Search clinical trials for: Purine-Pyrimidine Metabolism, Inborn Errors

Total 15820 results

Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Clinical Trial of HR091506 Tablets in Treatment of Gout With Hyperuricemia in Adults

Gout With Hyperuricemia in Adults
Shanghai Institute Of Biological Products
The First Affiliated Hospital of Henan University of Science and Technology; First Affiliated Hospital Bengbu Medical College and other collaborators

Recruiting

A Phase Ib Clinical Trial of Peguricase for Injection With Methotrexate in Patients With Uncontrolled Gout.

Gout

China
Novilla Pharmaceuticals

Not yet recruiting

Treatment of Topical Ketorolac Gel in Acute Gouty Flare

Acute Pain | Gout Flare | Acute Gouty Arthritis

Australia
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Recruiting

A Study of SSGJ-613 in Gout Subjects Initiating Urate-Lowering Treatment.

Gout Arthritis

China
UNICANCER
Servier

Not yet recruiting

Safety of Trifluridine/Tipiracil in Patients With Dihydropyrimidine Dehydrogenase Deficiency Diagnosed With Metastatic Colorectal or Gastroesophageal Cancer (TRIFLUOX-DP)

Metastatic Colorectal Cancer | Metastatic Gastroesophageal Adenocarcinoma | DPD Deficiency
Amgen

Recruiting

A Trial to Investigate the Non-inferiority of Pegloticase Administered Every 4 Weeks (Q4W) With MTX Compared With Every 2 Weeks (Q2W) With MTX in Participants With Uncontrolled Refractory Gout

Gout

United States
Diakonhjemmet Hospital

Recruiting

The Remote Monitoring of Gout Feasibility Study (ReMonit Gout)

Gout

Norway
Thammasat University

Not yet recruiting

The Effects of Limb Elevation During Gout Flare Episodes

Gout Flare

Thailand
University of California, Los Angeles
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

UR+AIMS Gout Wearable Skin Uric Acid Monitor Study

Gout

United States
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Not yet recruiting

A Study of Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection in Chinese Participants With Acute Gout

Acute Gout
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Clinical Study of HR091506 Tablets in Treatment of Gout With Hyperuricemia in Adults

Gout With Hyperuricemia in Adults
National Human Genome Research Institute (NHGRI)

Recruiting

A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

Metabolic Disease | Purine-Pyrimidine Metabolism | AICDA, OMIM *605257, Immunodeficiency With Hyper-IgM, Type 2; HIGM2 | UNG, OMIM *191525, Hyper-IgM Syndrome 5 | NT5C3A<TAB>, OMIM *606224, Anemia, Hemolytic, Due to UMPH1 Deficiency | UMPS, OMIM *613891, Orotic Aciduria | DHODH, OMIM *126064,... and other conditions

United States
Tasly Pharmaceutical Group Co., Ltd

Not yet recruiting

A Study to Evaluate Efficacy and Safety of Qingzhu Granules in the Treatment of Acute Gouty Arthritis

Gouty Arthritis

China
Urica Therapeutics Inc.

Recruiting

Open Label PK, PD and DDI of Dotinurad and Allopurinol in Gout Patients With Hyperuricemia

Hyperuricemia | Gout

United States
Guangdong Provincial Hospital of Traditional Chinese...

Recruiting

Immediate Analgesic Effects of Cheek Acupuncture for Acute Gouty Arthritis (CAAGA)

Acute Pain | Acupuncture | Acute Gout Arthritis

China
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Not yet recruiting

The MAD Study of SSGJ-613 in Healthy Subjects

Arthritis, Gouty

China
GeneScience Pharmaceuticals Co., Ltd.
Huashan Hospital

Recruiting

Safety and Efficacy of Genakumab for Injection in Patients With Gout Flare (Gensci 048-203)

Gout Flare | Acute Gout

China
GeneScience Pharmaceuticals Co., Ltd.
Huashan Hospital

Not yet recruiting

Safety and Efficacy of Genakumab for Injection in Patients With Gout Initiating Urico-lowering Therapy (Gensci 048-202)

Acute Gout | Gout Initiating Urico-lowering Therapy

China
University Hospital, Strasbourg, France

Recruiting

Assessment of Physician Consideration of ePRO's, From Patients With Gout, Rheumatoid Arthritis, Sjogren's Syndrome or Systemic Lupus, on the Frequency of Therapeutic Adjustments (CAPTAIN)

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Sjogren's Syndrome | Gout

France
Lihua Duan

Not yet recruiting

Recombinant Human Tumor Necrosis Factor-α Receptor Ⅱ Fusion Protein in the Treatment of Acute Gout

Acute Gout

China
Jiangsu Atom Bioscience and Pharmaceutical Co.,...

