects (Phase1)

GERD

Korea, Republic of
Yooyoung Pharmaceutical Co., Ltd.

Completed

Clinical Trial to Assess the Efficacy and Safety of YYD601 in NERD Patients

Non-erosive Reflux Disease

Korea, Republic of
Acerta Pharma BV

Completed

A Study to Evaluate the Effect of an Acidic Formulation of Acalabrutinib (ACP-196), Acidic Beverage, or Grapefruit Juice on the Pharmacokinetics (PK) of ACP-196 Alone and Coadministered With Omeprazole

Healthy Volunteers

United States
Xijing Hospital of Digestive Diseases

Enrolling by invitation

Helicobacter Rescue Therapy With High-dose Esomeprazole and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy

Gastritis | Dyspepsia | Gastric Cancer | Peptic Ulcer | Helicobacter Pylori Infection

China
Fatih Sultan Mehmet Training and Research Hospital

Completed

THE EFFECT OF HELICOBACTER PYLORI ERADICATION THERAPY TO GASTRIC WALL THICKNESS BEFORE THE LAPAROSCOPIC SLEEVE GASTRECTOMY

Obesity, Morbid | Helicobacter Pylori Infection

Turkey
University Health Network, Toronto

Completed

Pantoprazole and Docetaxel for Men With Metastatic Castration-Resistant Prostate Cancer

Prostate Cancer

Canada
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Completed

Sequential Therapy Versus Triple Therapy for Helicobacter Pylori Eradication: a Placebo-controlled Trial

Helicobacter Pylori Infection

Italy
Wroclaw Medical University

Active, not recruiting

The Role of HRM and Specific Biomarkers of Inflammation in the Diagnosis of Patients With Dysphagia and Suspected EoE

Eosinophilic Esophagitis

Poland
Hoffmann-La Roche

Completed

A Study to Investigate the Effect of Esomeprazole and the Effect of Food on the Pharmacokinetics of Balovaptan in Healthy Volunteers

Autism Spectrum Disorder

United States
Rigshospitalet, Denmark

Terminated

Stereotactic Radiosurgery in Metastatic Spinal Cord Compression (Stereocord)

Neoplasm Metastasis | Spinal Cord Compression

Denmark
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Study Of Celecoxib Or Diclofenac And Omeprazole For Gastrointestinal (GI) Safety In High GI Risk Patients With Arthritis (CONDOR)

Arthritis, Rheumatoid | Osteoarthritis

Canada, Costa Rica, France, Korea, Republic of, Spain, Ukraine, Croatia, Taiwan, China, Serbia, Brazil, Singapore, Belgium, India, Colombia, Netherlands, Russian Federation, United Kingdom, Estonia, Portugal, Sweden, Hong Kong, Latvia, South Africa and more
XenoPort, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Arbaclofen Placarbil (XP19986) as Adjunctive Therapy in Subjects With Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease

United States, Canada
Mackay Memorial Hospital

Completed

Intraluminal Mono-antibiotic Therapy for Helicobacter Pylori Infection - A Comparison of Levofloxacin Powder and Levofloxacin Solution

Helicobacter Pylori Infection

Taiwan
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Comparison of Small Bowel Lesions Associated With Celecoxib Versus Ibuprofen Plus Omeprazole

Bowel Diseases, Inflammatory

United States
Sir Ganga Ram Hospital

Completed

Helicobacter Pylori Eradication in Functional Dyspepsia

Dyspepsia | Helicobacter Pylori Infection

India
Addpharma Inc.

Completed

A Study to Compare PK, PD and Safety of the AD-206 and Esomeprazole

Gastritis

Korea, Republic of
Dexa Medica Group

Terminated

Efficacy and Safety of DLBS2411 in the Management of GERD

Gastroesophageal Reflux Disease (GERD)

Indonesia
Assiut University

Completed

Esomeprazole in Treatment of Early Onset Preeclampsia (ESOPE Trial)

Preeclampsia

Egypt
Fifth Affiliated Hospital, Sun Yat-Sen University

Unknown

The Effect of PPI in Preventing Gastroesophageal Reflux Disease of Seafarers

Gastroesophageal Reflux Disease
Children's Hospital Srebrnjak
Belupo; University Hospital Center Sisters of Charity, Zagreb, Croatia

Completed

Omeprazole 20 mg in Patients With Laryngopharyngeal reﬂux and Comorbid Chronic Rhinosinusitis

Chronic Rhinosinusitis (Diagnosis) | Laryngopharyngeal Reflux
Millennium Pharmaceuticals, Inc.

Completed

A Study to Assess the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics (PK) of TAK-931 in Participants With Advanced Solid Tumors

Neoplasms, Advanced Solid

Netherlands
Shanghai Zhongshan Hospital

Unknown

Bismuth-Metronidazole Triple Therapy for H. Pylori First-line Treatment

Helicobacter Pylori Infection

China
Novartis Pharmaceuticals

Completed

Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors

Advanced Solid Tumors, Excluding Breast Cancer

United States
Assistance Publique - Hôpitaux de Paris

Unknown

The Incidence and Risk of Vein Infusion Phlebitis After Intravenous Infusion of Proton Pump Inhibitors (VeinIPP)

Vein Infusion Phlebitis

France
Brooklyn ImmunoTherapeutics, LLC

Completed

A Phase 2 Clinical Trial of the Safety and Effects of IRX-2 in Treating Patients With Operable Head and Neck Cancer

Squamous Cell Carcinoma of the Head and Neck
Fundación Pública Andaluza para la Investigación...

Unknown

Response to Oral Lansoprazole of Inorganic Pyrophosphate Levels in Patients With Grönblad-Stranberg Disease (Pseudoxanthoma Elasticum) (FIMPXE2016-01)

Grönblad-Stranberg Disease (Pseudoxanthoma Elasticum)

Spain
Novartis Pharmaceuticals

Completed

Evaluate the Effects of Patupilone on the Pharmacokinetics of Midazolam and Omeprazole in Patients With Advanced Malignancies

Solid Tumors

United States
Radboud University Medical Center
Merck Sharp & Dohme LLC

Completed

Pharmacokinetic Study of the HCV Protease Inhibitor Bo-cePRevir and the Proton Pump Inhibitor OMeprazOle (PROMO) (PROMO)

HCV Infections | Gastric Acid-related Disorders

Netherlands
Hanmi Pharmaceutical Company Limited

Completed

Efficacy and Safety of HIP1601 Capsule

Erosive Gastroesophageal Reflux Disease

Korea, Republic of
Kaohsiung Veterans General Hospital.

Completed

Comparing the Efficacy of Reverse Hybrid Therapy and Concomitant Therapy

Helicobacter Pylori Infection

Taiwan
Icahn School of Medicine at Mount Sinai

Withdrawn

Whether Proton Pump Inhibitors, Administered Prior to or After Surgery, Can Reduce the Incidence and/or Severity of Difficulty Swallowing Foods and/or Liquids,Following Anterior Cervical Surgery

Dysphagia | GERD | Degenerative Joint Disease

United States

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