Recruiting

Phase 2b/3 Study to Assess ABP-671 a Novel URAT1 Inhibitor in Participants With Gout

Gout

United States, Georgia, Australia, Guatemala, Taiwan
JW Pharmaceutical

Recruiting

A Therapeutic Confirmatory Study of Epaminurad Versus Febuxostat in Gout Patients (EPIC)

Gout

Korea, Republic of
RenJi Hospital
Westlake Therapeutics

Not yet recruiting

A Exploratory Trial of WTX221 in Refractory Gout Patients

Gout Tophus
Centre Hospitalier Saint Joseph Saint Luc de Lyon

Recruiting

NLRP3 Inflammasome Activation Among Patients During Acute Gout Flares (ActiNG)

Gout Arthritis

France
University Medicine Greifswald
Wuerzburg University Hospital; University of Göttingen

Recruiting

Prednisolone Versus Colchicine for Acute Gout in Primary Care (COPAGO)

Acute Gout

Germany
Shanton Pharma Co., Ltd.

Recruiting

Dose Finding Study to Evaluate Safety and Efficacy of 3 Dosages of SAP 001.

Gout

United States, Puerto Rico
InventisBio Co., Ltd

Recruiting

Phase II Study to Evaluate Efficacy and Safety of D-0120 in Combination With Allopurinol in Subjects With Gout

Gout

United States
Olatec Therapeutics LLC

Recruiting

Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare

Arthritis | Joint Pain | Gout | Gout Flare | Gouty Arthritis | Acute Gout Flare | Gout Attack

United States, Spain, France
Lille Catholic University
Variant Bio, Inc.

Recruiting

Genetic of Chronic Kidney Disease and Gout in New Caledonia (CALEDGOUTCKD)

Renal Insufficiency, Chronic | Gout

New Caledonia
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Recruiting

A Phase Ib/II Study of Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection in Chinese Participants With Acute Gout

Acute Gout

China
LG Chem

Recruiting

Tigulixostat, Phase 3 Study, Allopurinol Controlled in Gout Patients (EURELIA2)

Hyperuricemia | Gout | Gout Flare | Tophi

United States
LG Chem

Recruiting

Tigulixostat, Phase 3 Study, Placebo Controlled in Gout Patients (EURELIA1)

Hyperuricemia | Gout | Gout Flare | Tophi

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Prevalence of Abnormalities in Ultrasonography of Joint and Tendons in Patients With Gout (EchoGoutte)

Gout

France
Uskudar University

Recruiting

Physiotherapy Assessment Based on the ICF Model in The Lesch-Nyhan Syndrome: Case Report

Lesch-Nyhan Syndrome

Turkey
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Clinical Study of SHR4640 Tablets Combined With Febuxostat Tablets in the Treatment of Primary Gout and Hyperuricemia

Primary Gout and Hyperuricemia
University of Edinburgh

Not yet recruiting

Tight Control of Gouty Arthritis Compared to Usual Care (TICOGA)

Gout
Chinese University of Hong Kong

Recruiting

An Innovative Chinese Herbal Formula for the Treatment of Gout

Gout

Hong Kong
Merit University

Not yet recruiting

Effect of Aquatic Exercise and Traditional Physical Therapy on Gout in Hypertensive Menopausal Women With Hyperuricemia

Gout
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Trial of HR091506 Tablets in Treatment of Primary Gout With Hyperuricemia in Adults

Primary Gout With Hyperuricemia in Adults
The Affiliated Hospital of Qingdao University

Recruiting

To Evaluate Drug Interactions Between XNW3009, Febuxostat, and Colchicine in Patients With Gout

Gout

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Rasburicase Treatment in Chronic Gouty Arthritis

Chronic Gout

China
University Hospital, Rouen

Not yet recruiting

Immediate Prescription of a Hypouricemic Treatment, Febuxostat, Compared to Its Delayed Administration (FEFACRIGOU)

Gout
Assistance Publique - Hôpitaux de Paris
Canon Medical Systems, USA

Recruiting

Descriptive Analysis of Dual-energy Computed Tomography Exams of Adult Patients With Gout (DECTGOUT)

Gout

France
Second Affiliated Hospital, School of Medicine,...

Recruiting

Research and Development of a New Technology for Detection of Abnormal Excretion of Intestinal Uric Acid Involved in the Incidence of Gout

Single Nucleotide Polymorphism | Hyperuricemia | Gout | Gut Microbiota | Uric Acid | Genetic Loci | Feces

China
Massachusetts General Hospital
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Recruiting

Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout (TRUST)

Gout

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Anakinra vs Prednisone to Treat Gout Flare in Patients With Chronic Kidney Disease Stage 4/5 or Renal Transplantation (Ana4CKD)

Chronic Kidney Disease | Gout | Renal Transplantation

France
Assistance Publique - Hôpitaux de Paris

Recruiting

Treat-to-target by Email During Urate-lowering Therapy in Gout (GOUTEmail)

Hyperuricemia | Gout | Inflammatory Rheumatism | Posology Adjustment

France
University of Chicago

Recruiting

The PhOCus Trial: Implementation of Pharmacogenomic Testing in Oncology Care

Breast Cancer | Head and Neck Cancer | Gastrointestinal Cancer | Dihydropyrimidine Dehydrogenase Deficiency | UGT1A1 Gene Mutation

United States
Shanghai Yueyang Integrated Medicine Hospital

Not yet recruiting

Oral Huzhang Granules for Acute Gouty Arthritis

Gouty Arthritis
ProgenaBiome

Recruiting

A Pilot Study to Explore the Role of Gut Flora in Gout

Gout

United States

Search clinical trials for: Purine-Pyrimidine Metabolism, Inborn Errors

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